• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4061-4066
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• 2013

The extranodal natural killer/T-cell lymphoma (ENKTL) shows high local or systemic failure rates when radiotherapy (RT) is taken as the primary treatment, suggesting a role for chemotherapy (CT) added to RT for this disease. However, the appropriate mode of combined modality therapy (CMT) has not been fully defined. A total of one hundred and twenty-one patients with ENKTL receiving sandwich CT with RT were reviewed between January 2003 and August 2012. The primary endpoints were the response rate, progression-free survival (PFS), overall survival (OS), and the relapse rate. After the initial CT, there were 84 (69.4%) patients in CR, 22 (18.2%) patients in PR, 9 (7.4%) patients in SD, and 6 (5%) patients in PD, respectively. At the end of RT, the CR, PR, SD, and PD rates for all patients were 90.9% (n=110), 1.7% (n=2), 4.1% (n=5), and 3.3% (n=4), respectively. After a median follow-up of 42.3 months (3.5~112.3 months), the 5-year PFS was 74.7% (95% CI 70.4%~79.0%), and 5-year OS was 77.3% (95% CI 67.9%~86.7%). Disease progression was documented in 25 (20.7%) patients. The rates of systemic failure, local failure, and regional failure were 18.2%, 5.8%, 1.7%, respectively. Twenty death events (16.5%) were observed for the entire group of patients (18 deaths related to PD). Furthermore, CR to the initial CT and low Korean Prognostic Index (KPI) can independently predict long PFS and OS. The sandwich CMT achieved an excellent outcome for localized ENKTL with acceptable toxicity. We recommend it can be applied as the optimal choice for localized ENKTL.

• Analytical Science and Technology
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• v.30 no.1
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• pp.10-19
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• 2017

Anabolic steroids have similar structures to testosterone, both of which promote the growth of muscle mass and increase strength. However, the side effects of anabolic steroid use may lead to heart attacks or strokes. Additionally, the excessive use of steroids inhibits the production of the sex hormones in the body via a negative feedback loop, which results in testicular atrophy in males and amenorrhea in females. Currently, the method of choice used to test for the presence of anabolic steroids is GC-MS. However, GC-MS methods require chemical derivatization of the steroid sample to ensure compatibility with the analytical method; therefore, analysis of many different samples is difficult and time consuming. Unlike GC-MS, the liquid chromatography-quadrupole-time of flight mass spectrometry (LC-Q-TOF-MS) method is suitable for many samples. Twenty-two different anabolic steroids were analyzed by LC-Q-TOF-MS with various collision energies (CE). Accurate mass spectral data were obtained using a Q-TOF-MS equipped with an electro-spray ionization source and operated in the positive MS/MS mode for several classes of steroids that are often the targets of testing. Based on the collected data, fragmentation pathways were carefully elucidated. The high selectivity and sensitivity of the LC-Q-TOF-MS instrument combined with these fragmentation pathways offers a new approach for the rapid and accurate screening of anabolic steroids. The obtained data from the 22 different anabolic steroids will be shared with the scientific community in order to establish a library to aid in the screening of illegal anabolic steroids.

• Journal of the Economic Geographical Society of Korea
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• v.15 no.2
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• pp.332-342
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• 2012

The current research aims at classifying the bus stops as transfer center in order to establish the rational bus transfer systems. Existing research typically identifies characteristics of demands for bus stops and land use surrounding the bus stops and classifies and profiles the bus stops. A common problem with this type of research is that the results with cross-sectional characteristics of land use and bus stop usage do not capture the details of trip chain, the fundamental characteristics of the trips with transfer. This paper therefore examines bus stop classifications with such variables as transport mode chains, intermediate stop chains and timing chains. The analysis on the data collected on Monday 20 April 2009 for passengers of Gyeong-gi bus results in a clear classification among bus stops in terms of such trip chain variables. The research would provide useful information for the decision support of transfer stops location choice and infrastructure design.

