• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1989년도 가을 학술발표회 논문집
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• pp.65-70
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• 1989

Until recently post-processing of finite element model has been Heavily relied on expensive graphic peripheral devices. For this reason many engineers and researchers can not afford to access to the graphics. with the aid of inexpensive personal computers very econmical post-processor graphics program called MICRO-POST has been developed in conjunction with low-cost printers and plotters. Model geometry or results of analysis for the unlimitted meshes either produced by mainframe or microcomputer can be easily and economi-call presented in a number of different graphic devices. The paper presents the procedure obtaining the device the independent graphics, and the structure and functions of the program. It also describes a new error-preventive dialogue type input technique to control the plot operation in an interactive manner. Through the post-processing examples for the general purpose finite element programs, it demonstrates the usefulness of the program.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2009년도 추계학술대회 논문집
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• pp.132-136
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• 2009

The importance and interests for saving of energy and cost in industry has been steadily grown up. Therefore, process optimization to reduce the processing step and energy is one of the most important things. The micro-alloyed steel of which post-heat-treatment is not necessary, has attractive points for high strength materials. However, for the application of non-heat-treated steel to structural parts, it is necessary to confirm the reliability of mechanical properties. In order to estimate mechanical properties. The microstructure, hardness, tensile strength, compressive strength and tensile fatigue strength of micro-alloyed steel having 900MPa tensile strength has been investigated.

• BMB Reports
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• 제47권8호
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• pp.417-423
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• 2014

MicroRNAs (miRNAs) are a large family of post-transcriptional regulators, which are 21-24 nt in length and play a role in a wide variety of biological processes in eukaryotes. The past few years have seen rapid progress in our understanding of miRNA biogenesis and the mechanism of action, which commonly entails a combination of target degradation and translational repression. The target degradation mediated by Argonaute-catalyzed endonucleolytic cleavage exerts a significant repressive effect on target mRNA expression, particularly during rapid developmental transitions. This review outlines the current understanding of the mechanistic aspects of this important process and discusses several different experimental approaches to identify miRNA cleavage targets.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회A
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• pp.1469-1474
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• 2007

In recent years, research to machine large-surface micro-features has become important because of the light guide panel of a large-scale liquid crystal display and the bipolar plate of a high-capacity proton exchange membrane fuel cell. In this study, in order to realize the systematic design technology and performance improvements of an ultra-precision machine for machining the large-surface micro-features, a structural characteristic analysis was performed using its virtual prototype. The prototype consisted of gantry-type frame, hydrostatic feed mechanisms, linear motors, brushless DC servo motor, counterbalance mechanism, and so on. The loop stiffness was estimated from the relative displacement between the tool post and C-axis table, which was caused by a cutting force. Especially, the causes of structural stiffness deterioration were identified through the structural deformation analysis of sub-models.

• Asian Pacific Journal of Cancer Prevention
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• 제15권21호
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• pp.9059-9064
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• 2014

MicroRNAs (miRNAs) are ubiquitously expressed small, non-coding RNAs that negatively regulate gene expression at a post transcriptional/translational level. They have emerging as playing crucial roles in cancer at all stages ranging from initiation to metastasis. As a tumor suppressor miRNA, aberrant expression of microRNA-29b (miR-29b) has been detected in various types of cancer, and its disturbance is related with tumor development and progression. In this review, we summarize the latest findings with regard to the tumor suppressor signatureof miR-29b and its regulatory mechanisms. Our review highlights the diverse relationships between miR-29b and its target genes in malignant tumors.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7551-7554
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• 2013

Tumor-associated microRNAs have been detected in serum or plasma, but whether plasma microRNA-21 (miR-21) could be a potential circulating biomarker for gastric cancer (GC) prognosis in Chinese is still uncertain. Real-time quantitative reverse transcription PCR (qRT-PCR) was employed in this study to compare the relative expression of miR-21 between pre-operative and post-operative paired plasmas from 42 patients with primary GCs. The results showed that the expression levels of miR-21 in the post-operative plasmas were significantly reduced by an average of 18.2 times in all patients when compared to the pre-operative plasmas, and by 22.1 times in the subgroup of patients without family history, while only 1.76 times in the subgroup of patients with a family history. With respect of clinicopathological characteristics, the plasma miR-21 expression was highly associated with differentiation degree and lymph node metastasis rate. The results suggested plasma miR-21 could be a novel potential biomarker for GC prognosis and evaluation of surgery outcomes, especially in patients without a family history.

