• Title/Summary/Keyword: Mineral mass

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Propranolol, a β-adrenergic antagonist, attenuates the decrease in trabecular bone mass in high calorie diet fed growing mice

  • Baek, Kyunghwa;Hwang, Hyo Rin;Park, Hyun-Jung;Kwon, Arang;Qadir, Abdul S.;Baek, Jeong-Hwa
    • BMB Reports
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    • v.47 no.9
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    • pp.506-511
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    • 2014
  • We investigated the effects of high calorie and low calorie diets on skeletal integrity, and whether ${\beta}$-adrenergic blockade (BB) attenuates bone loss induced by dietary calorie alteration. Male 6-week-old C57BL/6 mice were assigned to either an ad-lib fed control diet (CON), a high calorie diet (HIGH), or a low calorie diet (LOW) group. In each diet group, mice were treated with either vehicle (VEH) or propranolol, a ${\beta}$-adrenergic antagonist. Over 12-weeks, ${\beta}$-blockade mitigated body weight and fat mass increases induced by the high calorie diet. Femoral trabecular bone mineral density and the expression levels of osteogenic marker genes in bone marrow cells were reduced in HIGHVEH and LOWVEH mice, and BB significantly attenuated this decline only in HIGH mice. In summary, the magnitude of bone loss induced by low calorie diet was greater than that caused by high calorie diet in growing mice, and ${\beta}$-blockade mitigated high calorie diet-induced bone loss.

Internal Mixing of Pollutants for Submicron Particles Observed during Springtime in Japan

  • Matsumoto, Jun;Narukawa, Masahiro;Takahashi, Kenshi;Matsumi, Yutaka;Yabushita, Akihiro;Shimizu, Atsushi;Matsui, Ichiro;Sugimoto, Nobuo
    • Asian Journal of Atmospheric Environment
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    • v.3 no.1
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    • pp.27-41
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    • 2009
  • Internally mixed states of submicron particles during transport from the Asian continent to the Pacific Ocean were analyzed using a single-particle time-offlight mass spectrometer. The observation was conducted at Tsukuba in Japan in the spring of 2005 in order to investigate springtime transport of particles from the continent. The sum of ion intensities of sulfate (${HSO_4}^-$) detected in particles originating from the continental air masses counted for 75% of that in all particles during the observation. By analyzing correlations among compounds, origins and internally mixed states of compounds were estimated. It was found that nitrate was mixed with sulfate-rich particles as the air mass approached Japan. It was confirmed that Asian mineral dust particles played significant roles for transport of continental sulfate to Japan. As a result of analysis on internal mixing of chlorine and nitrate, it was implied that the chlorine loss in fine sea salt particles had already proceeded at Tsukuba. It was characteristic that fluoride ions were significantly detected, coal combustion in the Asian Continent can be an important source of fluorides detected in Japan through the westward transportation of fine particles including fluorides.

Bone Mineral Density, with Anthropometric Measurement, and Maternal Factors for Postmenopausal Women in Chungnam (폐경 후 여성들의 골밀도와 신체 측정치 및 모성 요인과의 관련성 연구 -충남 일부 지역을 중심으로-)

