• 대한간호학회지
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• 제30권1호
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• pp.110-121
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• 2000

This study was designed to develop the life moking cessation program with multidisciplinary approach using the Bandura's theory of self-efficacy and confirm the effect of it on the self-efficacy and smoking amount in college students. For this purpose non-equivalent control group, pretest-posttest design was used. The participating subjects in this study were 46 male college freshmen, 23 in experimental and 23 in control group. The experimental group received the 8 sessions of lecture and small group discussions for 4 weeks and a telephone coaching program for a period of 8 weeks. The control group received 5 sessions of lecture without further treatments. The data was collected from March 15 to June 11, 1999, and analysed by SAS/PC program with $\chi$$^2$test, simple t, paired t test. The results were as follows. 1. The score of self-efficacy was significantly increased over time in the experimental group than those of the control group. 2. The amount of urine cotinine was decreased over time in the experimental group, number of cigarettes smoked a day were significantly decreased, and they were significantly less than those of the control group. In conclusion it was found that the Life Smoking Cessation Program with Multidisciplinary Approach was an effective nursing intervention for increasing self efficacy and reducing the amount of smoking in male college students. Therefore, future smoking cessation programs should always consider the concept of self-efficacy and ways to positively reinforce it.

• 생물정신의학
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• 제20권4호
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• pp.129-135
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• 2013

Aggression can be defined as 'behavior intended to harm another' which can be seen both from humans and animals. However, trying to understand aggression in a simplistic view may make it difficult to develop an integrated approach. So, we tried to explain aggression in a multidisciplinary approach, affected by various factors such as neuroanatomical structures, neurotransmitter, genes, and sex hormone. Parallel with animal models, human aggression can be understood with two phenomena, offensive aggression and defensive aggression. Neurobiological model of aggression give a chance to explain aggression with an imbalance between prefrontal regulatory influences and hyper-reactivity of the subcortical areas involved in affective evaluation, finally in an aspect of brain organization. Serotonin and GABA usually inhibit aggression and norepinephrine while glutamate and dopamine precipitate aggressive behavior. As there is no one gene which has been identified as a cause of aggression, functions between gene to gene interaction and gene to environment interaction are being magnified. Contributions of sex hormone to aggression, especially molecular biologic interaction of testosterone and regulation of estrogen receptor have been emphasized during the research on aggression. This multidisciplinary approach on aggression with types, neurochemical bases, and animal models can bring integrated interpretation on aggression.

• 보건행정학회지
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• 제28권3호
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• pp.233-239
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• 2018

A rapid decrease of total fertility rate to 1.08 in 2005 prompted the Korean government to plan and implement a '5-year plan for ageing society and population policy' starting from 2006. The 1st and 2nd 5-year plans had not shown any discernible impact on the fertility and the 3rd 5-year plan was launched in 2016. However, the fertility rate is going down further. The author reviewed the contents and assessment reports of the fertility promotion plan to suggest ideas for complementing the shortcomings of it. Author defined the major determinants of marriage and child birth as philosophy, politics, sense of value, social norm, culture, healthcare, and education. The plan was examined in view of these determinants. Transformation of Korea from an agricultural society to an industrialized society in a short period of time had brought about changes in most of the determinants of marriage and child birth; in particular philosophy and sense of value. These aspects were not put into consideration in the plan. Author suggested to launch a social education program for the general public to establish a sound philosophy of life, reform the sense of value on family, child birth and education, and cultivate the skill to draw a consensus through discussions on the social issues. A special program to promote marriage of women at the optimum age for child birth was proposed. The government should implement well balanced policy for economic development and labor. Multidisciplinary approach was recommended for these tasks.

• 한국CDE학회논문집
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• 제14권3호
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• pp.207-216
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• 2009

Modern engineering design problems involve complexity of disciplinary coupling and difficulty of problem formulation. Multidisciplinary design optimization can overcome the complexity and design optimization software or frameworks can lessen the difficulty. Recently, a growing number of new multidisciplinary design optimization techniques have been proposed. However, each technique has its own pros and cons and it is hard to predict a priori which technique is more efficient than others for a specific problem. In this study, a software system has been developed to directly solve MDO problems with minimal input required. Since the system is based on MATLAB, it can exploit the optimization toolbox which is already developed and proven to be effective and robust. The framework is devised to change an MDO technique to another as the optimization goes on and it is called a reconfigurable MDO framework. Several numerical examples are shown to prove the validity of the reconfiguration idea and its effectiveness.

