• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.8
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• pp.1424-1429
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• 2007

This paper presents a simple and reliable one-touch type multi-immunosensing lab-on-a-chip (LOC) detecting antibodies as multi-disease markers using electrochemical method suitable for a portable point-of-care system (POCS). The multi-stacked LOC consists of a PDMS space layer for liquids loading, a PDMS valve layer with 50 im in height for the membrane, a PDMS channel layer for the fluid paths, and a glass layer for multi electrodes. For the disposable immunoassay which needs sequential flow control of sample and buffer liquids according to the designed strategies, reliable and easy-controlled on-chip operation mechanisms without any electric power are necessary. The driving forces of sequential liquids transfer are the capillary attraction force and the pneumatic pressure generated by air bladder push. These passive fluid transport mechanisms are suitable for single-use LOC module. Prior to the application of detection of the antibody as a disease marker, the model experiments were performed with anti-DNP antibody and anti-biotin antibody as target analytes. The flow test results demonstrate that we can control the fluid flow easily by using the capillary stop valve and the PDMS check valves. By the model tests, we confirmed that the proposed LOC is easily applicable to the bioanalytic immunosensors using bioelectrocatalysis.

• Proceedings of the Korea Multimedia Society Conference
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• 2000.04a
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• pp.474-477
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• 2000

최근 3D 애니메이션 , 영화 특수효과 그리고 게임제작시 모션 캡처 시스템(Motion Capture System)을 통하여 실제 인간의 동작 및 표정을 수치적으로 측정해내어 이를 실제 애니메이션에 직접 사용함으로써 막대한 작업시간 및 인력 드리고 자본을 획기적으로 줄이고 있다. 그러나 기존의 모션 캡처 시스템은 고속 카메라를 이용함으로써 가격이 고가이고 움직임 추적에서도 여러 가지 문제점을 가지고 있다. 본 논문에서는 일반 저가의 카메라와 신경회로망 및 영상처리를 이용하여 얼굴 애니메이션용 모션 캡처 시스템에 적용할 수 있는 경제적이고 효율적인 얼굴 움직임 추적 기법을 제안한다.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.18 no.35
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• pp.123-130
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• 1995

The analytic hierarchy process(AHP) is a multi-criteria decision methodology developed by T.L.Saaty(1980). The AHP presents flexible, easily understood wry to assist the decision-marker in formulating his problem in a logical and rational manner. This paper addresses the concept of AHP and its application in the evaluation of nuclear and coal-fired power generations.

• Journal of Ocean Engineering and Technology
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• v.17 no.4
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• pp.1-7
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• 2003

A virtual reality technology for multipurpose numerical simulation is developed to reproduce and investigate a variety of ocean environmental problems in a 3D Numerical Wave Tank(NWT). The governing equations for solving incompressible fluid motion are Navier-Stokes equation and continuity equation. The Marker-Density function technique is adopted to implement the fully nonlinear freesurface kinematic condition. The marine environmental situations, i.e., waves, currents, etc., are reproduced by use of multi-segmented wavemakers on the basis of the so-called ″snake-principle″. In this paper, some numerical reproduction techniques for regular, and irregular waves, multi-directional waves, Bull's-eye wave. wave-current, and solitary wave are presented, and a model test in motion with large amplitude of roll angle is conducted in the developed 3D-NWT, using a overlaid grid system.

• Proceedings of the Korean Society of Computer Information Conference
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• 2012.07a
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• pp.13-14
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• 2012

본 논문에서는 멀티 터치 테이블을 중심으로 u-Learning 시스템을 제안한다. 멀티 터치 테이블에서 수업 진행 중 교사는 모바일로 멀티 터치 테이블을 제어함으로써 수업을 진행 및 관리하고, 학생들은 마커를 이용하여 멀티 터치 테이블과의 인터랙션을 통해 웹과 자동화된 과제 시스템을 이용함으로써 능동적인 학습참여를 할 수 있게 된다.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2002.10a
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• pp.174-180
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• 2002

A virtual reality technology for multipurpose numerical simulation is developed to reproduce and investigate a variety of ocean environmental problems in a 3D-Numerical Wave Tank. The governing equations for solving incompressible fluid motion are Navier-Stokes equation and continuity equation, and the Marker-Density function technique is adopted to implement the fully-nonlinear free-surface kinematic condition. The marine environmental situations, i.e. waves, currents, wind, etc., are reproduced by use of multi-segmented wavemaker on the basis of the so-called "snake-principle". In this paper, some numerical reproduction techniques for regular and irregular waves, multi-directional waves, Bull's-eye wave, wave-current, and solitary wave are presented, and a model test in motion with large amplitude of roll angle is conducted in the developed 3D-NWT, using a overlaid grid system.

