• Title/Summary/Keyword: Migration Strategy

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Pyloric Obstruction with Advanced Gastric Cancer: Stent vs. Bypass (악성 위출구 폐쇄 치료의 선택: 스텐트 삽입술 혹은 수술적 우회술?)

  • Lee, Beom-Jae;Park, Jong-Jae
    • Journal of Gastric Cancer
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    • v.9 no.1
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    • pp.1-5
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    • 2009
  • In the past, conservative bypass surgery was usually performed for palliation of malignant obstruction of the gastrointestinal tract. However, endoscopic stenting was developed recently, and technical advances and clinical experience have made it possible to establish stent implantation as one of the main treatment options. There are several advantages in stent implantation over bypass surgery, such as high feasibility and technical success rate, non-invasiveness, rapid symptomatic response, short hospitalization, and cost-effect benefits. Complications, such as stent ingrowth, stent injury by bile or acid, and migration, may occur and early re-insertion is frequently needed. Recently, diverse novel stents which are powered to predict stent migration or ingrowth have been developed and are being used in the clinical setting. In general, stent implantation is known to be beneficial in patients who are expected to survive <6 months, and surgical bypass may be more effective in patients who can survive >6 months. In this review, we have compared the technical feasibility, clinical outcomes, complications, and cost-benefit between stent implantation and bypass surgery, and determined the optimal treatment strategy in malignant upper gastrointestinal obstruction.

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A study of the methodology for the long-term preservation of electronic records : focus on the preservation concept (전자기록물의 장기보존을 위한 방안 연구 : 개념을 중심으로)

  • Nam, Sung-Un;Yoon, Dai-Hyun
    • Journal of Korean Society of Archives and Records Management
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    • v.1 no.2
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    • pp.101-119
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    • 2001
  • In this paper we explain the definition and component of electronic records, and reestablish the principle of the preservation. Also we discuss the conceptual approaches and requirements for long-term preservation in an electronic environment. The preservation in digital environment is to protect itself of record identity with the reliability and authenticity, and to ensure the accessibility of records. It needs to be periodical migration along with digital environment change for the long-term preservation of the electronic records. and to select software independent standard format. to ensure the integrity of electronic records along with this preservation strategy, process and relative information required for digital preservation are to record in the form of metadata. The preservation system is separated into four functional entities ; registration process, preservation process, access process, main record management system. Also, this article is conceptually to introduce the selection criteria of storage media, the security provision for the archive collections and the disaster recovery which apply to the digital archives.

Prognostic Value of Vascular Endothelial Growth Factor Expression in Patients with Prostate Cancer: a Systematic Review with Meta-analysis

  • Wang, Kai;Peng, Hong-Ling;Li, Long-Kun
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5665-5669
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    • 2012
  • Background: The vascular endothelial growth factor (VEGF) mediates vasculogenesis and angiogenesis through promoting endothelial cell growth, migration and mitosis, and has involvement in cancer pathogenesis, progression and metastasis. However, the prognostic value of VEGF in patients with prostate cancer remains controversial. Objectives: The aim of our study was to evaluate the prognostic value of VEGF in prostate cancer, and summarise the results of related research on VEGF. Methods: In accordance with an established search strategy, 11 studies with 1,529 patients were included in our meta-analysis. The correlation of VEGF-expression with overall survival and progression-free survival was evaluated by hazard ratio, either given or calculated. Results: The studies were categorized by introduction of the author, demographic data in each study, prostate cancer-relatived information, VEGF cut-off value, VEGF subtype, methods of hazard ratio (HR) estimation and its 95% confidence interval (CI). High VEGF-expression in prostate cancer is a poor prognostic factor with statistical significance for OS (HR=2.32, 95%CI: 1.40-3.24). However, high VEGF-expression showed no effect on poor PFS (HR=1.30, 95%CI: 0.88-1.72). Using Begg's, Egger's test and funnel plots, we confirmed lack of publication bias in our analysis. Conclusion: VEGF might be regarded as a prognostic maker for prostate cancer, as supported by our meta-analysis. To achieve a more definitive conclusion enabling the clinical use of VEGF in prostate cancer, we need more high-quality interventional original studies following agreed research approaches or standards.

