• Title/Summary/Keyword: Micro wire

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Variation of Nephrotoxicity Biomarkers by Urinary Storage Condition in Rats

  • Lee, Jung-Min;Han, Young-Hwan;Choi, Su-Jeong;Park, Ju-Seong;Jang, Jeong-Jun;Bae, Re-Ji-Na;Lee, Mi Ju;Kim, Myoung Jun;Lee, Yong-Hoon;Kim, Duyeol;Lee, Hye-Young;Park, Sun-Hee;Park, Cheol-Beom;Kang, Jin Seok;Kang, Jong-Koo
    • Toxicological Research
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    • v.30 no.4
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    • pp.305-309
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    • 2014
  • Recently, there has been an increase in the use of several nephrotoxicity biomarkers in preclinical experiments. In addition, it has been indicated that the result may have been influenced by secondary factors, such as sample storage condition or storage period. In this study, we have assessed the variation in urinary nephrotoxicity biomarkers as a result of urine storage conditions and storage period of the urine. Urine was sampled from specific pathogen-free Sprague-Dawley rats (19 weeks old), which were housed individually in hanged stainless steel wire mesh cages. Urine was stored at $20^{\circ}C$, at $4^{\circ}C$, or at $-70^{\circ}C$ after sampling. The levels of the biomarkers such as beta-2 microglobulin (B2M), cystatin-C (Cys-C), N-acetyl-${\beta}$-D-glucosaminidase (NAG), micro albumin (MA), micro protein (MP) were measured at 6, 24, 48 and 144 hr after sampling. The B2M level was significantly decreased at 6, 24, 48, and 144 hr compared to 0 hr at $-70^{\circ}C$ (p < 0.05, p < 0.01, p < 0.05, and p < 0.05, respectively) and 24 and 144 hr at $20^{\circ}C$ (p < 0.01, p < 0.01, respectively). The Cys-C level was significantly decreased at 144 hr compared to 0 hr at $4^{\circ}C$ (p < 0.01), at $20^{\circ}C$ (p < 0.05) and at $70^{\circ}C$ (p < 0.01). MP and MA levels were not different for 144 hr in all storage conditions. Taken together, B2M and Cys-C levels were modulated by storage temperature and period. For the enhancement of test accuracy, it is suggested that strict protocols be established for samples to minimize the effects of the storage conditions on the detected levels of biomarkers.

A Study of Micro, High-Performance Solenoid-Type RF Chip Inductor (Solenoid 형태의 소형.고성능 RF Chip 인덕터에 대한 연구)

  • Kim, Jae-Uk;Yun, Ui-Jung;Jeong, Yeong-Chang;Hong, Cheol-Ho;Seo, Won-Chang
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.49 no.5
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    • pp.283-288
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    • 2000
  • In this work, small-size, high-performance simple solenoid-type RF chip inductors utilizing an Al2O3 core material were investigated. Copper (Cu) wire with $40\mum$ diameter was used as the coils and the size of the chip inductor fabricated in this work was $2.1mm\times1.5mm\times1.0mm$. The external current source was applied after bonding Cu coil leads to gold pads electro-plated on each end of backsides of a core material. High frequency characteristics of the inductance (L), quality factor (Q), and impedance (Z) of developed inductors were measured using an RF Impedance/Material Analyzer (HP4291B with HP16193A test fixture). This HP4291B was also used to obtain the equivalent circuit and its circuit parameters of the chip inductors. This HP4291B was also used to obtain the equivalent circuit and its circuit parameters of the chip inductors. The developed inductors have the self-resonant frequency (SRF) of 1.1 to 3.1 GHz and exhibit L of 22 to 150 nH. The L of the inductors decreases with increasing the SRF. The Z of the inductors has the maximum value at the SRF and the inductors have the quality factor of 70 to 97 in the frequency range of 500 MHz to 1.5 GHz.

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Development of Microscale RF Chip Inductors for Wireless Communication Systems (무선통신시스템을 위한 극소형 RF 칩 인덕터의 개발)

  • 윤의중;김재욱;정영창;홍철호
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.40 no.10
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    • pp.17-23
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    • 2003
  • In this study, microscale, high-performance, solenoid-type RF chip inductors were investigated. The size of the RF chip inductors fabricated in this work was 1.0${\times}$0.5${\times}$0.5㎣. The materials (96% Al2O3) and shape (I-type) of the core were determined by a Maxwell three-dimensional field simulator to maximize the performance of the inductors. The copper (Cu) wire with 40${\mu}{\textrm}{m}$ diameter was used as the coils. High frequency characteristics of the inductance (L), quality-factor (Q), and capacitance (C) of developed inductors were measured using an RF Impedance/Material Analyzer (HP4291B with HP16193A test fixture). The inductors developed have inductances of 11 to 39 nH and quality factors of 28 to 50 over the frequency ranges of 250MHz to 1 GHz, and show results comparable to those measured for the inductors prepared by CoilCraf $t^{Tm}$ that is one of the best chip inductor company in the world. The simulated data predicted the high-frequency data of the L, Q, and C of the inductors developed well.l.

