• Korean Journal of Radiology
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• v.23 no.12
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• pp.1260-1268
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• 2022

Objective: To propose standardized MRI-proton density fat fraction (PDFF) cutoff values for diagnosing hepatic steatosis, evaluated using contemporary PDFF measuring methods in a large population of healthy adults, using histologic fat fraction (HFF) as the reference standard. Materials and Methods: A retrospective search of electronic medical records between 2015 and 2018 identified 1063 adult donor candidates for liver transplantation who had undergone liver MRI and liver biopsy within a 7-day interval. Patients with a history of liver disease or significant alcohol consumption were excluded. Chemical shift imaging-based MRI (CS-MRI) PDFF and high-speed T2-corrected multi-echo MR spectroscopy (HISTO-MRS) PDFF data were obtained. By temporal splitting, the total population was divided into development and validation sets. Receiver operating characteristic (ROC) analysis was performed to evaluate the diagnostic performance of the MRI-PDFF method. Two cutoff values with sensitivity > 90% and specificity > 90% were selected to rule-out and rule-in, respectively, hepatic steatosis with reference to HFF ≥ 5% in the development set. The diagnostic performance was assessed using the validation set. Results: Of 921 final participants (624 male; mean age ± standard deviation, 31.5 ± 9.0 years), the development and validation sets comprised 497 and 424 patients, respectively. In the development set, the areas under the ROC curve for diagnosing hepatic steatosis were 0.920 for CS-MRI-PDFF and 0.915 for HISTO-MRS-PDFF. For ruling-out hepatic steatosis, the CS-MRI-PDFF cutoff was 2.3% (sensitivity, 92.4%; specificity, 63.0%) and the HISTO-MRI-PDFF cutoff was 2.6% (sensitivity, 88.8%; specificity, 70.1%). For ruling-in hepatic steatosis, the CS-MRI-PDFF cutoff was 3.5% (sensitivity, 73.5%; specificity, 88.6%) and the HISTO-MRI-PDFF cutoff was 4.0% (sensitivity, 74.7%; specificity, 90.6%). Conclusion: In a large population of healthy adults, our study suggests diagnostic thresholds for ruling-out and ruling-in hepatic steatosis defined as HFF ≥ 5% by contemporary PDFF measurement methods.

• The korean journal of orthodontics
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• v.52 no.1
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• pp.3-19
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• 2022

Objective: The purpose of this study was to investigate the accuracy of one-step automated orthodontic diagnosis of skeletodental discrepancies using a convolutional neural network (CNN) and lateral cephalogram images with different qualities from nationwide multi-hospitals. Methods: Among 2,174 lateral cephalograms, 1,993 cephalograms from two hospitals were used for training and internal test sets and 181 cephalograms from eight other hospitals were used for an external test set. They were divided into three classification groups according to anteroposterior skeletal discrepancies (Class I, II, and III), vertical skeletal discrepancies (normodivergent, hypodivergent, and hyperdivergent patterns), and vertical dental discrepancies (normal overbite, deep bite, and open bite) as a gold standard. Pre-trained DenseNet-169 was used as a CNN classifier model. Diagnostic performance was evaluated by receiver operating characteristic (ROC) analysis, t-stochastic neighbor embedding (t-SNE), and gradient-weighted class activation mapping (Grad-CAM). Results: In the ROC analysis, the mean area under the curve and the mean accuracy of all classifications were high with both internal and external test sets (all, > 0.89 and > 0.80). In the t-SNE analysis, our model succeeded in creating good separation between three classification groups. Grad-CAM figures showed differences in the location and size of the focus areas between three classification groups in each diagnosis. Conclusions: Since the accuracy of our model was validated with both internal and external test sets, it shows the possible usefulness of a one-step automated orthodontic diagnosis tool using a CNN model. However, it still needs technical improvement in terms of classifying vertical dental discrepancies.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.46 no.9
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• pp.7-13
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• 2009

