• Title/Summary/Keyword: Mist

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Comparison of minimally invasive surfactant therapy with intubation surfactant administration and extubation for treating preterm infants with respiratory distress syndrome: a randomized clinical trial

  • Sabzehei, Mohammad Kazem;Basiri, Behnaz;Shokouhi, Maryam;Ghahremani, Sajad;Moradi, Ali
    • Clinical and Experimental Pediatrics
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    • v.65 no.4
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    • pp.188-193
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    • 2022
  • Background: Respiratory distress syndrome (RDS) is a common cause of hospitalization and death in preterm infants who require surfactant treatment and respiratory support. Purpose: This study aimed to compare the clinical outcomes of minimally invasive surfactant therapy (MIST) and the INtubation, SURfactant administration, and Extubation (INSURE) technique in preterm infants with RDS. Methods: In this clinical trial, 112 preterm infants born at 28-36 weeks of gestation and diagnosed with RDS randomly received 200-mg/kg surfactant by MIST or the INSURE method. In the MIST group, surfactant was administered using a thin catheter (5F feeding tube); in the INSURE group, surfactant was administered after intubation using a feeding tube and the tracheal tube was removed after positive pressure ventilation was started. Nasal continuous positive airway pressure was applied in both groups for respiratory support and the postprocedure clinical outcomes were compared. Results: The mean hospitalization time was shorter for infants in the MIST group than for those in the INSURE group (9.19±1.72 days vs. 10.21±2.15 days, P=0.006). Patent ductus arteriosus was less frequent in the MIST group (14.3% vs. 30.4%, P=0.041). Desaturation during surfactant administration occurred less commonly in the MIST group (19.6% vs. 39.3%, P=0.023). There were no significant intergroup differences in other early or late complications. Conclusion: These results suggest that surfactant administration using MIST could be a good replacement for INSURE in preterm infants with RDS since its use reduced the hospitalization time and the number of side effects.

Chemistry of mist deposition of organic polymer PEDOT:PSS on crystalline Si

  • Shirai, Hajime;Ohki, Tatsuya;Liu, Qiming;Ichikawa, Koki
    • Proceedings of the Korean Vacuum Society Conference
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    • 2016.02a
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    • pp.388-388
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    • 2016
  • Chemical mist deposition (CMD) of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) was investigated with cavitation frequency f, solvent, flow rate of nitrogen, substrate temperature $T_s$, and substrate dc bias $V_s$ as variables for efficient PEDOT:PSS/crystalline (c-)Si heterojunction solar cells (Fig. 1). The high-speed camera and differential mobility analysis characterizations revealed that average size and flux of PEDOT:PSS mist depend on f, solvent, and $V_s$. The size distribution of mist particles including EG/DI water cosolvent is also shown at three different $V_s$ of 0, 1.5, and 5 kV for a f of 3 MHz (Fig. 2). The size distribution of EG/DI water mist without PEDOT:PSS is also shown at the bottom. A peak maximum shifted from 300-350 to 20-30 nm with a narrow band width of ~150 nm for PEDOT:PSS solution, whose maximum number density increased significantly up to 8000/cc with increasing $V_s$. On the other hand, for EG/water cosolvent mist alone, the peak maximum was observed at a 72.3 nm with a number density of ~700/cc and a band width of ~160 nm and it decreased markedly with increasing $V_s$. These findings were not observed for PEDOT:PSS/EG/DI water mist. In addition, the Mie scattering image of PEDOT:PSS mist under white bias light was not observed at $V_s$ above 5 kV, because the average size of mist became smaller. These results imply that most of solvent is solvated in PEDOT:PSS molecule and/or solvent is vaporized. Thus, higher f and $V_s$ generate preferentially fine mist particle with a narrower band width. Film deposition occurred when $V_s$ was impressed on positive to a c-Si substrate at a Ts of $30-40^{\circ}C$, whereas no deposition of films occurred on negative, implying that negatively charged mist mainly provide the film deposition. The uniform deposition of PEDOT:PSS films occurred on textured c-Si(100) substrate by adjusting $T_s$ and $V_s$. The adhesion of CMD PEDOT:PSS to c-Si enhanced by $V_s$ conspicuously compared to that of spin-coated film. The CMD PEDOT:PSS/c-Si solar cell devices on textured c-Si(100) exhibited a ${\eta}$ of 11.0% with the better uniformity of the solar cell parameters. Furthermore, ${\eta}$ increased to 12.5% with a $J_{sc}$ of $35.6mA/cm^2$, a $V_{oc}$ of 0.53 V, and a FF of 0.67 with an antireflection (AR) coating layer of 20-nm-thick CMD molybdenum oxide $MoO_x$ (n= 2.1) using negatively charged mist of 0.1 wt% 12 Molybdo (VI) phosphoric acid n-Hydrate) $H_3(PMo_{12}O_40){\cdot}nH_2O$ in methanol. CMD. These findings suggest that the CMD with negatively charged mist has a great potential for the uniform deposition of organic and inorganic on textured c-Si substrate by adjusting $T_s$ and $V_s$.

