• Asian-Australasian Journal of Animal Sciences
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• v.32 no.3
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• pp.309-319
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• 2019

Phytochemicals which exist in various plants and fungi are non-nutritive compounds that exert numerous beneficial bioactive actions for animals. In recent years following the restriction of antibiotics, phytochemicals have been regarded as a primal selection when dealing with the challenges during the producing process in the poultry industry. The selected fast-growing broiler breed was more fragile when confronting the stressors in their growing environments. The disruption of oxidative balance that impairs the production performance in birds may somehow be linked to the immune system since oxidative stress and inflammatory damage are multi-stage processes. This review firstly discusses the individual influence of oxidative stress and inflammation on the poultry industry. Next, studies related to the application of phytochemicals or botanical compounds with the significance of their antioxidant and immunomodulatory abilities are reviewed. Furthermore, we bring up nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and nuclear factor kappa B ($NF-{\kappa}B$) for they are respectively the key transcription factors involved in oxidative stress and inflammation for elucidating the underlying signal transduction pathways. Finally, by the discussion about several reports using phytochemicals to regulate these transcription factors leading to the improvement of oxidative status, heme oxygenase-1 gene is found crucial for Nrf2-mediated $NF-{\kappa}B$ inhibition.

• International conference on construction engineering and project management
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• 2015.10a
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• pp.523-526
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• 2015

In recent years, building commissioning has often been part of a standard delivery practice in construction, particularly in the high-performance green building market, to ensure the building is designed and constructed per owner's requirements. Commissioning, therefore, intends to provide quality assurance that buildings perform as intended by the design and often helps achieve energy savings. Commissioning, however, is not as widely adopted as its potential benefits are perceived. Owners are still skeptical of the cost-effectiveness claims by energy management and commissioning professionals. One of the issues in the current commissioning practice is that not every project is guaranteed to benefit from the commissioning services. This, coupled with its added cost, the commissioning service is not acquired with great acceptance and confidence by building owners. To overcome this issue, this paper presents a unique methodology to enhance owner's predicting capability of the degree of success of commissioning service using the Bayesian theorem. The paper analyzes a situation where a future building owner wants to use a pre-commissioning in an attempt to refine the success rate of the future commissioned building performance. The author proposes the Bayesian theorem based framework to improve the current commissioning practice where building owners are not given accurate information how much successful their projects are going to be in terms of energy savings from the commissioning service. What should be provided to the building owners who consider their buildings to be commissioned is that they need some indicators how likely their projects benefit from the commissioning process. Based on this, the owners can make better informed decisions whether or not they acquire a commissioning service.

• Journal of Information Processing Systems
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• v.20 no.2
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• pp.239-251
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• 2024

Coronavirus disease 2019 (COVID-19) has severely curtailed travelers' willingness to carpool and complicated the psychological processing system of travelers' carpooling decisions. In the post-COVID-19 era, a two-stage decision model under dynamic decision scenarios is constructed by tracking the psychological states of subjects in the face of multi-scenario carpooling decisions. Through a scenario experiment method, this paper investigates how three psychological variables, travelers' psychological distance to COVID-19, anticipated regret, and experienced regret about carpooling decisions, affect their willingness to carpool and re-carpool. The results show that in the initial carpooling decision, travelers' perception gap of anticipated regret positively predicts carpooling willingness and partially mediates between psychological distance to COVID-19 and carpooling willingness; in the re-carpooling decision, travelers' perception gap of anticipated regret mediates in the process of experienced regret influencing re-carpooling willingness; the inhibitory effect of experienced regret on carpooling in the context of COVID-19 is stronger than its facilitative effect on carpooling willingness. This paper tries to offer a fact-based decision-processing system for travelers.

• The Korean Journal of Rheology
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• v.10 no.4
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• pp.217-226
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• 1998

The anisotropy caused by the fiber orientation, which is inevitably generated by the flow during injection molding of short fiber reinforced polymers, greatly influences dimensional accuracy, mechanical properties, and other quality of the final product. Since the filling stage of the injection molding process plays a vital role in determining fiber orientation, an accurate analysis of flow field for the filling stage is needed. Unbalanced filling occurs when a complex or a multi-cavity mold is used leading to development of regions where the fiber suspension is under compression. It is impossible to make an accurate calculation of the flow field during filling with the analysis assuming incompressible fluid. A mold with four cavities with different filling times was produced to compare the numerical analysis results with the experimental data. There was a good agreement between the experimental and theoretical results when the compressibility of the polymer melt was considered for the numerical simulation. The fiber orientation states for compressible and incompressible fluids were also compared qualitatively as well as quantitatively in this study.