This paper presents a multi-channel transceiver that achieves a data rate of 3.125Gb/s/ch. The LVDS is used because of its noise immunity and low power consumption. And a pre-emphasis circuit is also proposed to increase the transmitter speed. On the receiver side, a low-power CDR(clock and data recovery) using 1/4-rate clock based on dual-interpolator is proposed. The CDR generates needed additional clocks in each recovery part internally using only inverters. Therefore each part can be supplied with the same number of 1/4-rate clocks from a clock generator as in 1/2-rate clock method. Thus, the reduction of a clock frequency relaxes the speed limitation and lowers power dissipation. The prototype chip is comprised of two channels and was fabricated in a $0.18{\mu}m$ standard CMOS process. The output jitter of transmitter is loops, peak-to-peak(0.31UI) and the measured recovered clock jitter is 47.33ps, peak-to-peak which is equivalent to 3.7% of a clock period. The area of the chip is $3.5mm^2$ and the power consumption is about 119mW/ch.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.16 no.11 s.102
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• pp.1075-1085
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• 2005

The purpose of this paper is to design the architecture for synchronization of MB-OFDM UWB system that is being processed the standardization for Alt-PHY of WPAN(Wireless Personal Area Network) at IEEE802.15.3a and to analyze the implementation loss due to 4 parallel synchronization architecture for design or link margin. First an overview of the MB-OFDM UWB system based on IEEE802.15.3a Alt-PHY standard is described. The effects of non-ideal transmission conditions of the MB-OFDM UWB system including carrier frequency offset and sampling clock offset are analyzed to design a full digital architecture for synchronization. The synchronization architecture using 4-parallel structure is then proposed to consider the VLSI implementation including algorithms for carrier frequency offset and sampling clock offset to minimize the effects of synchronization errors. The overall performance degradation due to the proposed synchronization architecture is simulated to be with maximum 3.08 dB of the ideal receiver in maximum carrier frequency offset and sampling clock offset tolerance fir MB-OFDM UWB system.

• ETRI Journal
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• v.26 no.3
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• pp.229-240
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• 2004

This paper reports on our development of a dual-mode transceiver for a CMOS high-rate Bluetooth system-onchip solution. The transceiver includes most of the radio building blocks such as an active complex filter, a Gaussian frequency shift keying (GFSK) demodulator, a variable gain amplifier (VGA), a dc offset cancellation circuit, a quadrature local oscillator (LO) generator, and an RF front-end. It is designed for both the normal-rate Bluetooth with an instantaneous bit rate of 1 Mb/s and the high-rate Bluetooth of up to 12 Mb/s. The receiver employs a dualconversion combined with a baseband dual-path architecture for resolving many problems such as flicker noise, dc offset, and power consumption of the dual-mode system. The transceiver requires none of the external image-rejection and intermediate frequency (IF) channel filters by using an LO of 1.6 GHz and the fifth order onchip filters. The chip is fabricated on a $6.5-mm^{2}$ die using a standard $0.25-{\mu}m$ CMOS technology. Experimental results show an in-band image-rejection ratio of 40 dB, an IIP3 of -5 dBm, and a sensitivity of -77 dBm for the Bluetooth mode when the losses from the external components are compensated. It consumes 42 mA in receive ${\pi}/4-diffrential$ quadrature phase-shift keying $({\pi}/4-DQPSK)$ mode of 8 Mb/s, 35 mA in receive GFSK mode of 1 Mb/s, and 32 mA in transmit mode from a 2.5-V supply. These results indicate that the architecture and circuits are adaptable to the implementation of a low-cost, multi-mode, high-speed wireless personal area network.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.4
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• pp.80-87
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• 2007

