• Title/Summary/Keyword: Model Course

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Comparison of virulence by Acanthamoeba strains in a murine model of acquired immunodeficiency syndrome (면역결핍 마우스를 이용한 Acnnthamoeba 분리주별 병원성 평가)

  • Gong, Hyeon-Hui;Lee, Seong-Tae;Jeong, Dong-Il
    • Parasites, Hosts and Diseases
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    • v.36 no.1
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    • pp.23-32
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    • 1998
  • The pathogenic potential of Acnnthamoebc strains was evaluated by experimental infection of murine AIDS (MAIDS) model. C57BL/6 mice were induced to immunocompromized state by intraperitoneal injection of LP-BM5 MuLV and revealed the typical splenomegalty and Iymphatic enlargement of axillar and inguinal regios on necropsy 4 weeks after viral infection. Although there was no significant difference in the mortality rate of MAIDS mouse according to the culture temperature, it was very different in the mortality rate from strain to strain of Accnthnmoebc. A. henIHi OC-3A strain isolated from the brain of a GAE patient showed !he highest mortality rate and A. culbertsoni A-1 strain from tissue culture was the second. KA/S3 and KA/S2 strains isolated from soil revealed very low virulence. The mice infected by intranasal inoculation of Acanthnmoebc showed relatively chronic course than intravenous inoculation. The gross findings of lungs and brains from infected mice were variable among mice. On the microscopic observations, the lungs showed much more severe inflammation and necrosis than the brains microscopically. This MAIDS model would be useful to study the opportunistic protozoan infections of AIDS patients. In the light of these results. the pathogenic potential and the virulence of Acnnthamoebo may be determined genetically.

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Development Teaching-Learning Plan for 'Food and Nutrition unit' of Home Economics Based on Backward Design Model (백워드 설계 모형을 적용한 가정교과 식생활 단원의 교수·학습 과정안 개발)

  • Choi, SeoA;Ju, Sueun
    • Journal of Korean Home Economics Education Association
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    • v.30 no.3
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    • pp.175-193
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    • 2018
  • The course of home economics education is the one that fosters the ability to solve life problems. The life problem is permanent involving the individual, family, and society in overall. Thus, this study was to compose a class which applied the backward design model suggested by Wiggins and McTighe focusing on the usability of it in the educational filed of the home science to overcome the limitation of the education in the filed based on that critical mind. Therefore, this study developed the teaching·learning plan applying the backward design model to the 'Food and Nutrition' unit of the home economics education. It is expected that the unit and the teaching plan are used as materials for the class on the dietary life unit which is meaningful for learners in the educational field of the home economics education.

Exploring the Design of Artificial Intelligence Convergence Liberal Arts Curriculum Based on Flipped Learning and Maker Education: Focusing on Learner Needs Assessment (플립 러닝과 메이커 교육 기반 인공지능 융합교양교과목 설계 방향 탐색 : 학습자 요구 분석을 중심으로)

  • Kim, Sung-ae
    • Journal of Practical Engineering Education
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    • v.13 no.2
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    • pp.221-232
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    • 2021
  • The purpose of this study is to explore the design direction of artificial intelligence convergence liberal arts subjects based on flip learning and maker education through analysis of learner needs in a non-face-to-face classroom environment caused by COVID-19. To this end, we analyzed the priorities of subject content elements by using the Borich needs assessment and The Locus for Focus model along with students' perceptions of flip learning for students who took and did not take maker education-based liberal arts courses. Based on this, it was used as basic data for designing the curriculum. The study results are as follows. First, the content elements of the artificial intelligence liberal arts curriculum based on maker education consisted of a total of 9 areas and were designed as a class using flip learning. Second, the areas with the highest demand for education are 'Artificial Intelligence Theory', 'Artificial Intelligence Programming Practice', 'Physical Computing Theory', 'Physical Computing Practice', followed by 'Convergence Project', '3D Printing Theory', '3D Printing practice' was decided. Third, most of the questionnaires regarding the application of flip learning in maker education-based artificial intelligence liberal arts subjects showed positive responses regardless of whether they took the course, and the satisfaction of the students was very high. Based on this, an artificial intelligence-based convergence liberal arts curriculum using flip learning and maker education was designed. This is meaningful in that it provides an opportunity to cultivate artificial intelligence literacy for college students by preparing the foundation for artificial intelligence convergence education in liberal arts education by reflecting the needs of students.