Bis Is Involved in Glial Differentiation of PI9 Cells Induced by Retinoic Acid

  • Yoon, Jung-Sook;Lee, Mun-Yong;Lee, Jae-Seon;Park, Chan-Sun;Youn, Ho-Joong;Lee, Jeong-Hwa
    • The Korean Journal of Physiology and Pharmacology
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    • v.13 no.3
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    • pp.251-256
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    • 2009
  • Previous observations suggest that Bis, a Bcl-2-binding protein, may playa role the neuronal and glial differentiation in vivo. To examine this further, we investigated Bis expression during the in vitro differentiation of P19 embryonic carcinoma cells induced by retinoic acid (RA). Western blotting and RT-PCR assays showed that Bis expression was temporarily decreased during the free floating stage and then began to increase on day 6 after the induction of differentiation. Double immunostaining indicated that Bis-expressing cells do not express several markers of differentiation, including NeuN, MAP-2 and Tuj-1. However, some of the Bis-expressing cells also were stained with GFAP-antibodies, indicating that Bis is involved glial differentiation. Using an shRNA strategy, we developed bis-knock down P19 cells and compared them with control P19 cells for the expression of NeuroD, Mash-1 and GFAP during RA-induced differentiation. Among these, only GFAP induction was significantly attenuated in Pl9-dnbis cells and the population showing GFAP immunoreactivity was also decreased. It is noteworthy that distribution of mature neurons and migrating neurons was disorganized, and the close association of migrating neuroblasts with astrocytes was not observed in P19-dnbis cells. These results suggest that Bis is involved in the migration-inducing activity of glial cells.

Healthcare access challenges facing six African refugee mothers in South Korea: a qualitative multiple-case study

  • Kim, Min Sun;Song, In Gyu;An, Ah Reum;Kim, Kyae Hyung;Sohn, Ji Hoon;Yang, Sei Won
    • Clinical and Experimental Pediatrics
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    • v.60 no.5
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    • pp.138-144
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    • 2017
  • Purpose: Following legal reform in 2013, the annual number of asylum seekers entering South Korea has increased from 1,143 in 2012 to 5,711 in 2015. We interviewed six African refugee mothers of young children regarding their health needs and barriers to access maternal child health services. Methods: We recruited mothers who had visited a clinic for immigrants between July 2013 and August 2015. Participants were African refugee women, aged over 18 years, who had given birth in Korea within the previous 5 years and had come to Korea over a year before recruitment. Interview questions examined participants' experiences in pregnancy and childbirth and concerns regarding their child's health status. Initial data analysis involved all researchers' immersion in the entire collection of transcripts. We then noted recurrent topics and themes and identified similar issues. Results: At the time of giving birth, 5 participants were asylum seekers and one had undocumented status. The following barriers impeded their access to maternal child healthcare: socioeconomic factors (unstable social identity, low economic status, difficulty obtaining health insurance), language barriers (lack of linguistically appropriate health information, limited access to translation services), and cultural barriers (religious and cultural differences). Weak social support also hindered access to healthcare soon after migration; however, social links with the community emerged as a key coping strategy following settlement. Conclusion: We identified barriers to maternal and child healthcare and coping strategies among African refugee mothers in Korea. Future research should assess refugees' health status and improve health access and literacy among refugee mothers.

Silencing of Rac3 Inhibits Proliferation and Induces Apoptosis of Human Lung Cancer Cells

  • Liu, Tie-Qin;Wang, Ge-Bang;Li, Zheng-Jun;Tong, Xiang-Dong;Liu, Hong-Xu
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.3061-3065
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    • 2015
  • Background: Rac3, a member of the Rac family of small guanosine triphosphatases (GTPases), regulates a variety of cell functions, including the organization of the cytoskeleton, cell migration, and invasion. Overexpression of Rac3 has been reported in several human cancers. However, the role of Rac3 in lung cancer (LC) has not been determined in detail. The purpose of this study was to investigate the effect of silencing of Rac3 expression in human LC cells and the consequences for cell survival. Materials and Methods: Lentivirus small hairpin RNA (shRNA) interference techniques were utilized to knock down the Rac3 gene. Gene and protein expression was quantified by quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting. LC cell apoptosis was examined by annexin V-APC /propidium iodide staining. Results: Efficient silencing of Rac3 strongly inhibited A549 cell proliferation and colony formation ability, and significantly decreased tumor growth. Moreover, flow cytometry analysis showed that knockdown of Rac3 led to G2/M phase cell cycle arrest as well as an excess accumulation of cells in the G1 and S phase. Conclusions: Thus, functional analysis using shRNAs revealed a critical role for Rac3 in the tumor growth of LC cells. shRNA silencing of Rac3 could provide an effective strategy to treat LC.

The Effect of the Precedential Factors on the SNS User's Revisit and Switching Intention (SNS 이용자의 재방문의도와 전환의도에 영향을 미치는 선행요인에 관한 연구)

  • Yang, Chang-Gyu;Lee, Choong-Kwon;Huang, Yunchu
    • The Journal of Society for e-Business Studies
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    • v.19 no.2
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    • pp.125-142
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    • 2014
  • Previous research about SNS users' intention was mainly focused on revisit intention, while this study reaches a research conclusion by considering both revisit and switching intention. According to the research result, (1) social interaction and SNS addiction influence other precedential factors; (2) enjoyment and usefulness increase SNS users' revisit intention; (3) SNS users would not consider switching to another SNS even they have negative opinions about their current SNS. This research result implies that, for SNS enterprises to dominate market, it is required to provide services so that SNS users can actively participate on social interaction activities, and a strategy is necessary to attract and turn SNS users with negative opinions into active participants.

