• Title/Summary/Keyword: Meta Evaluation

Search Result 357, Processing Time 0.026 seconds

Calcium hydroxide intracanal medication effects on pain and flare-up: a systematic review and meta-analysis

  • Ibrahim, Ahmed Mohamed;Zakhary, Siza Yacoub;Amin, Suzan Abdul Wanees
    • Restorative Dentistry and Endodontics
    • /
    • v.45 no.3
    • /
    • pp.26.1-26.18
    • /
    • 2020
  • Objectives: This study aimed to systematically review the pain and flare-up effects of calcium hydroxide (CH) as intracanal medication (ICM) in non-vital mature teeth. Materials and Methods: Electronic-databases searching for published and grey literature and manual searching were conducted. Only randomized clinical trials (RCTs) were included comparing CH to other ICMs in non-vital mature teeth. The risk of bias was assessed using the RoB 2.0 Cochrane tool. The main outcomes were pain and flare-up. Qualitative and quantitative analysis, wherever applicable, was performed. The certainty of evidence (CoE) was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE). Results: Sixteen articles were included in 6 comparisons at different time points for different outcomes. CH reduced pain risk than no ICM within the 1-14-days interval (p < 0.05) and than triple-antibiotic paste within the first day (p < 0.05) and was similar to corticosteroid/antibiotics combination (p > 0.05). Chlorhexidine (CHX) or CH/CHX, however, reduced pain levels than CH alone (p < 0.05). CH showed higher flare-up risk than CHX (p < 0.05). CoE, however, ranged from very low to moderate. Conclusion: Most comparisons for different outcomes are based on very few studies, mostly low-powered, with an overall low CoE. Thus, the available evidence is considered insufficient to either support or refute CH effectiveness or to recommend one ICM over another. Therefore, further well-designed, larger RCTs are required.

The global prevalence of Toxocara spp. in pediatrics: a systematic review and meta-analysis

  • Abedi, Behnam;Akbari, Mehran;KhodaShenas, Sahar;Tabibzadeh, Alireza;Abedi, Ali;Ghasemikhah, Reza;Soheili, Marzieh;Bayazidi, Shnoo;Moradi, Yousef
    • Clinical and Experimental Pediatrics
    • /
    • v.64 no.11
    • /
    • pp.575-581
    • /
    • 2021
  • Background: Toxocariasis is a zoonotic parasitic disease caused by Toxocara canis and Toxocara cati in humans. Various types of T. canis are important. Purpose: The current study aimed to investigate the prevalence of Toxocara spp. in pediatrics in the context of a systematic review and meta-analysis. Methods: The MEDLINE (PubMed), Web of Sciences, Embase, Google Scholar, Scopus, and Cumulative Index of Nursing and Allied Health databases were searched to identify peer-reviewed studies published between January 2000 and December 2019 that report the prevalence of Toxocara spp. in pediatrics. The evaluation of articles based on the inclusion and exclusion criteria was performed by 2 researchers individually. Results: The results of 31 relevant studies indicated that the prevalence of Toxocara spp. was 3%-79% in 10,676 cases. The pooled estimate of global prevalence of Toxocara spp. in pediatrics was 30 (95% confidence interval, 22%-37%; I2=99.11%; P=0.00). The prevalence was higher in Asian populations than in European, American, and African populations. Conclusion: Health policymakers should be more attentive to future research and approaches to Toxocara spp. and other zoonotic diseases to improve culture and identify socioeconomically important factors.

Framework for Assessing Maturity of Future Manufacturing System (미래 제조시스템 성숙도평가 프레임워크)

  • Lee, Jeongcheol;Chang, Tai-Woo;Park, Jong-Kyung;Hwang, Gyusun
    • The Journal of Society for e-Business Studies
    • /
    • v.24 no.2
    • /
    • pp.165-178
    • /
    • 2019
  • In an environment transformed by smart factories, measuring the current level of the manufacturing system, deriving improvement targets and tasks and increasing the level of manufacturing competitiveness become the basic activities of the company. However, research on the component analysis and maturity assessment to ensure the future competitiveness of the company is in progress and in the early stages. This study analyzed the existing research on various models, development process, and framework for manufacturing system. In addition, we designed a structural model by deriving the components of future manufacturing system through smart factory related maturity assessment studies. We designed a meta-model that includes an assesment model and a transformation model, and derived the framework development process to propose an integrated framework for the maturity assessment of the future manufacturing system. We verified it by applying it into an actual evaluation project of smart factory.

