• Title/Summary/Keyword: Mig6

Search Result 45, Processing Time 0.023 seconds

Production of Plasma Leptin and Expression of Interferon-γ Inducible Protein-10 (IP-10), Monokine Induced by Interferon-γ (Mig) and Interleukin-8 (IL-8) mRNA in Kawasaki Disease

  • Lee, Young-Hwan;Kim, Won-Duk;Kim, Hee-Sun
    • IMMUNE NETWORK
    • /
    • v.2 no.4
    • /
    • pp.202-207
    • /
    • 2002
  • Background: Kawasaki disease is an acute febrile illness with systemic vasculitis which primarily affects children, We examined the production of leptin in plasma and gene expressions of CXC chemokines in peripheral blood mononuclear cells from patients with Kawasaki disease. Methods: Consecutive 39 samples from 13 patients according to the different clinical stages (acute, subacute, convalescent) of Kawasaki disease were collected. The plasma leptin levels according to clinical stages of Kawasaki disease were examined by ELISA and the expression of IP-10, Mig and IL-8 mRNAs in 39 samples (13 samples of each stage) from 13 cases were examined by RT-PCR. Results: There were not significant changes of plasma leptin levels according to the clinical stages of Kawasaki disease. The mean values of plasma leptin concentrations during each of the stages (n=13, p>0.05, pg/ml) were $335.8{\pm}549.0$ in acute, $358{\pm}347.6$ in subacute, and $443.6{\pm}645.9$ in convalescent stage. The mRNAs of IP-10, Mig, and IL-8 were expressed in 13/13 (100%), 2/13 (15%), 9/13 (69%) during acute stage, 13/13 (100%), 6/13 (46%), 13/13 (100%) during subacute stage, and 13/13 (100%), 4/13 (31%), 10/13 (77%) during the convalescent stage, respectively. In three patients, the production of leptin and expression of IP-10 mRNA were dramatically decreased according to the process of the clinical stages. In five patients with prominent cervical lymphadenopathy, the expression of IL-8 mRNA during the subacute stage was more elevated than the acute and convalescent stages. Conclusion: This data suggests that the production of leptin and the gene expressions of IP-10, Mig and IL-8 seem to have no significant correlation to the clinical stages of Kawasaki disease. However, expression patterns of IP-10, Mig and IL-8 mRNA may be related to the specific clinical manifestations, and the expression of IP-10 may also be correlated to leptin levels with pericardial involvement.

Prediction of Tensile Strength for Plasma-MIG Hybrid Welding Using Statistical Regression Model and Neural Network Algorithm (통계적 회귀 모형과 인공 신경망을 이용한 Plasma-MIG 하이브리드 용접의 인장강도 예측)

  • Jung, Jin Soo;Lee, Hee Keun;Park, Young Whan
    • Journal of Welding and Joining
    • /
    • v.34 no.2
    • /
    • pp.67-72
    • /
    • 2016
  • Aluminum alloy is one of light weight material and it is used to make LNG tank and ship. However, in order to weld aluminum alloy high density heat source is needed. In this paper, I-butt welding of Al 5083 with 6mm thickness using Plasma-MIG welding was carried out. The experiment was performed to investigate the influence of plasma-MIG welding parameters such as plasma current, wire feeding rate, MIG-welding voltage and welding speed on the tensile strength of weld. In addition we suggested 3 strength estimation models which are second order polynomial regression model, multiple nonlinear regression model and neural network model. The estimation performance of 3 models was evaluated in terms of average error rate (AER) and their values were 0.125, 0.238, and 0.021 respectively. Neural network model which has training concept and reflects non -linearity was best estimation performance.

The development of welding process to prevent porosity in high speed MIG Welding of Al 6082-T6 (Al 6082-T6 고속 MIG 용접에서 기공방지를 위한 용접공정 개발)

