• Title/Summary/Keyword: Mononuclear

Search Result 554, Processing Time 0.027 seconds

Clinical utilization of cord blood over human health: experience of stem cell transplantation and cell therapy using cord blood in Korea

  • Lee, Young-Ho
    • Clinical and Experimental Pediatrics
    • /
    • v.57 no.3
    • /
    • pp.110-116
    • /
    • 2014
  • Cord blood (CB) has been used as an important and ethical source for hematopoietic stem cell transplantation (SCT) as well as cell therapy by manufacturing mesenchymal stem cell, induced pleuripotential stem cell or just isolating mononuclear cell from CB. Recently, the application of cell-based therapy using CB has expanded its clinical utility, particularly, by using autologous CB in children with refractory diseases. For these purposes, CB has been stored worldwide since mid-1990. In this review, I would like to briefly present the historical development of clinical uses of CB in the fields of SCT and cell therapy, particularly to review the experiences in Korea. Furthermore, I would touch the recent banking status of CB.

A Study on the Tungsten (VI) Complexes with the Organic Acid Anhydrides (유기산 무수물을 리간드로한 텅스텐 (VI) 착물에 관한 연구)

  • Sang-Oh Oh;Kim, Chan Ho
    • Journal of the Korean Chemical Society
    • /
    • v.19 no.6
    • /
    • pp.408-413
    • /
    • 1975
  • Dichloro-dioxo-tungsten(VI) complexes containing oxygen donor in anhydrous organic acid have been synthesized. Sodium tungstate reacts with acetylchlorides to produce the mononuclear complexes, yellow powder having $WO_2Cl_2(RCO)_2O$ as general formula. Their chemical properties and the possible structure are proposed by the results of spectral data and chemical observation.

  • PDF

A STUDY OF THE MALIGNANT FIBROUS HISTIOCYTOMA (악성 섬유성 조직구종에 관한 연구)

  • Kim Young-Jin;Oh Phill-Gyo;Choi Eui-Hwan
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
    • /
    • v.24 no.2
    • /
    • pp.451-457
    • /
    • 1994
  • Malignant fibrous histiocytoma(MFH) is relatively rare in the oro-maxillofacial region, particularly in the oral cavity. MFH usually arise in the extremities, the thigh being the most common site. The incidence of malignant fibrous histiocytoma in bones is rather low compared with that in soft tissues. MFH is predominant in the 40s and 50s. Histologically, the lesion are said to show high cellularity with fibrous stroma, cellular and nuclear pleomorphism, an admixture of fibroblast-like spindle cells which tend to be arranged in whorls or cartwheel or storiform patterns, rounded mononuclear cells and multinucleated giant cells. The cells frequently have abundant eosinophilic cytoplasm which has a foamy or vesicular appearance. Treatment consists of varying combinations of radiation therapy, chemotherapy, and surgery. We have observed a case of malignant fibrous histiocytoma occured in the right maxilla of 32-year-old woman.

  • PDF

Degenerative joint disease with systemic mycoses in a oriental white stork

  • Lee, Sook-Jin;Han, Je-Ik;Chang, Dong-Woo;Na, Ki-Jeong
    • Korean Journal of Veterinary Research
    • /
    • v.47 no.1
    • /
    • pp.95-98
    • /
    • 2007
  • Rehabilitation Research was presented to Veterinary Medical Center of Chungbuk National Universitywith anorexia and lameness for 5 days. Bilateral intertarsal joint swellings were observed in physicalexamination. The radiographic findings indicated degenerative changes of joint cartilage and suroundingbones. In cytologic examination of synovial fluids, mononuclear leukocytic inflammation was identified.on Sabroud dextrose agar. From all of examinations, this patient was diagnosed as a degenerative jointdisease with systemic mycoses.

Outbreak of Leucocytozoonosis in Chickens (닭 Leucocytozoon병(病)의 집단발생(集團發生)과 병리학적(病理學的) 관찰(觀察))

  • Kwak, Soo-Dong;Jyeong, Jong-Sik
    • Korean Journal of Veterinary Research
    • /
    • v.23 no.2
    • /
    • pp.183-186
    • /
    • 1983
  • The clinical and histopathological observation of leucocytozoonosis was carried out during July, 1982 at a poultry compound in Gyeongbuk province and the results were summarized as follows: 1. Leucocytozoonosis was observed in 36,900 of 59,900 chickens (61.6%) and the mortality rate was 18.3% (6,760 of 36,900 chickens infected). 2. Clinical findings were anorexia, dyspnea, paleness of comb, greenish diarrhea and reduction of egg production. 3. Gross lesions were yellowish white spots scattered on parenchymal organs and swelling of liver and spleen. In addition, petechiation and ecchymosis of small intestine, egg yolk and subcutaneous tissues were observed. 4. Histological findings were infiltration of mononuclear cells in liver, heart and lung, appearance of megaloschizonts in heart, liver, proventriculus and pancreas, proliferation of foreign body giant cells in heart, and hyperemia and swelling of all parenchymal organs.