• Journal of the Korean Society for Railway
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• v.12 no.5
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• pp.613-622
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• 2009

The modal spilt of highway has been increased and the one of railway has been decreased from 17.2%(1990) to 6.3%(2006). In this context, it is meaningful to examine the competitiveness of the railroad of Korea. The objective of this study is to analyze the competitiveness of railroad with the highway so that countermeasures improving the competitiveness of railroad could be suggested. For this, firs of all, indicators representing the competitiveness of the railroad transport are determined. The main influencing factors for mode choice include transport time, transport cost and level of service. Three types of commodity, container, cement and steel are the target for the analysis. It was found that the overall competitiveness of railroad transport is weaker compared with highway even for the main freight origin-destination pairs. It means that the freight transport system is focused on road rather than railroad. Therefore, we need to remeasure the competitiveness of railroad transport related to methods for freight railroad competitiveness improvement.

• Geophysics and Geophysical Exploration
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• v.12 no.1
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• pp.154-162
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• 2009

Sonic wave dispersion characteristics are one of the most important targets of study, particularly in estimating shear wave velocity from borehole sonic logging. We have tested dispersion characteristics using monopole and dipole sources. Theoretical dispersion curves were computed for tool-absent and tool-included models having the same physical properties but different diameters (including ${\Phi}520mm$, ${\Phi}150mm$, and ${\Phi}76mm$). Comparisons were made between boreholes of different sizes and between tool-absent and tool-included models. Between the tool-included and the tool-absent boreholes, a close similarity in dispersion curve shape was revealed for the monopole source, and a significant difference was shown for the dipole source. However, for the cut-off frequency, particularly in the engineering boreholes (${\Phi}76mm$ and ${\Phi}50mm$), a significant difference was observed for signals from the monopole source, but approximately the same cut-off frequencies were found with the dipole source. This indicates the need of careful choice of source frequency in monopole-source sonic logging, particularly in an engineering borehole. The results of numerical experiments show that cut-off frequency is exponentially proportional to the inverse of borehole radius, irrespective of the mode type and the presence of a tool, and that the cut-off frequencies for each borehole environment could be expressed as an exponential function, rather than the inversely proportional relationship between the cut-off frequency and the borehole radius that was previously generally recognised. From the direct comparison of dispersion curves, the effects on the dispersion characteristics of borehole size and the presence of the tool can be revealed more clearly than in previous studies, which presented the dispersion curve and/or characteristics for each borehole environment separately.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.6
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• pp.1170-1174
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• 2009

Two frequency-reconfigurable antennas have been designed and combined in a space with limited volume, i.e., 40mm ${\times}$ 20mm ${\times}$ 6mm. Each antenna can be reconfigured to operate at different frequency bands depending on the state of an embedded switch, which is implemented using a PIN diode. The first antenna can be switched between 0.82GHz ${\sim}$ 0.96GHz band (GSM/ CDMA) and 1.7GHz ${\sim}$ 2.17GHz band (DCS/ PCS/ WCDMA), which are cellular bands. The second antenna can be switched between 3.4GHz ${\sim}$ 3.6GHz band (mWiMax) and 2.3GHz ${\sim}$ 2.5GHz, 5.15GHz ${\sim}$ 5.35GHz bands (WiBro/ WLAN 11a/b/g/n), which are connectivity bands. The proposed combined antenna operates both over cellular bands and connectivity bands concurrently. The choice of the operation bands is made independently by the states of the two switches.