  • Park, Mie-Ja
    • The Korean Journal of Food And Nutrition
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    • v.20 no.4
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    • pp.450-459
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    • 2007
  • This study was performed to assess the relationships between bone mineral density(BMD), anthropometric measurements, and maternal factors in postmenopausal women. The anthropometric measurements were taken by a trained practitioner, and the maternal factors of the 85 subjects in Chungnam were acquired by an interview questionaire. The BMDs of the lumbar $spines(L_2-L_4)$, femoral necks(FN), ward's triangles(WT), and trochanters(TR) were measured by dual energy X-ray absorptiometry(DEXA). The BMDs(T-score) for $L_2-L_4$, FN, and WT were 0.996 $g/cm^2$(-1.601), 0.697 $g/cm^2(-1.657)$, and 0.793 $g/cm^2(-1.512)$ respectively, which were assessed as osteopenia by the T-score ; TR was noma1 at 0.718 $g/cm^2(-0.675)$. The 85 subjects in Chungnam were divided into three groups according to their BMD measurements for $L_2-L_4$ and FN, assessed by the T-score. The percentages in the osteoporosis, osteopenia, and normal groups were 32.9%, 42.4, and 24.7%, respectively. The average age was significantly the highest in the osteoporosis group than in the other two osteopenia and normal group(p<0.001). The subjects' BMDs were positively correlated with weight, height, BMI, waist, WHR, OBR and hip circumference, and negatively correlated with the age, duration time after menopause, lactation, the age of last delivery, menarche age, and number of children. The average age at menopause was 48.8. The osteoporosis group's average age at menopause was lower than those of the other groups. However, the BMD of the lumbar spine positively correlated with duration time after menopause and the BMD of the femoral neck with lactation, last delivery, menarch age, number of children. Therefore, researches are needed to find out the effective way to minimize the effect of age and other physiological conditions on the decrease of bone mass density.

Relation of Serum Calcium and Body Mass Index with Quantitative Ultrasound Attenuation of Adult Men and Women (성인남녀의 혈청칼슘 및 체질량지수와 골초음파상태와의 관계)

  • Kim, Min-Gyeong;Kim, Hui-Seon
    • Journal of the Korean Dietetic Association
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    • v.13 no.3
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    • pp.240-249
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    • 2007
  • The objective of this study was to investigate the relation of serum calcium level, body mass index(BMI) with bone status expressed as broadband ultrasound attenuation(BUA) measured by quantitative ultrasound (QUS) and the occurrence of osteopenia among adult men and women. Two hundred eleven(63 male and 148 female) workers who worked in 4 different battery factories were recruited from March 2005 to October 2005. BUA was used as a surrogate of bone mineral density and measured at left calcaneous bone area. The BUA value transformed into T-score by WHO standard conversion criteria to determine osteopenia (-2.5

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Long-lived cosmogenic nuclide, Beryllium-10 and its applications (장반감기 우주선유발 동위원소, $^{10}Be$과 그 응용)

  • Kim, K.J.;Jull, A.J.T;Woo, H.J.
    • The Korean Journal of Quaternary Research
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    • v.20 no.2
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    • pp.30-50
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    • 2006
  • The long-lived radionuclide, $^{10}Be$, is produced by cosmic-ray effects in the atmosphere of the earth as well as its surface and that of other planetary surfaces and atmospheres. Accelerator mass spectrometry (AMS) was developed in late 1970s, which made $^{10}Be$ terrestrial measurements more feasible. Since then, many research applications of $^{10}Be$ for both terrestrial and extraterrestrial applications have been developed, which parallel the wide range of radiocarbon ($^{14}C$) research applications. This paper summarizes production mechanisms of $^{10}Be$ both in the atmosphere and on the surface of terrestrial and extraterrestrial environments and also provides numerous $^{10}Be$ research applications in the fields of geomorphology, oceanography, archaeology, glaciology, cosmochemistry, climatology, and planetary science. We also review some $^{10}Be$ AMS research applications.

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A Study on Unburned Refractory for Ladle -Especially for Sling mass- (부소성 Ladle용 내화물에 관한 연구 -Sling mass의 특성을 중심으로-)

