• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1351-1355
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• 2014

Background: Ovarian sex-cord stromal tumours (SCST) are rare, and relatively infrequent in children. These have to be distinguished from more common germ cell tumors in children and also from benign epithelial neoplasms. Objectives: The purpose of our study was to report the clinical and pathological findings in young patients with these tumours in our population. Material and Methods: The present observational cross-sectional study included all subjects <21 years of age diagnosed with ovarian SCST, in Aga Khan University Hospital Histopathology Laboratory, Karachi, Pakistan, from January 1992 till July 2013. Results: Of the total of 513 SCSTs presented during the study period, 39 fulfilled inclusion criteria and were assessed. The age range was 4-250 months. Most of the tumours presented at stage-1 and an abdominal mass was the most common presenting symptom, along with menstrual disturbance. The left side ovary was slightly more affected (53.5%). Of the total, 15 were juvenile granulosa cell tumours (JGCT), 11 sclerosing stromal tumours (SST), 10 of the fibrothecomas spectrum, 2 Sertoli leydig cell tumours (SLCT) and one a sex cord tumour with annular tubules (SCTAT). Detailed immunohistochemical analyses were performed in 33 cases. Recurrence/metastasis was noted in 4/21 cases with follow-up data. Conclusions: Ovarian sex cord stromal tumours are very rare in young age in our population, and usually present at an early stage. Most common among these are juvenile granulosa cell tumours, although surprisingly sclerosing stromal tumours were also common. Clinical symptoms due to hormone secretion in premenstrual girls and menstrual disturbance in menstruating girls are common presenting features.

• CELLMED
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• v.6 no.1
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• pp.6.1-6.6
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• 2016

Polycystic Ovarian Syndrome (PCOS) has now become more common in occurrence in women of reproductive age, particularly in urban and semi-urban population in India. So there is a need to investigate this phenomenon taking into consideration various aspects including possible treatment method to ameliorate/eradicate this syndrome, which has far reaching socio-economic impact and consequences, in view of infertility and irregular menstrual cycles frequently associated with this syndrome. Homeopathy is a branch of traditional alternative medicine which is gaining popularity in India and some other developing countries, as also in some of the developed countries in Europe. With this background scenario, we have made an attempt to treat cases of confirmed PCOS and tried to compare the relative efficacy of two potentized homeopathic drugs, namely, Lycopodium clavatum (Lyco) and Calcarea carbonica (Calc), most frequently used by homeopathic practitioners, selecting different potencies of the drugs, depending on condition/guiding symptom(s) of the patients. While the main focus was pointed on total/partial removal of cysts, data pertaining to different PCOS associated symptoms were also compared for the sake of learning if the two drugs had differential effects on these symptoms also. The study parameters in this investigation included: regularity/irregularity of menstrual cycle, presence/absence of acne, hirsutism, male type alopecia, acanthosis nigricans, body/mass index (BMI) and waist-hip ratio. Overall results provided clear evidences that both these homeopathic drugs had great ameliorating effects on PCOS, although each drug had a little different effect in respect of the individual parameters of this study.

• The Journal of Korean Medicine
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• v.17 no.2 s.32
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• pp.405-417
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• 1996

An amenorrhoea means the pathologic condition that menstruation stops before the post menopausal period. Clinically, this is classified to both primary amenorrhoea and secondary amenorrhoea. Primary amenorrhoea indicate what has no first menstruation until 14 without secondary sexual sign or what has no first menstruation until 16 with secondary sexual sign before the time. Secondary amenorrhoea is diagnosised when a women with normal menstrual cycle before the onset doesn't have a menstruation over 6 months or appeals amenorrhoea for three times of her normal menstrual cycle. This clinical study was done on the patients who had come to gynecology department of oriental Hospital of Kyung Hee Medical Center from August 1, 1994 to July 31, 1995, complaining of amenorrhoea. The results obtained were as follows: 1. The amenorrhoea patient rate among outpatients who came to the deptment of gynecology was 3.4%. 2. The ratio between primary amenorrhoea and secondary amenorrhoea was 1 : 6.5. 33. The patient rate via other hospitals was 75% and Unremarkable finding(47.6%) was most numerous according to other hospital's diagnosis and hyperprolactinemia(11.9%), premature menopause(11.9%) were the second numerous diagnosis. 4. Unremarkable history(56.7%) was most numerous and among history, the fast(weight loss; 30%) was most numerous. 5. The most general symptom of amenorrhoea patient was indigestion(51.7%). 6. The most frequently used prescribtion for non-insurance was Onpojongoktang(溫胞種玉湯 ; 55%), for insurance was Gamisoyosan(加味逍遙散 ; 16.7%). 7. 25% patient show menstruation in their therapy and among this, 80% patient show menstruation within 40 days. 8. 26.9% secondary amenorrhoea patient show menstruation in their therapy and only one primary amenorrhoea patent(12.5%) shows the same result. 9. Among the effective used prescribtion, Onpojongoktang(溫胞種玉湯 ; 46.7%) is most numerous.

