• 대한지역사회영양학회지
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• 제25권4호
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• pp.329-339
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• 2020

Objectives: This study was undertaken to evaluate the intake of vitamins and minerals from dietary supplements (DSs) in Korean adults and elderly. Methods: Data for this study was generated from the 2017 Korea National Health and Nutrition Examination Survey (KNHANES). We analyzed 4,204 individuals aged 19 years and older (2,579 users and 1,625 non-users). The survey included 24-h recall questions on food and DS intakes, as well as questions on DS use over the past year. The nutrient DSs evaluated were calcium, phosphorus, iron, vitamin A, thiamin, riboflavin, niacin, and vitamin C. Total nutrient intakes were obtained by combining nutrient intakes of foods and DSs consumed by each subject. Results: Most micronutrient intakes from food (except for thiamin) in adult users, and the four micronutrient intakes (iron, vitamin A, vitamin B₂ and vitamin C) in elderly users, were significantly higher than values obtained in non-users. For total intake of nutrients and DSs, both adult and elderly users had a significantly higher intake than non-users. While proportions below Estimated Average Requirements for all micronutrients by adding respective DSs in users were significantly reduced in adults and elderly as compared to non-users, the proportions of above Tolerable Upper Intake Levels for calcium and vitamin A in adults, and vitamin A in elderly, were significantly increased. In the total subjects examined, consumption of DSs was associated with lower odds ratios of undernutrition of micronutrients, and with higher odds ratios of overnutrition of calcium, iron, and vitamin A, as compared to non-users of DSs. Conclusions: Although DSs consumption by adults and the elderly improves the micronutrient status, it also increases the risk of excessive intake of certain vitamins and minerals.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제19권1호
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• pp.44-53
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• 2016

Purpose: Parenteral nutrition (PN) not only provides nutritional support but also plays a crucial role in the treatment of children with intestinal failure. The aim of this study was to evaluate the clinical significance and clinical outcomes of long-term PN. Methods: Retrospective cohort study was conducted using the medical records of patients treated at Seoul National University Children's Hospital. This study included 19 patients who received PN for over six months. Most patients received home PN. Results: The indications for PN included short bowel syndrome, chronic intestinal pseudo-obstruction, and intractable diarrhea of infancy. The median age of PN initiation was 1.3 years, and the median treatment duration was 2.9 years. Two patients were weaned from PN; 14 continued to receive PN with enteral feedings; and 3 patients died. The overall survival rates at 2 and 5 years were 93.3% and 84.0%, respectively. The incidence of catheter-related bloodstream infections was 2.7/1,000 catheter-days and was associated with younger age at PN initiation and lower initial height Z-score. Six patients developed catheter-related central vein thrombosis, with an incidence of 0.25/1,000 catheter-days. Eleven patients experienced PN-associated liver disease (PNALD), and one patient underwent multi-visceral transplant. The patients with PNALD exhibited lower final heights and body weight Z-scores. All patients experienced micronutrient deficiencies transiently while receiving PN. Conclusion: PN is an important and safe treatment for pediatric intestinal failure. PNALD was linked to final anthropometric poor outcomes. Micronutrient deficiencies were common. Anthropometric measurements and micronutrient levels must be monitored for successful PN completion.

• 생물환경조절학회지
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• 제15권2호
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• pp.196-203
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• 2006