  • 박금철;한문희
    • Journal of the Korean Ceramic Society
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    • v.15 no.4
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    • pp.213-223
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    • 1978
  • The purpsoe of this study was to produce domestic stamping materials; sling mass which could be used as unburned refractory for iron melt'ladle. Batch compositions were based on Belgian Ladelite; mineral compositions were composed of 84 wt% of quartz and 16 wt% of clay, and particle sizes were divided into 12 wt% of 1410/297㎛, 18wt% 297/149㎛, 20wt% of 149/74㎛, 11wt% 74/44㎛ and 39wt% 44㎛ under. The effect of variable batch compositions were also investigated such as substitution of pyrophylite or industrial grade alumina for quartz and of zircon for portion of quartz and clay, increase of clay and addition on sericite. Samples were pressed at 100kg/㎠ with 7.4wt% of water or 7.4wt% of 4 wt% PVA solution. Dried and Fired properties of samples such as linear shrinkage, apparent porosity, modulus of rupture, refractoriness and corrosion resistance to blast furnace slag were investigated. The results are summarized as follows. 1. Dried samples are shrinked, but fired at 700-1400℃ expanded. Samples fired at 700-1000℃ and 1200-1400℃ tended to expand with incresing of firing temperature, but fired at 1000-1200℃ tended to shrink with increase of firing temperature. 2. Apparent porosity of samples fired at 700℃ is increased, but fired at 1200-1400℃ decreased with increasing of firing temperature. 3. Modulus of rupture of samples fired at 700℃ is decreased, but fired at above 700℃ increased with increasment of firing temperature. 4. Dried samples with 7.4 wt% of 4 wt% PVA solution better improve modulus of rupture than with 7.4 wt% of water, but the firing strength of the sampels fired at 700-1000℃ is showed reversely. 5. In quartz-clay system, mineral phases of samples fired at above 1200℃ are consisted of α-quartz, α-cristobalite and mullite. Respectively as firing temperature was rising up, intensity of α-cristobalite and mullite is in creased. 6. Quartz-Kibushi clay system, Kimcheun quartz(substitutuion of portion of industrial grade alumina for quartz) Hampyeung clay system and pyrophyllite-clay system are better in corrosion resistance to blast furnace slag than burned pyrophyllite brick. 7. 84 wt% of pyrophyllite-16wt% of clay system is superior in modulus of rupture and corrosion resistance to blast furnace slag to 84 wt% of quartz-16 wt% of clay system.

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Feature Extraction and Fusion for land-Cover Discrimination with Multi-Temporal SAR Data (다중 시기 SAR 자료를 이용한 토지 피복 구분을 위한 특징 추출과 융합)

  • Park No-Wook;Lee Hoonyol;Chi Kwang-Hoon
    • Korean Journal of Remote Sensing
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    • v.21 no.2
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    • pp.145-162
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    • 2005
  • To improve the accuracy of land-cover discrimination in SAB data classification, this paper presents a methodology that includes feature extraction and fusion steps with multi-temporal SAR data. Three features including average backscattering coefficient, temporal variability and coherence are extracted from multi-temporal SAR data by considering the temporal behaviors of backscattering characteristics of SAR sensors. Dempster-Shafer theory of evidence(D-S theory) and fuzzy logic are applied to effectively integrate those features. Especially, a feature-driven heuristic approach to mass function assignment in D-S theory is applied and various fuzzy combination operators are tested in fuzzy logic fusion. As experimental results on a multi-temporal Radarsat-1 data set, the features considered in this paper could provide complementary information and thus effectively discriminated water, paddy and urban areas. However, it was difficult to discriminate forest and dry fields. From an information fusion methodological point of view, the D-S theory and fuzzy combination operators except the fuzzy Max and Algebraic Sum operators showed similar land-cover accuracy statistics.

Effect of Modified Casein to Whey Protein Ratio on Dispersion Stability, Protein Quality and Body Composition in Rats

  • Jeong, Eun Woo;Park, Gyu Ri;Kim, Jiyun;Yun, So-Yul;Imm, Jee-Young;Lee, Hyeon Gyu
    • Food Science of Animal Resources
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    • v.41 no.5
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    • pp.855-868
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    • 2021
  • The present study was designed to investigate the effects of protein formula with different casein (C) to whey protein (W) ratios on dispersion stability, protein quality and body composition in rats. Modification of the casein to whey protein (CW) ratio affected the extent of protein aggregation, and heated CW-2:8 showed a significantly increased larger particle (>100 ㎛) size distribution. The largest protein aggregates were formed by whey protein self-aggregation. There were no significant differences in protein aggregation when the CW ratios changed from 10:0 to 5:5. Based on the protein quality assessment (CW-10:0, CW-8:2, CW-5:5, and CW-2:8) for four weeks, CW-10:0 showed a significantly higher feed intake (p<0.05), but the high proportion of whey protein in the diet (CW-5:5 and CW-2:8) increased the feed efficiency ratio, protein efficiency ratio, and net protein ratio compared to other groups. Similarly, CW-2:8 showed greater true digestibility compared to other groups. No significant differences in fat mass and lean mass analyzed by dual-energy x-ray absorptiometry were observed. A significant difference was found in the bone mineral density between the CW-10:0 and CW-2:8 groups (p<0.05), but no difference was observed among the other groups. Based on the results, CW-5:5 improved protein quality without causing protein instability problems in the dispersion.