A Bursty Traffics Friendly MAC Protocol in Wireless Sensor Networks (무선센서 네트워크에서 버스티 트래픽에 적합한 MAC 프로토콜)

  • Lee, Jin-young;Kim, Seong-cheol
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.22 no.5
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    • pp.772-778
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    • 2018
  • Due to the recent advances in computing, communication and micro-electromechanical technology, Wireless Sensor Networks (WSNs) applications have been extended from military to many commercial areas such as object tracking, wire detection, and vehicular sensor networks. In some applications bursty data from many sensor nodes may be generated and the generated data from the monitoring area may be sent in a limited time to the final destination, sink node. In this paper, we present a BTF-MAC protocol adequate for WSNs applications in which bursty data packets are required to be transmitted in a limited time. The BTF-MAC is a synchronous duty-cycle MAC protocol and uses a slot-reserved and operational period extension mechanism adapted to the traffics. Our numerical analysis and simulation results show that BTF-MAC outperforms other related protocols such as DW-MAC and SR-MAC in terms of energy consumption and transmission delay.

Wireless Sensor Network based Remote Power Monitoring System for Anti Islanding application in Smart-Grid (스마트 그리드 내 독립전원의 단독운전 방지를 위한 무선 센서 네트워크 기반의 원격 전력 감시 시스템)

  • Kim, Kee-Min;Lee, Kyung-Jung;Moon, Chan-Woo;Ahn, Hyun-Sik;Jeong, Gu-Min
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.10 no.4
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    • pp.57-62
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    • 2010
  • Renewable energy and smart grid become the focus of attention of industry. The smart grid is an intelligent system which maximizes the efficiency of energy and it needs to monitor the amount of power generation and power consumption continuously. Remote Monitoring System(RMS) is very useful for monitoring the power generation and consumption, but mostly they are implemented on the wire communication. In this paper, we propose a wireless sensor network based remote power monitoring system. And as an application, a new anti-islanding method with the proposed RMS is presented. An experimental micro grid system is implemented to verify the proposed RMS and anti-islanding method.

Effect of High Pressure of Voltammetric Parameters of Copper (구리의 전압전류법적 파라미터에 미치는 압력의 영향)

  • Zun Ung Bae;Heung Lark Lee;Hong Soon Park
    • Journal of the Korean Chemical Society
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    • v.33 no.4
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    • pp.399-405
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    • 1989
  • The dependence of voltammetric parameters on the pressure for the reduction of Cu(II) in 0.5M KCl aqueous solution has been studied. In this system micro platinum electrode, standard calomel electrode and a helix type of platinum wire were used as the working, the reference and the auxilary electrode, respectively. With increasing the pressure from 1 to 1,800 bars, the half wave potentials of first reduction wave are shifted to the more negative potentials. And the diffusion currents of first and second reduction wave become considerably larger with increase in pressure from 1 to about 1,000 bars but are getting smaller beyond 1,000 bars. The good linear relationships between diffusion current and the concentrations of Cu(II) are established over all pressure range($1{\sim}1,800$ bars). The reversibility of the each reduction step is not changed with increasing pressure.

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Electrochemical Characteristics in Sea Water of Al-3%Mg Arc Spray Coating Layer for Corrosion Protection with Sealing Treatment (후처리 적용에 따른 방식용 Al-3%Mg 용사코팅 층의 해수 내 전기화학적 특성)

  • Park, Il-Cho;Kim, Seong-Jong
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.40 no.5
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    • pp.974-980
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    • 2015
  • Arc thermal spray coating using Al-3%Mg thermal spray wire was carried out to prevent steel from corrosion damage under the marine environment. Post-sealing was applied to Al-3%Mg spray coating treatment using organic/inorganic composite ceramics in order to improve the corrosion resistance of the as-sprayed coating. The results of various electrochemical experiments with sealing treatment indicated that the improvement in corrosion resistance was observed due to low current density in all applied potential range during anodic and cathodic polarization experiments. Futhermore, the natural potential measurement exhibited severe potential fluctuation due to influence of micro-crack presence on the surface of sealed thermal spray coating layer. In addition, the sealed layer was easily eliminated during anodic polarization. Nevertheless, Al-3%Mg spray coating layer improved corrosion resistance by sealing treatment because the sealed coating efficiency was determined to be 92.11%, indicating the exterior environment barrier effect which is based on the Tafel analysis.