• Journal of Acupuncture Research
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• v.25 no.6
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• pp.55-66
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• 2008

Objectives : The aim of this study was to evaluate the effect of $SP_6$ moxibustion on the primary dysmenorrhea. Methods : The data was collected from subjects who was suffering for dysmenorrhea. The subjects were employed using Measure of Menstrual Pain(MMP) and Menstrual Symptom Severity List(MSSL) questionnaire. We treated the subjects with $SP_6$ moxibustion and measured Skin Resistance Variability(SRV) before and after treatment. The method of analysing data was paired t-test. Results : 1. $SP_6$ moxibustion produced a significant decrease in symptoms of primary dysmenorrhea. Results : 2. The SRV of 2, 3 area was significanltly changed after $SP_6$ moxibustion. Conclusions : $SP_6$ moxibustion was effective in decreasing the symptoms of primary dysmenorrhea. The SRV results suggest that women with primary dysmenorrhea may have organic energy deficiency and functional abnormality of the hypothalamus-hypophysis-ovarian axis.

• The Journal of the Korea Contents Association
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• v.14 no.9
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• pp.390-399
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• 2014

This research was conducted to determine the effects on knowledge about menstruation, coping with menstruation, menstrual symptom of middle school students after they received Health Behavior-based PMS Intervention Education. By using a non-equivalent control group pretest and posttest design, the experiment was conducted with a test group of 31 students and a control group of 33 students. There were statistically significant increases in knowledge about menstruation and coping with menstruation in the experimental group compared to the control group. From these finding, Health Behavior-based PMS Intervention Education for middle school students is effective and the development of such PMS Intervention Education is desirable in terms of health care.

• Journal of Acupuncture Research
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• v.24 no.3
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• pp.63-79
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• 2007

Objectives : Korean traditional acupuncture Theory, Sa-am's 5 phases acupuncture method was originated in 1644-1742, in the middle of the Cho Sun dynasty. This study was to verify the effect of Sa-am Acupuncture Treatment on dysmenorrhea of Women. Methods : The subjects were 49 volunteers who were suffering for dysmenorrhea, employed using Measure of Menstrual Pain (MMP) questionnaire. Subjects were divided into two groups including Sa-am acupuncture treatment group(n=23) and minimal acupuncture treatment group(n=26). They had agreed to take part in tIris experiment, with didn't take any anodyne drugs. In the acupuncture group, subjects were stimulated at $GB_{41}$, $SI_3$, $GL_{66}$, $SI_2$(Small intestine jung-guk) and $SP_6$. In the control group, subjects were needled at $L_{10}$, $S_{40}$, $P_5$, $G_{40}$ points have any effect on dysmenorrhea. A total of 5 acupuncture sessions were performed for each patient depending on the individual menstruation cycle. The MMP score by using 7 questions and the Menstrual Symptom Severity List(MSSL-D) were measured before and after menstruation cycle. Collected data were analyzed as frequency, percentage, paired t-test, independent t-test using SPSS 10.0 WIN Program. Results : Acupuncture treatment produced a significant improvement on dysmenorrhea in two groups, but a statistically significant difference was not shown in the acupuncture group compare to control group. Conclusions : Based on the above results, it was verified that Acupuncture Treatment was effective in decreasing the symptom of Dysmenorrhea.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.5
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• pp.3025-3036
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• 2014

This study was conducted to figure out the influential factors on premenstrual syndrome(PMS) of college female students which are to be utilized as the basic data to develop and apply programs for preventing and controlling such symptom. The subjects were 330 college female students. The data were collected from April 2, 2012 to April 6, 2012. From the results, There has been significant correlation between stress and PMS(r=.36, p<.001) and the attitude to menstruation has appeared to have significant positive correlation with PMS as well(r=.34, p<.001). Multiple regression analysis has been employed to identify the influential factors on PMS and the result has shown that menstrual attitude, grade point average for stress, smoking and dysmenorrhea have been the most significant influential factors with 27% of explanatory power. The level of significance has been high in menstrual attitude(${\beta}$=.28, p<.001), grade point average for stress(${\beta}$=.27, p<.001), smoking(${\beta}$=.20, p<.001) and dysmenorrhea(${\beta}$=.15, p<.001) respectively. In conclusion, it needs to find nursing interventions for PMS related to psychosocial factors and suggest a narrative study for improving quality of life of women with PMS.

