• Title/Summary/Keyword: Multi strategies

Search Result 791, Processing Time 0.03 seconds

Analysis of Methodologies for Prioritizing Climate Change Adaptation Measures (기후변화 적응대책 우선순위 선정을 위한 방법론 분석)

  • Chae, Yeora;Jo, Hyun-Ju
    • Journal of Environmental Policy
    • /
    • v.12 no.4
    • /
    • pp.23-44
    • /
    • 2013
  • Climate change affects human and natural environment. Many countries, including Korea, are trying to develop climate change adaptation strategies to minimize adverse impacts of climate change. To deal with climate change efficiently, decisions have to be made among many options. The objectives of this paper is to analyzes methodologies for prioritizing climate change adaptation measures. Each methodology has strength and weakness and information requirements are differ. We find multi-criteria analysis is one of useful tools considering current level of understanding on climate change adaptation. We suggest climate change risks(timing, likelihood, intensity of climate change impacts), feasibility of policy (equity, main-streaming, democracy), effectiveness (economic effectiveness, co-benefits, propagation effects) of adaptation measures as main evaluation criteria of prioritization.

  • PDF

Up-regulation of HOXB cluster genes are epigenetically regulated in tamoxifen-resistant MCF7 breast cancer cells

  • Yang, Seoyeon;Lee, Ji-Yeon;Hur, Ho;Oh, Ji Hoon;Kim, Myoung Hee
    • BMB Reports
    • /
    • v.51 no.9
    • /
    • pp.450-455
    • /
    • 2018
  • Tamoxifen (TAM) is commonly used to treat estrogen receptor (ER)-positive breast cancer. Despite the remarkable benefits, resistance to TAM presents a serious therapeutic challenge. Since several HOX transcription factors have been proposed as strong candidates in the development of resistance to TAM therapy in breast cancer, we generated an in vitro model of acquired TAM resistance using ER-positive MCF7 breast cancer cells (MCF7-TAMR), and analyzed the expression pattern and epigenetic states of HOX genes. HOXB cluster genes were uniquely up-regulated in MCF7-TAMR cells. Survival analysis of in slico data showed the correlation of high expression of HOXB genes with poor response to TAM in ER-positive breast cancer patients treated with TAM. Gain- and loss-of-function experiments showed that the overexpression of multi HOXB genes in MCF7 renders cancer cells more resistant to TAM, whereas the knockdown restores TAM sensitivity. Furthermore, activation of HOXB genes in MCF7-TAMR was associated with histone modifications, particularly the gain of H3K9ac. These findings imply that the activation of HOXB genes mediate the development of TAM resistance, and represent a target for development of new strategies to prevent or reverse TAM resistance.

Priority Setting and Technological Innovation Strategies for Future Growth Engine Industries: Focusing on the development of the Korea Future Technology Index (미래성장동력 선정을 위한 새로운 방법론 모색: 한국미래기술지수의 개발을 중심으로)

  • Bae, Yonh-Ho;Choi, Ji-Sun;Hwang, Seog-Won;Lee, Woo-Sung;Koh, Myoung-Ju
    • Journal of Technology Innovation
    • /
    • v.19 no.3
    • /
    • pp.85-114
    • /
    • 2011
  • This paper aims at developing a new index that represents the Korean new growth industries, which is named the Korea Future Technology Index(KOFTI). The KOFTI is designed to provide a reliable and econometric index based on which the Korean government searches for new growth engines. The KOFTI is composed of three individual indexes such as the Economic Impact Index, the Future Strategy Index, and the Technological Influence Index. The KOFTI is applied for 62 star brands, which have been promoted by the Korean government for the korean future industrial competitiveness. The top 13 leading industries are drawn from the calculation of the KOFTI for 62 star brands.

  • PDF

A Study on the Global Strategy and Challenges of Paperless Trade in Korea (한국 전자무역의 글로벌 전략과 과제에 관한 연구)

  • Yun, Soo-Young
    • International Commerce and Information Review
    • /
    • v.12 no.1
    • /
    • pp.3-33
    • /
    • 2010
  • Paperless trade is a new trade paradigm that has innovated on traditional trade procedures, which relied on manual work in the past, and applied an IT-based e-document standard. To realize paperless trade in Korea, a lot of efforts have been made. Korea has overcome many difficulties, a lack of awareness, trials and errors, etc. at the initial introduction stage and strived to establish a stable infrastructure through the government's policy support and active cooperation with the trade business communities and related organizations. Now, Korea became a well-known leader in IT industry, especially in the paperless trade infrastructure and strategic policies. The one-stop trading system named 'uTradeHub' is operated by a paperless trade service provider, Korea Trade Network(KTNET). uTradeHub includes trade finance and settlement, customs clearance and export and import logistics, improving trading procedures and reducing related expenses. Private-Public joint efforts from Korean government and private sectors which have respectively fulfilled their role and function with market-oriented practical policies and strategies has lead Korea a world leading country in paperless trade. Moreover, Korea expended its efforts to the global areas. Korea has started to activate multi-national paperless trade alliances such as PAA(Pan-Asia e-Commerce Alliance), ASEAL(Asia Europe Alliance for Paperless Trading) as well as established the bilateral cooperative networks with China and Taiwan. The one-stop trading system, uTradeHub should keep close cooperations between nations since trade itself is implemented in a cross-border ways. In the near future, it is expected uTradeHub can achieve best results in the simplification of procedures and cost savings when an international linkage is completely established with international cooperations.