GHG Mitigation Scenario Analysis in Building Sector using Energy System Model (에너지시스템 분석 모형을 통한 국내 건물부문 온실가스 감축시나리오 분석)

  • Yun, Seong Gwon;Jeong, Young Sun;Cho, Cheol Hung;Jeon, Eui Chan
    • Journal of Climate Change Research
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    • v.5 no.2
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    • pp.153-163
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    • 2014
  • This study analyzed directions of the energy product efficiency improvement and Carbon Tax for the domestic building sector. In order to analyze GHG reduction potential and total cost, the cost optimization model MESSAGE was used. In the case of the "efficiency improvement scenario," the cumulative potential GHG reduction amount - with respect to the "Reference scenario" - from 2010 to 2030 is forecast to be $104MtCO_2eq$, with a total projected cost of 2.706 trillion KRW. In the "carbon tax scenario," a reduction effect of $74MtCO_2eq$ in cumulative potential GHG reduction occurred, with a total projected cost of 2.776 trillion KRW. The range of per-ton GHG reduction cost for each scenario was seen to be approximately $-475{\sim}272won/tCO_2eq$, and the "efficiency improvement scenario" showed as the highest in the order of priority, in terms of the GHG reduction policy direction. Regarding policies to reduce GHG emissions in the building sector, the energy efficiency improvement is deemed to deployed first in the future.

Developing and Applying the Questionnaire to Measure High School Students' Unskeptical Attitude in Science Inquiry (과학탐구 상황에서 고등학생들의 반회의주의적 태도 측정도구 개발 및 적용)

  • Rachmatullah, Arif;Ha, Minsu
    • Journal of Science Education
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    • v.42 no.3
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    • pp.308-321
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    • 2018
  • The purpose of the study is to develop a questionnaire that examines unskeptical attitudes in scientific inquiry context. The questionnaire items were developed through literature research, expert review, and statistical analyses for validity and the differences in scores were identified by gender and tracks. A total of 363 high school students participated in the study. To explore the validity evidence of items, the Rasch analysis and the reliability of internal consistency were performed, and the two-way ANOVA was performed to compare the scores of the unskeptical attitudes between gender and academic track. Self-reporting and Likert-scaling 23 items were developed to measure unskeptical attitudes in scientific inquiry context. The items were developed in the sub-domain of scientific inquiry: 'questioning and hypothesis generating,' 'experiment designing,' and 'explaining and interpreting.' Second, the validity and reliability of the unskeptical were identified in a rigorous method. The validity of items were identified by multi-dimensional partial score model analysis through the Rasch model, and all 23 items were found to be fit to model. Various reliability evidences were also found to be appropriate. It was found that there were no significant differences of unskeptical attitude score between the gender and academic track except one comparison. The developed questionnaire could be used to check an unskeptical attitude in the course of scientific inquiry and to compare the effects of scientific inquiry classes.

Fandom-Persona Design based on Social Network Analysis (소셜 네트워크 분석을 이용한 팬덤 페르소나 디자인)

  • Sul, Sanghun;Seong, Kihun
    • Journal of Internet Computing and Services
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    • v.20 no.5
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    • pp.87-94
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    • 2019
  • In this paper, the method of analyzing the unformatted data of consumers accumulated on social networks in the era of the Fourth Industrial Revolution by utilizing data from the service design and social psychology aspects was proposed. First, the fandom phenomenon, which shows subjective and collective behavior in a space on a social network rather than physical space, was defined from a data service perspective. The fandom model has been transformed into a collective level of customer Persona that has been analyzed at a personal level in traditional service design, and social network analysis that analyzes consumers' big data has been presented as an efficient way to pattern and visually analyze it. Consumer data collected through social leasing were pre-processed by column based on correlation, stability, missing, and ID-ness. Based on the above data, the company's brand strategy was divided into active and passive interventions and the effect of this strategic attitude on the growth direction of the consumer's fandom community was analyzed. To this end, the fandom model of consumers was proposed by dividing it into four strategies that the brand strategy had: stand-alone, decentralized, integrated and centralized, and the fandom shape of consumers was proposed as a growth model analysis technique that analyzes changes over time.

