• Title/Summary/Keyword: Mongolia

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Rapamycin Inhibits Expression of Elongation of Very-long-chain Fatty Acids 1 and Synthesis of Docosahexaenoic Acid in Bovine Mammary Epithelial Cells

  • Guo, Zhixin;Wang, Yanfeng;Feng, Xue;Bao, Chaogetu;He, Qiburi;Bao, Lili;Hao, Huifang;Wang, Zhigang
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.11
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    • pp.1646-1652
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    • 2016
  • Mammalian target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth and metabolism and is sufficient to induce specific metabolic processes, including de novo lipid biosynthesis. Elongation of very-long-chain fatty acids 1 (ELOVL1) is a ubiquitously expressed gene and the product of which was thought to be associated with elongation of carbon (C) chain in fatty acids. In the present study, we examined the effects of rapamycin, a specific inhibitor of mTORC1, on ELOVL1 expression and docosahexaenoic acid (DHA, C22:6 n-3) synthesis in bovine mammary epithelial cells (BMECs). We found that rapamycin decreased the relative abundance of ELOVL1 mRNA, ELOVL1 expression and the level of DHA in a time-dependent manner. These data indicate that ELOVL1 expression and DHA synthesis are regulated by mTORC1 in BMECs.

Effects of the Substitution of Mischmetal for PrNd on the Microstructures and Magnetic Properties of Rapidly Quenched (MM)PrNd-Fe-B Nanocrystalline Magnets

  • Zhao, Zeng-ru;Wang, Xin;Zhang, Xue-feng;Ma, Qiang;Liu, Yan-li;Li, Yong-feng;Liu, Fei;Wang, Gao-feng
    • Journal of Magnetics
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    • v.22 no.1
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    • pp.60-64
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    • 2017
  • Mischmetal of Bayan Obo ore was utilized to prepare the high performance $(Pr_{7.34}Nd_{21.86})_{1-x}MM_xFe_{68.7}Al_{0.1}Cu_{0.12}Co_{0.88}B$ ribbons using melt-spinning method. Phase composition and magnetic properties were investigated at room temperature. The ribbons mainly consist of $R_2Fe_{14}B$ phase in isotropic nanostructure. Both coercivity and maximum energy product decrease with the increase of MM content. The magnetic parameters of the ribbons with MM = 20 % in mass are $B_r=7.38kGs$, $H_{cj}=13.66kOe$, $(BH)_{max}=11.81MGOe$. Henkel plots were applied to demonstrate the exchange coupling interaction between grains.

International Multimodal Transport Route Development from Korea to Mongolia

  • Nyamjav, Tsenskhuu;Ha, Min-Ho
    • Journal of Navigation and Port Research
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    • v.46 no.5
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    • pp.419-426
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    • 2022
  • This study aimed to identify new routes for transporting automobiles from Korea to Mongolia by comparing them with the existing route. At present, a route from the Incheon Port through the Tianjin Port to Zamiin-Uud is commonly used to transport containerized cargo from Korea to Mongolia. This study examined five possible logistics routes from Korea to Mongolia using a time/cost-distance methodology based on real data. Through consecutive discussions with importers and freight forwarders in Mongolia, the potential routes were selected and costs, distance, and lead time were evaluated to provide additional route options for automobile logistics from Korea to Mongolia. The results indicated that each route could be ranked in terms of the total cost while the lead time for all options in the present COVID-19 period is 2 - 4 months, with no difference among the routes. In addition, although the confidence index of all routes was not impressive, route 3 was the most preferred option, followed by route 1. However, the study results cannot provide the answer to the question of "which route is more attractive for transporting automobiles from Korea to Mongolia." This limitation notwithstanding, this study provides real information on the critical factors of distance, cost, and lead time in terms of the selected transportation routes so that importers and exporters can compare the routes in terms of the priority of each factor in uncertain logistics environment.

