• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8659-8663
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• 2016

In Nepal, while no population based cancer registry program exists to assess the incidence, prevalence, morbidity and mortality of cancer, at the national level a number of hospital based cancer registries are cooperating to provide relevant data. Seven major cancer diagnosis and treatment hospitals are involved, including the BP Koirala Memorial Cancer hospital, supported by WHO-Nepal since 2003. The present retrospective analysis of cancer patients of all age groups was conducted to assess the frequencies of different types of cancer presenting from January 1st to December 31st 2012. A total of 7,212 cancer cases were registered, the mean age of the patients being 51.9 years. The most prevalent age group in males was 60-64 yrs (13.6%), while in females it was 50-54 yrs (12.8%). The commonest forms of cancer in males were bronchus and lung (17.6%) followed by stomach (7.3%), larynx (5.2%) and non Hodgkins lymphoma (4.5%). In females, cervix uteri (19.1%) and breast (16.3%), were the top ranking cancer sites followed by bronchus and lung (10.2%), ovary (6.1%) and stomach (3.8%). The present data provide an update of the cancer burden in Nepal and highlight the relatively young age of breast and cervical cancer patients.

• Journal of the Microelectronics and Packaging Society
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• v.22 no.2
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• pp.5-9
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• 2015

Thermal management becomes serious in 3D stacked IC because of higher heat flux, increased power generation, extreme hot spot, etc. In this paper, we reviewed the recent developments of thermal management for 3D stacked IC which is a promising candidate to keep Moore's law continue. According to experimental and numerical simulation results, Cu TSV affected heat dissipation in a thin chip due to its high thermal conductivity and could be used as an efficient heat dissipation path. Other parameters like bumps, gap filling material also had effects on heat transfer between stacked ICs. Thermal aware circuit design was briefly discussed as well.

• BMB Reports
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• v.31 no.5
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• pp.419-426
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• 1998

The nuclear hormone receptor superfamily currently includes approximately equal numbers of conventional receptors and orphan receptors, which do not have known ligands. Here, we review recent progress from this laboratory on three orphans, two of which are moving from orphan to conventional receptor status. Perhaps the most unusual is CAR, which is a constitutive transactivator in the absence of ligands but becomes transcriptionally inactive in the presence of its ligands, which are androgen metabolites. The response of CAR to its ligands is thus opposite to that of the conventional receptor paradigm. RIP14 (also known as FXR) is activated by both all-trans retinoic acid and a synthetic retinoid previously thought to specifically target the retinoic acid receptors (RARs), and thus appears to be a novel retinoid receptor. Finally, SHP is a novel orphan that lacks a DNA binding domain and interacts with a number of other receptor superfamily members. While it generally inhibits its targets, including CAR, the retinoid X receptor (RXR), and the estrogen receptor (ER), it stimulates transactivation by the orphan SF-1.

• Information Systems Review
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• v.15 no.1
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• pp.25-43
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• 2013

The Korean Smartphone industry has advanced rapidly. There seems to have a considerable change in Korea smartphone industry as the security policy related to wireless devices is changed from Whitelist Policy to Blacklist Policy. In regard to such a change, this paper analyzes the smartphone market in terms of the Business Ecosystem Model suggested by Moore. This study examines how Korean Smartphone Ecosystem has been formed and how any shifts in policy will have an effect on the ecosystem. In line with this policy shift, this study also suggests the ways how these ecosystem members should establish a strategy for the continuous development of this smartphone ecosystem. Furthermore, this study presents cooperation directions among ecosystem members based on the organic connections in the ecosystem as well as each individual's corresponding measures. In addition, based on this analysis, this study puts forward Korean smartphone ecosystem's current problems, improvement, and its future.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1589-1593
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• 2016

Opisthorchis viverrini (OV) liver flukes are common parasites found in central and southern Laos and constitute a major public health problem in the country. Laos people continue to have the habit of extensively consuming raw or half-cooked fish which are intermediate hosts. This study aimed to determine the prevalence and factors associated with OV infection in the population of Thakek district, Khammouane Province. This cross-sectional analytic study covered 237 subjects who filled out structured questionnaires. Fecal examination for OV infection was performed by Kato's thick smear method. Data analysis was carried out using STATA Version 10.0. Multiple logistic regression was applied. The results showed that the infection rate of OV was 54.8%. Factors associated with OV infections were gender, a habit of defecation in fields and raw fish (goi bplaa dip) consumption. Opisthorchiasis and associated cholangiocarcinoma development thus appear to remain as important concerns in Laos.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.7033-7037
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• 2013