• Journal of Korean Society of Transportation
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• v.26 no.4
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• pp.51-61
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• 2008

Most of Korea's 15 local airports, with the exception Jeju, Gimpo and Gimhae airports, have been several billion Won in the red each year. It has been reported that one of the causes of the poor financial performance is inaccurate air traffic demand predictions. Under the situation, the entry of low-cost carrier air service using turbo-prop airplanes into the domestic airlines market gets a wide range of support, which is expected to promote the convenience of consumers and help to activate local airports. In this study, the authors (1) suggest a high-speed transport demand model among existing airlines, Korea Train Express (KTX) and low-cost carrier air service; (2) try to make low-cost air carrier demand predictions for a route between Seoul and Daegu through a stated-preference survey; and (3), examine possible effectiveness of selected policy measures by establishing an estimation model. First, fare has a strong influence for mode choice between high-speed transport modes when considering the entry of low-cost carrier air service between Seoul and Daegu. Even low-cost carrier air service fare is set at 38,000 won, which is considerably low compared with that of KTX, in the regions where the total travel time is the same for both low-cost carrier air service and KTX, the probability of selecting low-cost carrier air service is 0.1, which shows little possibility of modal change between high speed transportation means. It is suggested that the fare of low-cost air service between Seoul and Daegu should be within the range of from of 38,000 to 44,000 Won; if it is higher, the demand is likely to be lower than expected.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.18 no.5
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• pp.100-111
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• 2019

The existing selected station analysis (SSA) method analyzes the link transfer mode data between origin and destination of individuals passing through stations from a microscopic standpoint. As such, existing SSA is insufficient as it uses integrated analysis using macroscopic data such as subway lines. This research builds a line chain OD based on path search of individual passenger's movement through the subway, and explores means to utilize the findings. First, a method is proposed that searches the traversed subway path from the linked passage modes that the passenger uses and applies the results to SSA line analysis. Compared to the existing SSA, this method provides for analysis of commonly conflicting features such as the line on which the station is passed, and the stations included on the line thanks to the presence of complete information of the individual passenger's traversed path. It also allows for integrated observation of the line chain OD that approaches a certain station. For enhanced understanding, Seoul Metro Line 9 is used as a case study to demonstrate the integrated formulation concept of line chain OD centered around a certain station as well as the macroscopic features of the traversed path that approaches stations included on the line.

• Science of Emotion and Sensibility
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• v.26 no.2
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• pp.103-116
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• 2023

This study aims to investigate the interaction between inward bias and canonical viewpoint, which are factors known to affect preference for meaningful objects. It also considered the familiarity of each entity in terms of their influence on the existence of a canonical viewpoint and demonstrated whether the relative strength of two preferences varies depending on familiarity. To confirm this, we conducted a behavior experiment using a two-alternative forced-choice task. The experimental stimuli were eight single objects for familiarity level (high/low), whereas the entity's inward bias and canonical viewpoint were observed or violated. Results showed that when inward bias was obeyed, the frequency of being chosen as a preferred option was higher, and the reaction time for preference judgment was shorter. However, the observation of a canonical viewpoint did not affect frequency and reaction time. Moreover, familiarity played an interference role in aesthetic judgment. These results indicate that inward bias is stronger than canonical viewpoint, ultimately implying that a single object's interaction with the visual context is superior to the entity's attribute as regards to preference judgment.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.2
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• pp.209-217
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• 2022

Lane management with a central variable lane(s) (or reversible lane) where the traffic flow is temporarily reversed in one or more lanes during peak periods has been evaluated as an effective strategy to alleviate congestion caused by tidal traffic flows. However, due to traffic safety issues, such a movable barrier system can be considered as an alternative to supplement the existing its operation facilities such as static and/or dynamic signs and special pavement markings. In addition, when combined with a bus exclusive lane strategy, its effectiveness could be greatly increased. The objective of this study is to propose a feasibility analysis procedure for operational strategies of a bus-exclusive lanes using a barrier transfer system (BTS) for urban expressways. To this end, a case study was conducted on two urban expressways on the west side of the Han River in Seoul. As a result, temporary operation during rush hour in the morning was found to be most effective. The results presented in this study are expected to serve as a basis for establishing bus-exclusive lane operation strategies using similar systems in the future.