Molecular Characterization and Expression Pattern of Gene IGFBP-5 in the Cashmere Goat (Capra hircus)

  • Wang, X.J.;Shi, J.J.;Yang, J.F.;Liang, Y.;Wang, Y.F.;Wu, M.L.;Li, S.Y.;Guo, X.D.;Wang, Z.G.;Liu, D.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.5
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    • pp.606-612
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    • 2012
  • Insulin-like growth factor-binding protein-5 (IGFBP-5) is one of the six members of IGFBP family, important for cell growth, apoptosis and other IGF-stimulated signaling pathways. In order to explore the significance of IGFBP-5 in cells of the Inner Mongolian Cashmere goat (Capra hircus), IGFBP-5 gene complementary DNA (cDNA) was amplified by reverse transcription polymerase chain reaction (RT-PCR) from the animal's fetal fibroblasts and tissue-specific expression analysis was performed by semi-quantitative RT-PCR. The gene is 816 base pairs (bp) in length and includes the complete open reading frame, encoding 271 amino acids (GenBank accession number JF720883). The full cDNA nucleotide sequence has a 99% identity with sheep, 98% with cattle and 95% with human. The amino acids sequence shares identity with 99%, 99% and 99%, respectively. The bioinformatics analysis showed that IGFBP-5 has an insulin growth factor-binding protein homologues (IB) domain and a thyroglobulin type-1 (TY) domain, four protein kinase C phosphorylation sites, five casein kinase II phosphorylation sites, three prenyl group binding sites (CaaX box). The IGFBP-5 gene was expressed in all the tested tissues including testis, brain, liver, lung, mammary gland, spleen, and kidney, suggesting that IGFBP-5 plays an important role in goat cells.

Soil and Coal Radioactivity around Zuunmod Town of Mongolia

  • Erkhembayar, Ts.;Norov, N.;Khuukhenkhuu, G.;Oyunchimeg, Ts.
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.501-505
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    • 2002
  • The specific radioactivity concentrations of $\^$238/U, $\^$232/Th, $\^$40/K were measured in soil samples around Zuunmod town of Mongolia using HP-Ge gamma-spectrometer. Also the specific radioactivity concentrations of above elements were measured in coal and ash samples which were collected from the Central steam heating in Zuunmod town. It was determined the effective equivalent dose.

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The 2004 parliamentary election in Mongolia: Big surprises and small victories

  • Schafferer, Christian
    • Journal of Contemporary Eastern Asia
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    • v.3 no.2
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    • pp.1-6
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    • 2004
  • On 27 June 2004, some one million voters went to the polls in Mongolia to elect 76 members of the Great State Hural, Mongolia's parliament. It was the fourth election held in Mongolia under the 1992 constitution. In the previous election, the former communist MPRP won a landslide, ousting the government of former democracy activists. Under the MPRP, Mongolia's economy performed extraordinary well. Surprisingly, the ruling Mongolian People's Revolutionary Party (MPRP) lost its two-thirds majority and half its parliamentarians in the 2004 election. But the Motherland Democracy Coalition (MDC), a coalition of Mongolia's most influential opposition parties, fell short of achieving a majority of its own. After the election, a grand coalition government was formed, paving the way for profound legal, social, and economic reforms.

The Relationship Between Financial Condition and Business Cycle in Mongolia

  • Doojav, Gan-Ochir;Purevdorj, Munkhbayar
    • East Asian Economic Review
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    • v.23 no.2
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    • pp.203-223
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    • 2019
  • This paper examines the interactions between financial conditions and business cycles in Mongolia, a small open economy, heavily depending on commodity exports. We construct two financial conditions indexes based on the reduced form IS model and the vector autoregression (VAR) model as surveillance tools to quantify the degree of the financial conditions. We find that real short-term interest rate and real effective exchange rate gap get a higher weight in the FCIs. Both business and financial cycles are often more pronounced in Mongolia, and financial condition is dependent of the financial and monetary policies in place. The analysis of the predictive power of the FCIs for business cycles shows that they have predictive information for the near-term economic activities. FCIs are also helpful in signaling inflation turning points.

Integrated Development Planning for the Mongolian Economic Development Planning

  • Park, Myungho
    • Journal of Appropriate Technology
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    • v.6 no.1
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    • pp.65-78
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    • 2020
  • This paper deals with challenges of Mongolian government regarding Economic Development Plan (hereafter EDP). EDP has a long history, appearing first in the socialist countries, then in European countries following the European Reconstruction Plan after the Second World War, and then in many developing countries after they gained independence from the colonial rule. Major challenges of the Mongolian EDP are largely related to the absence or lack of integrated approach. We will propose a new integrated framework based on the approach suggested by UNDP. The new framework consists of 5 core areas; 1) institutions and governance, 2) evidence-based and empirically backed policy options, 3) development of budgeting and financial system, 4) and monitoring and evaluation (M&E), 5) capacity development. In order to identify challenges in Mongolia, the new integrated approach was applied to diagnose current states. To understand current states of EDP in Mongolia, survey regarding EDP in Mongolia was conducted for the 43 officials of Ministry of Finance. The same approach was applied for Five-Year Economic Development Plans in Korea to compare performances with EDP in Mongolia. On the basis of comparative analysis of EDPs in Mongolia and Korea, some lessons are suggested.