A Study on Trainees' Awareness of Collision Risks (실습생의 충돌위험도 인식에 관한 조사 연구)

  • Kim, So-Ra;Park, Sang-Won;Sim, Hyo-Sang;Kim, Jong-Sung;Park, Young-Soo;Kim, Dae-Won
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.28 no.4
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    • pp.488-498
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    • 2022
  • Collision prevention education, which takes up the longest time among officer training courses, is one of the most important training and practice courses for trainees. The purpose of this study is to investigate the trainees' perception of collision risk in order to develop a systematic and quantified collision prevention training course. For this, factors for judging collision risk were derived from previous studies, and each trainee's perspective on collision risk was derived for each scenario through a questionnaire survey for trainees. Using the PARK Model, the same was compared with the collision risk perceived by the officer. Resultingly, it was found that trainees and of icers consider the distance to other ships the most important among collision risk factors. Additionally, although the risk trends of two groups for each scenario were similar, the average risk of trainees (5.39) was higher than that of officers (5.20). However, the trainees perceived a lower level of risk than the officers in certain scenarios, and this is judged to be the result of the trainees' lack of navigational experience. This study is expected to be used as basic data for the development of collision prevention practice education by quantitatively suggesting the difference between the collision risk of trainees and officers respectively.

Learning Ability Prediction System for Developing Competence Based Curriculum: Focusing on the Case of D-University (역량중심 교육과정 개발을 위한 학업성취도 예측 시스템: D대학 사례를 중심으로)

  • Kim, Sungkook;Oh, Chang-Heon
    • Journal of Practical Engineering Education
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    • v.14 no.2
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    • pp.267-277
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    • 2022
  • Achievement at university is recognized in a comprehensive sense as the level of qualitative change and development that students have embodied as a result of their experience in university education. Therefore, the academic achievement of university students will be given meaning in cooperation with the historical and social demands for diverse human resources such as creativity, leadership, and global ability, but it is practically an indicator of the outcome of university education. Measurement of academic achievement by such credits involves many problems, but in particular, standardization of academic achievement by credits based on evaluation methods, contents, and university rankings is a very difficult problem. In this study, we present a model that uses machine learning techniques to predict whether or not academic achievement is excellent for D-University graduates. The variables used were analyzed using up to 96 personal information and bachelor's information such as graduation year, department number, department name, etc., but when establishing a future education course, only the data after enrollment works effectively. Therefore, the items to be analyzed are limited to the recommended ability to improve the academic achievement of the department/student. In this research, we implemented an academic achievement prediction model through analysis of core abilities that reflect the philosophy, goals, human resources image, and utilized machine learning to affect the impact of the introduction of the prediction model on academic achievement. We plan to apply the results of future research to the establishment of curriculum and student guidance conducted in the department to establish a basis for improving academic achievement.

Corporate Default Prediction Model Using Deep Learning Time Series Algorithm, RNN and LSTM (딥러닝 시계열 알고리즘 적용한 기업부도예측모형 유용성 검증)

