• 한국전문물리치료학회지
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• 제16권3호
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• pp.50-59
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• 2009

The aim of the study was to evaluate the effectiveness of exercise therapy on physical function of patients with anklyosing spondylitis (AS) through the systemic review and meta-analysis. The 54 studies were identified from computerized search of published researches on PubMed, Embase, CINAHL, PEDro, KISS, KERIS database until February, 2008 and review of reference lists. The main search terms were the combination "ankylosing spondylitis", "exercise", "spondyloarthropathy and exercise", "ankylosing spondylitis and physical therapy". The subgroup analysis was performed by the publication year, quality score, type of disease, content of intervention, intervention provider, type of intervention, method of intervention, intervention period and the point of outcome measured. Two reviewers independently selected trials for inclusion, assessed the quality and extracted the data. The result was as follows: The 10 trials were eligible for inclusion criteria, then the systematic review and meta-analysis was assessed on effectiveness of exercise therapy. The meta-analysis of 10 studies based on the random effect model showed that the exercise therapy was beneficial in treating the diseases (effect size .55; 95% confidence interval -.3.75~.61). The findings suggest that the exercise therapy would be appropriate to manage the physical function of AS with evidence based on Meta-analysis. Therefore, the exercise therapy supervised by physical therapist should be recognized as the essential approach to manage the AS and necessarily recommended to improve physical function.

• Industrial Engineering and Management Systems
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• 제11권3호
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• pp.288-298
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• 2012

Lot sizing and shipment scheduling are two interrelated decisions made by a manufacturing plant and a third-party logistics distribution center. This paper analyzes a dynamic inbound ordering problem and shipment problem with a freight container cost, in which the order size of multiple products and single container type are simultaneously considered. In the problem, each ordered product placed in a period is immediately shipped by some freight containers in the period, and the total freight cost is proportional to the number of containers employed. It is assumed that the load size of each product is equal and backlogging is not allowed. The objective of this study is to simultaneously determine the lot-sizes and the shipment schedule that minimize the total costs, which consist of production cost, inventory holding cost, and freight cost. Because the problem is NP-hard, we propose three meta-heuristic algorithms: a simulated annealing algorithm, a genetic algorithm, and a new population-based evolutionary meta-heuristic called self-evolution algorithm. The performance of the meta-heuristic algorithms is compared with a local search heuristic proposed by the previous paper in terms of the average deviation from the optimal solution in small size problems and the average deviation from the best one among the replications of the meta-heuristic algorithms in large size problems.

• 부모자녀건강학회지
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• 제22권1호
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• pp.30-42
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• 2019

Purpose: This study was a systematic review and meta-analysis designed to evaluate the effects of breastfeeding individual visit program. Methods: Based on the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA), a systematic search was conducted using four core electronic databases from October 28, 2018 to November 14, 2018. The topics of breastfeeding individual visit program were analyzed using descriptive analysis and the effects of intervention were meta-analyzed using the Review Manager 5.3 software. Results: A total of 13 studies were included in the review and 12 were included for meta-analysis. Breastfeeding individual visit programs were found to be more effective in breastfeeding rates, attitude, skill and self-efficacy compared to group education or non-education. Conclusion: Effective breastfeeding education can help mothers to start and sustain breastfeeding. Breastfeeding individual visits programs that are more effective than group education to maintain breastfeeding for pregnant women should be developed and applied.

• 한국간호교육학회지
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• 제29권3호
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• pp.203-224
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• 2023

Purpose: This study aimed to evaluate the effectiveness of simulation-based education on communication and clinical judgment in nursing students and nurses. Methods: A systematic review and meta-analysis were conducted in accordance with the PRISMA guidelines. Seven databases were searched to obtain articles published in Korean or English. Of 12,864 articles reviewed, 36 were included in a systematic review and 23 in a meta-analysis. To estimate the size of the effects of simulation-based education, a meta-analysis was performed using the R package meta program. The risk of bias was assessed using RoB 2.0 and ROBINS-I. Results: The effect sizes (ES) of simulation-based education on communication and clinical judgment were ES=0.77, 95% confidence interval (95% CI)=0.43 to 1.12 on communication-related variables and ES=1.84, 95% CI=1.03 to 2.65 on clinical judgment. Conclusion: Simulation-based education for nursing students and nurses is useful for improving their communication and clinical judgment. Thus, it is necessary to develop and apply simulation-based education programs for nursing students and nurses to improve their abilities in communications and clinical judgment.

