• Journal of Korea Water Resources Association
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• v.40 no.8
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• pp.601-615
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• 2007

A selective withdrawal method has been widely used to control the quality of water released from a stratified reservoir and to improve downstream ecosystem habitats. Recently, several existing reservoir withdrawal facilities have been modified to accommodate multi-level water intake capabilities in order to adapt the impact of long-term discharge of high turbidity flow. The purpose of this study was to assess the effect of selective withdrawal method on the control of downstream turbidity and its impact on water quality in Daecheong Reservoir. A laterally integrated two-dimensional hydrodynamic and eutrophication model, which was calibrated and validated in the previous studies, was applied to simulate the temporal variations of outflow turbidity with various hypothetical selective withdrawal scenarios. In addition, their impacts on the algal growth as well as water quality constituents were analyzed in three different spatial domains of the reservoir The results showed that the costly selective withdrawal method would provide very limited benefits for downstream turbidity control during two years of consecutive simulations for 2004-2005. In particular, an excessive withdrawal from the epilimnion zone for supplying upper layer clean water resulted in movement of turbidity plume that contained high phosphorus concentrations upward photic zone, and in turn increased algal growth in the lacustrine zone.

• The Journal of the Korea Contents Association
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• v.18 no.9
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• pp.125-140
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• 2018

Due to rapid development of semiconductor technology, embedded systems have been developed from single-functional system to the multi-functional system. The system composed of software that has different criticality level is called Mixed-Criticality System. Currently, the project related to the Mixed-Criticality System is accelerating the efforts to seek the development direction and take technical initiatives led by EU and USA where the related industry has developed, but the movement in Korea is yet insignificant. Therefore, it is urgent to perform the research and project of various basic technologies to occupy the initiative for the related technology and market. In this paper, we analyze the trends of major project researches and developments related to the MCS. First, after defining the definition of the MCS and system model, we analyze the underlying technology constituting the MCS. In addition, we analyze the project trends of each country researching MCS and discuss the future research areas. Through this study, it is possible to grasp the research trends of the world in order to establish the research direction of the MCS and to lay the foundation for the integration into the military system.

• The Journal of the Korea Contents Association
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• v.20 no.7
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• pp.127-138
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• 2020

This study aims to analyze influences of self-perceived health, participation in social activities on life satisfaction and mediating effect of participation in social activities of the elderly by age group. For this, Structural Equation Model(SEM) was implemented by using data of the 6th wave of KLoSA with 2,106 young-olds and 2,219 old-olds. The results are as follows: The young-old elderly had higher level of self-perceived health, higher participation in social activities, and higher life satisfaction than the old-old elderly, and the mediating effect of participation in social activities was founded only in the young-old elderly. As a result of multi-group analysis, the influence of self-perceived health on life satisfaction was confirmed by no difference between both groups and the influence of self-perceived health on the participation in social activities was relatively higher in the old-old elderly. In the path of participation in social activities on the life satisfaction, the young-old elderly were found to have a significant effect. Through above results, the intervention plan considering the differences between groups was discussed in order to improve the elderly's life satisfaction.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.42 no.1
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• pp.9-26
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• 2005

In the pursuit of ever higher levels of performance, recent computer systems have made use of deep pipeline, dynamic scheduling and multi-issue superscalar processor technologies. In this situations, branch prediction schemes are an essential part of modem microarchitectures because the penalty for a branch misprediction increases as pipelines deepen and the number of instructions issued per cycle increases. In this paper, we propose a novel branch prediction scheme, direction-gshare(d-gshare), to improve the prediction accuracy. At first, we model a neural network with the components that possibly affect the branch prediction accuracy, and analyze the variation of their weights based on the neural network information. Then, we newly add the component that has a high weight value to an original gshare scheme. We simulate our branch prediction scheme using Simple Scalar, a powerful event-driven simulator, and analyze the simulation results. Our results show that, compared to bimodal, two-level adaptive and gshare predictor, direction-gshare predictor(d-gshare. 3) outperforms, without additional hardware costs, by up to 4.1% and 1.5% in average for the default mont of embedded direction, and 11.8% in maximum and 3.7% in average for the optimal one.