  • Cha, Sungjae;Kang, Jungseok
    • Journal of Intelligence and Information Systems
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    • v.24 no.4
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    • pp.1-32
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    • 2018
  • In addition to stakeholders including managers, employees, creditors, and investors of bankrupt companies, corporate defaults have a ripple effect on the local and national economy. Before the Asian financial crisis, the Korean government only analyzed SMEs and tried to improve the forecasting power of a default prediction model, rather than developing various corporate default models. As a result, even large corporations called 'chaebol enterprises' become bankrupt. Even after that, the analysis of past corporate defaults has been focused on specific variables, and when the government restructured immediately after the global financial crisis, they only focused on certain main variables such as 'debt ratio'. A multifaceted study of corporate default prediction models is essential to ensure diverse interests, to avoid situations like the 'Lehman Brothers Case' of the global financial crisis, to avoid total collapse in a single moment. The key variables used in corporate defaults vary over time. This is confirmed by Beaver (1967, 1968) and Altman's (1968) analysis that Deakins'(1972) study shows that the major factors affecting corporate failure have changed. In Grice's (2001) study, the importance of predictive variables was also found through Zmijewski's (1984) and Ohlson's (1980) models. However, the studies that have been carried out in the past use static models. Most of them do not consider the changes that occur in the course of time. Therefore, in order to construct consistent prediction models, it is necessary to compensate the time-dependent bias by means of a time series analysis algorithm reflecting dynamic change. Based on the global financial crisis, which has had a significant impact on Korea, this study is conducted using 10 years of annual corporate data from 2000 to 2009. Data are divided into training data, validation data, and test data respectively, and are divided into 7, 2, and 1 years respectively. In order to construct a consistent bankruptcy model in the flow of time change, we first train a time series deep learning algorithm model using the data before the financial crisis (2000~2006). The parameter tuning of the existing model and the deep learning time series algorithm is conducted with validation data including the financial crisis period (2007~2008). As a result, we construct a model that shows similar pattern to the results of the learning data and shows excellent prediction power. After that, each bankruptcy prediction model is restructured by integrating the learning data and validation data again (2000 ~ 2008), applying the optimal parameters as in the previous validation. Finally, each corporate default prediction model is evaluated and compared using test data (2009) based on the trained models over nine years. Then, the usefulness of the corporate default prediction model based on the deep learning time series algorithm is proved. In addition, by adding the Lasso regression analysis to the existing methods (multiple discriminant analysis, logit model) which select the variables, it is proved that the deep learning time series algorithm model based on the three bundles of variables is useful for robust corporate default prediction. The definition of bankruptcy used is the same as that of Lee (2015). Independent variables include financial information such as financial ratios used in previous studies. Multivariate discriminant analysis, logit model, and Lasso regression model are used to select the optimal variable group. The influence of the Multivariate discriminant analysis model proposed by Altman (1968), the Logit model proposed by Ohlson (1980), the non-time series machine learning algorithms, and the deep learning time series algorithms are compared. In the case of corporate data, there are limitations of 'nonlinear variables', 'multi-collinearity' of variables, and 'lack of data'. While the logit model is nonlinear, the Lasso regression model solves the multi-collinearity problem, and the deep learning time series algorithm using the variable data generation method complements the lack of data. Big Data Technology, a leading technology in the future, is moving from simple human analysis, to automated AI analysis, and finally towards future intertwined AI applications. Although the study of the corporate default prediction model using the time series algorithm is still in its early stages, deep learning algorithm is much faster than regression analysis at corporate default prediction modeling. Also, it is more effective on prediction power. Through the Fourth Industrial Revolution, the current government and other overseas governments are working hard to integrate the system in everyday life of their nation and society. Yet the field of deep learning time series research for the financial industry is still insufficient. This is an initial study on deep learning time series algorithm analysis of corporate defaults. Therefore it is hoped that it will be used as a comparative analysis data for non-specialists who start a study combining financial data and deep learning time series algorithm.

The role of antioxidant and DNA damage in the UVB-induced skin tumors of hairless mice

  • Bito, Toshinori;Budiyanto, Arief;Ueda, Masato;Ichihashi, Masamitsu
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.146-149
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    • 2002
  • Oxidative stress evoked hy Ultraviolet (UV) exposure has been suggested to be involved in UV-induced skin carcinogenesis. In this study, the role of oxidative stress in UV-carcinogenesis was evaluated by applying N-Acetylcysteine (NAC) in animal model of hairless-mouse. NAC is known to be a precursor of glutathione, which was converted to glutathione in cytoplasm, acting as an intracellular free radical scavenger. The glutathione levels in hairless mouse skin after one time application of NAC increased significantly. With and without the pre-treatment of NAC, hairless-mice were exposed to UVB three times a week, at total dose 274.4 kJ in 80 times, and the timing of tumor-development, incidence of skin tumor and the histopathology of tumors were observed. 8-hydroxy-2'-deoxyguanosine (8-0HdG), a typical form of oxidative damage in DNA has been also investigated in the course of experiment. The decrease of 8-0HdG formation of UVB- exposed skin compared to controls was observed in the early stage of experiment in the NAC-treated mice. In addition, initial tumor development delayed significantly in NAC-treated group. Finally the number of the tumor developed in the NAC-treated mice was fewer though not significant. These results suggest that antioxidants may have inhibitory effect in the initial step of UVB-induced carcinogenesis of hairless mice.

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