• International Journal of Internet, Broadcasting and Communication
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• 제15권4호
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• pp.185-190
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• 2023

With the continuous development of the game field, the subdivision of game types is becoming more and more precise. There are also more and more games that draw on some achievements in other fields in their game design. Among them are meta-fiction games based on metafiction. This article will explore whether the combination of a meta-fiction game and a side-scrolling game with a unique visual experience is appropriate. If the side-scrolling game is the external form of the game, then the meta-fiction game is the internal content core of the game. The degree of fit between the external form and the internal core will undoubtedly determine the lower limit and upper limit of the game quality. Based on alienation theory, this article takes several highly rated side-scrolling games on the market as examples to conduct a theoretical analysis on the compatibility of side-scrolling games and metafiction games. The analysis results suggest that compared to first-person games, side-scrolling games with a unique third-person perspective have the best compatibility with meta-games.

• 경영과학
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• 제31권2호
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• pp.33-48
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• 2014

It is important to maintain on operational availability of aircraft during wartime. The KF-16 fighter, the backbone of the ROKAF (Republic Of Korea Air Force), has a single engine. Therefore, the engine has a critical influence on operational availability. The purpose of this study is to estimate optimal levels of spare part inventories concerning both engines and modules. That is provided by linear programming methods utilizing a developed meta-model. For drawing out the meta-model, we develop a simulation model which can consider wartime demands. In the previous study, $2^k$ factorial design method is used to check the influence of each independent variable. That method requires relatively many scenarios because every extreme value combination of independent variables should be checked. However, this study adopts NOLH (Nearly Orthogonal Latin Hypercube) as an experimental design. By adopting NOLH, this study increases not only efficiency but also accuracy. That is proven by comparing the validity of the developed meta-model on both experimental designs. This study also utilizes the OptQuest simulation tool in ARENA to derive the optimal level of spare stocks. By comparing the result of OptQuest to that of the developed meta-model, the validity of this study is secured.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.323-335
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• 2016

Breast cancer risk assessment has developed during years and evaluation of genetic factor affecting risk of breast cancer is an important component of this risk assessment. The aim of this meta-analysis was to investigate the role of XRCC1 polymorphisms (Arg194Trp, Arg280His and Arg399Gln) in risk of breast cancer among different population and categories of menopausal status.PubMed, Medline, Web of Science, and PubMed Central were systematically searched to identify studies evaluating association between breast cancer and XRCC1 gene polymorphisms (Arg194Trp, Arg280His and Arg399Gln). Two authors independently extracted required information. Odds Ratios were pooled for four genetic inheritance models using both fixed and the DerSimonian and Laird random-effect models. Egger's test and contour-enhanced funnel plot was used to evaluate publication bias and small study effect. Additional subgroup analysis was performed for menopausal status, ethnicity, and source of controls. After evaluation and applying inclusion criteria on extracted studies, fifty three studies were included in this meta-analysis. For polymorphisms of Arg194Trp and Arg280His, no significant association was observed in all genetic models. Arg194Trp had a protective effect in post-menopausal status only in homozygote model (OR=0.57 [0.37-0.88]). Arg399Gln showed significant association with breast cancer in homozygote (OR=1.21 [1.10-1.34]), dominant (OR=1.09 [1.03-1.15]) and recessive (OR=1.21 [1.09- 1.35]) genetic models. Arg399Gln was associated with higher risk in post-menopausal status for homozygote and heterozygote models. Our findings suggest that XRCC1 gene polymorphisms modify breast cancer risk in different populations and different categories of menopausal status.

• 한국초등수학교육학회지
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• 제23권1호
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• pp.59-74
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• 2019

기존 이론적 연구에 의하면 메타정의적 능력은 학생의 정의적 요소로 하여금 수학 문제해결 과정에 긍정적으로 작용하게 만들어 성공적인 문제해결로 귀결됨을 알 수 있다. 이러한 인과성에 대한 실제적인 파악을 위하여 본 연구에서는 메타정의적 요소가 문제해결 활동에 작용하는 과정에서 구체적으로 보이는 특성을 알 수 있도록 수학 영재아들의 문제해결 과정에 나타나는 메타정의를 문제해결의 성공 여부에 따라 비교 분석하였다. 이를 위해 초등학교 4~6학년 수학 영재아를 소집단으로 구성하여 협업적 문제해결 상황에서 수집한 자료에 대하여 메타정의의 유형과 빈도를 분석하였다. 그 결과 수학 영재아의 문제해결 과정에 나타난 메타정의 유형은 문제의 정답률과 긴밀한 관련성이 있음을 알 수 있었다. 우선, 문제해결의 성공 여부와 관계없이 메타정의는 문제해결의 맥락과 관련된 인지적 요소가 먼저 나타나는 메타정의 유형들이 상대적으로 빈번하게 나타났으며, 평가 및 태도 유형의 메타적 기능으로 활발하게 작용하였다. 특히 수학 영재아의 성공적인 문제해결의 경우 메타정의는 평가 유형의 메타적 기능으로 매우 활발하게 작용하는 특성을 나타냈다. 이와 같은 수학 영재아의 문제해결 과정에 작용하는 메타정의의 특성은 수학 영재아의 수학 문제해결 상황을 성공적으로 이끌기 위한 구체적인 지도방법 구안에 기초를 제공할 것으로 생각한다.

