• 응용통계연구
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• 제23권3호
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• pp.511-520
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• 2010

약동학 모형은 약동학 모수들의 복잡한 비선형형태의 함수로 복잡한 미분방정식의 형태로 나타나기도 한다. 집단 약동학은 약동학 모형에서 약동학 모수들의 개인 간 차이를 나타내기 위해 이를 랜덤효과로 가정하므로 비선형 혼합 효과 모형이 된다. 본 논문에서는 임상약리학에서 약동학적 특징을 설명하기 위해 사용하는 집단 약동학 모형에 대한 통계학적 고찰을 해 본다. 또한 실제 임상자료를 이용하여 집단 약동학 모형을 적용하여 분석해 봄으로써 통계적 의미를 살펴본다.

• 한국염색가공학회지
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• 제18권5호
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• pp.48-52
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• 2006

A mixed adsorbent prepared by pyrolysing a mixture of carbon and flyash in 1:1 ratio was tested for its deceleration ability for three different classes of dyes, namely Astrazone Blue FRR(C.I. Basic Blue 69), Teflon Blue ANL(C.I. Acid Slue 125) and Verofix Red(Reactive Red 3GL). Equilibrium investigations were carried out at the optimum conditions obtained in the previous studies. The equilibrium data fitted reasonably well to both the Freundlich and Langmuir adsorption models. However the Langmuir model was more appropriate to describe the adsorption behavior of the dyes to the hybrid absorbent system compared with the Freundlich model. The mixed adsorbent cm be an low-cost alternative to activated carbons.

• Journal of Information Processing Systems
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• 제14권2호
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• pp.539-551
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• 2018

Images are unavoidably contaminated with different types of noise during the processes of image acquisition and transmission. The main forms of noise are impulse noise (is also called salt and pepper noise) and Gaussian noise. In this paper, an effective method of removing mixed noise from images is proposed. In general, different types of denoising methods are designed for different types of noise; for example, the median filter displays good performance in removing impulse noise, and the wavelet denoising algorithm displays good performance in removing Gaussian noise. However, images are affected by more than one type of noise in many cases. To reduce both impulse noise and Gaussian noise, this paper proposes a denoising method that combines adaptive median filtering (AMF) based on impulse noise detection with the wavelet threshold denoising method based on a Gaussian mixture model (GMM). The simulation results show that the proposed method achieves much better denoising performance than the median filter or the wavelet denoising method for images contaminated with mixed noise.

• Communications for Statistical Applications and Methods
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• 제27권3호
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• pp.377-383
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• 2020

The likelihood-based inference in a nonlinear generalized mixed model often requires computing moments of truncated multivariate normal random variables. Many methods have been proposed for the computation using a recurrence relation or the moment generating function; however, these methods rely on high dimensional numerical integrations. The numerical method is known to be inefficient for high dimensional integral in accuracy. Besides the accuracy, the methods demand too much computing time to use them in practical analyses. In this note, a moment calculation method is proposed under an assumption of a certain covariance structure that occurred mostly in generalized mixed models. The method needs only low dimensional numerical integrations.

• Structural Engineering and Mechanics
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• 제63권2호
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• pp.137-146
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• 2017

The size-dependent behavior of single walled carbon nanotubes (SWCNT) embedded in the elastic medium and subjected to the initial axial force is investigated using the mixed finite element method. The SWCNT is assumed to be Euler-Bernoulli beam incorporating nonlocal theory developed by Eringen. The mixed finite element model shows its great advantage of dealing with nonlocal behavior of SWCNT subjected to a concentrated load owing to the existence of two coefficients ${\alpha}_1$ and ${\alpha}_2$. This is the first numerical approach to deal with a puzzling fact of nonlocal theory with concentrated load. Numerical examples are performed to show the accuracy and efficiency of the present method. In addition, parametric study is carefully carried out to point out the influences of nonlocal effect, the elastic medium, and the initial axial force on the behavior of the carbon nanotubes.

