• 한국약용작물학회지
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• 제26권6호
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• pp.490-497
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• 2018

Background: The growth process of ginseng seedlings is very important in producing good quality ginseng. This study was carried out to investigate the effects of different microclimates on the growth characteristics of ginseng seedlings in a multi-layer bed facility. Methods and Results: Ginseng seedlings were cultivated in a three-layer bed facility. The air temperatures on the first and second floors were similar, while that on the third floor was about $1-4^{\circ}C$ higher than that on the other floors. The vapor pressure deficit (VPD) was higher inside than on the outside of the facility, and that on third floor was the highest in the multi-layer bed system. The photosynthetic rate, chlorophyll fluorescence, and growth characteristics of ginseng seedlings did not significantly differ among the three floors. The yield of ginseng seedlings was the highest at $721g/1.62m^2$ on the first floor. Conclusions: It was found that microclimate plays an important role in growing ginseng seedlings in multi-layer bed facilities, and therefore proper environmental control is important. In addition, producing ginseng seedlings using multi-layer bed facilities is a technology that is expected to provide a way to overcome climate change and stabilize ginseng production.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2005년도 학술발표회(1)
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• pp.757-759
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• 2005

• 한국기계가공학회지
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• 제20권2호
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• pp.38-44
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• 2021

To cater to the transition from single-color to multicolor/multi-material printing, this paper proposes a cartridge-replacing type multi-nozzle Fused Depositon Modeling(FDM) three-dimensional (3D) printer. In the test printing run, tool change failure/wobble/layer shift occurred. It was confirmed that improper support was the cause of this tool change failure. As a solution, spline and electromagnetic cartridges were designed. Wobble was caused by machine vibration and the motor stepping out. To minimize wobble, an additional Z-axis was installed, and the four-point bed leveling method was used instead of the three-point bed leveling method. The occurrence of layer shift was ascribed to the eccentricity of the Z-axis lead screw. Therefore, slit coupler was replaced with an Oldham type. In addition to the mechanical supplementation, the control environment was integrated to prevent accidents and signal errors due to wire connections. Before the final test printing run, a rectifier circuit was added to the motor to secure precise control stability. The final test printing run confirmed that the wobble/layer shift phenomenon was minimized, and the maximum error between layers was reduced to 0.05.

• 한국해안·해양공학회논문집
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• 제21권2호
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• pp.127-135
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• 2009

Reid and Kajiura(1957)은 해저면에 무한한 깊이의 투수층이 존재할 경우에의 파의 감쇠율을 유도하였다. 본 연구에서는 유한한 깊이의 투수층이 존재할 경우에의 파의 감쇠율을 선형파이론을 이용하여 유도하였다. 그리고 이를 확장하여 해저면에 재질이 다른 2 층 또는 3 층의 투수층이 존재할 경우에 파의 감쇠율을 제시하였다. 다음으로 이를 완경사 방정식에 적용하여, 해저면에 투수층이 존재할 경우에의 파의 투과율을 계산하였으며, 1층 투수층이 존재할 경우의 수치계산결과를 Flaten and Rygg(1991)의 적분식 방법과 비교하여 검증하였다.

• Journal of Pharmaceutical Investigation
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• 제37권4호
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• pp.229-235
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• 2007

Multi-layered granules were prepared by a fluidized-bed coater and uniformed granules were obtained with a size range between $950{\sim}1000{\mu}m$ in diameter. The granule system was composed of three layers, i.e. seed layer with sugar sphere bead and a water-swellable polymer, middle layer with a drug, solubilizer and polymer, and the top layer of porous membrane with a polymeric binder. The aim of this work is to find out the dependence of a drug dissolution rate on the amount of a water-soluble binder and a solubilizer in the granule system. The results showed that the higher amount of hydrophilic binder in the porous membrane, gave the bigger pore size and porosity and made faster dissolution rate and also the higher amount of solubilizer in drug layer enhanced the dissolution rate of drug.

• Journal of Preventive Medicine and Public Health
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• 제5권1호
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• pp.43-48
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• 1972

5 bed sand filter, applying biological oxidation, was designed and studied on the treatment of water works. Never using any coagulant agent (drugs), which may cause water pollution in pre-treatment of head water, the auther attempt a high rate filtration by the microorganism (nitrofication bacteria) end plant which populate in multi layer sand beds. The result are as follows : In order to evaluate the oxygen effect on filtration, oxygen was injected in aeration tank attached to each filter tank while filtration, and $NH_3$ was tested as a representaiive ingredient. It was found out that the aeration method was more effective, with over 33% of $NH_3$ removal capacity, than the anerobic and this 5 bed filter showed double removal capacity of $NH_3$ by comparing with conventional sand bed (2 stage bed). According to the examination of two kind of head water, pre-treated with coagulant agent and activated carton, the filtration capacity was affected by the polluted condition of head water, resulting that lower value of pollution and slower velocity of filtration showed more efficiency of $NH_3$ removal. In this experiment $NH_3$ content tested in treated water had a fairly good correlation with others.

