• 대한생식의학회:학술대회논문집
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• 대한불임학회 2006년도 제51차 추계학술대회
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• pp.141-142
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• 2006

• Environmental Analysis Health and Toxicology
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• 제28권
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• pp.5.1-5.7
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• 2013

Objectives Despite increasing availability of global positioning system (GPS), no research has been conducted to analyze GPS data for exposure opportunities associated with time at indoor and outdoor microenvironments. We developed location-based and time-weighted spatial measures that incorporate indoor and outdoor time-location data collected by GPS. Methods Time-location data were drawn from 38 female subjects in California who wore a GPS device for seven days. Ambient standard deviational ellipse was determined based on outdoor locations and time duration, while indoor time weighted standard deviational ellipse (SDE) was developed to incorporate indoor and outdoor times and locations data into the ellipse measure. Results Our findings indicated that there was considerable difference in the sizes of exposure potential measures when indoor time was taken into consideration, and that they were associated with day type (weekday/weekend) and employment status. Conclusions This study provides evidence that time-location weighted measure may provide better accuracy in assessing exposure opportunities at different microenvironments. The use of GPS likely improves the geographical details and accuracy of time-location data, and further development of such location-time weighted spatial measure is encouraged.

• 한국산림과학회지
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• 제96권3호
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• pp.357-361
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• 2007

연구지는 6지역의 우수재배지역을 선정하여 기존에 재배활동을 하던 곳을 대상으로 조사하였다. 홍천, 상주, 진안, 풍기, 함양 그리고 상주인근의 밭인삼 재배지역을 조사지역으로 선정하였다. 각 지역별로 $20m{\times}20m$의 방형구를 선정하여 조사하였다. 월평균 기온은 산지인삼이 생육을 시작하는 5, 6월에는 상주지역의 온도가 가장 높았다. 그러나 7월과 8월의 온도는 함양과 홍천지역에서 가장 높은 것으로 나타났다. 홍천지역의 강수량은 생육과 관련 있는 6, 7월 무렵에도 다른 지역보다 높은 것을 알 수 있다. 풍기지역의 일사량은 5월과 6월이 다른 지역보다 높은 것을 알 수 있다. 모든 지역에서 광합성능력은 연령이 낮을수록 높은 경향을 보였다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집D
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• pp.648-653
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• 2001

This study represents the numerical analysis of natural convection of a microenvironments with a air permeability in the clothing air-layer. The clothing air layer of shoulder and arm was used for numerical analysis model. As a numerical analysis method, we adopted a finite volume method for two-dimensional laminar flow, and analyzed the flow and thermal characteristics of velocity, temperature and concentration in the air layer between body and clothing. As a temperature boundary conditions, we considered that a body skin has a high temperature with $34^{\circ}C$ the environmental temperatures are $5,\;15\;and\;25^{\circ}C$ for various permeability coefficients. The distributions of concentration, temperature and velocity were showed that two large cells were. formed at horizontal and vertical air layer, respectively. As the temperature difference between body skin and environment decrease, the heat transfer was decreased rapidly.

• 한국기계가공학회지
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• 제14권6호
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• pp.142-148
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• 2015

3D printing technology is a promising technique for fabricating complex 3D architectures based on the CAD/CAM system, and it has been extensively investigated to manufacture structures in the fields of mechanical engineering, space technology, automobiles, and biomedical and electrical applications. Recent advances in the 3D printing of soft structures have received attention for the application of the construction of flexible sensors of soft robotics or the recreation of tissue/organ-specific microenvironments. In this review paper, we would like to focus on delivering state-of-the-art fabrication of soft structures with 3D printing technology and its various applications.

• Biomolecules & Therapeutics
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• 제28권2호
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• pp.119-130
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• 2020

Changing trends in anticancer research have altered the treatment paradigm to the extent that it is difficult to investigate any anticancer drugs without mentioning immunotherapy. Thus, we are finally contemplating tumour regression using magic bullets known as immunotherapy drugs. This review explores the possible options and pitfalls in tumour regression by first elucidating the features of cancer and the importance of tumour microenvironments. Next, we evaluated the trends of anticancer therapeutics regulating tumour microenvironment. Finally, we introduced the concept of tumour regression and various targets of tumour microenvironment, which can be used in combination with current immunotherapy for tumour regression. In particular, we emphasize the importance of regulating the neurological manifestations of tumour microenvironment (N) in addition to inflammation (I) and hypoxia (H) in cancer.