• BMB Reports
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• v.42 no.1
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• pp.59-64
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• 2009

Hepatitis B virus (HBV) infection is highly prevalent worldwide. The major challenge for current antiviral treatment is the elevated drug resistance that occurs via rapid viral mutagenesis. In this study, we developed AAV vectors to simultaneously deliver two or three shRNAs targeting different HBV-related genes. These vectors showed markedly better antiviral effects than ones that delivered a single shRNA in vitro. A dual shRNA expression vector (AAV-157i/1694i), which simultaneously expressed two shRNAs targeted the S and X genes of HBV, reduced HBsAg, HBeAg and HBV DNA levels by $87{\pm}4$, $80.3{\pm}2.6$ and $86.2{\pm}7%$ respectively, eight days post-transduction. In a mouse model of prophylactic treatment, HBsAg and HBeAg were reduced to undetectable levels and the serum HBV DNA level was reduced by at least 100 fold. These results indicate that AAV-157i/1694i generates potent anti-HBV effects and that the strategy of constructing multi-shRNA expression vectors may lead to enhanced anti-HBV efficacy and overcome the evading mechanism of the virus and thus the development of drug resistance.

• Journal of Preventive Medicine and Public Health
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• v.40 no.1
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• pp.23-28
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• 2007

Objectives : Chronic infections with hepatitis B or C and alcoholic cirrhosis are three well-known major risk factors for liver cancer. Diabetes has also been suggested as a potential risk factor. However, the findings of previous studies have been controversial in terms of the causal association. Therefore, the aim of this study was to evaluate the association between serum glucose levels and liver cancer development in a Korean cohort. Methods : Thirty-six liver cancer cases were identified in the Korean Multi-Center Cancer Cohort (KMCC). Baseline information on lifestyle characteristics was obtained via questionnaire. Serum glucose levels were measured at the study's enrollment. Relative risks (RRs) were estimated using a Cox proportional hazard regression model. The adjusting variables included age, gender, smoking history, alcohol consumption, body mass index, and hepatitis B surface antigen (HBsAg) seropositivity. Results : The RRs of serum glucose for liver caner were 1.20 (95% CI = 0.48-2.99) for the category of 100 to 125 mg/dL of serum glucose and 2.77 (95% CI = 1.24-6.18) for the >126 mg/dL serum glucose category (both compared to the <100 mg/dL category). In a subgroup analysis, the RR of serum glucose among those who were both HBsAg seronegative and non-drinkers was 4.46 (95% CI = 1.09-18.28) for those with glucose levels >100 mg/dL. Conclusions : The results of this study suggest that a high level of serum glucose can increase liver cancer risk independently of hepatitis infection and drinking history in Koreans. This study implies that glucose intolerance may be an independent risk factor for liver cancer.

• Economic and Environmental Geology
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• v.39 no.5 s.180
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• pp.525-535
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• 2006

A study on stream-groundwater exchange was performed using head and temperature data of stream water, streambed, and groundwater. Groundwater level and temperature were obtained from multi-depth monitoring wells in small-scale watershed. During the summer and winter season, time series of temperature data at streambed and groundwater were monitored for six months. In the winter time, we measured the temperature gradient between stream water and streambed. The observed data showed three typical types of temperature characteristics. First, the temperature of streambed was lower than that of stream water; second, the temperature of streambed and stream water was similar; and the last, the temperature of streambed was higher than that of stream water. The interconnections between the stream and the streambed were not homogeneously distributed due to weakly developed sediments and heterogeneous bedrock exposed as bed of the stream. The temperature data may be used in formal solutions of the inverse problems to estimate groundwater flow and hydraulic conductivity.