• Journal of Microbiology and Biotechnology
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• 제27권6호
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• pp.1098-1105
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• 2017

Vesicular stomatitis virus G glycoprotein (VSV-G) has been widely used for pseudotyping retroviral, lentiviral, and artificial viral vectors. The objective of this study was to establish a potential approach for large-scale production of VSV-G. To this end, VSV-G was cloned with an N-terminal His-tag into Pichia pastoris expression vector pPIC3.5K. Three clones ($Mut^s$) containing the VSV-G expression cassette were identified by PCR. All clones proliferated normally in expansion medium, whereas the proliferation was reduced significantly under induction conditions. VSV-G protein was detected in cell lysates by western blot analysis, and the highest expression level was observed at 96 h post induction. VSV-G could also be obtained from the condition medium of yeast protoplasts. Furthermore, VSV-G could be incorporated into Ad293 cells and was able to induce cell fusion, leading to the transfer of cytoplasmic protein. Finally, VSV-G-mediated DNA transfection was assayed by flow cytometry and luciferase measurement. Incubation of VSV-G lysate with the pGL3-control DNA complex increased the luciferase activity in Ad293 and HeLa cells by about 3-fold. Likewise, incubation of VSV-G lysate with the pCMV-DsRed DNA complex improved the transfection efficiency into Ad293 by 10% and into HeLa cells by about 1-fold. In conclusion, these results demonstrate that VSV-G could be produced from P. pastoris with biofunctionalities, demonstrating that large-scale production of the viral glycoprotein is feasible.

• 한국디자인학회:학술대회논문집
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• 한국디자인학회 2001년도 Bulletin of The 5th Asian Design Conference International Symposium on Design Science
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• pp.19.2-19
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• 2001

• 디지털융복합연구
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• 제12권2호
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• pp.531-537
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• 2014

본 논문은 공주대학교 공과대학 학생들에게 다학제간 캡스톤 디자인을 운영하기 위한 모델을 제시한다. 여름방학 계절학기 기간 중에 공주대학교 공과대학에서 다학제간 캡스톤 디자인을 운영하였다. 다학제간 캡스톤 디자인에 참여한 학생들은 이전에 캡스톤 디자인 교과목을 수강하지 않은 서로 연관이 없는 5개 전공 학생들이다. 다양한 전공의 학생들에게 캡스톤 디자인작품을 완성하기 위해 센서 및 액츄에이터 등을 이용하는 아두이노 우노 마이크로 컨트롤러 제어보드를 사용하는 캡스톤 디자인 모델을 도입하였다. 만족도 평가를 통해 더 창의적이면서 현장감 있는 의미 있는 교육이 진행되었음을 알게 되었다. 이를 통해 다학제간 캡스톤 디자인 부분에서 앞으로의 가능성 있는 방향을 제시하였다.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2005년도 제24회 춘계학술대회논문집
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• pp.11-15
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• 2005

공중발사 방식은 일반적인 지상발사와 비교해 볼 때 많은 장점을 지니고 있다. 그러나 공중발사 로켓의 형상은 모선에 장착 시 많은 제한이 따르기 때문에 여러 해석분야를 통합한 시스템 설계가 필요하다. 시스템 설계는 순차적 최적화와 MDF 기법을 이용하여 수행되었다. 해석 모듈은 임무분석, 단배분, 추진해석, 형상, 중량해석, 공력해석, 궤적해석을 포함한다. 두 가지 기법 중 MDF 기법을 이용하였을 때 더 좋은 결과를 도출하였다. 시스템 최적화 결과 총 중량 1244.91 kg. 위성중량 7.5 kg, 총 길이 6.18m, 지름 0.60 m을 지닌 초음속 공중발사 로켓이 설계되었다.

• 한국항공우주학회지
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• 제33권12호
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• pp.26-32
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• 2005

공중발사 방식은 일반적인 지상발사와 비교해 볼 때 많은 장점을 지니고 있다. 그러나 공중발사 로켓의 형상은 모선에 장착 시 많은 제한이 따르기 때문에 여러 해석분야를 통합한 시스템 설계가 필요하다. 시스템 설계는 순차적 최적화와 MDF 기법을 이용하여 수행되었다. 해석 모듈은 임무분석, 단배분, 추진해석, 형상, 중량해석, 공력해석, 궤적해석을 포함한다. 두 가지 기법 중 MDF 기법을 이용하였을 때 더 좋은 결과를 도출하였다. 시스템 최적화 결과 총 중량 1244.91kg, 위성중량 7.5kg, 총 길이 6.36 m, 지름 0.60m을 지닌 초음속 공중발사 로켓이 설계되었다.

• Human Ecology Research
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• 제51권6호
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• pp.649-663
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• 2013

As cultural diversity has gained a great deal of attention and the social fabric of Korean society is redefined, the number of studies on multi-cultural family homes has been growing in the area of human ecology, but relevant research is rarely found on the subject of housing. While the emphasis of housing research is on multidisciplinary approaches and empirical research is highly valued, a theoretical and methodological platform for discussing the new rising agenda of multi-cultural family homes is lacking. The purpose of this study was to explore approaches to and to discuss the issues in research for multi-cultural family homes in terms of housing theories and multidisciplinary approaches. To understand the housing related needs of multi-cultural families, this study highlights social constructionism, the ecological perspective, and feminist epistemology. These three multidisciplinary approaches were useful for generating an ontological analysis of multi-cultural family homes. Further, this study highlights two housing related theories, the microsociological and housing pathways approaches, for dealing with multi-cultural family homes. In conclusion, the five approaches were useful for exploring issues in housing research on multi-cultural family homes with appropriate research methods like hermeneutics, quantitative, and qualitative methods, and field research. Insights into using perspectives and holistic approaches might be useful for solving the problems of multi-cultural family homes in Korea.