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A Study on the Extinguishing Performance of Water Mist with Additives (첨가제가 혼합된 미세물분무의 소화성능에 관한 연구)

  • 이경덕;신창섭
    • Fire Science and Engineering
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    • v.16 no.1
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    • pp.1-7
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    • 2002
  • Halogen-based fire suppressing agents have environmental problems because they cause the stratospheric ozone depletion and globe warming. Hence, fire suppression system using fine water mist became the center of interest as a substitution of halon. As a study about this, it is in progress to make the optimum droplet size by using water mist nozzles and to improve the extinguishing performance of water mist by using additives. Before this study, the extinguishing time of ethanol and n-heptane pool fire was measured with changing of water mist droplet size, flow density, discharge pressure, and fire size. In this study, on adding the additives to improve physical and chemical extinguishing performance of water mist, the extinguishing performance would evaluate and the optimum condition would find out. As a result, in case of ethanol pan 1 pool fire, the extinguishing time of the water mist by adding of 2.5 wt% NaCl and 0.3% AFFF got shorter 27% and 60% than the pure water mist. Adding of AFFF was to decrease the flame temperature by forming thin film on the fuel surface and to decrease the evaporation of n-heptane fuel. In case of NaCl, alkali salt crystals showed on the flame surface.

Examination on Fire Extinguishing Performance of Full Cone and Hollow Cone Twin-fluid Atomizers: Effects of Supply Gas and Water Mist (중실원추형 및 중공원추형 2유체 미립화기의 화재 소화 성능 검토: 공급 기체와 미분무 영향)

  • Kim, Dong Hwan;Lee, Chi Young
    • Fire Science and Engineering
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    • v.33 no.5
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    • pp.28-36
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    • 2019
  • In the present study, the effects of supply gas and water mist on the heptane pool fire extinguishing performance were investigated using the full cone and hollow cone twin-fluid atomizers. Air or nitrogen of 30 lpm (Liter per minute; L/min) was used as the supply gas, and the experiments were conducted under the water flow rate conditions of 0 lpm (i.e., discharge of air or nitrogen only) and 0.085 lpm (i.e., discharge of water mist with supply gas). Experimental results confirmed that the use of water mist discharge with the supply gas and full cone spray pattern reduced the fire extinguishing time as compared to that of only supply gas discharge and hollow cone spray pattern. In addition, for the discharge of water mist using the full cone twin-fluid atomizer, water mist significantly affected fire extinguishing performance, whereas the effect of the supply gas was less pronounced. On the other hand, for the discharge of water mist using the hollow cone twin-fluid atomizer, the fire extinguishing time was remarkably reduced by the supply of nitrogen, as compared with that of air, indicating that the supply gas as well as water mist can significantly affect fire extinguishing performance.

