• 한국심리학회지 : 문화 및 사회문제
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• 제16권4호
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• pp.469-485
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• 2010

본 연구는 현역 병사들의 입대 동기가 군 생활 전반에 미치는 영향을 알아보기 위해 육군 병사와 해병대원을 대상으로 수행되었다. 입대 동기란 군 복무를 하고자 하는 동기를 말하며, 본 연구에서는 외재적 입대 동기와 내재적 입대 동기로 나누어 측정하였다. 입대 동기에 따라 군 생활 만족도와 군 조직 이미지에 대한 평가, 그리고 군 복무 경험이 앞으로의 삶에 미칠 영향에 대한 평가가 어떻게 달라지는지 알아보았다. 그 결과 육군 병사들의 입대 동기는 외재적 동기가 더 높았으며, 해병대원들의 입대 동기는 내재적 동기가 더 높은 것으로 나타났다. 또한 내재적 입대 동기수준이 높을수록 군 생활 만족도가 높고, 군 조직에 대한 이미지도 긍정적으로 형성된 것으로 나타났으며, 미래의 삶에 군 생활 경험이 긍정적인 영향을 미칠 것으로 평가한 것으로 나타났다. 반대로 외재적 입대 동기수준이 높을수록 군 조직에 대해 부정적으로 평가하고, 병영생활 스트레스 수준이 높은 것으로 나타났으며, 앞으로의 삶에 군 생활 경험이 부정적인 영향을 미칠 것으로 평가하였다. 마지막으로, 징병제 여부에 관계없이 입대를 결정한 집단과 징병제가 아니면 군대를 오지 않을 집단을 비교한 결과 군 생활 영향 평가, 군 조직 이미지 평가, 병영 스트레스 수준에서 유의한 차이가 나타나는 것을 확인할 수 있었다. 이러한 결과를 통해 입대 전 입대 동기 유발의 중요성에 대해 논의하였다.

• 한국군사과학기술학회지
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• 제17권5호
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• pp.654-662
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• 2014

In the development of the weapon systems, utilization of Modeling & Simulation is growing in every aspect of development process. For the higher utilization of M&S, reuse of the M&S resources is needed to reduce the cost of M&S. I propose the M&S architecture framework that can enhance the reusability of the M&S resources in developing surface-to-air weapon systems. This M&S architecture design framework enables interoperability between the system and sub-systems. In this paper, the advantage and the necessity of the M&S architecture design framework will be described by introducing the cases that the M&S architecture framework reused in the combat experiments, the system development tests, the system operational tests and the concept developments in real projects. These cases will show the high reusability and efficiency of the M&S architecture design framework.

• 한국군사과학기술학회지
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• 제13권6호
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• pp.1080-1090
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• 2010

A study for improvement of credibility on test & evaluation result of interoperability in battle management information system which focused in C4I systems is very essential in rapid change of battle field environment. Realization of effective operation process with integration of developed IT also core factor for reducing of operational response time such as information gathering from sensor to shooter, time for commander's decision making. Therefore, by required to meet of high technical T&E, meet of complex software's user requirement, long-term system development period, system integration ability's request by various linkage of systems, it is high a M&S dependency to optimal performance, interpoerability's guarantee. Especially credibility on test & evaluation using M&S is very important. This paper will propse a VV&A applied methods using other VV&A case to improve credibility of M&S on test & evaluation.

• 한국국방경영분석학회:학술대회논문집
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• 한국국방경영분석학회 2008년도 국방경영분석 24권
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• pp.13-25
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• 2008

• 한국국방경영분석학회:학술대회논문집
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• 한국국방경영분석학회 2008년도 국방경영분석 24권
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• pp.79-89
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• 2008

• 한국군사과학기술학회지
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• 제7권1호
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• pp.24-33
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• 2004

Recently, ship acoustics takes more important role in acoustic stealth and classification of underwater targets. In this paper, a theoretical concept is proposed for M＆S-based test and evaluation of ship acoustics. The concept is based on two different approaches: on Top-Down method which emphasizes the survivability of the ship and on Bottom-Up method which considers acoustic characteristics of the ship-equipments. In order to improve the effectiveness of M＆S-based T＆E for ship acoustics, it is recommended in this paper to compromise the two approaches as adequate.

