• Title/Summary/Keyword: Mental Illness

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Methylation Changes in Bipolar Disorder that can be detected through The Epigenetic Clock (후성유전학 시계를 통해 감지될 수 있는 양극성 장애의 메틸화 변화)

  • Yeon-Oh Jeong;Gwang-Won Cho
    • Journal of Integrative Natural Science
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    • v.16 no.3
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    • pp.75-80
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    • 2023
  • Bipolar disorder is a mental illness characterized by extreme mood and behavioral swings, such as highs of euphoria and lows of depression. It is a socially significant disorder in which people with the disorder experience intense mood swings and, for those with severe bipolar disorder, it is even difficult leading a normal life. High stress levels in people with mental illness can lead to neuroendocrine disruption, and it is strongly linked to aging. When the neuroendocrine system becomes vulnerable to these mental illnesses and stress, it is likely to accelerate aging. And it's the epigenetic clock that can measure the extent of this accelerated aging. The Epi clock, a pan tissue clock, measures aging through DNA methylation, and the degree of methylation is modified and changed by environmental conditions in the body. Therefore we wanted to check the changes in the epigenetic age of the patients with bipolar disorder. While we found no significant differences in epigenetic age, we did confirm the possibility that people with bipolar disorder have different methylation than normal people. We also found that the EPIC array data fit better on the Epi clock than on the Horvath clock with age-accelerated data from normal people.

외상후 스트레스 장애와 치과치료

  • Jeong, Yeong-Jeong;Baek, Gwang-U
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.9 no.1
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    • pp.1-8
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    • 2009
  • Posttraumatic stress disorder(PTSD) is a psychiatric illness that results from exposure to serious threats of injury or death. In addition, dental phobia, which is suggested as a sub-threshold form of PTSD, may result from aversive or painful dental treatment. Patients with PTSD may present greater dental and behavioral challenges than other patients due to their mental illness, neglect of oral hygiene, and their medication. Dentists have to consider the challenges to provide these patients with proper dental treatment.

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Causality between Spouse Attitude and Relapse of the Psychiatrically Disordered (정신장애인의 배우자 태도와 재발의 인과적 관계에 관한 탐색)

  • Shin, Sun-In
    • Korean Journal of Social Welfare
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    • v.60 no.3
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    • pp.59-82
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    • 2008
  • This study investigated the effect of spouse attitude of psychiatric patients on relapse. The research was based on the concept that spouses' attitudes toward mental illness influences relapse, mediated by marital relationship and social adaptation. Data were collected from 102 of the psychiatrically disordered who were married, and analyzed through Structural Equation Modelling to validate causal paths and mediator effects of the variables. The marital relationship was shown to act as a mediator between spouse attitude and social adaptation, while social adaptation showed a complete mediation effect between marital relationship and relapse. Thus, spouse attitude towards mental illness was shown to have a statistically meaningful effect on relapse indirectly and through sequential mediation effect of marital relationship and social adaptation. This study proposes the facilitation of counseling and training programs to improve the marital relationships of psychiatric patients. The emphasis is on the educational program for the spouses to improve their knowledge of mental illness.

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Latent Means Analysis of Perceived Stigma, Psychological Empowerment, Job Satisfaction According to the Working Hours among the Employed People with Mental Illness (취업 정신장애인의 근로시간 형태별 지각된 낙인감, 심리적 역량강화, 직무만족에 대한 잠재평균분석)

  • Lee, Yu-Ri
    • Journal of Digital Convergence
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    • v.16 no.1
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    • pp.431-438
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    • 2018
  • This study aimed to investigate the differences of perceived stigma, psychological empowerment, job satisfaction according to the working hours by latent means analysis(LMA). To get the results, a survey was conducted, targeting employed people with mental illness. Key outcomes of the analysis were as follows. First, it was verified that perceived stigma and job satisfaction, psychological empowerment had statistically meaningful direct relationships. Second, it was analyzed that psychological empowerment had a partial mediating effect in the relationship between perceived stigma and job satisfaction. Third, according to LMA, full-time group showed higher latent mean values on the perceived stigma and lower latent mean values on the job satisfaction. However, part-time group showed lower latent mean values on the psychological empowerment. Based in these results, comprehensive interventions for activating job satisfaction were proposed.