The purpose of the present study was to provide an assessment of the incidence of cancer of the larynx in Kazakhstan with especial attention to ethnicity and gender, as well as age. The retrospective design covered all new cases of laryngeal cancer in 11 years (1999-2009). The total number was 4,967 cases, 4,535 (91.3%) in males and 432 (8.7%) in women, with a gender ratio of 10.5:1. Patients of Kazakh (31.2%) and Russian (51.4%) ethnicity accounted for the vast majority (82.6%), with Russians predominating in both sexes, but particularly in females. Age peak in Kazakhs was 70 years and older ($14.6{\pm}0.70/0000$), and in Russians was 60-69 years ($21.6{\pm}1.30/0000$). In the dynamics, the rates had the tendency to decrease more markedly in Russian than Kazakh men, especially in the younger groups, while increase was noted in the youngest females of both ethnicities, but again greater in Russians, presumably reflecting change in underlying lifestyle factors.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4181-4186
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• 2013

In the article were observed the epidemiological aspects of malignant tumors of the central nervous system (MT CNS) in Kazakhstan in a retrospective study for the years 2004-2011. The material of the study was consolidated accounting data of oncology centers on patients with MT CNS (C70-72) with first time established diagnosis. Calculated were crude, age, standardized (world standard), aligned and predicted incidence of MT CNS among both male and female populations. It was found that over the studied period, there were 4,604 cases of MT CNS. The average annual crude incidence rate of MT CNS in total population was $3.7{\pm}0.1^0/_{0000}$. Trends in aligned incidence rates in the whole country had a tendency to increase (T=+0.9%). Defined levels of morbidity MT CNS in the whole population in different regions of Kazakhstan: low up to $2.87^0/_{0000}$, the average from 2.87 to $4.45^0/_{0000}$ and high from $4.45^0/_{0000}$ and above on the basis of which was given the space-time estimate. Age and sex differences in MT CNS incidence were also clearly established.

• Journal of Integrative Natural Science
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• v.11 no.3
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• pp.131-138
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• 2018

In this paper, we have implemented speeches that utilized the emotion information of the user's speech and image matching and recommendation system. To classify the user's emotional information of speech, the emotional information of speech about the user's speech is extracted and classified using the PLP algorithm. After classification, an emotional DB of speech is constructed. Moreover, emotional color and emotional vocabulary through factor analysis are matched to one space in order to classify emotional information of image. And a standardized image recommendation system based on the matching of each keyword with the BM-GA algorithm for the data of the emotional information of speech and emotional information of image according to the more appropriate emotional information of speech of the user. As a result of the performance evaluation, recognition rate of standardized vocabulary in four stages according to speech was 80.48% on average and system user satisfaction was 82.4%. Therefore, it is expected that the classification of images according to the user's speech information will be helpful for the study of emotional exchange between the user and the computer.

• Journal of architectural history
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• v.19 no.4
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• pp.91-108
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• 2010

The objective of this paper is to clarify the architectural characteristics of the Korean-Western eclectic houses at Ojeong-dong Missionary Village in Daejeon city, focused on the spatial and structural changes due to eclecticism. The consequences of the comparative analysis between the eclectic houses and two reference buildings, Myeongjae residence and Moore house, are as follows. The diverse aspects due to eclecticism can be summarized as two concepts; transformation and simplification. The transformation has appeared in the characteristic spatial elements such as an-madang, entrance and corridor, in the territory organization and the connection between building and yard, and in the roof and wall structures. The simplification has appeared in the layering of the building space, and in the joint of roof and wall. The methods of eclecticism and the resultant aspects from them that are clarified through this study are expected to be referred in examining the new possibilities of the hanok.

• Korean Institute of Interior Design Journal
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• no.33
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• pp.27-35
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• 2002

The qualify of preschool education is related to the qualify of the physical environment, This research is aiming to develop and validate the set of scales for the measurement of physical quality of the interior spaces in child care facilities. The research has been in three major phases: (1)the development of indicative sub-scales for the description, measurement and evaluation of the physical designed quality of early childhood environments (2)two rounds of iterative phases of reliability and validity testing of the scales through expert panels and observational field-testing and (3)implications for future research to be done. 13 sub-scales were developed, which are based on Moore's 15 design principal for child care environments. And each sub-scale includes several evaluation items based upon developmental theory, existing empirical literature, and Korean, Australian and American child care standards. This set of scales will (1)aid research on the effects of environmental variables on quality of child care facilities for infants, toddlers, and preschoolers; (2)permit evaluation of such environments to identify areas of needed improvement; and (3)provide information for policy makers, parents, administrators, and designers/architects.