• Molecules and Cells
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• v.46 no.6
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• pp.351-359
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• 2023

Deamination of adenine or cytosine in RNA, called RNA editing, is a constitutively active and common modification. The primary role of RNA editing is tagging RNA right after its synthesis so that the endogenous RNA is recognized as self and distinguished from exogenous RNA, such as viral RNA. In addition to this primary function, the direct or indirect effects on gene expression can be utilized in cancer where a high level of RNA editing activity persists. This report identified actin-related protein 2/3 complex inhibitor (ARPIN) as a target of ADAR1 in breast cancer cells. Our comparative RNA sequencing analysis in MCF7 cells revealed that the expression of ARPIN was decreased upon ADAR1 depletion with altered editing on its 3'UTR. However, the expression changes of ARPIN were not dependent on 3'UTR editing but relied on three microRNAs acting on ARPIN. As a result, we found that the migration and invasion of cancer cells were profoundly increased by ADAR1 depletion, and this cellular phenotype was reversed by the exogenous ARPIN expression. Altogether, our data suggest that ADAR1 suppresses breast cancer cell mobility via the upregulation of ARPIN.

• Journal of the Korean Solar Energy Society
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• v.39 no.6
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• pp.93-112
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• 2019

In this paper, a very new web-based software for renewable energy system (RES) design and economic evaluation was introduced. This solution would provide the precise RES estimation service including not only photovoltaic (PV), wind turbine (WT) and fuel cell (FC) individually but also energy storage system (ESS) as combined forms with PV or WT. The three reasons why we ought to develop it are: First, the standardized tool suitable to the domestic environment for estimating power generation from RES facilities and economic evaluation is required. Secondly, the standardized tool is needed to spread domestic RES supply policy and to promote the new industry in the micro-grid field. The last, the reliability of economic evaluation should be enhanced more for new facilities. To achieve those aims, the weather database of one hundred locations have established and the RES facility database has also constructed. For the energy management, mathematical models for PV, WT, ESS and FC were developed. As a final phase, the analytical process to evaluate economics has performed with field data verification.

• Journal of Information Processing Systems
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• v.14 no.4
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• pp.989-1009
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• 2018

Rapid advances in science and technology with exponential development of smart mobile devices, workstations, supercomputers, smart gadgets and network servers has been witnessed over the past few years. The sudden increase in the Internet population and manifold growth in internet speeds has occasioned the generation of an enormous amount of data, now termed 'big data'. Given this scenario, storage of data on local servers or a personal computer is an issue, which can be resolved by utilizing cloud computing. At present, there are several cloud computing service providers available to resolve the big data issues. This paper establishes a framework that builds Hadoop clusters on the new single-board computer (SBC) Mobile Raspberry Pi. Moreover, these clusters offer facilities for storage as well as computing. Besides the fact that the regular data centers require large amounts of energy for operation, they also need cooling equipment and occupy prime real estate. However, this energy consumption scenario and the physical space constraints can be solved by employing a Mobile Raspberry Pi with Hadoop clusters that provides a cost-effective, low-power, high-speed solution along with micro-data center support for big data. Hadoop provides the required modules for the distributed processing of big data by deploying map-reduce programming approaches. In this work, the performance of SBC clusters and a single computer were compared. It can be observed from the experimental data that the SBC clusters exemplify superior performance to a single computer, by around 20%. Furthermore, the cluster processing speed for large volumes of data can be enhanced by escalating the number of SBC nodes. Data storage is accomplished by using a Hadoop Distributed File System (HDFS), which offers more flexibility and greater scalability than a single computer system.

• 제어로봇시스템학회:학술대회논문집
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• 1997.10a
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• pp.828-831
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• 1997

One of the most important design factor for the image tracker is the speed of the data processing which allows real-time operation of the system and provides reasonably accurate performance at the same time. Use of powerful DSP alone does not guarantee to meet such requirement. In this paper, a simple efficient algorithm for real-time multi-target image tracking is suggested. The suggested method is based on a recursive centroiding technique and color table look-up. This method has been successfully implemented in a image processing system for Micro-Robot Soccer Tournament(MIROSOT). This tracker can track positions of a ball, 3 enemies, and 3 agents at the same time. The experimental results show that the processing time for each frame of image is less than 7ms, which is well within the 60Hz sampling interval for real-time operation.

