• Biomolecules & Therapeutics
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• 제9권1호
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• pp.63-68
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• 2001

General pharmacological properties of (R)-JG-381 were examined in laboratory animals to investigate its safety profile. Administration of (R)-JG-381 (50 and 100 mg/kg) in mice and rats had no effects of general behaviors, central nervous system of the animals in test systems of pentobarbital-induced sleeping time, writhing syndromes induced by 0.7% acetic acid, chemo-shock produced by pentylenetetrazole, and, however, had mild effects on motor coordination. Heart rate and blood pressure were not changed by (R)-JG-381 treatment. (R)-JG-381 also showed mild effects on intestinal propulsion and gastric secretion. These results suggest that (R)-JG-381 dose not exert serious pharmacological effects.

• Biomolecules & Therapeutics
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• 제10권2호
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• pp.89-98
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• 2002

In this study general pharmacological profiles of KI-60606 on the central nervous system, the cardiovascular system and the other organs were investigated. The dosages given were 0,5, 10 and 25 mg/kg and drugs were administered intravenously. The animals used for this study were mice, rats, cats and guinea pigs. KI-60606 showed no effects on general behavior, motor coordination, spontaneous locomotor activity, hexobarbital-induced hypnosis time, body temperature, analgesic activity, anticonvulsant activity and contraction of nictitating membrane in cats. Furthermore KI-60606 showed no effects on blood pressure, heart rate, LVP (left ventricular peak systolic pressure), LVEDP (left ventricular end diastolic pressure), LVDP (left ventricular developing pressure), DP(double product), CFR(coronary flow rate), smooth muscle contraction using guinea pig ileum and gastric secretion at all dosage tested except the increase of gastrointestinal transport and urinary $K^+$ excretion.

• 한국자동차공학회논문집
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• 제8권6호
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• pp.122-129
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• 2000

This paper describes a hybrid dynamic system(HDS) modeling method and result for the drivertrain of a parallel hybrid electric vehicle(PHEV) which consists of a gasoline engine, an electric machine, and a continuous variable transmission (CVT) and proposes a drivetrain control system. The control system has an engine controller, a motor controller, a CVT controller and a supervisory controller for the coordination of all system. The controller keep the speed of engine wheel and the output torque within the optimal operation range based on the experimental data. We also developed a MATLAB/SIMULINK program for the performance simulation of PHEV drivetrain model and controllers and compared the simulation result with the experiment result in the recent literatures.

• 대한음성학회:학술대회논문집
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• 대한음성학회 2006년도 춘계 학술대회 발표논문집
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• pp.59-62
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• 2006

Young children's speech is compared to adult-to-adult speech and adult-to-child speech by measuring durations and variability of each segment in CVC words. The results demonstrate that child speech exhibits an inconsistent timing relationship between consonants and vowels within a word. In contrast, consonant and vowel durations in adult-to-adult speech and adult-to-child speech exhibit significant relationships across segments, despite variability of segments when speaking rate is decreased. The results suggest that temporal patterns of young children are quite different from those of adults, and provide some evidence for lack of motor control capability and great variance in articulatory coordination.

• Biomolecules & Therapeutics
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• 제7권2호
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• pp.170-177
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• 1999

PEG-hemoglobin SB1 (SB1), which is a hemoglobin-based oxygen carrier, is intended to use as a safe blood substitute against brain ischemia and stroke. The general pharmacological profiles of SB1 were studied. The doses given were 0, 5, 10, 20 ml/kg and drugs were administered intravenously. The animals used for this study were mouse, rat and guinea pig. SB1 showed no effects on general behavior, motor coordination, spontaneous locomotor activity, hexobarbital sleeping time, anticonvulsant activity, analgesic activity, blood pressure and heart rate, left ventricular peak systolic pressure, left ventricular end diastolic pressure, left ventricular developing pressure, double product, heart rate, coronary flow rate, smooth muscle contraction using guinea pig ileum, gastrointestinal transport, gastric secretion, urinary volume and electrolyte excretion at all doses tested except the decrease of body temperature. These findings demonstrated that SB1 possesses no general pharmacological effects at all doses tested.