Dexamethasone enhances glucose uptake by SGLT1 and GLUT1 and boosts ATP generation through the PPP-TCA cycle in bovine neutrophils

  • Wang, Xinbo;Tang, Mingyu;Zhang, Yuming;Li, Yansong;Mao, Jingdong;Deng, Qinghua;Li, Shusen;Jia, Zhenwei;Du, Liyin
    • Journal of Veterinary Science
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    • v.23 no.5
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    • pp.76.1-76.14
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    • 2022
  • Background: Clinical dexamethasone (DEX) treatment or stress in bovines results in extensive physiological changes with prominent hyperglycemia and neutrophils dysfunction. Objectives: To elucidate the effects of DEX treatment in vivo on cellular energy status and the underlying mechanism in circulating neutrophils. Methods: We selected eight-month-old male bovines and injected DEX for 3 consecutive days (1 time/d). The levels of glucose, total protein (TP), total cholesterol (TC), and the proinflammatory cytokines interleukin (IL)-1β, IL-6 and tumor necrosis factor (TNF)-α in blood were examined, and we then detected glycogen and adenosine triphosphate (ATP) content, phosphofructosekinase-1 (PFK1) and glucose-6-phosphate dehydrogenase (G6PDH) activity, glucose transporter (GLUT)1, GLUT4, sodium/glucose cotransporter (SGLT)1 and citrate synthase (CS) protein expression and autophagy levels in circulating neutrophils. Results: DEX injection markedly increased blood glucose, TP and TC levels, the Ca2+/P5+ ratio and the neutrophil/lymphocyte ratio and significantly decreased blood IL-1β, IL-6 and TNF-α levels. Particularly in neutrophils, DEX injection inhibited p65-NFκB activation and elevated glycogen and ATP contents and SGLT1, GLUT1 and GR expression while inhibiting PFK1 activity, enhancing G6PDH activity and CS expression and lowering cell autophagy levels. Conclusions: DEX induced neutrophils glucose uptake by enhancing SGLT1 and GLUT1 expression and the transformation of energy metabolism from glycolysis to pentose phosphate pathway (PPP)-tricarboxylic acid (TCA) cycle. This finding gives us a new perspective on deeper understanding of clinical anti-inflammatory effects of DEX on bovine.

Korean Firms' Entry Strategy in Mongolia (한국 기업들의 몽골 시장 진출 전략)

  • Kim, Jai-Rim;Seo, Jeongil;Chung, Sun-Wook
    • Asia-Pacific Journal of Business
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    • v.12 no.4
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    • pp.107-134
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    • 2021
  • Purpose - Korean firms have entered the Mongolia, the world's top 10 resource rich country with huge market potential, since the diplomatic relations between Korea and Mongolia were established in 1990, but little is known about Korean firms' entry strategy in the Mongolian market. With this background, this study aims to investigate the seven cases of Korean firms doing business in Mongolia (SK Telecom, Samsung S1, T-Money, E1 Energy, Cafe Bene, E-Mart, and CU). Methodology - this study is based on numerous primary and secondary data about the Mongolian market, as well as Korean firms in Mongolia. Findings - the following three implications were derived from our case analysis: first, when entering into Mongolia, a thorough analysis of political and social risks and a good understanding of institutional voids should be preceded. Second, for this reason, entering through cooperation with local partners, such as joint ventures or franchising, is expected to increase the possibility of success. Third, unlike in the early days of Korean firms in Mongolia, the business environment in Mongolia has become more stable and predictable, and a friendly atmosphere for Koreans and Korean firms is forming, increasing the possibility of success and settlement of Korean firms. Research implications - this study contributes to extant literature by providing more systematic research on Korean firms in Mongolia and by presenting practical implications through the analysis of success and failure cases of Korean firms in the Mongolian market.