  • PDF

A New Chemosensing Ensemble for Colorimetric Detection of Oxalate in Water

  • Tang, Li-Jun;Liu, Ming-Hui
    • Bulletin of the Korean Chemical Society
    • /
    • v.31 no.11
    • /
    • pp.3159-3162
    • /
    • 2010
  • To realize highly selective recognition of oxalate in water, a new chemosensing ensemble that behaves highly selective colorimetric recognition of oxalate in water at pH 7.4 has been developed. The ensemble was constructed by a pyrrole containing mononuclear copper complex and chromeazurol S. The ensemble shows a highly selective recognition of oxalate through an obvious color change from blue to yellow upon the addition of oxalate, whereas, other dicarboxylates such as malonate, succinate, fumarate, maleate, glutarate, adipate, phthalate, isophthalate and terephthalate do not induce any noticeable color changes. The oxalate recognition process is not significantly affected by other coexisting dicarboxylate.

A Case of Canine Hydrocephalus with Nonsuppurative Encephalitis (비화농성 뇌염을 동반한 개 수두증 1례)

  • 한정희;서강문
    • Journal of Veterinary Clinics
    • /
    • v.17 no.2
    • /
    • pp.470-474
    • /
    • 2000
  • A Shih Tzu Puppy had clinical onset of anotexia crying and progression of neurological sings when enlargement of the cranial vault at 1 month old and died after showing clinical signs during 2 months period. Radiological and pathological examinations were performed. Radiological findings were homogeneous appearance of the calvaria with cortical thinning, loss of the normal convolutional skull markings and persistent fontanelles. Grossly enlargement of the cranial vault thinning of the bone and defective closure of the fontanelles were also observed. The entire subcortical area of the cerebral hemispheres with severe, dilatation of ventricles and cerebrospinal fluid(CSF) wits absent. There was parenchyma atrophy affecting chiefly in the white mater and the cerebral cortices, axon degeneration and necrosis and gitter cell infiltration in the whiter matter and the subependymal area. Mononuclear perivacular cuffing in the cerebrum and the pons was shown. Based on the radiological, gross and histopathological findings, this case was believed to have congenital hydrocephalus with nonsuppurative encephahitis. Possible etiology on the case is also discussed.

  • PDF

Peripheral Giant Cell Granuloma in a Dog (개의 말초성 거대세포 육아종(peripheral giant cell granuloma) 증례 보고)

  • Cho, Ho-Seong;Cho, Kyoung-Oh;Park, Nam-Yong
    • Korean Journal of Veterinary Pathology
    • /
    • v.5 no.2
    • /
    • pp.79-80
    • /
    • 2001
  • A gingival mass was detected from a 1-year-old female Great Dane dog. After surgical removal, the lesions recurred in 2 weeks and died of septicemia. Characteristic histologic features were large numbers of multinucleated giant cells which were connected with capillary vessels. Neovascularization was prominent with mononuclear and polynuclear cell infiltration. Overall features of these lesions except for giant cell infiltration were similar to granuloma. From these results, a gingival mass excised from a dog was diagnosed to be a peripheral giant cell granuloma (PGCG). This is the first report of canine subcutaneous PGCG in Korea.

  • PDF

Template Synthesis, Crystal Structure, and Magnetic Properties of a Dinuclear Copper(II) Complex with Cooperative Hydrogen Bonding

  • Kang, Shin-Geol;Nam, Kwang-Hee;Min, Kil-Sik;Lee, Uk
    • Bulletin of the Korean Chemical Society
    • /
    • v.32 no.3
    • /
    • pp.1037-1040
    • /
    • 2011
  • The dinuclear complex 1 with cooperative hydrogen bonds can be prepared by the metal-directed reaction of Eq. (2). This work shows that the coordinated hydroxyl group trans to the secondary amino group is deprotonated more readily than that trans to the tertiary amino group and acts as the hydrogen-bond accepter. The lattice water molecules in 1 act as bridges between the two mononuclear units through hydrogen bonds. The complex is quite stable as the dimeric form even in various polar solvents. The complex exhibits a weak antiferromagnetic interaction between the metal ions in spite of relatively long Cu$\cdots$Cu distance. This strongly supports the suggestion that the antiferromagnetic behavior is closely related to the cooperative hydrogen bonds.

Study on respiratory disorders in slaughtered pigs (도축돈의 호흡기질병에 관한 연구)

  • 이청산;김원설;손현수;이은정;박경재
    • Korean Journal of Veterinary Service
    • /
    • v.23 no.3
    • /
    • pp.255-262
    • /
    • 2000
  • A survey on pneumonic lungs and its histopathological changes of the slaughtered pigs from the southern area of Chungbuk province was carried out during the period from January to December 1999. Pneumonic lungs were attempted bactenological findings and antibiotic susceptibilities. The results obtained were as follows; 1. Of 158 slaughtered pigs, 97(61.4%) pigs had pneumonic lesions in the lung, and the prevalence was high in winter, spring, autumn, and summer in order. f. The bacteria isolated from pneumonic lesions were pasteurella spp, 13 heads(34.2%), streptococcus spp, 6(IS.8%), actinobacillus spp, 3(7.9%), coliform 4(10.5%) and the other bacteria, 12(31.6%). 3. These isolates were highly susceptible to the antibiotics of enrofloxacin 30(78.9%), cephalothin 23(73.6%) and ceftiofur 27(71 %). 4. Histopathologically, swine enzootic pneumonia and pleuropneumonia lesions were observed. The swine enzootic pneumonia lesions were consisted of peribronchiolar lymphoid hyperplasia and exudate in alveolar lumen. The pleuropneumonia lesions were consisted of thrombosis, alveolar wall thickened by mononuclear cells and neutrophil deposition.

  • PDF