• Journal of Digital Convergence
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• v.18 no.6
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• pp.425-433
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• 2020

Digilog book using augmented reality is a form that augmented reality is implemented by illuminating the camera embedded in the mobile image on the page registered as an image marker after downloading the application, which shows a fragmentary limitation in the content implementation method. Therefore, in this study, we proposed a pop-up multi-tracking method that enables two-way interaction in a digit log book using augmented reality technology. Through this, we commissioned an authorized agency to test the technical differentiation of augmented reality content for two prototypes of existing book-type Digilog Book and Pop-up-type Digilog Book. A test report was issued. The pop-up type digit log book suggested in this study enables the user to implement the interactive contents according to the user's action (movement). This can induce the interaction between the virtual image and the printed picture book and give the learner an interest and immersion, so that it is possible to express the interaction of the digital log book.

• The Journal of the Korea Contents Association
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• v.17 no.10
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• pp.94-101
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• 2017

This study is to compare and analyze the bioelectrical impedance values on the upper extremity (affected and non-affected side) in hemiplegic stroke patients. Experimental subjects were 24 stroke patients with hemiplegia undergoing stroke rehabilitation between October to November, 2015. Prediction marker, resistance, reactance, and phase angle were measured in the upper extremity (affected and non-affected side) of hemiplegic stroke patients, using MultiScan 5000, and then they were expressed as quantified values. The affected and non-affected side of upper extremity in stroke patients with hemiplegia exhibited significant differences in prediction marker, reactance, and phase angle (p<0.05). There were significant differences in the impedance values at the affected and non-affected side of hemiplegic stroke patients. Thus, the possibility of evaluating stroke patients undergoing clinical rehabilitation therapy was suggested.

• Korean Journal of Radiology
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• v.24 no.11
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• pp.1131-1141
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• 2023

Objective: Cortical iron deposition has recently been shown to occur in Alzheimer's disease (AD). In this study, we aimed to evaluate how cortical gray matter iron, measured using quantitative susceptibility mapping (QSM), differs in the clinical cognitive impairment spectrum. Materials and Methods: This retrospective study evaluated 73 participants (mean age ± standard deviation, 66.7 ± 7.6 years; 52 females and 21 males) with normal cognition (NC), 158 patients with mild cognitive impairment (MCI), and 48 patients with AD dementia. The participants underwent brain magnetic resonance imaging using a three-dimensional multi-dynamic multi-echo sequence on a 3-T scanner. We employed a deep neural network (QSMnet+) and used automatic segmentation software based on FreeSurfer v6.0 to extract anatomical labels and volumes of interest in the cortex. We used analysis of covariance to investigate the differences in susceptibility among the clinical diagnostic groups in each brain region. Multivariable linear regression analysis was performed to study the association between susceptibility values and cognitive scores including the Mini-Mental State Examination (MMSE). Results: Among the three groups, the frontal (P < 0.001), temporal (P = 0.004), parietal (P = 0.001), occipital (P < 0.001), and cingulate cortices (P < 0.001) showed a higher mean susceptibility in patients with MCI and AD than in NC subjects. In the combined MCI and AD group, the mean susceptibility in the cingulate cortex (β = -216.21, P = 0.019) and insular cortex (β = -276.65, P = 0.001) were significant independent predictors of MMSE scores after correcting for age, sex, education, regional volume, and APOE4 carrier status. Conclusion: Iron deposition in the cortex, as measured by QSMnet+, was higher in patients with AD and MCI than in NC participants. Iron deposition in the cingulate and insular cortices may be an early imaging marker of cognitive impairment related neurodegeneration.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.493-496
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• 2009

Many AR (Augmented Reality) applications have been interested in a marker-less tracking since the tracking methods give camera poses without attaching explicit markers. In this paper, we propose a new marker-less page recognition and tracking algorithm for an AR book application such as DigilogBook. The proposed method only requires orthogonal images of pages, which need not to be trained for a long time, and the algorithm works in real-time. The page recognition is done in two steps by using SIFT (Scale Invariant Feature Transform) descriptors and the comparison evaluation function. And also, the method provides real-time tracking with 25fps ~ 30fps by separating the page recognition and the frame-to-frame matching into two multi-cores. The proposed algorithm will be extended to various AR applications that require multiple objects tracking.