• 한국표면공학회지
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• 제52권6호
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• pp.321-325
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• 2019

Triso-type coating layers of silicon carbide and graphite on UO₂ paticulate nuclear fuel were prepared by using fluidized bed type chemical vapor deposition and self-propagating high temperature synthesis methods to make a coated nuclear fuel of a power plant for hydrogen mass-production. The source and carrier gases were the mixture of methyltrichlorosilane and propane, and inert argon. Chemical analysis and microstructure observation showed that the coated layers were inner graphite, middle silicon carbide and outer graphite. The elastic modulus and nano-hardness of the silicon carbide layer were 503 [GPa] and 36 [GPa], respectively.

• 폴리머
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• 제32권4호
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• pp.322-327
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• 2008

본 연구에서 제조한 다중층 펠렛은 수팽윤성 고분자를 포함하는 시드층, 모델 약물인 독사조신을 함유한 약물층, 약물의 방출을 제어하는 다공성막 그리고 지질층으로 구성되어 있으며, 유동층 코팅 방법을 이용하여 제조하였다. 펠렛을 구성하는 각각의 층에 다양한 특성을 가지는 고분자들의 블렌딩에 따른 독사조신의 약물방출 거동을 확인하기 위하여 히드록시프로필메틸셀룰로오스(HPMC)와 에틸셀룰로오스(EC)의 양을 달리하여 약물층을 제조하였고, 셀룰로오스 아세테이트(CA)와 $Eudragit^{(R)}$ RS의 비율을 달리하여 다공성막을 제조하였다. 그리고 지질층에 의한 방출 거동을 확인하고자 피마자유의 두께를 다르게 하여 펠렛을 제조한 결과, 대략 $1500{\mu}m$의 균일한 크기를 가지는 구형의 펠렛을 얻었다. 수용액에서 용출시험을 통하여 시간에 따른 약물방출량을 확인한 결과, 약물층에 첨가된 고분자 중, EC의 비율과 다공성막에서 CA의 비율이 증가하고, 피마자유층의 두께가 두꺼워지면 약물의 방출이 감소함을 알 수 있었다. 그리고 약물방출을 제어하는데 가장 큰 역할을 하는 다공성막의 다공형성거동 역시 SEM을 통해 확인하였다.

• Structural Engineering and Mechanics
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• 제13권2호
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• pp.187-209
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• 2002

The infrastructure system in the United States has been aging faster than the resource available to restore them. Therefore decision for allocating the resources is based in part on the condition of the structural system. This paper proposes to use neural network to predict the overall rating of the structural system because of the successful applications of neural network to other fields which require a "symptom-diagnostic" type relationship. The goal of this paper is to illustrate the potential of using neural network in civil engineering applications and, particularly, in bridge evaluations. Data collected by the Tennessee Department of Transportation were used as "test bed" for the study. Multi-layer feed forward networks were developed using the Levenberg-Marquardt training algorithm. All the neural networks consisted of at least one hidden layer of neurons. Hyperbolic tangent transfer functions were used in the first hidden layer and log-sigmoid transfer functions were used in the subsequent hidden and output layers. The best performing neural network consisted of three hidden layers. This network contained three neurons in the first hidden layer, two neurons in the second hidden layer and one neuron in the third hidden layer. The neural network performed well based on a target error of 10%. The results of this study indicate that the potential for using neural networks for the evaluation of infrastructure systems is very good.

• Journal of Pharmaceutical Investigation
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• 제38권6호
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• pp.387-392
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• 2008

Alfuzosin, an Alphal-adrenoceptor antagonist is used for the treatment of patients with voiding and in a lesser extent storage lower urinary tract symptoms (LUTS) associated to benign prostatic hyperplasia (BPH). The objective of this study was to formulate sustained release alfuzosin HCl granules and assess their formulation variables. The $Eudragit^{(R)}$ as a polymer, sustained release membrane, and dibutyl sebacate (DBS) as a plasticizer were used. Multi-coated alfuzosin HCl delivery systems composed of sugar sphere, various excipients, $Eudragit^{(R)}$ and HPMC (hydroxy propyl methyl cellulose), Cellulose Acetate were prepared by fluid-bed coater. Membrane layer were used $Eudragit^{(R)}$ RS PO and NE 30D. And the alfuzosin HCl coated beads were coated immediate release drug layer for initial burst. Its dissolution test was carried out compared to conventional products ($XATRAL^{(R)}$ XL). The release rate of drug from coated beads was higher than that from $XATRAL^{(R)}$ XL in pH 6.8.