• Journal of Photoscience
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• 제1권1호
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• pp.25-29
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• 1994

Diffuse reflectance and emission spectra of 7-hydroxyquinoline intercalated in the supercage of X and Y zeolites are compared with the absorption and emission spectra of aqueous 7-hydroxyquinoline solutions at various pH to understand protropic and photophysical properties of 7-hydroxyquinoline in zeolite microenvironments. Predominance of zwitterionic spedes with significant existences of the other three protropic equilibrium species, normal, protonated and deprotonated species in zeolite samples indicates that the major fraction of the molecules interact with strong acid and base sites of zeolite at an adsorbed position. Observed zeolite pHs of near neutrality are established by a near balance in numbers of many strong acid and base sites rather than by'small numbers or weakness of acid and base sites. Excitations of nonzwitterionic species such as deprotonated species also give prevailing zwitterionic fluorescence, indicating that excited and ground proton transfer cycles of protropic species can be triggered by photons in organized zeolite media as well as in water.

• Journal of Photoscience
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• 제4권1호
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• pp.1-5
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• 1997

A hitherto unknown diphenylbutadiene analog viz. 1-(p-N,N-dimethylaminophenyl)-4-phenyl-2-methyl-1E,3E-butadiene (10) has been prepared and its absorption, excitation, and fluorescent emission properties in different media including various organic solvents and aqueous bovine serum albumin (BSA) have been studied. For comparision, these properties have also been investigated for the parent diphenylbutadiene (2). Diene 10 exhibits solvent polarity/polarizability-sensitive fluorescence properties ($\lambda$$_{max}$, $\Phi$$_f$, $\tau$$_f$, K$_f$, f). It also binds to the hydrophobic domains of aqueous bovine serum albumin (BSA) with a binding constant of 3.89 x 10$^4$ M$^{-1}$. The relative fluorescence quantum yield of 10 increases, while, the fluorescence lifetime decreases with increasing concentration of-BSA. The results highlight the polar character of the singlet excited state of diphenylpolyenes and the utility of 10 as fluorescence probe for studying microenvironments of organized assemblies and biological supramolecular structures.

• The Korean Journal of Ecology
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• 제21권5_2호
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• pp.557-565
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• 1998

The occurrence and distribution of dictyostelid cellualr slime molds were investigated in forests of Mt. Paektu. Fourteen species were isolated from forest soils of thirteen sites as follows Dictyostelium minutum, D. brefeldianum, D. crassicaule, D. capitatum, D. mucoroides var. stoloniferum, D. macrocephalum, D. mucoroides, D. septentrionalis, D. purpureum, D. aureo-stipes, P. violaceum, P. pallidum and two unidentified speceis. Mean total clones and species found were 4,415.69 No./g and 2.92, respectively. Dominant species were D. minutum, D. brefeldianum and D. crassicaule in this study area, and first widespread species was D. minutum. All sepecies that found in Mt. Paektu were isolated from forests of South Korea. But dominant species was different from those of South Korea. Total clones and species were more in subalpine Eurya japonica than in low elevated abies nephrolepis. It was thought that distribution of dictyostelids was related to soil microenvironments by vegetation, not or not more elevation.

• BMB Reports
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• 제54권1호
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• pp.31-43
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• 2021

Dendritic cells (DC), which consist of several different subsets, specialize in antigen presentation and are critical for mediating the innate and adaptive immune responses. DC subsets can be classified into conventional, plasmacytoid, and monocyte-derived DC in the tumor microenvironment, and each subset plays a different role. Because of the role of intratumoral DCs in initiating antitumor immune responses with tumor-derived antigen presentation to T cells, DCs have been targeted in the treatment of cancer. By regulating the functionality of DCs, several DC-based immunotherapies have been developed, including administration of tumor-derived antigens and DC vaccines. In addition, DCs participate in the mechanisms of classical cancer therapies, such as radiation therapy and chemotherapy. Thus, regulating DCs is also important in improving current cancer therapies. Here, we will discuss the role of each DC subset in antitumor immune responses, and the current status of DC-related cancer therapies.