Investigation of the Factors Affecting Bone Mineral Density in Children with Celiac Disease

  • Dehghani, Seyed Mohsen;Ilkhanipour, Homa;Samipour, Leila;Niknam, Ramin;Shahramian, Iraj;Parooie, Fateme;Salarzaei, Morteza;Tahani, Masoud
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.25 no.2
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    • pp.138-146
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    • 2022
  • Purpose: Children with celiac disease (CD) are at an increased risk of low bone mineral density (BMD) owing to malabsorption of fat-soluble vitamins, inflammation, and malnutrition. This study aimed to determine the prevalence and risk factors for low BMD in Iranian children with CD. Methods: This prospective cohort study examined 149 Iranian children with CD between 2011 and 2018 at Zabol University of Medical Sciences. BMD was measured using dual-energy X-ray absorptiometry. Demographic, clinical, and laboratory data were collected from patients' medical records. Logistic regression analysis was performed to identify the factors associated with low areal BMD (BMD-Z <-2) in the lumbar spine and femoral neck. Descriptive data were analyzed using the mean, standard deviation, and relative frequency. Data were analyzed using the chi-square test, t-test, and analysis of variance. Results: Of the 149 children with CD, 27.5% had osteoporosis. The mean body mass index (BMI) Z score was -1.28±1.2. Lower BMI was associated with a higher likelihood of BMD-Z (odds ratio 2.17; p≤0.05). Conclusion: Overall, the findings of this study showed that there was no correlation among Marsh classification, presence of specific human leukocyte antigens, and low BMD in Iranian children with CD. BMI can be a predictor of bone density in children with CD and may be applied clinically in early screenings to evaluate the bone health status in these children.

Mineralized Undifferentiated Duodenal Carcinoma in a Shih-Tzu Dog

  • Lee, Jiyeong;An, Soyon;Hwang, Gunha;Go, Woohyun;Lee, Jong-Bong;Noh, Seul Ah;Lee, Dongbin;Song, Joong-Hyun;Hwang, Tae Sung;Lee, Hee Chun
    • Journal of Veterinary Clinics
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    • v.39 no.5
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    • pp.258-263
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    • 2022
  • An eight-year-old, intact female, Shih-Tzu, weighing 4.5 kg presented with complaints of anorexia, pale mucous membrane, and vomiting for the past 5 days. On physical examination, nausea, abdominal pain, and melena were noted. On hematologic examination, severe anemia and thrombocytosis were identified. On radiographs examination, soft tissue opacity with small faint mineral opacity mass in the mid-abdomen and two mineral opacity regions in the cranial aspect of mass were identified. Ultrasonographic findings showed thickening of descending duodenal wall with loss of layering and mineralization within the duodenal wall and mesentery adjacent to the duodenal lesion. Computerized tomography showed circumferential wall thickening of descending duodenum with mineralization. Mineralization of the mesentery and mesenteric lymph nodes was identified. Based on the diagnostic imaging, the tentative diagnosis was descending duodenal tumor with dystrophic mineralization. Endoscopy revealed mucosal hemorrhage and erythema within the descending duodenum and stomach. Surgery was performed, and mineralization in the pancreatic tail to duodenum and mesentery was found. Resection of the duodenum, regional lymph node, and mineralized pancreatic region and the duodenal anastomosis were performed. The histologic examination revealed a high-grade undifferentiated duodenal carcinoma with metastases to the regional lymph node and mesentery. The patient was managed with supportive therapy for 8 days and discharged. The patient was followed up for 5 months and there were no complications.