• 한국군사과학기술학회지
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• 제11권6호
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• pp.90-101
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• 2008

Korean defense specifications are the technical criteria of military products and major factor of acquisition system. Weapon systems and acquisition technique have been advanced dramatically after 1990's, but Korean defense specification practice standard has stayed after early 1980's except embedded software. The current status of current Korean defense specification practice standard and trend of related design and acquisition techniques like M&S, SBA, and digital manufacturing have been reviewed. This paper suggests that transfer to product, IT oriented specification structure, adaptation of digital product model and reinforcement of engineering management systems to establish a development initiative of Korean defense specification practice standard.

• BMB Reports
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• 제48권3호
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• pp.147-152
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• 2015

Small interfering RNA (siRNA) functions through pairing with specific mRNA sequences and results in the mRNA's degradation. It is a potential therapeutic approach for many diseases caused by altered gene expression. The delivery of siRNA is still a major problem due to its rapid degradation in the circulation. Various strategies have been proposed to help with the cellular uptake of siRNA and short or small hairpin RNA (shRNA). Here, we reviewed recently published data regarding local applications of siRNA. Compared with systemic delivery methods, local delivery of siRNA/shRNA has many advantages, such as targeting the specific tissues or organs, mimicking a gene knockout effect, or developing certain diseases models. The eye, brain, and tumor tissues are 'hot' target tissues/organs for local siRNA delivery. The siRNA can be delivered locally, in naked form, with chemical modifications, or in formulations with viral or non-viral vectors, such as liposomes and nanoparticles. This review provides a comprehensive overview of RNAi local administration and potential future applications in clinical treatment.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제25권1호
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• pp.1-12
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• 2023

Objective: Although chronic carotid artery occlusion seems to be associated with significant risk of ischemic stroke, revascularization techniques are neither well established nor widespread. In contrast, extracranial-intracranial bypass is common despite the lack of evidence regarding neurological improvement or prevention of ischemic events. The aim of current review is to evaluate the effectiveness of various methods of recanalization of chronic carotid artery occlusion. Methods: Comprehensive literature search through PubMed, Scopus, Cochrane and Web of Science databases performed. Various parameters were assessed among patients underwent surgical, endovascular and hybrid recanalization for chronic carotid artery occlusion. Results: 40 publications from 2005 to 2021 with total of more than 1300 cases of revascularization of chronic carotid artery occlusion have been reviewed. Further parameters were assessed among patients underwent surgical, endovascular and hybrid recanalization for chronic carotid artery occlusion: mean age, male to female ratio, mean duration of occlusion before treatment, rate of successful recanalization, frequency of restenosis and reocclusion, prevalence of ischemic stroke postoperatively, neurological or other symptoms improvement and complications. Based on proposed through reviewed literature indications for revascularization and predictive factors of various recanalizing procedures, an algorithm for clinical decision making have been formulated. Conclusions: Although treatment of chronic carotid artery occlusion remains challenging, current literature suggests revascularization as single option for verified neurological improvement and prevention of ischemic events. Surgical and endovascular procedures should be taken into account when treating patients with symptomatic chronic carotid artery occlusion.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3831-3836
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• 2013

Background: S100A14 has recently been implicated in the progress of several types of cancers. This study aimed to investigate the clinical significance and possible mechanisms of action of S100A14 in the invasion and metastasis of hepatocellular carcinoma (HCC). Methods: S100A14 expression in HCC was detected at mRNA and protein levels and its prognostic significance was assessed. Functional roles of S100A14 in HCC were investigated using MTT, BrdU, wound healing, transwell invasion assay and HCC metastatic mouse model. Results: S100A14 was significantly elevated in HCC tissues, correlated with multiple tumor nodes, high Edmondson-Steiner grade and vascular invasion. Multivariate Cox analysis showed that the S100A14 expression level was a significant and independent prognostic factor for overall survival (OS) of HCC patients (hazard ratio=1.98, 95% confidence interval=1.14-3.46, P=0.013). S100A14 promoted cell proliferation, invasion and metastasis of HCC in vitro and in vivo. Conclusion: These results suggest S100A14 is a novel prognostic marker and therapeutic target for HCC.