• 한국기계가공학회지
• /
• 제18권12호
• /
• pp.7-14
• /
• 2019

A marine turning gear controls the position of the piston-crank mechanism by rotating the flywheel of the marine engine at a low speed, which is the main auxiliary machine that enables the disassembly and maintenance of the engine. In this study, the safety factor for surface durability and tooth bending strength was improved by the design modification of the marine turning gear based on the spur planetary gear. Angular velocity, torque, and efficiency of the turning gear were measured using a reliability evaluation tester, and a multibody dynamics model for analysis corresponding to the test results was developed. Finally, it was confirmed that the design improvements improved the tooth surface damage of the sun gear in the 3^rd reduction stage.

• 한국의류학회지
• /
• 제27권9_10호
• /
• pp.1101-1111
• /
• 2003

The objectives of this study were to classify the contents of lifestyle of adolescents, to investigate the relationships between lifestyles and appearance behavior, and to examine how appearance behavior was influenced by lifestyles and demographic variables of male and female adolescents. The method of the study was survey research by using questionnaires. Subjects were 414 high school students in Seoul: 176 were males and 238 females. Five dimensions of lifestyles were derived by factor analysis: ‘digital orientation', 'positive activity', 'achievement orientation', 'material orientation', and ‘frugality'. Digital orientation had, in case of the male, a positive relation with body-modification need, a positive one with appearance interest in female. Positive activity had positive relations with appearance interest and body satisfaction in both male and female. Appearance interest, weight interest, and body-modification need levels were significantly higher for female than for male, whereas body satisfaction were higher for male than for female. Appearance interest of male was influenced by positive activities and social stratification. Appearance interest of female was influenced by material orientation and positive activity. Body-modification need of male was influenced by digital orientation and frugality(-), that of female only influenced by material orientation. Fashion and brand preference of male was influenced by material orientation, frugality(-), and social stratification. In case of the female, fashion was influenced by positive activity, material orientation and frugality(-), brand preference influenced by material orientation and positive activity.

• Structural Engineering and Mechanics
• /
• 제10권4호
• /
• pp.405-426
• /
• 2000

Two approximate methods based on mechanism analysis suitable for seismic assessment/design of structural concrete are reviewed. The methods involve use of equal energy concept or equal displacement concept along with appropriate patterns of inelastic deformations to relate structure's maximum lateral displacement to member and plastic deformations. One of these methods (Clough's method), defined here as a ductility-based approach, is examined in detail and a modification for its improvement is suggested. The modification is based on estimation of maximum inelastic displacement using inelastic design response spectra (IDRS) as an alternative to using equal energy concept. The IDRS for demand displacement ductilities are developed for a single degree of freedom model subjected to several accelerograms as functions of response modification factor (R), damping ratios, and strain hardening. The suggested revised methodology involves estimation of R as the ratio of elastic strength demand to code level demand, and determination of design base shear using $R_{design}{\leq}R$ and maximum displacement, determination of plastic displacement using IDRS and subsequent local plastic deformations. The methodology is demonstrated for the case of a 10-story precast wall panel building.

• Molecules and Cells
• /
• 제45권7호
• /
• pp.435-443
• /
• 2022

In response to environmental changes, signaling pathways rewire gene expression programs through transcription factors. Epigenetic modification of the transcribed RNA can be another layer of gene expression regulation. N⁶-adenosine methylation (m⁶A) is one of the most common modifications on mRNA. It is a reversible chemical mark catalyzed by the enzymes that deposit and remove methyl groups. m⁶A recruits effector proteins that determine the fate of mRNAs through changes in splicing, cellular localization, stability, and translation efficiency. Emerging evidence shows that key signal transduction pathways including TGFβ (transforming growth factor-β), ERK (extracellular signal-regulated kinase), and mTORC1 (mechanistic target of rapamycin complex 1) regulate downstream gene expression through m⁶A processing. Conversely, m⁶A can modulate the activity of signal transduction networks via m⁶A modification of signaling pathway genes or by acting as a ligand for receptors. In this review, we discuss the current understanding of the crosstalk between m⁶A and signaling pathways and its implication for biological systems.

• 멤브레인
• /
• 제33권1호
• /
• pp.1-12
• /
• 2023

본 총설은 소수성 불소수지계 분리막의 표면 개질에 대한 개론으로 다양한 표면 개질 방법 및 그 연구 결과를 중점적으로 서술하였다. PTFE로 대표되는 불소수지계 고분자 분리막은 막 증류, 유수 분리, 기체 분리를 포함한 다양한 막 분리 공정에서 사용되어왔다. PTFE 막은 내화학성, 내열성, 높은 기계적 강도와 같은 뛰어난 물성에도 불구하고 소수성 표면 특성으로 인해 기술 적용의 확장에 제한적이다. 친수성 향상을 위해 습식 화학법, 친수성 고분자 코팅, 플라즈마 처리, 조사, 원자층 증착과 같은 다양한 PTFE 표면 개질 방법을 이용하며 이를 통해 불소수지계 분리막의 응용분야가 확장될 수 있다.