  • Jung, Yun-Ho;Park, Kyung-Do;Baek, Sang-Yeob;Oh, Dong-Soo;Sung, Young-Ki;Kim, Jeong-Pyo;Cho, Sang-Myung
    • Proceedings of the KWS Conference
    • /
    • 2009.11a
    • /
    • pp.8-8
    • /
    • 2009
  • 알루미늄 합금 Al 6082-T6는 최근에 개발되어 북유럽 등의 선진국에서는 그 뛰어난 해양 내식성과 우수한 강도로 인하여 해양구조물의 헬리데크(Helideck), 타워 갱웨이(Tower gangway), 알루미늄 피팅류(Aluminium fitting)등의 해양구조물과 플랫폼(Flatform), 알루미늄 래더(Aluminium ladder)등의 선박부품, 차량, 기계부품 분야에서 전 세계적으로 널리 사용되기 시작하였다. 그러나 전통적으로 용접금속의 기공은 결함으로 분류 되고, Rakesh Kumar 등의 논문에 따르면 용접 시 용접금속 내에 발생되어진 미세기공이 기계적 성질에 악영향을 미치는 것으로 보고되어졌다. 따라서 용접금속내의 발생하는 기공을 방지하는 용접공정의 개발이 반드시 필요하다. 본 연구의 목적은 Al 6082-T6 고속 MIG용접에서 기공방지를 위한 용접공정을 개발하는 것이다. Al 6082-T6의 7t 플레이트에 Al 5356의 와이어를 사용하여 아크길이 변경 및 용접속도를 60cpm과 120cpm으로 변경하여 실험하였고, 용접속도 120cpm의 고속 MIG용접에서 토치 진행각을 변경하여 실험을 진행하였다. 용접공정 파라메터 변경에 따른 기공율 측정은 이미지 분석 소프트웨어를 사용하여 정량적으로 분석하였다.

  • PDF

Mechanical and electrochemical characteristics with welding materials in robotic MIG welding of dissimilar Al alloys (이종 알루미늄 합금의 로봇 미그 용접 시 용접재료에 따른 기계적 및 전기화학적 특성 평가)

  • Kim, Seong Jong;Han, Min Su;Woo, Yong Bin
    • Corrosion Science and Technology
    • /
    • v.12 no.5
    • /
    • pp.245-252
    • /
    • 2013
  • In this study, mechanical and electrochemical characteristics with welding material in MIG welded with ROBOT for dissimilar Al alloys were investigated using various experiment methods. The MIG welding by ROBOT with ER5183 and ER5556 for the 5456-H116 and 6061-T6 Al alloy were carried out. The hardness of welding zone was lower than that of base metal. In electrochemical experiment, ER5183 welding material presented excellent characteristics. The yield strength and maximum tensile strength in welding with welding material of ER5183 presented lower value than those of ER5556. The elongation and time-to-fracture showed the opposite results.

EFFECTS OF AGING TREATMENT ON MICROSTRUCTURE AND STRENGTH OF WELD HEAT AFFECTED ZONE OF 6N01-T5 ALUMINUM ALLOY

  • Yoshida, Naoharu;Shibao, Masami;Ema, Mitsuhiro;Sasabe, Seiji;Hirose, Akio;Kobayashi, Kojiro F.
    • Proceedings of the KWS Conference
    • /
    • 2002.10a
    • /
    • pp.59-64
    • /
    • 2002
  • Effects of the aging treatments on the microstructure and strength of heat affected zone(HAZ) in the welds of a age-hardened Al-Mg-Si alloy, 5N01-T5, were investigated. The base metal aging treatments before MIG welding were conducted at 423K to 473K for 28.8ks Post weld heat treatment(PWHT) to recover the HAZ strength was performed at 448K for 28.8ks. Microstructure observations, hardness measurements and tensile tests were conducted to study properties of the MIG weld joints. The position of the softest region in HAZ where the hardness insufficiently recovered after natural aging and PWHT was at a distance of approximately 15mm from the center of the fusion zone. Hardness of the softest regions after natural aging and PWHT decreased with increase in the base metal aging temperature. TEM observation clarified that strengthening ${\beta}$"(Mg$_2$Si) precipitates and coarse ${\beta}$′ precipitates affected the hardnes of HAZ. Incomplete recover of hardness in HAZ after PWHT was caused by the precipitating of non-hardening ${\beta}$′ phase during the weld thermal cycle. In order to examine the effects of weldheat input and welding speed, the laser weld joints were also investigated and compared with the MIG weld ones. Laser welding had the narrower width of the softened regions in HAZ compared with MIG welding. The hardness of the softest regions of the laser welds after PWHT was higher than that of the MIG welds. Quantitative relations between hardness of the softest region and base metal aging temperature were obtained for both welding processes. Accordingly, the equations to estimate the strength of the weld joints after PWHT with varying base metal temperatures were proposed for MIG welding and laser welding.