• 대한한방소아과학회지
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• 제20권2호
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• pp.1-9
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• 2006

Objective : This study was to investigate the effect of oriental medical treatment for Asperger's syndrome. Methods : This patient was lack of social communication, interaction, imagination and motor coordination. It was due to Asperger's syndrome. The patient was treated with Herbal medicine, acupuncture and play therapy. And we evaluated the case with The Australian scale for Asperger's syndrome. Results : Oriental medical treatment and play thrapy alleviated his symptoms of Asperger's syndrome and anxiety. Conclusions : We report the good result of oriental medical treatment on this case. The more study of oriental medical treatment for Asperger's syndrome is needed.

• The Journal of Korean Physical Therapy
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• 제11권3호
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• pp.13-21
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• 1999

Active movement is able to actively contract his muscles and move a segment either with or without assistance. This movement maintain physiologic elasticity and contractility of the participating muscles, provide sensory feedback from the contracting muscles and stimulus for bone integrity as well as increase circulation and prevent thrombus formation, in addition to develop coordination and moor skills for functional activities. Passive movement is the motion to the external force; gravity, machine, another individuals. Active movement is more activated rather than passived on the central nervous system. Therefore, we think that active movement is more effected facilitating through specific inhibitory mobilization of muscle.

• 한국전문물리치료학회지
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• 제8권2호
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• pp.87-94
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• 2001

Dexterity is defined in the present study as interdigital manipulative skill or the fine manipulative movements of objects held between the thumb and fingers. The Grooved pegboard test has been used to evaluate dexterity requring visual-motor coordination. The purpose of this study was to standardize the completion time of the Grooved pegboard test in different age groups and gender. Normative values for the Grooved Pegboard Test was developed on the sample of 282 healthy volunteers (89 men and 183 women). Subjects were stratified according to gender and dominant hand and were subdivided into six groups by blocking. The results of this study were as follows: 1) There was a significant difference in completion time between dominant and nondominant hand in both men and women groups (p<.05). 2) There were significant differences in completion time between men and women group (p<.05) 3) There were significant differences in completion time among age groups (p<.05).

• PNF and Movement
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• 제2권1호
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• pp.35-47
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• 2004

Purpose : The purpose of this article was to review the literature on contractile properties of skeletal muscle with reference to its molecular and functional diversity. Method : This review outlines scientific findings regarding different contractile properties in skeletal muscle fibers, and discusses their involvement in functional diversity. Result & Conclusions: Muscle fibers possess distinct mechanical and energetic properties. Myosis, one of the primary contractile muscle proteins, displays structural, functional variability and plays the role of the molecular motor of muscle contraction. Muscle satellite cells are normally mitotically quiescent, but initiate proliferation and give rise to daughter myogenic precursor cells as required for the postnatal growth and regeneration of adult muscle. Passive extensibility is an important component of total muscle function because it allows for the maximal length of skeletal muscles. Proprioceptive neuromuscular facilitation(PNF) stretching can help to restore or improve flexibility and coordination, thereby improving overall muscle function.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 심포지엄 논문집 정보 및 제어부문
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• pp.77-79
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• 2004

Because robot hardware architecture generally is consisted of a few sensors and motors connected to the central processing unit, this type of structure is led to time consuming and unreliable system. For analysis, one of the fundamental difficulties in real-time system is how to be bounded the time behavior of the system. When a distributed control network controls the robot, with a central computing hub that sets the goals for the robot, processes the sensor information and provides coordination targets for the joints. If the distributed system supposed to be connected to a control network, the joints have their own control processors that act in groups to maintain global stability, while also operating individually to provide local motor control. We try to analyze the architecture of network-based humanoid robot's leg part and deal with its application using the CAN(Controller Area Network) protocol.