• International Journal of Contents
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• v.16 no.2
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• pp.30-40
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• 2020

This study performed GIS and statistical analyses on the location and spatial characteristics of the slum in Daejeon. Spatial data of 648 slum residents in Daejeon were collected and 131 residents among them were surveyed. The results showed the trends of higher rent, lower social exclusion and closer neighboring relations in slum center than the surrounding areas, which could be interpreted as the interrelated multilateral effects of the micro- (housing), meso- (relations), exo- (community) and macro- (government policy) systems. The strong bonds among neighbors and various supports from social service facilities elevated the slum area's rent and diminished residents' social exclusion more than housing conditions (for instance, poor hygiene and low safety). Slum tenants willingly paid a premium for their substandard housings and refused moving to governmentally provided modern housing units. In urban development, administrative authorities need to be cautious about slum uprooting. Much rather an alternative renewal approach is needed which protects the slum's intimate relations while improving its overall living standards.

• Journal of the korean Society of Automotive Engineers
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• v.7 no.3
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• pp.64-73
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• 1985

In order to control ignition advance angle, this system is designed with Z-80 CPU, CTC (counter Timer Circuit), PIO(Parallel Input Output), A/D Converter and Memory, etc. Serial pulses from speed sensor and analog voltage from pressure sensor are converted to digital data. In order to reduce the error of ignition advance angle output, the reference of ignition advance angle output is set 56.25 before TDC(Top Dead Center). The table of ignition advance angle and program which have a main routine and subroutines are written into ROM ( 1 K-byte). The experimental result of this system is correspondent to the theoretical values of proposed ignition advance angle table. This system can be utilized to any other type of 4 cylinder vehicles for advance angle control by changing software.

• Journal of Mechanical Science and Technology
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• v.19 no.2
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• pp.649-654
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• 2005

This paper presents fabrication and drive test of a peristaltic PDMS micropump actuated by the thermopneumatic force. The micropump consists of the three peristaltic-type actuator chambers with microheaters on the glass substrate and a microchannel connecting the chambers and the inlet/outlet port. The micropump is fabricated by the spin-coating process, the two-step curing process, the JSR (negative PR) molding process, and etc. The diameter and the thickness of the actuator diaphragm are 2.5 mm and $30{\mu}m$, respectively. The meniscus motion in the capillary tube is observed with a video camera and the flow rate of the micro pump is calculated through the frame analysis of the recorded video data. The maximum flow rate of the micropump is about $0.36\;{\mu}L/sec$ at 2 Hz for the zero hydraulic pressure difference when the 3-phase input voltage is 20 V.

• Journal of the Korean Society for Precision Engineering
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• v.26 no.11
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• pp.35-40
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• 2009

This paper presents the geometrical analysis of an inclined ultra-precision grinding technology using simulations about grinding point locus for micro lens manufacturing. Simulation results show the relationship between radius ratios ($R_1/R_2$) and wheel center locus. Furthermore, the critical grinding wheel radius ($R_1$) can be calculated from work-piece radius ($R_2$) and inclined angle ($\theta=-45^{\circ}$). These achievements could be applied to calculate CNC data in ultra-precision grinding and give insight for wheel wear and compensation grinding.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.55 no.4
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• pp.371-378
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• 2010

For sensitive and accurate gene expression analysis, normalization of gene expression data against housekeeping genes is required. There are conventional housekeeping gene (e.g. ACT) that primarily function as an internal control of transcription. In this study, we performed an in silico analysis of 278 rice gene expression samples (GSM) in order to identify the gene that is most consistently expressed. Based on this analysis, we identified novel candidate housekeeping genes that displayed improved stability among the cross experimental conditions. Furthermore four of the most conventional housekeeping genes were included in our 30 other housekeeping genes among the most stable genes. Therefore, these 30 genes can he used to normalize transcription results in gene expression studies on rice at a broad range of experimental conditions.

• Journal of Korean Medicine Rehabilitation
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• v.30 no.1
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• pp.63-78
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• 2020

Objectives To review the epigenetic modifications involved in chronic pain and to improve individualized intervention for the chronic pain. Methods Focused literature review. Results Significant laboratory and clinical data support that epigenetic modifications have a potential role for development of chronic pain. Conclusions Epigenetic approach may identify mechanisms critical to the development of chronic pain after injury, and may provide new pathways and target mechanisms for future treatment and individualized medicine.