A Systematic Review and Meta-Analysis of Fire Needling Treatment for Knee Osteoarthritis: Focused on Comparative Studies with Manual Acupuncture Treatment during Recent Five Years (퇴행성 슬관절염의 화침 치료에 대한 체계적 문헌 고찰 및 메타분석: 최근 5년간의 호침 치료 비교 연구를 중심으로)

  • Ko, Hong-Je;Yoo, Jae-Hee;Shin, Jeong-Cheol
    • Korean Journal of Acupuncture
    • /
    • v.36 no.2
    • /
    • pp.104-114
    • /
    • 2019
  • Objectives : The purpose of this study is to review the effectiveness of fire needling treatment for knee osteoarthritis in comparison with manual acupuncture treatment. Methods : Through four foreign online databases (PubMed, Cochrane library, EMBASE, and CNKI) and five domestic online databases (NDSL, RISS, KISS, OASIS, and KTKP), we searched for clinical studies that performed fire needling treatment for knee osteoarthritis until May 10, 2019. Only randomized controlled trials were selected and we assessed the risk of bias according to the Cochrane RoB criteria. This review examined the selected studies into first author, publication year, sample size, outcome measurements, results, acupoints, treatment time & period and so on. Results : A total of 7 RCTs were selected in this review and all were conducted in China. Treatment period of more than 4 weeks and treatment visits of 10 to 20 times were the most common. EX-LE4 and ST35 (=EX-LE5) acupoints were most frequently selected in treatment. Among the evaluation indexes, a total efficacy rate was used the most. Most of fire needling groups showed more significant results compared with the manual acupuncture groups statistically. Conclusions : All studies showed that fire needling treatments for knee osteoarthritis were more effective than manual acupuncture treatments statistically. Therefore, the results of this study could be utilized as a preliminary data for another clinical research on fire needling treatment for knee osteoarthritis. However, further well-designed randomized controlled trials will be needed to develop sufficient evidence about the effectiveness and safety of fire needling treatment for knee osteoarthritis in the future.

Herbal Medicine for The Treatment of Pityriasis rosea: A Systematic Review and Meta-analysis (장미색 비강진의 한방 탕약 치료에 대한 연구 : 체계적 문헌 고찰)

  • Jin, Han-Sol;Lim, Hui-Yeong;Ko, Woo-Shin;Yoon, Hwa-Jung
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
    • /
    • v.34 no.4
    • /
    • pp.117-133
    • /
    • 2021
  • Objectives : Pityriasis rosea is an acute and subacute papular scaly disease, and is a disease that mainly resolves spontaneously. However, since the outbreak of COVID-19, the possibility that the disease may occur as a sequelae of the disease and side effects of vaccination has been announced. Methods : We searched articles related to oriental treatment of pityriasis rosea at organized in domestic and foreign DBs. Articles were searched for RCT. The results were summarized in tables and graphs, and meta-analysis was performed. Also, we assessed the risk or bias. Results : As a result of setting the herbal medicine alone treatment as an intervention for pityriasis rosea and Western medicine alone as the control group, total 9 articles were searched. We analyzed them and got the results. The efficient rate of the treatment group was statistically significantly higher than that of the control group. In addition, adverse events were significantly less in the treatment group than in the control group. Conclusions : Herbal medicine treatment can be more effective than Western therapy(mainly anti-histamines and glycyrrhizin injection) for pityriasis rosea. In addition, herbal medicine treatment can be superior to Western treatment for safety. However, the limitations of this study include the small number of articles, no other evaluation indicators other than the efficient rate, and insufficient data such as pathological examination.