• The Journal of Korean Society for School & Community Health Education
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• v.4
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• pp.97-115
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• 2003

Middle and high school girl students' menstruation characteristics, appearance of menstruation dysmenorrhea, and coping with the menstruation dysmenorrhea were examined in order to give information in instructing girl students about menstruation dysmenorrhea, in delivering health education in the school, and establishing health policy. 970 girl students in middle and high schools in Cheju-do were selected and surveyed using the questionnaire the author developed based on the previous studies. The findings are as follows. First, the age of first menstruation was average $12.9{\pm}1.22$ years. The younger they were, the earlier their first menstruation came. The most common menstrual cycle was such one that continuously irregular from the beginning or that regular and irregular cycle run together. The first irregular menstrual cycle changed regular one within 1 or 2 years. Most of the respondents had normal menstrual cycle of $21{\sim}35$ days and menstruation period of $3{\sim}8$ days. Second, symptom of menstruation dysmenorrhea was orderly; hurt in the underbelly, tired, hurt in the waist, and headache. It was higher with high school students than middle school students. For the most part, time of heavy menstruation dysmenorrhea was the 2nd day after menstruation starts and period of menstruation dysmenorrhea was 2 days. More than the half of the respondents felt that the present menstruation dysmenorrhea was similar with the first one and they felt not comport in daily life due to menstruation dysmenorrhea, and 'hard to live a normal life' was higher with the high school girl students than with the middle school students. Third, how to cope with menstruation dysmenorrhea was enough sleep, relax and rest, taking a hot water shower, listening to music or watching a movie, taking medicine, and doing excercise. Few of the respondents have ever visited a doctor due to menstruation dysmenorrhea, and the reason was mostly irregular menstruation and heavy dysmenorrhea. Forth, when they took medicine due to menstruation dysmenorrhea, they gathered information on the medicine from family members and friends, while extremely low from a pharmacist or a doctor. The most of them have ever took medicine during menstruation once and took standard dose. While excess dosage was higher with high school students than with middle school students. From these findings, a good many girls are experiencing menstruation dysmenorrhea since their first menstruation. To discover early the severely abnormal findings and to treat, more interest from home and school, counseling and sexual education on time, and expert's diagnosis are necessary. Rather than unconditionally taking pain-relievers which can plainly solve the pain, continuous health education at home and in the school should be carried on for the girls to practice proper measures one think effective or an expert recommends.

• Preventive Nutrition and Food Science
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• v.9 no.4
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• pp.383-388
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• 2004

This study was designed to identify how the incidence and severity of premenstrual. syndrome (PMS) correlate with the nutrient intakes and exercise habit of women. The subjects of this study were 299 women residing in Busan metropolitan city. Each subject was asked to complete a menstrual discomfort questionnaire (MDQ) for PMS and nutrient intakes. PMS symptom scores of women in their twenties ranked in order of severity were: behavioral change (2.45), followed by pain (2.36) and water retention (2.28), negative effects (2.20), autonomic reaction (1.91), arousal (1.87), decreased concentration (1.76) and decreased control (1.74). For Women in their thirties, the symptom of pain was the most dominant (2.93) followed by autonomic reaction (2.69) and behavioral change (2.54), and for those in their forties, negative effect (3.06) was highest, followed by pain (2.97) and autonomic reaction (2.86). The overall symptoms of PMS significantly increased with age (20': 2.07 points, 30': 2.34 points, 40': 2.47 points). There was no correlation of the BMI of the subjects with the symptoms of PMS, but there was a significant negative correlation between the symptoms of PMS and exercise frequency for women in their thirties and forties. Subjects in their twenties exhibited a significant negative correlation for PMS symptoms with the intake of carbohydrate (p < 0.05), calcium (p < 0.05) and vitamin E (p < 0.05). For subjects in their thirties, PMS symptoms were negatively correlated with the intake of calcium (p < 0.05) and vitamin C (p < 0.05); and in women in their forties, calcium (p < 0.01) and carbohydrate (p < 0.05) intakes were negatively correlated with PMS symptoms. This suggests that PMS represents the clinical manifestation of a nutrient deficiency state, especially calcium. Therefore, we concluded that nutrient supplementation and exercise management are likely to be of benefit in relieving PMS symptoms.

• Journal of Korean Academy of Nursing
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• v.32 no.3
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• pp.317-326
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• 2002

The purpose of this study was to verify the effect of aromatherapy on the stress response in menstrual period. Method: A randomized, single-blind, pretest- posttest design was used. The study subjects were 60 college women with dysmenorrhea and they were randomized into 3 groups, experimental, 1st control(placebo) and 2nd control group. The researchers massaged treatment oil(3% dilution essential oil of Lavender, Clary sage and Rose) into the abdomen of experimental group. The placebo group used almond oil(carrier oil) instead, and the 2nd control group did not give any treatment. Baseline data including pre-treatment stress response score were obtained on the first day of usual period. Aromatherapy provided for about 7 days until the next cycle began. Post-treatment stress responses were measured by 94 item SOS(symptom of stress) scale on the first day of the cycle. Results: As a results, the stress response score of experimental group was significantly lower than two control groups. And there was no significant difference in stress responses of two control groups. Conclusion: The results show aromatherapy using selected essential oils to be an effective intervention for stress response during menstruation.