Factors Influencing Health Risk Behaviors of the Chronic Mental Illness in the Community (지역사회 만성정신질환자의 건강위험행위 영향요인)

  • Gang, Moonhee
    • Journal of Digital Convergence
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    • v.11 no.1
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    • pp.381-388
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    • 2013
  • The study was done to identify factors influencing the health risk behavior of the chronic mental illness in the community. A cross-sectional study design was used in this study. The sample was 255 chronic mentally ill persons from D city and C province and who agreed to participate in the study. Data were collected on August-september, 2011 and analyzed using the SPSS/WIN 20. Stress event, insight and depression had significant correlations with health risk behavior. Hierarchial regression analysis showed gender (men), diagnosis (schizophrenia), stress event, insight and depression together explained 24% of variance in health risk behavior. Findings of this study allow a comprehensive understanding of health risk behavior of the chronic mentally ill persons in community. It is necessary to integrated health promotion programs designed for this population should focus on these factors for effective behavioral modification.

Factors affecting the rehabilitation center exit and reentry among homeless persons with mental illness. (정신장애노숙인의 재활시설 퇴소 및 재입소 영향요인에 관한 연구)

  • Min, So-Young;Lee, Byung-Suk
    • Korean Journal of Social Welfare Studies
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    • v.42 no.1
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    • pp.219-242
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    • 2011
  • This study examined the factors associated with exit from and reentry into the rehabilitation center among homeless persons with mental illness. Shelter use of a total of 203 study population was monitored between 2004 and 2008. Cox's proportional hazard model was employed to analyze the factors influencing the rate of the first exit from and the first reentry into the rehabilitation center. Also, competing risk analysis was conducted to examine the factors differently associated with the type of the first exit from the rehabilitation center: a positive exit and a negative exit. This study found that homeless persons with mental illness were less likely to experience the negative exit while their resident registration status not being abolished on the first entry into the rehabilitation center, having more frequent hospitalizations during the rehabilitation center stay, being connected to the family members, having more participations into the basic rehabilitation, mental rehabilitation, and vocational rehabilitation programs during the rehabilitation center stay. Age, the number of hospitalization and of the participations into the mental rehabilitation programs during the rehabilitation center stay were associated with the rate of the first reentry into the rehabilitation center.

Symptoms of Posttraumatic Stress Disorder and Mental Health in Female Victims by Sex Trade : A Follow-Up Study in Shelter Samples (성매매 피해 여성의 외상 후 스트레스 증상과 정신건강-탈 성매매 후 추적 연구)

  • Kim, Seong-Cheol;Lee, Jun-Woo;Song, Jeong-Min;Jun, Tae-Youn;Chae, Jeong-Ho
    • Anxiety and mood
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    • v.2 no.1
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    • pp.33-38
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    • 2006
  • Objectives : Since prostitution is multitraumatic phenomena, it is known that most women in prostitution have symptoms of posttraumatic stress disorder (PTSD) and other mental illness. In Korea, new anti-prostitution law launched in the year of 2004 imposes protecting prostituted victims at government-supported shelter. The objective of this study was to compare the mental symptoms, especially PTSD features of women who escaped from prostitution with those of control subjects. Methods : We assessed 113 ex-prostituted women who live in shelter for 8 months on the average and 65 normal control subjects. Demographic data, questionnaire for sleep, physical illness, smoking, alcohol and drug use, Stress Response Inventory, Davidson Trauma Scale (DTS), Impact of Event Scale-Revised (IES-R) were used. Results : Ex-prostituted women had significantly higher scores of DTS, IES-R, stress related responses, sleep problems, smoking problems, and alcohol problems than control group. Age and duration of sex trade of the subjects were significantly correlated with the severity or frequency of PTSD symptoms. The degree of smoking, alcohol drinking and sleep problems were also significantly correlated with the PTSD symptoms. Conclusion : These results suggested mental symptoms did not disappear even after women escaped from prostitution.

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An Exploratory Analyses on Factors related to Mental Health Confidence among Individuals in Long-term Care Facilities: Focusing on the Differences by the Length of Hospitalization (정신요양시설 입소 정신장애인의 정신건강자신감 관련요인에 대한 탐색적 연구: 입소기간에 따른 차이를 중심으로)

  • Jeon, Hae Sook
    • The Journal of the Korea Contents Association
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    • v.16 no.3
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    • pp.563-574
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    • 2016
  • This study aimed to examine the predictors of mental health confidence(MHC) among individuals in psychiatric long-term care facilities(PLCF). It further examined whether the predictors and underlying mechanisms differed by the length of hospitalization. Sample consisted of 1,742 individuals residing in PLCF who participated in the Survey on PLCF. Structural equational modeling was used to examine the predictors of MHC. Multi-group Structural Equation Modeling(SEM) was used to examine whether the predictors and mechanisms differed by the length of hospitalization between those of 10 years or less (n=962) and 10 years and more (n=780). Major findings were as follows. (1) Education, duration of mental illness, and psychiatric symptoms were significantly related to MHC. (2) Duration of mental illness presented significant indirect effects on MHC via its effects on perceived stigma. (3) The predictors and underlying mechanisms differed by the length of hospitalization. Based on the findings, implications and limitations of the research were discussed.