• Journal of Digital Contents Society
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• v.11 no.4
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• pp.479-486
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• 2010

A lot of local governments are trying to develop and brand the regional unique resources as a digital contents because of focusing on the intangible value of it's culture and economy of cultural industry. But every cultual contents business is not always successful. It must be successful on the condition that the cooperation of local government including citizens and private company's participation should make this business a good model of continuous potential growth power. The most important factor of it's business will be the realization of stable plan based on the design of business and carefully throughout plan. The other key factors are the analysis of the objective source and current market demands, the development of contents and story telling. Also the development of strategy of the content including OSMD(One-Source Multi-Device) and OSMU(One-Source Multi-Use) through the step analysis of the result must take into consideration. With the help of analyzing the successful cultural model "Honggildong cultual content business in Jangseong, Jeonnam" which is the representative case of OSMD and OSMU, this study attempts to suggest the successful strategy of regional culture resource brand. In order to provide a typical approach to the local government and cultural content industry which is trying to brand the regional cultual resource, this study researches the analysis of the development of Honggildong cultural resources and it's process step by step which was already finished it's first business stage.

• Strategy21
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• s.31
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• pp.57-84
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• 2013

North Korea's continuous threats and provocative behaviors have aggravated tension on the Korean peninsula particularly with the recent nuclear weapons test. South Korea's best way to cope with this situation is to maintain the balance among three policy directions: dialogue, sanctions, and deterrence. Among the three, I argue that deterrence should be prioritized. There are different sources of deterrence such as military power, economic power, and diplomatic clouts. States can build deterrence capability independently. Alternatively, they may do so through relations with other states including alliances, bilateral relations, or multilateral relations in the international community. What South Korea needs most urgently is to maintain deterrence against North Korea's local provocations through the enhancement of independent military capability particularly by addressing the asymmetric vulnerability between militaries of the South and the North. Most of all, the South Korean government should recognize the seriousness of the negative consequences that North Korea's 'Nuclear shadow strategy' would bring about for the inter-Korea relations and security situations in Northeast Asia. Based on this understanding, it should develop an 'assertive deterrence strategy' that emphasizes 'multi-purpose, multi-stage, and tailored deterrence whose main idea lies in punitive retaliation.' This deterrence strategy requires a flexible targeting policy and a variety of retaliatory measures capable of taking out all targets in North Korea. At the same time, the force structures of the army, the air force, and the navy should be improved in a way that maximizes their deterrence capability. For example, the army should work on expanding the guided missile command and the special forces command and reforming the reserve forces. The navy and the air force should increase striking capabilities including air-to-ground, ship-to-ground, and submarine-to-ground strikes to a great extent. The marine corps can enhance its deterrence capability by changing the force structure from the stationary defense-oriented one that would have to suffer some degree of troop attrition at the early stage of hostilities to the one that focuses on 'counteroffensive landing operations.' The government should continue efforts for defense reform in order to obtain these capabilities while building the 'Korean-style triad system' that consists of advanced air, ground, and surface/ subsurface weapon systems. Besides these measures, South Korea should start to acquire a minimum level of nuclear potential within the legal boundary that the international law defines. For this, South Korea should withdraw from the Nuclear Non-proliferation Treaty. Moreover, it should obtain the right to process and enrich uranium through changing the U.S.-South Korea nuclear cooperation treaty. Whether or not we should be armed with nuclear weapons should not be understood in terms of "all or nothing." We should consider an 'in-between' option as the Japanese case proves. With regard to the wartime OPCON transition, we need to re-consider the timing of the transition as an effort to demonstrate the costliness of North Korea's provocative behaviors. If impossible, South Korea should take measures to make the Strategic Alliance 2015 serve as a persisting deterrence system against North Korea. As the last point, all the following governments of South Korea should keep in mind that continuing reconciliatory efforts should always be pursued along with other security policies toward North Korea.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.677-685
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• 2018