• Archives of design research
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• v.17 no.4
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• pp.375-384
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• 2004

The general tendency of approach to Korean Design History has been focusing its primary interest on the grand story in relation to the problems of modernization in political, economical and social aspects of Korea. In the discourse of modernization, however, there are two sides immanent in the modernization: there is the formal, institutional and authoritative modernization developed inside the capitalistic mode of production and the informal, individual and cultural modernization manifested in the mode of everyday lives. Especially, despite the viewpoint of the latter being embossed as an alternative approach in various areas including the academic world of history since the collapse of socialism, the historical recognition of the phenomena of modern design by the Korean design historians is more like the 'history from the above' that exists at the level of the discourse outside the reality rather than the 'history from the below' that exists within the ordinary life. To grant a sense of balance in such frame of historical understanding, it requires the restructuring the design history of Korea through the cultural perspectives from having the representation of mundane lives realized by the voluntary design activity of the common people as research subjects. One of the methods to acquire an answer to such problem is decoding, in the manner of 'cultural history', the life-long domestic artifact made by Madame Yang, Gap Jo (currently 87 years of age) who is a model of typical Korean mother. Through the historical rumination on the traces of unpretentious lives of the people that has been buried under the grand narrative of the Korean Design History, a new era aimed for the historical prospect of Korean design as cultural history will be possible by excavating the petit yet multi-layered meaning of Korean designs.

• Korean Journal of Child Studies
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• v.37 no.6
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• pp.83-94
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• 2016

Objective: The purpose of this study was to investigate differences in self-leadership and job involvement based on the education levels, majors, and teaching experiences of multicultural family home-visit instructors and the influence of self-leadership on job involvement. Methods: 668 home-visit instructors participated in the online survey from 140 multicultural family support centers in Seoul, 6 metropolitan cities, 9 provinces, and other cities and counties. Data were analyzed through frequency, percentages, Pearson's correlations, one-way ANOVA, $Scheff{\acute{e}}$ post-hoc test, and stepwise multi-regression using SPSS 21.0. Results: The main findings are as follows. First, instructors who were high school graduates had significantly higher scores in self-leadership than the other groups. There was only a significant difference in self-reward of self-leadership based on their majors. There were no significant differences in job involvement based on the education level and major. The greater their home-visit teaching experiences, the higher their scores in self-leadership and job involvement. Second, the stepwise multiple regression model showed that self-expectation, self-goal setting, constructive thinking, and rehearsal of self-leadership explained 49% of the total variance in job involvement. Conclusion: Even though the high school graduates had significantly higher scores in self-expectation, rehearsal, and constructive thinking of self-leadership than the other groups, over-generalization should be avoided because the sample size was relatively small. Based on the finding that greater home-visit teaching experiences was associated with higher self-leadership and job involvement, it would be necessary to improve working condition to prevent instructors from changing jobs. These findings stress the importance of providing opportunities for home-visit instructors to develop leadership, thus improving job involvement.

• Journal of Korea Water Resources Association
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• v.48 no.3
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• pp.149-158
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• 2015

It is well known that emergency outlet works have to be provided for the safety of dams. However, concept of emergency outlet works did not applied for the design of the most dams in Korea. Korean design standard for low-level outlet works does not provide enough design criteria which could be used in design of emergency outlet works. In this research, as-built status and hydraulic design criteria of outlet works, such as drawdown rate or hydraulic pressure due to the impounded water depth, were examined. Another relationship between drawdown rate and the dam slope stability was also examined with SEEP model. It was found that 25% reduction of impounded water depth decreases the pressure forces about 50%. Therefore, outlet works should be designed to drawdown properly at the beginning of the emergency. Seepage analysis of dam bodies showed that most of Korean dams could safely stand for 1m/day drawdown rate. Higher drawdown rate could result high discharge so the drawdown rate must be related with the flood risk of downstream. Finally, multi-stage design was recommended that faster discharge for the initial 25% of water depth in 7-10 days than the rest of it in 1-2 months.