• The Journal of Korean Medicine
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• v.19 no.1
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• pp.127-144
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• 1998

According to the above, Myungsunrock(明善錄) written by 'Hansuckji(韓錫地);A.D.$1709{\sim}1803$' advocated his idea as well as criticized theory of 'Zhu Zi(朱子)' and influnced of the theory of 'SaSang Constitutional Medicine(四象醫學)' established by 'Lee Je-ma(李濟馬)' indirectly and directly inlater. Therefore it was as follows that the conclusion of the contents of Myungsunrock' and the philosophical basis of 'SaSang Constitutional Medicine(四象醫學)’. 1. Hansuckji was the 'Choungju Hanssi Rhevinyungongpa(淸州 韓氏) 禮'賓 尹a公n派)’ and descendanted with of the founder of his family and he was born in 1709, dead in 1803 at 95 age 2. Hansuckji was a scholar of a 'Yang Ming(陽明)’ that criticized study of 'Zhu Zi' and the group of 'Song(宋)' 3. Hansuckji defined that "Ge(格) is Zheng(正)". 4. Hansuckji advocated 'Zhi Xing He Yi Shuo(知行合一說)' 5. Hansuckji advocated that (we must) reach the 'Ming Shan(明善)' through the study and the means of 'Ming Shan' is as like as the means of 'Zhi Liang Zhi(致良知)' 6. Hansuckji explained of theory of 'Tiyong(體用)' instead of deviding into 'Tian Ren Xin Ming Li Qi(天 人 性 命 理 氣)' 7. The thought of Hansuckji delivered the theory of 'SaSang Constitutional Medicine(四象醫學:' established Lee Je-ma(李濟馬) directly and indirectly 8. Hansuckji is the first class of the scholars of 'Yang Ming' that included the contents of theory of 'Yang Ming' among the 'Yanlun(言論), directly 9. Lee Je-ma was obviously the third class of the scholars of 'Yang Ming' which advocating fundamental spirit of his whole life but he had no reference of the study of 'Yang Ming'.

• Parasites, Hosts and Diseases
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• v.51 no.2
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• pp.203-206
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• 2013

After bathing at a hot spring resort, a 75-year-old man presented to the emergency department because of seizure-like attack with loss of conscious. This is the first case of primary amebic meningoencephalitis (PAM) caused by Naegleria fowleri in Taiwan. PAM was diagnosed based on detection of actively motile trophozoites in cerebrospinal fluid using a wet-mount smear and the Liu's stain. The amoebae were further confirmed by PCR and gene sequencing. In spite of administering amphotericin B treatment, the patient died 25 days later.

• Advances in environmental research
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• v.1 no.3
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• pp.191-199
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• 2012

A kinetic study of the transesterification of soybean oil was conducted using microwaves under various temperatures, power densities, and reaction times. Results show that power density affects the kinetics and yield. The biodiesel yield increased with increasing microwave power density. The non-thermal effects of microwave irradiation on transesterification reactions were evaluated at a constant reaction temperature ($65^{\circ}C$) and power density (0.204 $Wg^{-1}$). Microwave irradiation was found to increase the reaction rates by 3.52-7.06 fold.

• Journal of Korean Medical classics
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• v.13 no.2 s.17
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• pp.85-85
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• 2000