In construction, schedule management is the basic but important step, for the effective schedule management, the preparation of the reasonable schedule table should be prioritized. In the design stage, the optimal construction period can be selected through comparison of various conditions and construction methods considering weather conditions and site characteristics. But, At the planning phase, it is difficult to select the effective method and calculate the proper construction period by the basic data(D/B) analysis. In this paper, the construction method considering characteristics of each type and conditions of existing city was selected. For the reasonable duration calculation, we analyzed the unit schedule for RC method for open type and Shield TBM method for tunnel type. The normal project duration of construction assuming of 1,200m of extension and every 200m of ventilation was prepared by integrating each unit schedule. It was analyzed that it took 893 days for the open type and 616 days for the tunnel type. The results of this study will help to make type selection and normal project duration more easily in the planning phase. If it is linked to the design stage, it will be easy to estimate the process and construction cost.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.26 no.2
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• pp.137-145
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• 2000

Carcinogenesis is a multi-stage process that generally consists of at least three steps; initiation, promotion, and progression. If one of these carcinogenic steps were suppressed or delayed, the cancer could be prevented. Cancer chemoprevention is defined to be inhibition or reversal of the carcinogenic process by the specific chemical agents and is a novel approach to cancer management alternative to conventional chemotherapy. Chlorophylln(CHL), a water-soluble derivative of chlorophyll, containing sodium and copper, has been known to be strong antimutagen in several test systems, but its mechanism of antimutagenic action is unknown. In the present experiment, the possibility of CHL as chemopreventive drugs on 7,12-dimethylbenz[a]anthracene(DMBA)-induced hamster buccal pouch carcinogenesis was investigated by mutagenicity test, carcinogenicity test, and frequency or spectrum of H-ras mutations in the both of DMBA-induced and chlorophylln-pretreated-DMBA induced tumor by polymerase chain reaction and non-isotopic restriction fragment length polymorphism. The treatment of CHL reduced the yields and multiplicity of the 0.5% DMBA-induced tumor, 86% to 62.5% and $3.7{\pm}0.6$ to $1.4{\pm}0.3$, respectively. The occurrence of histidine revertant by $20{\mu}mole$ DMBA was inhibited 25.6 to 81.7% by 1 to $5{\mu}M$ CHL in a dose-dependent manner. The mutation rates of H-ras gene in DMBA-induced and CHL-pretreated-DMBA induced tumor were 96%, 94% of which the most mutations were in codon 12/13. These results suggest that CHL inhibits the carcinogenic action of DMBA by the formation of complex between CHL and DMBA or the inhibition of the activation of DMBA in vivo. But CHL did not affect the mutation rates or its spectrum in already formed tumor.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• autumn
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• pp.96-101
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• 2001

Incheon International Airport Construction Project the biggest national multi-complex construction project in a single area in Korea, the necessity for introducing the Program Management System has been brought up from the development stage due to its specific characteristics and environment and with the Project Management Services Contract in December 1994 the system has been established and operated. At the time of contracting, there were controversies over the expected effect of the system since there were no related laws and regulations in domestic construction codes. Furthermore the situation was very hard in which some practical problems have been found in the process of applying and operating the system due to the lack of recognition and infrastructure in Korea. Incheon. In spite of these difficulties, thanks to the devotion and efforts of the project participants along with thoughtful concerns from the industries and the academies, the project goal has been successfully accomplished. This paper will analyze the various problems arose in the process of applying the Project Management System to Incheon International Airport and present more practical and desirable ways so that it can help to make the environment for properly settling Construction Management at the earliest.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.2
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• pp.288-301
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• 2002

A vacuum freeze drying experiment of skim milk solution in a cylindrical container is conducted to investigate the multi-dimensional drying characteristics of the process during the primary drying stage. Temperature histories at several positions are measured under the same process condition that is carefully controlled. Then the measured temperature histories at different positions are combined to produce instantaneous temperature distribution fields inside the cylindrical container. Along with the temperature measurement, the mass reduction history of the skim milk solution is also measured. From the measured temperature distribution curved configurations of sublimation interfaces and 2-dimensional heat transfer is inferred. The freeze drying under the present experimental setup is simulated with a calculation program that is based on a finite volume method with a moving grid system. Good agreements between the numerical and experimental results are observed. The present experimental results and the numerical approaches can be useful information in developing the analysis tools for practical vacuum freeze drying processes.