Growth Behavior of Heteroepitaxial β-Ga2O3 Thin Films According to the Sapphire Substrate Position in the Hot Zone of the Mist Chemical Vapor Deposition System (미스트화학기상증착 시스템의 Hot Zone 내 사파이어 기판 위치에 따른 β-Ga2O3 이종 박막 성장 거동 연구)

  • Kyoung-Ho Kim;Heesoo Lee;Yun-Ji Shin;Seong-Min Jeong;Si-Young Bae
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.36 no.5
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    • pp.500-504
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    • 2023
  • In this study, the heteroepitaxial thin film growth of β-Ga2O3 was studied according to the position of the susceptor in mist-CVD. The position of the susceptor and substrate was moved step by step from the center of the hot zone to the inlet of mist in the range of 0~50 mm. It was confirmed that the average thickness increased to 292 nm (D1), 521 nm (D2), and 580 nm (D3) as the position of the susceptor moved away from the center of the hot zone region. The thickness of the lower region of the substrate is increased compared to the upper region. The surface roughness of the lower region of the substrate also increased because the nucleation density increased due to the increase in the lifetime of the mist droplets and the increased mist density. Therefore, thin film growth of β-Ga2O3 in mist-CVD is performed by appropriately adjusting the position of the susceptor (or substrate) in consideration of the mist velocity, evaporation amount, and temperature difference with the substrate, thereby determining the crystallinity of the thin film, the thickness distribution, and the thickness of the thin film. Therefore, these results can provide insights for optimizing the mist-CVD process and producing high-quality β-Ga2O3 thin films for various optical and electronic applications.

Study on Pregnancy and Improvement of Fertilization rate by Micromanipulation (Partial Zona Dissection (PZD) and Micro-Insemination by Sperm Transfer(MIST) in human IVF-ET (체외수정시술시 미세조작술에 의한 수정률 향상과 임신에 관한 연구)

  • Lee, Ho-Joon;Choi, Kyoo-Wan;Jun, Jong-Yung;Park, Jong-Min;Kwon, Hyuck-Chan;Kim, Moon-Kyoo
    • Clinical and Experimental Reproductive Medicine
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    • v.17 no.1
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    • pp.57-63
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    • 1990
  • The purpose of this study is to improve fertilization rate in IVF-ET program of patients with male infertility used micromanipulation technique, partial zona dissection (PZD) or micro-insemination by sperm transfer (MIST). The results were as follows 1. The fertilization rate of non-micromanipulated oocytes and micromanipulated (PZD) oocytes were 12.5% (n=2) and 42.2% (n=19), respectively, and showed significant differences between two groups (p<0.05). 2. The fertilization rate of micromanipulated (MIST) oocytes was 30% (n=27). 3. The damage rate of Group 1 (PZD) and Group 2 (MIST) were 15.7% (3/19) and 29.6% (8/27), respectively. 4. One pregnancy resulted following replacement of micromanipulated (MIST) embryos in 4 patients.

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Update of minimally invasive surfactant therapy

  • Shim, Gyu-Hong
    • Clinical and Experimental Pediatrics
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    • v.60 no.9
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    • pp.273-281
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    • 2017
  • To date, preterm infants with respiratory distress syndrome (RDS) after birth have been managed with a combination of endotracheal intubation, surfactant instillation, and mechanical ventilation. It is now recognized that noninvasive ventilation (NIV) such as nasal continuous positive airway pressure (CPAP) in preterm infants is a reasonable alternative to elective intubation after birth. Recently, a meta-analysis of large controlled trials comparing conventional methods and nasal CPAP suggested that CPAP decreased the risk of the combined outcome of bronchopulmonary dysplasia or death. Since then, the use of NIV as primary therapy for preterm infants has increased, but when and how to give exogenous surfactant remains unclear. Overcoming this problem, minimally invasive surfactant therapy (MIST) allows spontaneously breathing neonates to remain on CPAP in the first week after birth. MIST has included administration of exogenous surfactant by intrapharyngeal instillation, nebulization, a laryngeal mask, and a thin catheter. In recent clinical trials, surfactant delivery via a thin catheter was found to reduce the need for subsequent endotracheal intubation and mechanical ventilation, and improves short-term respiratory outcomes. There is also growing evidence for MIST as an alternative to the INSURE (intubation-surfactant-extubation) procedure in spontaneously breathing preterm infants with RDS. In conclusion, MIST is gentle, safe, feasible, and effective in preterm infants, and is widely used for surfactant administration with noninvasive respiratory support by neonatologists. However, further studies are needed to resolve uncertainties in the MIST method, including infant selection, optimal surfactant dosage and administration method, and need for sedation.

