• Food Science and Biotechnology
• /
• 제17권4호
• /
• pp.805-808
• /
• 2008

Ginsenosides are responsible for the pharmacological and biological activities of ginseng. In this study, ginsenoside Rh1 and compound K were isolated and purified from fermented ginseng substrate and their anti-allergic effects were assessed in compound 48/80-induced anaphylactic shock model. The fermented ginseng substrate was extracted by methanol and ginsenoside Rh1 and compound K were efficiently purified by preparative high performance liquid chromatography (prep HPLC). Their quality and quantity were analyzed by liquid chromatography-mass spectrometer (LC-MS) and HPLC. Ginsenoside Rh1 showed better anti-allergic effects than compound K in compound 48/80-induced anaphylactic shock model. This study suggested that fermented ginseng extracts with enriched Rh1 may be utilized as a potential biomaterial of functional food for the alleviation of allergic symptoms.

• 대한화학회지
• /
• 제22권6호
• /
• pp.403-411
• /
• 1978

Collagen의 model compound인 poly(Gly-Pro-Pro)의 수화에 관해서 empirical ppotential energy 함수를 사용하여 이론적으로 연구하였다. 물 분자와 model compound 간의 상호작용 energy를 최소화시켜서 물 분자들의 위치와 결합 energies를 계산하였다. 다음에는 일차수화층에 물이 붙음으로써 생기는 안정화 energy를 계산하고, 전체 안정화에 기여하는 여러 energy components의 기여도에 대해 논의하였다.

• 한국경영과학회:학술대회논문집
• /
• 대한산업공학회/한국경영과학회 1996년도 춘계공동학술대회논문집; 공군사관학교, 청주; 26-27 Apr. 1996
• /
• pp.100-103
• /
• 1996

Presented in this study is an algorithmic procedure to obtain polyhedral model from a compound surface. The compound surface in this study denotes a collection of trimmed surfaces without topological relations. The procedure consists of two main modules: CAD data interface, and surface conversion to polyhedral model. The interface module gets geometric information from CAD databases, and makes topological information by scanning the geometric information. We are investigating CATIA system as a data source system. In the surface conversion module, a shell(compound surface with topological information) is approximated to a triangular-faceted polyhedral surface model through node sampling and triangulation steps. The obtained polyhedral model should obey the vertex-to-vertex rule and meet tolerance requirements. Since the polyhedral model has a simple data structure and geometry processing for it is very efficient and robust, the polyhedral model can be used in various applications, such as surface rendering in computer graphics, FEM model for engineering analysis, CAPP for surface machining, data generation for SLA, and NC tool path generation.

• Communications for Statistical Applications and Methods
• /
• 제20권5호
• /
• pp.377-385
• /
• 2013

We consider a compound Poisson risk model in which the premium rate changes when the surplus exceeds a threshold. The explicit form of the ruin probability for the risk model is obtained by deriving and using the overflow probability of the workload process in the corresponding M/G/1 queueing model.

• Journal of applied mathematics & informatics
• /
• 제26권1_2호
• /
• pp.191-201
• /
• 2008

In this paper, we consider an insurance risk model governed by a compound Binomial arrival claim process and by a compound Binomial arrival premium process. Some formulas for the probabilities of ruin and the distribution of ruin time are given, we also prove the integral equation of the ultimate ruin probability and obtain the Lundberg inequality by the discrete martingale approach.

• Journal of the Korean Data and Information Science Society
• /
• 제23권6호
• /
• pp.1289-1297
• /
• 2012

We consider a general compound Poisson risk model in which the premium rate is surplus dependent. We analyze the joint distribution of the surplus immediately before ruin, the deffcit at ruin and the time of ruin by solving the integro-differential equation for the Gerber-Shiu discounted penalty function.

• 산업공학
• /
• 제23권3호
• /
• pp.205-212
• /
• 2010

The learning curve model is a mathematical form which represents the relationship between the manufacturing experience and its effectiveness. The semiconductor manufacturing is widely known as an appropriate example for the learning effect due to its complicated manufacturing processes. In this paper, I propose a new compound learning curve model for semiconductor products in which the general learning curve model and the growth curve are composed. The dependent variable and the effective independent variables of the model were abstracted from the existing learning curve models and selected according to multiple regression processes. The simulation results using the historical DRAM data show that the proposed compound learning curve model is one of adequate models for describing learning effect of semiconductor products.

• 한국태양에너지학회 논문집
• /
• 제32권6호
• /
• pp.100-105
• /
• 2012

In previous study, to investigate the impression of the compound lighting based on the AC-Model at the full-size room, the impressions of various compound lighting were completed as compared with that of the uniform lightings through the comparison method (a paired comparison) by Semantic Differential scaling. Also, we examined the effect of the supplementary lighting type increasing the lights at the side of the window and the blind-control lighting type, and they were compared with the existing compound lighting type. In results, pared comparison of the compound lighting and the uniform lighting, indicates that the impression of the compound lighting is generally similar to that of the uniform lighting when there are same ratios of the light from the window. Based on these results, we suggest that the AC-Model might be applied to various conditions. And we also introduce the method for daylighting that it is possible to reduce discomfort glare and to improve visual impressions as the supplementary type and blind-control type on the compound lighting. And it was found that electric power consumption of the compound lighting room was lower than that of the uniform lighting room when as same lighting ratio of the compound lighting and the uniform lighting from the window was provided or there was the lighting distribution simulated to same light ratio from the window. Since the method of the ACModel was described in the experimental condition, additional studies should be performed to determine if this model could be applied to different window configurations, lighting layout and types of a room.

• 임산에너지
• /
• 제20권1호
• /
• pp.35-41
• /
• 2001

리그닌 모델화합물 Ⅰ-Ⅳ의 시료를 315℃에서 열분해 시킨 결과, 리그닌 모델호합물 Ⅰ, Ⅱ의 열분해에서는 guaiacol이 0.47mol, DMP가 0.57mol로, DMAP는 0.12와 0.23mol로 각각 생성되었으며, 리그닌 모델화합물 Ⅲ, Ⅳ의 열분해에서는 guaiacol의 생성이 0.26mol, DMP가 0.30mol로 TMAP는 0.09mol 과 0.15mol이 각각 생성되었다. 리그닌 모델화합물 열분해 메커니즘으로서는 우선 탈수되고, 이어서 β-O-4 결합이 개열되어 guaiacol, DMP, DMAP와 TMAP가 생성되는 것을 알 수 있었다.

• 통합자연과학논문집
• /
• 제11권2호
• /
• pp.107-112
• /
• 2018

p38 MAP kinase belongs to the Mitogen-activated protein (MAP) kinase family; a serine/threonine kinase. It plays an important role in intracellular signal transduction pathways. It is associated with the development and progression of various cancer types making it a crucial drug target. Present study involves the HQSAR analysis of recently reported imidazo[1,2-b]pyridazine derivatives as p38 MAP kinase antagonists. The model was generated with Atom (A), bond (B), chirality (Ch), and hydrogen (H) parameters and with different set of atom counts to improve the model. An acceptable HQSAR model ($q^2=0.522$, SDEP=0.479, NOC=5, $r^2=0.703$, SEE=0.378, BHL=97) was developed which exhibits good predictive ability. A contribution map for the most active compound (compound 17) illustrated that hydrogen and nitrogen atoms in the ring A and ring B, as well as nitrogen atom in ring C and the hydrogen atom in the ring D provided positive activity in inhibitory effect while, the least active compound (compound 05) possessed negative contribution to inhibitory effect. Hence, analysis of produced HQSAR model can provide insights in the designing potent and selective p38 MAP kinase antagonists.