  • PDF

Large Scale Incremental Reasoning using SWRL Rules in a Distributed Framework (분산 처리 환경에서 SWRL 규칙을 이용한 대용량 점증적 추론 방법)

  • Lee, Wan-Gon;Bang, Sung-Hyuk;Park, Young-Tack
    • Journal of KIISE
    • /
    • v.44 no.4
    • /
    • pp.383-391
    • /
    • 2017
  • As we enter a new era of Big Data, the amount of semantic data has rapidly increased. In order to derive meaningful information from this large semantic data, studies that utilize the SWRL(Semantic Web Rule Language) are being actively conducted. SWRL rules are based on data extracted from a user's empirical knowledge. However, conventional reasoning systems developed on single machines cannot process large scale data. Similarly, multi-node based reasoning systems have performance degradation problems due to network shuffling. Therefore, this paper overcomes the limitations of existing systems and proposes more efficient distributed inference methods. It also introduces data partitioning strategies to minimize network shuffling. In addition, it describes a method for optimizing the incremental reasoning process through data selection and determining the rule order. In order to evaluate the proposed methods, the experiments were conducted using WiseKB consisting of 200 million triples with 83 user defined rules and the overall reasoning task was completed in 32.7 minutes. Also, the experiment results using LUBM bench datasets showed that our approach could perform reasoning twice as fast as MapReduce based reasoning systems.

The Analysis of Attributive Level of District Image for City Image - Focus on Busan City - (도시 이미지에 대한 지구 이미지의 기여수준 분석 - 부산시를 중심으로 -)

  • Byeon, Jae-Sang;Choi, Hyung-Seok;Shin, Ji-Hoon;Cho, Ye-Jee;Kim, Song-Yi;Im, Seung-Bin
    • Journal of the Korean Institute of Landscape Architecture
    • /
    • v.35 no.1 s.120
    • /
    • pp.59-68
    • /
    • 2007
  • This article statistically analyzed contributive levels of district image based on an effect and a similarity index through the evaluation of citizens and suggested the efficient management system of a city image according to the results. For this study, Busan City was selected as a case city by the preceding literature and was investigated concerning district image and city image through a questionnaire. The new evaluation method for analysis of a city image was presented in this process. The results of this research are as follows: 1. Busan City has a substantial positive and culturally unique image, and each of its districts have other image characteristics. for example, the CBD district has a positive image, and the sea shore district has a busy and prosperous image, but the backward sea shore district has an image of stagnancy. 2. The image of Yeonje-gu has the largest effect on the image of Busan. Next in influence are Jung-gu, Saha-gu, Suyoung-gu, respectively. The effect index is closely connected with the variance of evaluative adjectives. 3. Busanjin-gu and Haeundae-gu have similar images to Busan City. Next in similarity are Nam-gu, Jung-gu, Youngdo-gu, Suyoung-gu, respectively. The similarity index is closely connected with the correlation of evaluative adjectives. Busan City and its districts can establish their image strategies with the above analyzed results. This study is meaningful in that a statistical evaluative method was proposed. With continued follow-up research, this study may serve as a systematic and logical model to improve the urban landscape and image.

Design and Implementation of Internet Auction Agent System (IAAS) (인터넷 경매 에이전트 시스템(IAAS)의 설계 및 구현)

  • Cho, Kyung-San;Won, You-Seuk
    • The KIPS Transactions:PartD
    • /
    • v.9D no.5
    • /
    • pp.963-970
    • /
    • 2002
  • In this paper, after defining the requirements to improve the processing of Internet auction, we design and implement Internet Auction Agent System (IAAS) based on the requirements. IAAS consists of a multi - agent system with buying/selling/negotiation agents for auction processing in accordance with the given price strategy, a graphic interface for supporting price strategies, an information agent for supplying real time information and remote control of agents, and DB. For the mobility, scalability, functionality and communication efficiency of agents, IAAS is implemented by using Java JDK1.3, Servlet, RMI and socket. Through the comparative analysis, we show that IAAS fulfills the requirements defined. IAAS can improve the convenience of users and the efficiency of auction processing, and thus increase the utilization of Internet auction.