• 헤리티지:역사와 과학
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• 제44권4호
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• pp.130-141
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• 2011

본 연구에서는 넓은 pH영역에서도 증점효과를 가지는 카보풀 수지 940, 934를 가지고 중화제(sodium meta silicate, triethylamine)별 겔을 제조하여 10% 과산화요소를 첨가하고, 이에 따른 표백효과를 알아보았다. 실험 결과 메타규산나트륨(sodium meta silicate) 1.6g을 첨가한 실험군에서 표백효과의 최적 조건인 pH 10을 충족시키고 있다. 또한 각군별 대조군 Baseline 색 변화량(${\Delta}E*ab$)과 시간별 색 변화량(${\Delta}E*ab$)을 비교해 보면 1군(카보풀 940, 메카규산나트륨, 과산화요소)은 CS-2에서 112%, CS-4는 63.3%, CS-6은 87.4%의 표백효율을 나타냈으며, 2군(카보풀 934, 메카규산나트륨, 과산화요소; CS-8, CS-10, CS-12)에서는 순서대로 77.3%, 67.3%, 109.%로 나타났다. 그리고 3군(카보풀 940, 트리에탄올아민, 과산화요소;CT-1, CT-3, CT-5)에서 36.8%, 73.2%, 74% 순으로, 4군(카보풀 934, 트리에탄올아민, 과산화요소; CT-6, CT-8, CT-10)에서는 81.7%, 95.4%, 95.7%의 표백효율을 보였다. 따라서 중화제 비율이 증가함에 따라 표백표율이 높아지는 것을 알 수 있었으며 메타규산나트륨을 중화제로 첨가한 것보다 트리에탄올을 중화제로 첨가한 것이 표백효율이 다소 높은 것을 알 수 있었다. 그러나 실험에 사용된 겔의 점도는 메타규산나트륨을 첨가한 군에서 점도가 트리에탄올아민을 첨가한 겔보다 높았다. 이는 유약이 시유된 경사진 도자기 표면에 표백겔이 흐르지 않고 부착되는 장점이 될 수 있다. 그러므로 10% 과산화요소 표백겔을 만들고자 할 때 메타규산 나트륨을 첨가하면 증점효과와 원하는 표백효과를 얻을 수 있을 것으로 판단된다.

• 한국정보과학회논문지:소프트웨어및응용
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• 제36권6호
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• pp.498-507
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• 2009

프로그래밍 언어 학습이 논리적 사고력에 미치는 영향에 대한 선행 연구는 부족한 실정이며, 각 연구 결과마다 연구 대상, 방법과 학습 주제 등에 따라 논리 향상 정도와 영역이 다르므로, 일반화 과정에 어려움이 있다. 또한 논리적 사고력의 향상이 학습자의 인지 발달에 의한 것인지 프로그래밍 언어 학습에 의한 것인지 분명하지 않아 프로그래밍 언어 학습의 필요성이 증명되었다고 할 수 없다. 본 연구에서는 초등 6학년생들에게 교육용 프로그래밍 언어 학습을 7차시 동안 실시한 후, 메타인지 수준별로 논리적 사고력에 미치는 영향을 조사하고, 컴퓨터 활용 교육의 효과와 비교하였다. 실험 결과에 따르면, 두리틀과 로고, 그리고 파워포인트 학습 집단 모두에서, 상위 수준의 메타인지를 지닌 학생들은 논리적 사고력에 유의미한 신장 효과를 나타낸 반면, 하위 수준의 학생들은 두리틀과 로고 학습 후에만 유의미한 논리적 사고력의 신장을 나타냈다. 그러나 메타인지 수준에 상관 없이 세 학습 집단 간에 논리적 사고력 향상 정도의 유의미한 차이는 없었다.