Following is the result through translating. studying, and analyzing 『San Zhi Shan(三指禪)』, the book worked by Zhou Xue Ting(周學霆). 1. The chapter of 『Mai Xue Yuan Liu(脈學源流)』 explains thc Xiang Shu Xue(象數學) viewpoint, the part that pulse is based on Lu guan(律管). 2. The chapter of 『Liu Bu Mai Jie(六部脈解)』 explains that emphasizing Shen(神) through understanding the shape of pulse(脈象) is more important than the locating the area of thc shape of pulse(脈象). 3. The chapter of 『Zuo Xin Tan Zhong Can Dan Shen Xiao Chang You Fei Xiang Zhong Pi Wei Ming Da Chang Bian($좌심단중간담신소장{\cdot}우폐흉중비위명대장판$)』exhibits the different view about the position of pulse from Li Shi Zhen(李時珍)'s. the chapter in which Zhou(周) arranges Heart{\cdot}Small\;Intestine{\cdot}Liver{\cdot}Gall\;Bladder{\cdot}Kidneys{\cdot}and$ Bladcler($心{\cdot}小腸{\cdot}肝{\cdot}膽{\cdot}腎{\cdot}膀胱$) in left hand and $Lungs{\cdot}Large{\cdot}Intestine{\cdot}Spleen{\cdot}Stomach{\cdot}Kidney{\cdot}and$ The gate of Vitality($肺{\cdot}大腸{\cdot}脾{\cdot}胃{\cdot}腎{\cdot}命門$) in right hand. From the above results, I'm sure that 『San Zhi Shan(三指禪)』which has headed down to descendants as the special book about the study of pulse has developed the theory of pulse. Therefore I expect that the more profound study about this will be going on.

• Archives of Pharmacal Research
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• v.29 no.11
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• pp.946-951
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• 2006

One new stilbene glucoside (6), along with five known compounds (1-5), were isolated from the roots of Polygonum multiflorum Thumb., and their chemical structures established based on physicochemical and spectroscopic data. Of the compounds, compound 3 showed DNA topoisomerase I and II inhibitory activities.

• Bulletin of the Korean Chemical Society
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• v.30 no.3
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• pp.716-718
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• 2009

• Psychiatry investigation
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• v.15 no.11
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• pp.1064-1070
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• 2018

Objective Several cell line studies have demonstrated thioridazine's anticancer, multidrug resistance-reversing and apoptosis-inducing properties in various tumors. We conducted this nationwide population-based study to investigate the association between thioridazine use and cancer risk among adult patients with schizophrenia. Methods Based on the Psychiatric Inpatient Medical Claim of the National Health Insurance Research Database of Taiwan, a total of 185,689 insured psychiatric patients during 2000 to 2005 were identified. After excluding patients with prior history of schizophrenia, only 42,273 newly diagnosed patients were included. Among them, 1,631 patients ever receiving thioridazine for more than 30 days within 6 months were selected and paired with 6,256 randomly selected non-thioridazine controls. These patients were traced till 2012/12/31 to see if they have any malignancy. Results The incidence rates of hypertension and cerebrovascular disease were higher among cases than among matched controls. The incidence of hyperlipidemia, coronary artery disease and chronic pulmonary disease did not differ between the two groups. By using Cox proportional hazard model for cancer incidence, the crude hazard ratio was significantly higher in age, hypertension, hyperlipidemia, cerebrovascular disease, coronary artery disease and chronic pulmornary disease. However, after adjusting for other covariates, only age and hypertension remained significant. Thioridazine use in adult patients with schizophrenia had no significant association with cancer. Conclusion Despite our finding that thioridazine use had no prevention in cancer in adult patients with schizophrenia. Based on the biological activity, thioridazine is a potential anticancer drug and further investigation in human with cancer is warranted.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.9
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• pp.1215-1224
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• 2017