A Study on the Adaptive Reuse Plan for 2013 Suncheon Bay Garden Expo Site (2013순천만국제정원박람회장 활용 계획 연구)

  • Cho, Nam Hun;Choi, Jung-Min
    • Journal of Korean Society of Rural Planning
    • /
    • v.20 no.1
    • /
    • pp.161-173
    • /
    • 2014
  • This study aimed to adaptive reuse plan a take advantage of Suncheon Bay Garden Expo 2013. Detailed objectives included: to identify and foster cultural and ecological resources in Suncheon Bay and Garden Expo Site; and to search and propose characterized program in the site for efficient utilization; and to revitalize a site for the vitalizations of the region where garden culture and garden industries for strengthening local competitiveness. The study was multi-phased. The first stage included basic surveys such as site status and environmental context analysis, and questionnaires and similar case studies, and the second stage was to review the direction of preliminary planning, develop associated industries and strategies for regional revitalization and review and incorporate project details. And the third stage aimed to develop a comprehensive plan from spatial plans and program plans and suggest plans to vitalize the operation of the site. The results of the study are as follows: First, the characterization strategy is 'healing experience tourism', 'healing garden', 'healing herbal care' are suitable for the site and regional revitalization. Second, the dimension of 2013 Suncheon Bay Garden Expo which was distinguished into four areas, in consideration of the characteristics and contents of the garden expo site for efficient operation and maintenance. Four area are as follows: the park oriented area, the experiential tourism oriented area, the existing conservation oriented area, and the area for associated industries. Third, the practice of private and public partnerships is needed in order to efficiently manage and operations. The significance of this study is that it is seeking to take advantage of the Garden Expo site and set the plan by existing resources and in consideration of local characteristics, in conjunction with area to envision and proposed management plan. Some problems are remained which have not been able to deal with details program and organization and financial planning programs for the operation of the site. This is for further study.

The Effects of Well-being Consciousness and Appearance Management of Korean and Japanese Consumers on Attitudes toward Korean Herbal Cosmetics (한국과 일본 소비자의 웰빙의식과 외모관리에 따른 한방화장품 태도 연구)

  • Lee, Yu-Ri;Jung, Hye-Jung
    • Journal of the Korean Society of Costume
    • /
    • v.62 no.2
    • /
    • pp.87-102
    • /
    • 2012
  • The purpose of this study is to identify conceptual constructs of well-being consciousness and appearance management behaviors, and to examine the effects of these two variables on attitudes toward Korean herbal cosmetics for Korean and Japanese consumers. A survey was carried out among female consumers between the ages of 20 and 50, and a total of 500 responses were analyzed by descriptive analysis, reliability test, t-test, and confirmatory factor analysis, structural equation modeling and multi group analysis. The results of this study were as follows: 1) The result of CFA and the reliability test on well-being consciousness and appearance management of Korean and Japanese respondents clearly showed factorial structures on each of the variant assessments. 2) In regards to the well-being consciousness, Korean and Japanese respondents highly tended to perceive well-being as a benefit to the physical health and an eco-friendly lifestyle respectively. In the area of appearance management, Korean and Japanese respondents had similar patterns that showed high scores of skin care and weight control. Both Korean and Japanese consumers showed favorable attitudes toward Korean herbal cosmetic products. 3) The consumers' well-being consciousness revealed to have positive influences on appearance management behavior. Both well-being consciousness and appearance management positively influenced attitudes toward Korean herbal cosmetics. 4) As a result of MGA, the well-being consciousness had more positive impacts on Korean respondents' attitudes toward Korean herbal cosmetics than the appearance management variable when compared to the Japanese respondents. On the other hand, appearance management had more positive impacts on Japanese respondents' attitudes to-ward Korean herbal cosmetics than well-being consciousness when compared to the Korean respondents. These results suggest that differentiated marketing strategies for Korean herbal cosmetics are crucial when targeting Korean and Japanese consumers.

Environmental Knowledge, Eco-Friendly Attitude and Purchase Intention about Eco-Friendly Fashion Products of Fashion Consumers (패션소비자의 환경지식, 친환경 태도가 친환경 패션제품 구매에 미치는 영향)

  • Park, Sung Hee;Oh, Kyung Wha
    • Fashion & Textile Research Journal
    • /
    • v.16 no.1
    • /
    • pp.91-100
    • /
    • 2014
  • The purpose of this study was to examine the effect of consumer's environmental knowledge, eco-friendly attitude and purchase intention about fashion consumers' eco-friendly products. This study was conducted by a survey of 330 males and females fashion consumers in their 20s-40s who experienced eco-friendly fashion products purchase. Respondents, who had purchased eco-friendly fashion items at least once, were selected using convenience sampling through the online survey from March $20^{th}$ to $30^{th}$ in 2013. The collected materials were analyzed by frequency analysis, factor analysis, t-test and multi-regression using SPSS 19.0 software. Through the result of statistical analysis, it is found that environmental knowledge has three dimensions; natural environmental knowledge, urbanized environmental knowledge, environmental pollution knowledge. Also the effects of environmental knowledge on eco-friendly attitude are significant and eco-friendly attitude has influence on eco-friendly fashion products purchase behavior. Eco-friendly attitude had an effect word of mouth intention. In addition, there are notable differences in environmental knowledge, eco-friendly attitude and purchase intention depending on fashion consumer's age. The results of this study will provide useful information for both eco-friendly customer management and fashion marketing strategies. Therefore, the fashion company is needed to consider personal characteristics, customer needs and present condition of purchasing eco-friendly fashion products.