A Study on the Strategic Plans for Vocational Rehabilitation Services in Mental Rehabilitation Facilities: Based on the Focus Group Interview(FGI) of Vocational Rehabilitation Practitioners (정신장애인 정신재활시설의 직업재활서비스 활성화 방안 연구 -직업재활실무자의 초점집단인터뷰를 중심으로-)

  • Choi, Hee-Chul;Bae, Eun-Mi;Shin, Sook-Kyung;Park, Dong-Jin
    • Journal of Digital Convergence
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    • v.18 no.10
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    • pp.479-490
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    • 2020
  • The purpose of this study was to examine the perceptions of vocational rehabilitation practitioners in mental rehabilitation facilities related to their services, then it was intended to suggest the strategic plans for the services. To this purpose, data related to vocational rehabilitation services provided by mental rehabilitation facilities were collected, and a focus group interview(FGI) was conducted for the practitioners in charge of vocational rehabilitation services. And this data was analyzed to results. The research results are as follows. First, the related manuals and guidelines should be created to clarity the role and function of the facilities, that is the detailed standards are necessary for the workers participating in vocational rehabilitation services. Second, they expect that people with mental illness must be treated equally with other people with disabilities and the vocational rehabilitation services should be supported according to their disability characteristics. Based on the results of these studies, specific strategic plans for vocational rehabilitation services were suggested.

Traditional Chinese Medicine in the Treatment of Mental Retardation;A Review Study (정신지체에 대한 한의학 치료와 연구 동향;2003-2007년 중국 임상 논문에서)

  • Im, Jeong-Gyun;Kim, Lak-Hyung
    • The Journal of Pediatrics of Korean Medicine
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    • v.22 no.1
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    • pp.13-24
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    • 2008
  • Objectives This study was designed to analyze the clinical studies on Mental retardation(MR) in traditional Chinese medicine(TCM). Methods For this study, we searched the clinical studies on MR, which had been published from 2003 to 2007, through web site CNKI(中國知識基礎設施工 http://www.cnki.net). There were 17 clinical studies and we focused on those studies. Results 1. In those Chinese studies, they used following words to describe Mental retardation; 小人弱智($xi\check{a}o\acute{e}rru\grave{o}zh\grave{i}$), 智能發育不全($zh\grave{i}n\acute{e}ngf\bar{a}y\grave{u}buqu\acute{a}n$), 智力低下($zh\grave{i}l\grave{i}d\bar{i}xi\grave{a}$), 精神發育遲滯($j\bar{i}ngsh\acute{e}f\bar{a}y\grave{u}ch\acute{i}zh\grave{i}$), 智能落后($zh\grave{i}n\acute{e}nglu\grave{o}h\grave{o}u$), 智能落后($zh\grave{i}n\acute{e}ngch\acute{i}hu\check{a}n$), 失天愚型患人($xi\bar{a}nti\bar{a}ny\acute{u}x\acute{i}nghu\grave{a}n'\acute{e}r$). 2. There were many kinds of TCM treatment methods for MR, such as herbal medicine, acupuncture, electroacupunture, acupoint injection, Chuna therapy, and special education. And those TCM treatments methods showed higher efficacies in the treatment of MR compared with Western medicine. 3. Mental retardation was related with the deficiency of heart, kidney, liver, spleen(心虛, 腎虛, 肝虛, 脾虛) and the pathological mechanism of Phlegm(絹) and Blood stasis(慫沂)in the studies about the Bian Zheng-the types of differential diagnosis- of MR. 4. Most of studies used Intelligence Quotient(IQ) to assess the efficacy of TCM treatment of MR. And the duration of treatment, the degree of illness, the age of patient, and the cause of illness affected the prognosis of MR. Conclusions These results suggest that traditional medicine could be one of the useful treatments on MR. And these results could be used in the clinical practices and studies on MR in Korea.

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