Control and Investigation for Hazardous Characteristics of Metal Working Fluids Used in Korea - A Study on the Control and Sampling Method for Airborne MWF mist - (우리나라에서 사용하는 광물유의 유해특성과 관리대책에 관한 연구 - 공기중 MWF 미스트의 측정방법과 관리대책 -)

  • Paik, Nam-won;Park, Dong-wook;Yoon, Chung-sik;Cho, Sook-ja;Kim, Shin-bum;Lim, Ho-sub
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.7 no.2
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    • pp.171-180
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    • 1997
  • The objectives of this study were both 10 discuss the sampling method for airborne metalworking fluids(MWF)' mist and 10 suggest measures to minimize worker's exposure to carcinogen contained in metalworking fluids. In order to measure airborne MWF mist, it seems to be appropriate to use NIOSH Method #0500(filler weight) rather than NIOSH Method # 5026(analysis by FTIR). Because MWF mist on PVC filter evaporated and migrated during sampling, worker's exposure to MWF could be underestimated. So, when evaluating worker's exposure to MWF mist, other environmental conditions also must be considered. Enclosure and local exhaust ventilation system seems to he the most effective measure and must be constructed with process facility. In order to control worker exposure to carcinogens contained in MWF, distillation type and condition for crude oil, PAH concentration in MWF, and viscosity index of MWF must legally be described.

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A Study on the Irrigation System of Greenwell Using Ultrasonic Mist Fogger System (초음파안개분무시스템을 이용한 벽면녹화 관수시스템 개발 연구)

  • Kim, Kyung-Hoon;Kim, Yong;Sung, Hyun Chan
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.16 no.6
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    • pp.135-143
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    • 2013
  • Ultrasonic mist fogger and the fan were used for investigating the availability of fog circulation system in greenwall and the potential growing ability of the plant. The mist caused by ultrasonic mist fogger was circulated by the fan through the pipeline and supplied to the pots containing plants. Moisture content of the 3 different soils was measured at different irrigation time points. The moisture content of 15-26% in PP and Co soil was maintained at irrigation of 24H, 18H, 12H in a day. Proper growth condition was found in Ardisia pusilla and Hosta plantaginea at the height of L level after 1 month of growth when the plants were irrigated by the fog circulation system. The results suggest that the fog circulation, by ultrasonic mist fogger to the green walls is system of choice for suppling moisture to plants.

Optimum Fire Extinguishing Modeling using Impact Factor Analysis on Water Mist System of Pool Fire (영향인자 분석을 통한 고임화재의 미분무수 최적소화 모델링)

  • Hwang, Won-Jun;Kim, Hwang-Jin;Lee, Sung-Eun;Kim, Sung-Won;Oh, Kyu-Hyung
    • Fire Science and Engineering
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    • v.23 no.5
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    • pp.84-89
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    • 2009
  • In this study, the fire extinguishing experiment was performed using a water mist nozzle with variation of factors which affect on the extinguishing time. The variables were distance from nozzle center to fire location, droplet size, height of nozzle and opening or not. With the experimental data, interaction and sensitivity between factors were analysed with Mini tab and deduce a optimum model of fire extinguishing of water mist system. Based on the experiment and modeling of fire extinguishing with water mist system, the most important factor on extinguishing time is the distance from the center of nozzle to fire and the opening effect was small compare with other factors.