Reducing the frequency of processor thrashing using guarantee/reservation in process migration (작업 이주시 보장/예약 기법을 이용한 프로세서 쓰레싱 빈도 감소)

  • Lee, Jun-Yeon;Im, Jae-Hyeon
    • The KIPS Transactions:PartA
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    • v.8A no.2
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    • pp.133-146
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    • 2001
  • In a dynamic load distribution policies, each node gathers the current system sates information before making a decision on load balancing. Load balancing policies based on this strategy can suffer from processor thrashing. In this paper, we propose a new algorithm which attempts to decrease the frequency of the processor thrashing, the algorithm is based on the integration of three components. The first, the algorithm of which determine the size of jobs be transferred. The second, negotiation protocol with obtains a mutual agreement between a sender and a receiver on the transferring job size. And the third, a symmetrically-initiated location policy. The algorithm proposed in this paper used Siman IV as simulation tool to prove the improvement of performance. I analyzed the result of simulation, and compared with related works. The mean response time shows that there are no difference with existing policy, but appear a outstanding improvement in high load. The thrashing coefficient that shows the average response time, CPU overhead and the thrashing ratio at both the receiving and sending node has been used in the analysis. A significant improvement in the average response time and the CPU overhead ratio was detected using our algorithm when an overhead occurred in the system over other algorithm. The thrashing coefficient differed in the sending node and the receiving node of the system. Using our algorithm, the thrashing coefficient at the sending node showed more improvement when there was an overhead in the system, proving to be more useful. Therefore, it can be concluded that the thrashing ratio can be reduce by properly setting the maximum and minimum value of the system’s threshold queue.

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An open Scheduling Framework for QoS resource management in the Internet of Things

  • Jing, Weipeng;Miao, Qiucheng;Chen, Guangsheng
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.9
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    • pp.4103-4121
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    • 2018
  • Quality of Service (QoS) awareness is recognized as a key point for the success of Internet of Things (IOT).Realizing the full potential of the Internet of Things requires, a real-time task scheduling algorithm must be designed to meet the QoS need. In order to schedule tasks with diverse QoS requirements in cloud environment efficiently, we propose a task scheduling strategy based on dynamic priority and load balancing (DPLB) in this paper. The dynamic priority consisted of task value density and the urgency of the task execution, the priority is increased over time to insure that each task can be implemented in time. The scheduling decision variable is composed of time attractiveness considered earliest completion time (ECT) and load brightness considered load status information which by obtain from each virtual machine by topic-based publish/subscribe mechanism. Then sorting tasks by priority and first schedule the task with highest priority to the virtual machine in feasible VMs group which satisfy the QoS requirements of task with maximal. Finally, after this patch tasks are scheduled over, the task migration manager will start work to reduce the load balancing degree.The experimental results show that, compared with the Min-Min, Max-Min, WRR, GAs, and HBB-LB algorithm, the DPLB is more effective, it reduces the Makespan, balances the load of VMs, augments the success completed ratio of tasks before deadline and raises the profit of cloud service per second.

Clustering Strategy Based on Graph Method and Power Control for Frequency Resource Management in Femtocell and Macrocell Overlaid System

  • Li, Hongjia;Xu, Xiaodong;Hu, Dan;Tao, Xiaofeng;Zhang, Ping;Ci, Song;Tang, Hui
    • Journal of Communications and Networks
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    • v.13 no.6
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    • pp.664-677
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    • 2011
  • In order to control interference and improve spectrum efficiency in the femtocell and macrocell overlaid system (FMOS), we propose a joint frequency bandwidth dynamic division, clustering and power control algorithm (JFCPA) for orthogonal-frequency-division-multiple access-based downlink FMOS. The overall system bandwidth is divided into three bands, and the macro-cellular coverage is divided into two areas according to the intensity of the interference from the macro base station to the femtocells, which are dynamically determined by using the JFCPA. A cluster is taken as the unit for frequency reuse among femtocells. We map the problem of clustering to the MAX k-CUT problem with the aim of eliminating the inter-femtocell collision interference, which is solved by a graph-based heuristic algorithm. Frequency bandwidth sharing or splitting between the femtocell tier and the macrocell tier is determined by a step-migration-algorithm-based power control. Simulations conducted to demonstrate the effectiveness of our proposed algorithm showed the frequency-reuse probability of the FMOS reuse band above 97.6% and at least 70% of the frequency bandwidth available for the macrocell tier, which means that the co-tier and the cross-tier interference were effectively controlled. Thus, high spectrum efficiency was achieved. The simulation results also clarified that the planning of frequency resource allocation in FMOS should take into account both the spatial density of femtocells and the interference suffered by them. Statistical results from our simulations also provide guidelines for actual FMOS planning.