In this paper, link-level performance of a OFDMA technique, which has been considered as a standard for 802.16, 802.20, 3G-LTE, WiMax, and WiBro, is evaluated for next-generation wireless communication systems. While many researches have focused on uncoded forward-link performances, this paper provides a coded performance of a reverse-link OFDMA system. Performance degradation due to time offset among reverse-link users and frequency offset during FFT process is investigated. Transmitter and receiver antenna diversity techniques are used to overcome performance degradation. Performance of a OFDMA system is compared with a CDMA system in terms of FER and throughput to emphasize the advantage of OFDMA system for a reverse-link. Finally, under given specification, Eb/No required to achieve the maximum throughput of a reverse-link is proposed considering various coded rates and antenna permutations.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.8C
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• pp.806-813
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• 2009

This paper presents a modem chip design for high-speed wireless communications. Among the high-speed communication technologies, we design the UWB (Ultra-Wideband) modem SoC (System-on-Chip) Chip based on a MB-OFDM scheme which uses wide frequency band and gives low frequency interference to other communication services. The baseband system of the modem SoC chip is designed according to the standard document published by WiMedia. The SoC chip consists of FFT/IFFT (Fast Fourier Transform/Inverse Fast Fourier Transform), transmitter, receiver, symbol synchronizer, frequency offset estimator, Viterbi decoder, and other receiving parts. The chip is designed using 90nm CMOS (Complementary Metal-Oxide-Semiconductor) procedure. The chip size is about 5mm x 5mm and was fab-out in July 20th, 2009.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.26 no.12A
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• pp.2027-2035
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• 2001

In this paper, we present an audio stream delivery using the AMR (Adaptive Multi-Rate) coder that was adopted by ETSI and 3GPP as a standard vocoder for next generation IMT-2000 service in which includes combined sender (FEC) and receiver reconstruction technique in the Internet. By use of the media-specific FEC scheme, the possibility to recover lost packets can be much increased due to the addition of repair data to a main data stream, by which the contents of lost packets can be recovered. The AMR codec is based on the code-excited linear predictive (CELP) coding model. So we use a frame erasure concealment for CELP-based coders. The proposed scheme is evaluated with ITU-T G.729 (CS-ACELP) coder and AMR - 12.2 kbit/s through the SNR (Signal to Noise Ratio) and the MOS (Mean Opinion Score) test. The proposed scheme provides 1.1 higher in Mean Opinion Score value and 5.61 dB higher than AMR - 12.2 kbit/s in terms of SNR in 10% packet loss, and maintains the communicab1e quality speech at frame erasure rates lop to 20%.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.1
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• pp.79-85
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• 2016

Recently, visible light communication(VLC) is being actively researched as green wireless communication services are drawing attention. Currently, VLC mostly uses LED for transmission and PD(Photo Diode) for receiving. However, this kind of system has limited applications. Therefore, we design and propose in this paper, a LED-to-LED two way VLC system that doesn't use PD(Photo Diode). This system has the following features and contributions. First, this system uses just LED at both transmitter and receiver with analog switch, Second, this system support both one-way communication and two way communication together. One way communication can support multi-hop communication. The performance evaluation of the proposed system is conducted at a place with standard light. We test the success or failure of one way communication by changing distance and baud rate while test the success and failure of two way communication by changing distance. We expect that the proposed LED-to-LED system in this paper can be applied for various application fields.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.10
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• pp.2307-2314
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• 2015

This paper focuses on the generation algorithm of BeiDou pseudorange correction (PRC) and simulation based performance verification for design of Differential Global Navigation Satellite System (DGNSS) reference station and integrity monitor (RSIM) in order to prepare for recapitalization of DGNSS. First of all, it discusses the International standard on DGNSS RSIM, based on the interface control document (ICD) for BeiDou, estimates the satellite position using satellite clock offset and user receiver clock offset, and the system time offset between Global Positioning System (GPS) and BeiDou. Using the performance verification platform interfaced with GNSS (GPS/BeiDou) simulator, it calculates the BeiDou pseudorange corrections , compares the results of position accuracy with GPS/DGPS. As the test results, this paper verified to meet the performance of position accuracy for DGNSS RSIM operation required on Radio Technical Commission for Maritime Services (RTCM) standard.