본 연구는 입상형 미량원소복합제가 혼합된 상토에 용과린의 시비량을 증가시킬 경우 매리골드 'Orange boy'의 플러그 묘 생육에 미치는 영향을 구명하기 위하여 수행하였다. 연구 목적을 달성하기 위하여 피트모스+부숙톱밥(1:1, v/v; PS), 피트모스+부속왕겨(1:1, v/v; PR) 및 피트모스+부숙수피(1:1, v/v; PB)의 세종류 상토에 조제된 미량원소복합제를 $0.3g{\cdot}L^{-1}$로 혼합한 후 용과린의 시비량을 달리하고, 파종 35일 후 지상부 생육을 조사하였다. PS상토에 용과린의 시비량을 증가시킬 경우 네 종류 미량원소복합제 모두 초장, 초폭, 줄기직경, 생체중 및 건물중이 증가하였다. 그러나 용과린을 $9.0g{\cdot}L^{-1}$로 시비한 경우 건물중이 MF 1은 0.066g, MF 2에서 0.103g, MF 3에서 0.077g, 그리고 대조구(micronutrient fertilizer)에서 0.095g으로 조사되어 미량원소복합제에 따른 차이를 확인할 수 있었다. PR 상토에 MF 1이 혼합된 경우 $9.0g{\cdot}L^{-1}$의 용과린 처리에서 건물중 및 생체중이 가장 무거웠고, MF 2에서는 $3.0g{\cdot}L^{-1}$ 처리에서, MF 3는 $9.0g{\cdot}L^{-1}$에서 그리고 대조구는 $6.0g{\cdot}L^{-1}$ 처리에서 생체중과 건물중이 가장 무거웠다. 미량원소복합제를 포함한 PB상토에서 용과린의 시비량을 증가시킬 경우 생체중 및 건물중이 증가하였고 대부분의 생육지표에서 직선 및 2차곡선회귀가 성립하여 경향이 뚜렷하였다. 그러나 용과린의 시비량은 $9.0g{\cdot}L^{-1}$로 조절한 경우 MF 1에서 0.131g, MF 2에서 0.104g, MF 3은 0.137g, 그리고 대조구에서 0.111g의 건물중을 생산하였고, MF 1과 MF 3이 MF 2나 대조구보다 작물 생육에 효과적이었다.

• Applied Biological Chemistry
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• 제44권4호
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• pp.240-245
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• 2001

본 연구에서는 키토산 화합물을 함유한 미량원소 엽면 살포제를 엽채류에 처리하여 질산태 질소 축적 저감 효과를 조사하였다. Ca, Cu, Mn, Mo, Zn 등의 무기영양원소에 키토산과 키토산올리고당을 각각 첨가한 2종류의 미량원소 액제를 온실조건에서 포트에 재배한 상추와 시금치에 정식 후 3주와 4주째에 엽면 살포하였다. 정식 후 5주째에 수확하여 생육량, 엽록소와 미량원소 함량 및 Brix 당도,그리고 질산태 질소와 질산환원효소 활성을 조사하였다. 엽면 살포 액제의 시용을 통하여 작물의 생육 촉진과 함께 질산태 질소의 축적을 10-23% 정도 저감시킬 수 있는 것으로 나타났다. 이러한 결과는 미량원소와 키토산 화합물의 흡수를 통하여 엽록소와 미량원소 함량이 증가되었고 결국 광합성을 비롯한 관련 대사과정들과 질산 환원효소의 활성을 증대시킬 수 있으며 따라서 동시에 질산의 축적을 저감시킬 수 있는 것으로 판단되었다. 이러한 엽면 처리를 통한 질산태 질소의 축적 저감 효과를 극대화하기 위해서는 엽면처리 미량원소의 종류와 함유 비율, 처리 농도, 처리 시기 및 회수의 최적화 등에 대한 검토와 연구가 더 이루어져야 할 것이며, 질소 시비량과 재배환경의 조절 측면의 연구와 대책 또한 동시에 마련되어야 할 것으로 보인다.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2005년도 춘계학술발표회 요지
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• pp.72-73
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• 2005

• 한국동물학회:학술대회논문집
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• 한국동물학회 2001년도 한국생물과학협회 학술발표대회
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• pp.219.2-220
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• 2001

No Abstract, See Full Text

• Asian-Australasian Journal of Animal Sciences
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• 제33권12호
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• pp.1885-1895
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• 2020

Vitamins and minerals categorized as micronutrients are the essential components of animal feed for maintaining health and improving immunity. Micronutrients are important bioactive molecules and cofactors of enzymes as well. Besides being cofactors for enzymes, some vitamins such as the fat-soluble vitamins, vitamin A and D have been shown to exhibit hormone-like functions. Although they are required in small amount, they play an influential role in the proper functioning of a number of enzymes which are involved in many metabolic, biochemical and physiological processes that contribute to growth, production and health. Micronutrients can potentially have a positive impact on bone health, preventing bone loss and fractures, decreasing bone resorption and increasing bone formation. Thus, micronutrients must be provided to livestock in optimal concentrations and according to requirements that change during the rapid growth and development of the animal and the production cycle. The supply of nutrients to the animal body not only depends on the amount of the nutrient in a food, but also on its bioavailability. The bioavailability of these micronutrients is affected by several factors. Therefore, several technologies such as nanoparticle, encapsulation, and chelation have been developed to improve the bioavailability of micronutrients associated with bone health. The intention of this review is to provide an updated overview of the importance of micronutrients on bone health and methods applied to improve their bioavailability.