Objective: To assess the differences in ovarian transcriptomes in Shan Ma ducks between their peak and late stages of egg production, and to obtain new transcriptomic data of these egg-producing ducks. Methods: The Illumina HiSeq 2000 system was used for high throughput sequencing of ovarian transcriptomes from Shan Ma ducks at their peak or late stages of egg production. Results: Greater than 93% of the sequencing data had a base quality score (Q score) that was not less than 20 (Q20). From ducks at their peak stage of egg production, 42,782,676 reads were obtained, with 4,307,499,083 bp sequenced. From ducks at their late stage of egg production, 45,316,166 reads were obtained, with 4,562,063,363 bp sequenced. A comparison of the two datasets identified 2,002 differentially expressed genes, with 790 upregulated and 1,212 downregulated. Further analysis showed that 1,645 of the 2,002 differentially expressed genes were annotated in the non-redundant (NR) database, with 646 upregulated and 999 downregulated. Among the differentially expressed genes with annotations in the NR database, 696 genes were functionally annotated in the clusters of orthologous groups of proteins database, involving 25 functional categories. One thousand two hundred four of the differentially expressed genes with annotations in the NR database were functionally annotated in the gene ontology (GO) database, and could be divided into three domains and 56 categories. The three domains were cellular component, molecular function, and biological process. Among the genes identified in the GO database, 451 are involved in development and reproduction. Analysis of the differentially expressed genes with annotations in the NR database against the Kyoto encyclopedia of genes and genomes database revealed that 446 of the genes could be assigned to 175 metabolic pathways, of which the peroxisome proliferator-activated receptor signaling pathway, insulin signaling pathway, fructose and mannose metabolic pathways, gonadotropin releasing hormone signaling pathway and transforming growth factor beta signaling pathway were significantly enriched. Conclusion: The differences in ovarian transcriptomes in Shan Ma ducks between their peak and late stages of egg production were elucidated, which greatly enriched the ovarian transcriptomic information of egg-producing ducks.

• Asian-Australasian Journal of Animal Sciences
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• v.14 no.12
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• pp.1747-1751
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• 2001

An experiment was conducted to determine the effects of dietary oligosaccharides on performance and intestinal microbial populations of piglets. Ten litters of piglets were assigned to five groups randomly, with two litters per group. The control group was fed with corn-soybean basal diet. Oligosaccharides was added to the basal diet at the level of 0.05%, 0.1%, 0.2% and 0.35% respectively to form four experimental diets. The experiment was conducted with two periods. The first period (suckling period) was from 7 to 28 days of age and the second period (weanling period) was from 28 to 56 days of age. Fresh fecal samples were collected at 21 days of age and assayed for Escherichia coli concentration, pH and moisture content. Three pigs per group were slaughtered at 42 days of age and cecum, colon, and rectum content samples were collected and assayed immediately for Escherichia coli and Bifidobacterium concentration, pH and moisture content. The results showed that dietary oligosacchrides decreased fecal Escherichia coli population and pH significantly (p 0.05), but did not affect performance and fecal moisture content during suckling period. 0.1% oligosaccharides for weanling pigs increased growth and improved feed conversion ratio together with a reduction of diarrhea (p 0.05), but 0.35% oligosaccharides did not affect growth performance. 0.1% and 0.2% oligosaccharides for weanling pigs had a suppression to Escherichia coli colonization in rectum and an enrichment to Bifidobacterium in colon (p 0.05). Oligosaccharides decreased significantly (p<0.05) rectum moisture content, but did not affect cecum, colon and rectum pH.

• Geomechanics and Engineering
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• v.15 no.6
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• pp.1143-1151
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• 2018

Loess often causes problems when used as a filling material in the construction of foundations. Therefore, the compaction technique, shear behavior, and bearing capacity of a filled foundation should be carefully considered. A series of tests was performed in this study to obtain effective compaction techniques and construction parameters. The results indicated that loess is strongly sensitive to water. Thus, the soil moisture content should be kept within 12%-14% when it is used as a filling material. The vibrating-dynamic combination compaction technique is effective and has fewer limitations than other methods. In addition, the shear strength of the compacted loess was found to increase linearly with the degree of compaction, and the soil's compressibility decreased rapidly with an increase in the degree of compaction when the degree of compaction was less than 95%. Finally, the characteristic value of the bearing capacity increased with an increase in the degree of compaction in a ladder-type way when the degree of compaction was within 92%-95%. Based on the test data, this paper could be used as a reference in the selection of construction designs in similar engineering projects.