• Journal of Mechanical Science and Technology
• /
• 제17권3호
• /
• pp.343-349
• /
• 2003

The fuselage-wing intersection suffers from the cyclic bending moment of variable amplitude. Therefore, the influence of cyclic bending moment on the delamination and the fatigue crack propagation behavior in AFRP/Al laminate of fuselage-wing was investigated in this study. The cyclic bending moment fatigue test in AFRP/Al laminate was performed with five levels of bending moment. The shape and size of the delamination Lone formed along the fatigue crack between aluminum sheet and aramid fiber-adhesive layer were measured by an ultrasonic C-scan. The relationships between da/dN and ΔK, between the cyclic bending moment and the delamination zone size, and between the fiber bridging behavior and the delamination zone were studied. As results, fiber failures were not observed in the delamination zone in this study, the fiber bridging modification factor increases and the fatigue crack growth rate decrease and the shape of delamination zone is semi-elliptic with the contour decreasing non-linearly toward the crack tip.

• BMB Reports
• /
• 제40권5호
• /
• pp.684-689
• /
• 2007

The endogenous neurotoxin, 1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (salsolinol), has been considered a potential causative factor for the pathogenesis of Parkinson's disease (PD). In the present study, we examined the pattern of human Cu,Zn-superoxide dismutase (SOD) modification elicited by salsolinol. When Cu,Zn-SOD was incubated with salsolinol, some protein fragmentation and some higher molecular weight aggregates were occurred. Salsolinol led to inactivation of Cu,Zn-SOD in a concentration-dependent manner. Free radical scavengers and catalase inhibited the salsolinol-mediated Cu,Zn-SOD modificaiton. Exposure of Cu,Zn-SOD to salsolinol led also to the generation of protein carbonyl compounds. The deoxyribose assay showed that hydroxyl radicals were generated during the oxidation of salsolinol in the presence of Cu,Zn-SOD. Therefore, the results indicate that free radical may play a role in the modification and inactivation of Cu,Zn-SOD by salsolinol.

• 한국소음진동공학회:학술대회논문집
• /
• 한국소음진동공학회 2002년도 추계학술대회논문집
• /
• pp.511-516
• /
• 2002

Pitch is a perception related to the subjective frequency that is one of the psychological aspects or attributes of tones. It is also an important factor to determine the sound quality together with loudness and timber. Although the study on pitch has been active in the field of speech communication, but its application to the product sound quality is not yet enough. In this study, the empirical data by Zwicker is made use in the modification of the currently available pitch extraction model based on the place theory. By applying this modified model to various sound samples composed of tonal or banded components, the applicability of the model is suggested. As a demonstration example, the algorithm is used for the sound quality analysis of a product noise having fundamental frequency and harmonics. The result shows that the pitch should be regarded as an important subjective cue in the sound quality analysis.

• Earthquakes and Structures
• /
• 제15권2호
• /
• pp.155-164
• /
• 2018

Design of structures subjected to blast loads are usually carried out through nonlinear inelastic dynamic analysis followed by imposing acceptance criteria specified in design codes. In addition to comprehensive aspects of inelastic dynamic analyses, particularly in analysis and design of structures subjected to transient loads, they inherently suffer from convergence and computational cost problems. In this research, a strategy is proposed for design of steel moment resisting frames under far range blast loads. This strategy is inspired from performance based seismic design concepts, which is here developed to blast design. For this purpose, an algorithm is presented to calculate the capacity modification factors of frame members in order to simplify design of these structures subjected to blast loading. The present method provides a simplified design procedure in which the linear dynamic analysis is preformed, instead of the time-consuming nonlinear dynamic analysis. Nonlinear and linear analyses are accomplished in order to establish this design procedure, and consequently the final design procedure is proposed as a strategy requiring only linear structural analysis, while acceptance criteria of nonlinear analysis is implicitly satisfied.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2008년도 추계학술대회A
• /
• pp.1309-1313
• /
• 2008

This paper suggests an example of modification of the durability test specifications of electronic control unit for an automotive system in phase of design validation. The basic concept to redefine the specifications of durability test is based on the Arrhenius relationship for accelerated temperature test and the modified Coffin-Manson model for temperature cycle test. The ambient temperature of the powered-event durability test is increased to reduce the required test time of the current specification. Furthermore, the holding time between the events to cool down the temperature of the components is shortened and the resultant temperature rise affects the durability of the components. Thus, the acceleration factor due to the increased temperature range of temperature cycle is also estimated by the modified Coffin-Manson model.