• International Journal of Computer Science & Network Security
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• 제21권12호
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• pp.335-343
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• 2021

The study aimed to elucidate how to design a learning environment on the premise of micro-learning (ML) and investigate its impact on website designing skills and achievement motivation among secondary school students. Adopting the experimental approach, data were collected through an achievement test, a product evaluation form, and a test to gauge motivation for achievement. The sample was divided into two experimental groups. Results revealed statistically significant differences at 0.05≥α between the mean scores of the two groups that experienced ML, irrespective of the two modes of presenting the video in the pre-test and post-test, as for the test of websites design skills, product evaluation form, and achievement motivation test. Besides, there have been statistically significant differences at 0.05≥α between the mean scores of the first experimental group that had exposure to ML using the split-video presentation style and the scores of the second experimental group that underwent ML using continuous video presentation style in the post cognitive test of website design and management skills in favor of the group that had segmented-video-presentation ML. Another salient finding is the nonexistence of significant differences at 0.05≥α between the mean scores of the first experimental group that underwent segmented-video-presentation ML and the grades of the second experimental group that received ML with continuous video presentation style in the post-application of the product scorecard of websites designing skills and the motivation test. In light of these salient findings, the study recommended using ML in teaching computer courses at different educational stages in Saudi Arabia, training computer and information technology teachers to harness ML in their teaching and using ML in designing courses at all levels of education.

• BMB Reports
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• 제49권6호
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• pp.311-318
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• 2016

Innate immune responses are primary, relatively limited, and specific responses to numerous pathogens and toxic molecules. Protein expression involved in these innate responses must be tightly regulated at both transcriptional level and post-transcriptional level to avoid the development of excessive inflammation that can be potentially harmful to the host. MicroRNAs are small noncoding RNAs (∼22 nucleotides [nts]) that participate in the regulation of numerous physiological responses by targeting specific messenger RNAs to suppress their translation. Recent work has shown that several negative regulators of transcription including microRNAs play important roles in inhibiting the exacerbation of inflammatory responses and in the maintenance of immunological homeostasis. This emerging research area will provide new insights on how microRNAs regulate innate immune signaling. It might show that dysregulation of microRNA synthesis is associated with the pathogenesis of inflammatory and infectious diseases. In this review, we focused on miR-146 and miR-125 and described the roles these miRNAs in modulating innate immune signaling. These microRNAs can control inflammatory responses and the outcomes of pathogenic infections.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2006년도 춘계학술대회 논문집
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• pp.143-144
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• 2006

In this paper, we proposed XP KMPR-1050 negative tone resist to replace SU-8 resist for multi-layer micro-structures and thick plating mold fabrication using UV-LIGA process. XP KMPR resist proposed in this paper can be easily striped using a common stripping solution such as NMP without damage of micro-structure. The conditions for the fabrication of XP KMPR micro-structure were optimized by adjustment of exposure and post-exposure bake(PEB). The $140{\mu}m$ -thick and an aspect ratio at least 10 micro-structure and multi-layer structures were successfully fabricated through the process conditions. Through-mold electroplating and PR striping of XP KMPR has been successfully demonstrated.

• Advances in nano research
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• 제9권3호
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• pp.147-156
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• 2020

This research is related to nonlinear stability analysis of advanced microbeams reinforced by Graphene Platelets (GPLs) considering generic geometrical imperfections and thermal loading effect. Uniform, linear and nonlinear distributions of GPLs in transverse direction have been considered. Imperfection sensitivity of post-bucking behaviors of the microbeam to different kinds of geometric imperfections have been examined. Geometric imperfection is first considered to be identical as the first buckling mode, then a generic function is employed to consider sine-type, local-type and global-type imperfectness. Modified couple stress theory is adopted to incorporate size-dependent behaviors of the beam at micro scale. The post-buckling problem is solved analytically to derive load-amplitude curves. It is shown that post-buckling behavior of microbeam is dependent on the type geometric imperfection and its magnitude. Also, post-buckling load can be enhanced by adding more GPLs or selecting a suitable distribution for GPLs.