  • PDF

Load Balancing in Seamless Game with MigAgent (MigAgent를 이용한 Seamless 게임에서의 부하 분산)

  • Kim, Beob-Kyun;Jang, Hang-Jin;You, Kang-Soo
    • Journal of Internet Computing and Services
    • /
    • v.7 no.6
    • /
    • pp.51-62
    • /
    • 2006
  • The load of this kind of gores, which is heavier than that of any other precedent, and on enormous seamless virtual world characterize the MMORPG(Massively Multiplayer Online Role-Playing Game) genres. In this seamless environment, gamers can usually accept a set of independent spaces, which is being held by independent game servers, os a single big virtual world. Despite the efforts of some developers, gamers are suffered from huge message traffic which comes from the interaction between client and server and the interaction between fold sowers. In this paper, new gore server architecture using MigAgent is proposed which tries to reduce message traffic. Usually, message traffic reaches the climax when a PC(Player Character) is moving to other field server. MigAgent, designed in this thesis, tries to manage this kind of PCs and to ploy o role of user's agent to prepare for the unexpected situation. Improvement of this system is shown by the analysis of the effect of the size ratio of AOI (Area of Interest) and AC (Adjacent Cell).

  • PDF

Evaluation of the Effect of Rotating Tool for Friction Stir Welding Al6005-T6 (회전공구 회전속도에 따른 알루미늄 합금 (Al6005-T6)의 마찰교반접합 특성 연구)

  • Choi, Dooho
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.18 no.11
    • /
    • pp.124-129
    • /
    • 2017
  • In this study, we report characteristics of friction stir welding (FSW) technique applied to Al-6005-T6 extruded sheets, which is a common material for railway car bodies. With the welding speed fixed at 300 mm/min, the revolution per minute (RPM) of the rotating tool was varied from 600 to 1800 RPM, with the aim at evaluating the resultant microstructure and mechanical behaviors. Comparison is also made with the conventional Metal Inert Gas (MIG) welding technique. Unlike MIG, no micro-voids were observed for FSW specimens. Hardness measurement revealed that the increased heat input by increasing RPM results in widened heat affected zone (HAZ) and decreased hardness for HAZ due to grain coarsening. Hardness results for the nugget do no show difference. During tensile tests, specimens fractured at HAZ, and increasing rpm led to decrease of the yield stress and tensile stress for the selected RPM range, which is considered to be due to the grain coarsening for HAZ.

Study on Weldability of A5052-H32 Sheet using Nd : YAG Laser-MIG Hybrid Welding (하이브리드(CW Nd : YAG Laser + MIG) 용접을 이용한 A5052-H32 맞대기 용접부의 역학적 특성에 관한 연구)

  • Kim, Jun-Hyung;Bang, Han-Sur;Bijoy, M.S.;Jeon, Geun-Hong;You, Jea-Sun;Bang, Hee-Seon
    • Journal of Ocean Engineering and Technology
    • /
    • v.24 no.6
    • /
    • pp.92-96
    • /
    • 2010
  • Recently, the application of aluminum alloys has been increasing for lightweight and high quality transport vehicles. Therefore, the proposal has been made to apply high speed hybrid welding methods to the marine grade aluminum alloy (A5052) used for shipbuilding by combining a 3-KW CW Nd : YAG laser and the MIG welding process. In this study, the characteristics of the welding parameters were investigated for a hybrid butt joint. This paper also describes the determination of the heat distribution in a weldment and the welding residual stress using a finite element method. Mechanical experimentation was also used to ascertain the reliability of the weldment.

Characteristics of the Hard-Overlayers by WC-12%Co Powder Addition in MIG Welding of Al Alloy (Al 합금의 MIG 용접에서 WC-12%Co 분말에 첨가에 의한 경화육성층의 특성)

  • 박정식;양병모;박경채
    • Journal of Welding and Joining
    • /
    • v.18 no.6
    • /
    • pp.102-107
    • /
    • 2000
  • It was attempted to improve the wear resistance of Al alloy under the load condition by making a formation of the thick surface hardening alloy layers. The thick surface hardening alloy layers were formed on 6061 Al alloys overlayed by MIG welding process with WC-12%Co powder addition. Effects of the dispersion of WE-12%Co powders on hardness and wear characteristics of alloys were investigated. The following results were obtained. Most of WE-12%Co powders are dispersed nearly uniform as unmelted particles in the matrix alloy. A part of WC-12%Co powders are melted in the molten pool, and during solidification {TEX}$Al_{9}Co_{2}${/TEX} appeared. With increasing addition of WC-12%Co powders, the hardness and specific wear resistance of the overlay weld alloys increased and reached Hv450 at WC-12%Co powder addition rate of 54g/min. It is considered that excellent wear resistance of the overlayed alloys was due to dispersed WC-12%Co powders and increased 10 times at WC-12%Co powder addition rate of 54 g/min than that of the WC-free overlaying layers.

  • PDF