Fabrication of the Micromachined Transformer based on Air Core for the Application of Wireless Power Transmission (무선전력전송을 위한 에어 코어 기반의 트랜스포머 제작)

  • Kim, Sung-Tae;Cha, Doo-Yeol;Kang, Min-Suck;Cho, Se-Jun;Jang, Sung-Pil
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.22 no.1
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    • pp.1-6
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    • 2009
  • Air core based transformers have been designed, simulated and fabricated by using micromachining process for the application of wireless power transmission with the range of frequency from 1 GHz to 20 GHz. Fabricated transformers are the types of solenoid transformers with primary and secondary coils. the size of fabricated transformer is $1.1{\times}1.5{\sim}2.15\;mm$ including ground shield. Transformers have been measured by dividing two groups based on the turns ratio between primary coil and secondary coil which are 1:1 transformers(the number of turns of primary coil and secondary coil: 3/3, 5/5, 7/7) and l:n transformers(the number of turns of primary coil and secondary coil: 3/3, 3/6, 3/9). As a result of the measurement, the lowest insertion loss of transformers ranged from 2 dB to 2.8 dB according to the number of turns between primary coil and secondary coil. And the lowest insertion loss from the transformers was measured at the frequency from 7 GHz to 11 GHz according to the number of turns between primary coil and secondary coil. Based on the measurement data from the microfabricated transformers, the transformer with the 3/3 turns in the primary coil and secondary coil showed best performance compared to others in terms of lowest insertion loss, lowest insertion loss frequency and bandwidth.

Post-ischemic Time-dependent Activity Changes of Hippocampal CA1 cells of the Mongolian Gerbils

  • Won, Moo-Ho;Shin, Hyung-Cheul
    • The Korean Journal of Physiology and Pharmacology
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    • v.11 no.6
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    • pp.247-251
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    • 2007
  • Changes of single unit activity of CA1 hippocampus region were investigated in anesthetized Mongolian gerbils for six days following transient ischemia. Ischemia was produced immediately before the implantation of micro-wire recording electrodes. In control animals receiving pseudo-ischemic surgery, neither spontaneous neuronal activities ($5.70{\pm}0.4Hz$) nor the number of recorded neurons per animal changed significantly for six days. Correlative firings among simultaneously recorded neurons were weak (correlation coefficient > 0.6) in the control animals. Animals subjected to ischemia exhibited a significant elevation of neural firing at post-ischemic 12 hr ($9.95{\pm}0.9Hz$) and day 1 ($8.48{\pm}0.8Hz$), but a significant depression of activity at post-ischemic day 6 ($1.84{\pm}0.3Hz$) when compared to the activities of non-ischemic control animal. Ischemia significantly (correlation coefficient > 0.6) increased correlative firings among simultaneously recorded neurons, which were prominent especially during post-ischemic days 1, 2 and 6. Although the numbers of spontaneously active neurons recorded from control group varied within normal range during the experimental period, those from ischemic group changed in post-ischemic time-dependent manner. Temporal changes of the number of cells recorded per animal between control group and ischemic group were also significantly different (p = 0.0084, t = 3.271, df = 10). Cresyl violet staining indicated significant loss of CA1 cells at post-ischemic day 7. Overall, we showed post-ischemic time-dependent, differential changes of three characteristics, including spontaneous activity, network relationship and excitability of CA1 cells, suggesting sustained neural functions. Thus, histological observation of CA1 cell death till post-ischemic day 7 may not represent actual neuronal death.

Superhydrophobic nano-hair mimicking for water strider leg using CF4 plasma treatment on the 2-D and 3-D PTFE patterned surfaces

  • Shin, Bong-Su;Moon, Myoung-Woon;Kim, Ho-Young;Lee, Kwang-Ryeol
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.02a
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    • pp.365-365
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    • 2010
  • Similar to the superhydrophobic surfaces of lotus leaf, water strider leg is attributed to hierarchical structure of micro pillar and nano-hair coated with low surface energy materials, by which water strider can run and even jump on the water surface. In order to mimick its leg, many effort, especially, on the fabrication of nanohairs has been made using several methods such as a capillarity-driven molding and lithography using poly(urethane acrylate)(PUA). However most of those effort was not so effective to create the similar structure due to its difficulty in the fabrication of nanoscale hairy structures with hydrophobic surface. In this study, we have selected a low surface energy polymeric material of polytetrafluoroethylene (PTFE, or Teflon) assisted with surface modification of CF4 plasma treatment followed by hydrophobic surface coating with pre-cursor of hexamethyldisiloxane (HMDSO) using a plasma enhanced chemical vapor deposition (PE-CVD). It was found that the plasma energy and duration of CF4 treatment on PTFE polymer could control the aspect ratio of nano-hairy structure, which varying with high aspect ratio of more than 20 to 1, or height of over 1000nm but width of 50nm in average. The water contact angle on pristine PTFE surface was measured as approximately $115^{\circ}$. With nanostructures by CF4 plasma treatment and hydrophobic coating of HMDSO film, we made a superhydrophobic nano-hair structure with the wetting angle of over $160^{\circ}C$. This novel fabrication method of nanohairy structures has been applied not only on 2-D flat substrate but also on 3-D substrates like wire and cylinder, which is similarly mimicked the water strider's leg.

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