• Clinical and Experimental Pediatrics
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• 제48권12호
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• pp.1295-1309
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• 2005

Nowadays, the nutritional deficits are rarely seen in Korea. However, an increased availability of the highly palatable energy dense, nutrient-poor foods increases the risks of obesity and deficits of vitamins and minerals in the general population. Also, optimum intake of vitamins and minerals, which varies with age and genetic back ground, might not suffice the poor, young, obese, and elderly people. Young girls and individuals participating in weight reductions and aesthetic components are prone to micronutrient deficiencies because they restrict food intake and specific micronutrient rich foods. An inadequate intake of vitamins or minerals is associated with reduced physical performance and exercise capacity, increased obesity, decreased cognitive function, increased DNA damages such as single- and double-stranded breaks or oxidative DNA lesions, and accelerated aging process and increased neuronal damages with mitochondrial oxidative decay. Most of these deleterious effects of the deficit could be prevented by a one tablet of multivitamins with a good balanced diet. High dose B vitamins are frequently administered to overcome the metabolic inadequacy to the people with the less functional enzymes with increased Km values for their coenzymes due to the single gene mutation or due to the single nucleotide polymorphisms. And some certain antioxidant vitamins are also used in large quantities to overcome the oxidative stress and to repair the damages. In this review, new nutritional concepts of some vitamins and minerals, which are widely used and useful for the children, will be discussed.

• Preventive Nutrition and Food Science
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• 제8권2호
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• pp.162-165
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• 2003

The enzyme activity and the micronutrient content of powdered raw meal (PRM) and powdered processed meal (PPM) were compared. PRM was made of freeze-dried cereals, fruits, and vegetables. PPM was made of the same materials as PRM, but with heat processing such as steaming, roasting and hot air drying. The activity of $\alpha$-amylase of PRM was higher than that of PPM. However there were no differences of the concentration of proximate components between PRM and PPM. The concentrations of vitamin A, C, folic acid, biotin, calcium, potassium, sodium and iron in PRM were higher than in PPM, but there were no differences in vitamins E, B$_1$, B$_2$, phosphorus and zinc. This research demonstrated that PRM retains greater nutritional value because there is higher enzyme activity and less loss of micronutrients during processing in PRM than in PPM.

• Journal of Digestive Cancer Research
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• 제1권2호
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• pp.82-88
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• 2013

Cancer is the first leading cause of death in Korea and the second leading cause of death in the USA. There is extensive research into prevention of cancer and the support of oncology patients with diet or dietary supplements. In vitro and in vivo animal studies have indicated that antioxidants, including beta-carotene, alpha-tocopherol, and ascorbic acid, can yield anti-cancer effects in addition to providing protection against oxidative damage. Although many observational studies have shown that consuming fruits and vegetables can reduce the risk of some cancers, the results of several large-scale human intervention trials testing the benefits of a single or combined higher-dose of individual micronutrients have been inconsistent. Cancer can cause profound metabolic and physiological changes which may affect patients' nutrient requirements. Although the optimal route of nutrient delivery is through diet, cancer patients often suffer symptoms that disrupt their food intake, including anorexia, premature satiety, altered taste and smell, and changes in bowel mobility. In particular, micronutrient deficits can slow postoperative healing, contribute to depression symptoms, and decrease immune competence. Cancer patients are generally motivated to take dietary supplements to improve responses to treatment and quality of life. The Physician's Health Study II (PHS II) randomized controlled trial reported recently that daily multivitamin supplementation significantly, albeit modestly, reduced the risk of total cancer. Although evidence of multivitamin use benefits is limited in cancer patients, taking dietary supplements with constituents in the range of the recommended daily allowance according to the Dietary Reference Intake (DRI) recommendation is generally considered to be safe.