A Tabu Search Algorithm for Network Design Problem in Wireless Mesh Networks (무선 메쉬 네트워크에서 네트워크 설계 문제를 위한 타부 서치 알고리즘)

  • Jang, Kil-woong
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.24 no.6
    • /
    • pp.778-785
    • /
    • 2020
  • Wireless mesh networks consist of mesh clients, mesh routers and mesh access points. The mesh router connects wireless network services to the mesh client, and the mesh access point connects to the backbone network using a wired link and provides Internet access to the mesh client. In this paper, a limited number of mesh routers and mesh access points are used to propose optimization algorithms for network design for wireless mesh networks. The optimization algorithm in this paper has been applied with a sub-subscription algorithm, which is one of the meta-heuristic methods, and is designed to minimize the transmission delay for the placement of mesh routers and mesh access points, and produce optimal results within a reasonable time. The proposed algorithm was evaluated in terms of transmission delay and time to perform the algorithm for the placement of mesh routers and mesh access points, and the performance evaluation results showed superior performance compared to the previous meta-heuristic methods.

Acupuncture for Symptomatic Rotator Cuff Disease: A Systematic Review and Meta-Analysis

  • Choi, Seoyoung;Lee, Jisun;Lee, Seunghoon;Yang, Gi Young;Kim, Kun Hyung
    • Journal of Acupuncture Research
    • /
    • v.38 no.1
    • /
    • pp.20-31
    • /
    • 2021
  • The objective was to evaluate the effectiveness and safety of acupuncture for patients with rotator cuff diseases. There were 12 electronic databases and 3 trial registries searched up to November 30th, 2019. All randomized trials were eligible, regardless of language, date of publication, or settings. The primary outcomes were pain, shoulder function, and proportion of improved participants assessed within 12 weeks of randomization of the trial. The Cochrane risk of bias for the studies was assessed. Effects sizes were presented as a risk ratio, mean difference, or standardized mean difference with a 95% confidence intervals. Grading of Recommendations Assessment, Development and Evaluation approach was adopted to rate certainty of evidence. Of the 3,686 records screened, 28 randomized trials (2,216 participants) were included in this review. The types of acupuncture included manual acupuncture, dry needling, electroacupuncture, acupotomy, warm needle acupuncture, and fire needle acupuncture. All of the studies had an unclear or high risk of bias related to more than 1 domain. Significant benefits of acupuncture in terms of pain and shoulder function were observed in all comparisons, however, the proportion of improved participants was not described in 2 comparisons. There was substantial heterogeneity among meta-analyzed trials. No serious harm was observed. For primary outcomes, the overall certainty of evidence was very low. There was very low certainty of evidence for the benefits of acupuncture for patients with rotator cuff diseases. The safety of acupuncture remains unclear due to the incompleteness of reporting. Future well-designed randomized trials with transparent reporting are required.

Evaluation of Scintillation Camera Applications of 3D Printing Phantom (3D 프린팅 팬텀의 섬광카메라 적용 평가)

  • Park, Hoon-Hee;Lee, Ju-young;Kim, Ji-Hyeon
    • Journal of radiological science and technology
    • /
    • v.44 no.4
    • /
    • pp.343-350
    • /
    • 2021
  • 3D printing technology is an additive manufacturing technology produced through 3D scanning or modeling method. This technology can be produced in a short time without mold, which has recently been applied in earnest in various fields. In the medical field, 3D printing technology is used in various fields of radiology and radiation therapy, but related research is insufficient in the field of nuclear medicine. In this study, we compare the characteristics of traditional nuclear medicine phantom with 3D printing technology and evaluate its applicability in clinical trials. We manufactured the same size phantom of poly methyl meta acrylate(PMMA) and acrylonitrile butadiene styrene(ABS) based on the aluminum step wedge. We used BrightView XCT(Philips Health Care, Cleveland, USA) SPECT/CT. We acquired 60 min list mode for Aluminum, PMMA and ABS phantoms using Rectangular Flood Phantom (Biodex, New York, USA) 99mTcO4 3 mCi(111 MBq), 6 mCi (222MBq) and 57Co Flood phantom(adq, New Hampshire, USA). For the analysis of acquired images, the region of interest(ROI) were drawn and evaluated step by step for each phantom. Depending on the type of radioisotope and radiation dose, the counts of the ABS phantom was similar to that of the PMMA phantom. And as the step thickness increased, the counts decreased linearly. When comparing the linear attenuation coefficient of Aluminum, PMMA and ABS phantom, the linear attenuation coefficient of the aluminium phantom was higher than that of the others, and the PMMA and ABS phantom had similar the linear attenuation coefficient. Based on ABS phantom manufactured by 3D printing technology, as the thickness of the PMMA phantom increased, the counts and linear attenuation coefficient decreased linearly. It has been confirmed that ABS phantom is applicable in the clinical field of nuclear medicine. If the calibration factor is applied through further research, it is believed that practical application will be possible.