• Journal of Mechanical Science and Technology
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• 제16권4호
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• pp.468-475
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• 2002

This paper reports on the friction characteristics of a piston ring pack with consideration of mixed lubrication. The analytical model is presented by using the average flow antral asperity contact model. The effect of operating condition, and design parameters on the MOFT, maximum friction force, and mean frictional power loss are investigated. Piston ring prick shows mixed and hydrodynamic lubrication characteristics. From the predicted results, it was fand that the ring tension and height of surface roughness have great influence on the frictional power losses in a ring pack. Especially, ring tension is a dominant factor for the reduction of friction loss and maintenance of oil film thickness.

• Water Engineering Research
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• 제3권3호
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• pp.155-162
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• 2002

This study presents the theoretical approach for volume concentration, velocity profile, and granular discharge on the fluid-granule mixed flow downstream of the scour hole at the outlet of the hydraulic structure. Concept of dilatant model was applied for the stress-strain relationships of fluid-granule mixed flow since the flow downstream of the scour hole corresponds to debris flow, where momentum transfers through particle collisions. Mathematical formulations were derived using momentum equation and stress-strain relation of the fluid-granule mixture. Velocity profile under the assumption of uniform concentration over flowing layer showed the downward convex type. Deposition angle of downstream hump was found to be a function of an upstream slope angle, a dynamic friction angle and a volume concentration irrespective of flow itself, Granular discharge and the overflow depth were obtained with given values of inflow rates. Experimental results showed relatively good agreements with theoretical ones.

• Journal of Electrical Engineering and Technology
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• 제8권4호
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• pp.675-685
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• 2013

Generation capacities and transmission line constraints in a competitive electricity market make it troublesome to compute Nash Equilibrium (NE) for analyzing participants' strategic generation quantities. The NE can cause a mixed strategy NE rather than a pure strategy NE resulting in a more complicated computation of NE, especially in a multiplayer game. A two-level hierarchical optimization problem is used to model competition among multiple participants. There are difficulties in using a mathematical programming approach to solve a mixed strategy NE. This paper presents heuristics applied to the mathematical programming method for dealing with the constraints on generation capacities and transmission line flows. A new formulation based on the heuristics is provided with a set of linear and nonlinear equations, and an algorithm is suggested for using the heuristics and the newly-formulated equations.

• 상하수도학회지
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• 제22권2호
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• pp.251-257
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• 2008

Food compost, having a higher organic contents than soil, could be an alternative material to prevent the proliferation of heavy metals contamination in soil. In this study we used a convection-dispersion local equilibrium sorption model(CDE) and a two-site non-equilibrium sorption model to find the effects on the adsorption and transportation of Pb by mixing food compost with soil and we also tried to find the effect of velocity and concentration of the injected solution on the characteristics of Pb. We measured Pb concentrations in injection-liquid and in effluent, and then applied them to CXTFIT program. As a result of column experiments, some parameters(D, R, ${\beta}$, ${\omega}$) used in two-site non-equilibrium adsorption model were obtained. Characteristics of Pb adsorption and transport were analyzed using the parameters(D, R, ${\beta}$, ${\omega}$) obtained from the CXTFIT program, We could know that mixed soil with food compost showed a higher adsorption capacity from the retardation factor(R) calculated from the breakthrough curve(BTCs) of Pb. Rs of soil and mixed soil are 20.45, 37.45 respectively, indicating that the adsorption and the transportation characteristics could be accessed quantitatively by using of two-site non-equilibrium adsorption model.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2007년도 공동학술대회 논문집
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• pp.317-322
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• 2007

Seismic exploration is divided by reflection and refraction method greatly, and reflection method can analyze complicated underground structure in the basis high resolution image, and refraction method can grasp the velocity structure of underground accurately. This thesis confirmed application of mixed exploration techniques using advantages of reflection and refraction. Reflection data processing applied conventional technique, and inversion of refraction data applied travel time tomographic technique that using SIRT method. Also, could establish initial information in model variable and improved the result of inversion by restricting model parameter value and dimension of area. Confirmed efficient fact in sequence and velocity structure grasping by utilizing accurate initial velocity model made out on the basis of marine reflection data, and mixed exploration technique using reflection and refraction have propriety that can trust in field application.