The Effect of Electro Acupuncture for Sciatica: A Systematic Review and Meta-analysis (좌골신경통에 대한 전침 치료: 체계적 문헌고찰 및 메타분석)

  • Kim, Ye-Eun;Ahn, Jeong-Hoon;Cha, Yun-Yeop;Han, In-Sik;Heo, In;Park, In-Hwa
    • Journal of Korean Medicine Rehabilitation
    • /
    • v.32 no.2
    • /
    • pp.105-121
    • /
    • 2022
  • Objectives This study was conducted to evaluate the effect of electro-acupuncture for sciatica. Methods We searched 13 online databases (Kmbase, Research Information Sharing Service [RISS], National Digital Science Library [NDSL], Oriental Medicine Advanced Searching Integrated System [OASIS], Koreanstudies, Koreantk, DBpia, PubMed, Cochrane, EMBASE, Medline, China National Knowledge Infrastructure [CNKI], J-stage) to find randomized-controlled clinical trials (RCTs) that used electro-acupuncture for sciatica. Efficacy rate and visual analogue scale (VAS) were mainly analyzed as a main evaluation criteria. Results Among 583 articles that were searched, 24 RCTs were finally selected and 18 RCTs were statistically analyzed. Electro-acupuncture was more effective than acupuncture in terms of efficacy rate (p<0.00001) and VAS (p<0.00001). Also, Electro-acupuncture was more effective than western medication in terms of efficacy rate (p=0.0005). However, the effectiveness of electro-acupuncture was not identified compared to physical therapy (p=0.42). Electro-acupuncture significantly improved efficacy rate when combined with physical therapy than physical therapy alone (p<0.0001). In addition, electro-acupuncture plus Chuna manual therapy compared to Chuna manual therapy alone showed positive results for efficacy rate (p=0.05) and VAS (p<0.0001). Conclusions Based on results, the effectiveness of electro-acupuncture for sciatica was identified. However, this study has limitations because the RCTs included in this study were small in number and published in a particular region. Although this study could be a groundwork for well designed research for sciatica.

A Comparative Study on User Perception by Metaverse Worldview Using SPICE (SPICE를 활용한 메타버스 세계관 별 사용자 인식 비교 연구)

  • Kim, Ahyun;Kim, Yong Jin;Kim, Sang Soo
    • Knowledge Management Research
    • /
    • v.23 no.2
    • /
    • pp.61-82
    • /
    • 2022
  • Metaverse is a combination of Meta and Universe, which refers to a world in which users or avatars engage in social, economic, and cultural activities. This study attempted to compare the four worldviews proposed by the Acceleration Studies Foundation (ASF) based on the five evaluation factors of SPICE, which are factors for promoting customer experience. 227 samples were used in the analysis, and as a result, seamlessness was the highest in augmented reality, interoperability in lifelogging, presence in the mirror world, and concurrence in virtual reality. This study is meaningful in that it presents a model design plan according to the classification of the metaverse platform and the worldview, and presents detailed strategic directions to existing metaverse platform operators or new entrants.