• Title/Summary/Keyword: Memory function

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Electrospinning of Polyurethane Block Copolymers with Shape Memory Effect (형상기억효과를 가지는 전기방사된 폴리우레탄 부직포에 관한 연구)

  • Cha, Dong-Il;Kim, Hak-Yong;Jung, Yong-Chae;Cho, Jae-Whan;Chun, Byoung-Chul;Jung, Yong-Chan
    • Proceedings of the Korean Fiber Society Conference
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    • 2003.10b
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    • pp.261-262
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    • 2003
  • Shape memory polyurethane (PU) with soft and hard segments has been extensively researched since its discovery by Mitsubishi in 1988 [1]. Hard segments can be formed via hydrogen bonding and crystallization, function as physical crosslinks below melting point (Tm). The reversible phase transformation of the soft segment is responsible for the shape memory effect. (omitted)

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The Construction and Viterbi Decoding of New (2k, k, l) Convolutional Codes

  • Peng, Wanquan;Zhang, Chengchang
    • Journal of Information Processing Systems
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    • v.10 no.1
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    • pp.69-80
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    • 2014
  • The free distance of (n, k, l) convolutional codes has some connection with the memory length, which depends on not only l but also on k. To efficiently obtain a large memory length, we have constructed a new class of (2k, k, l) convolutional codes by (2k, k) block codes and (2, 1, l) convolutional codes, and its encoder and generation function are also given in this paper. With the help of some matrix modules, we designed a single structure Viterbi decoder with a parallel capability, obtained a unified and efficient decoding model for (2k, k, l) convolutional codes, and then give a description of the decoding process in detail. By observing the survivor path memory in a matrix viewer, and testing the role of the max module, we implemented a simulation with (2k, k, l) convolutional codes. The results show that many of them are better than conventional (2, 1, l) convolutional codes.

Charge retention characteristics of silicon nanocrystals embedded in $SiN_x$ layer for non-volatile memory devices (비휘발성 메모리를 위한 실리콘 나노 결정립을 가지는 실리콘 질화막의 전하 유지 특성)

  • Koo, Hyun-Mo;Huh, Chul;Sung, Gun-Yong;Cho, Won-Ju
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.06a
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    • pp.101-101
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    • 2007
  • We fabricated floating gate non-volatile memory devices with Si nanocrystals embedded in $SiN_x$ layer to achieve higher trap density. The average size of Si nanocrystals embedded in $SiN_x$ layer was ranging from 3 nm to 5 nm. The MOS capacitor and MOSFET devices with Si nanocrystals embedded in $SiN_x$ layer were analyzed the charging effects as a function of Si nanocrystals size.

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Belamcandae Rhizoma Extract Improves Memory Impairment in Mice (생쥐에서 사간 추출물의 기억력 감퇴에 대한 개선 효과)

  • Jung, Ji Wook
    • Korean Journal of Pharmacognosy
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    • v.52 no.1
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    • pp.55-60
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    • 2021
  • Belamcandae Rhizoma (BR), the rhizome of Belamcanda chinensis (L.) DC., possesses various biological properties such as anti-inflammatory activity, antioxidant activity and antimutagenic activity. However, there have been no studies on the anti-amnesic effect of BR. In this study, we assessed the improvement effect of BR extract on scopolamine-induced amnesia in mice. ICR mice were administrated with BR (50, 100 or 200 mg/kg, p.o.) and were subsequently injected of scopolamine (1 mg/kg, i.p.) 30 min before behavioral tasks (Y-maze, passive avoidance and Morris water maze tasks). To further assess the possible mechanisms of BR, the ex vivo acetylcholinesterase (AChE) activity was also evaluated. BR could ameliorate scopolamine-induced memory impairment and could regulate the cholinergic function by inhibiting the AChE activity. These data demonstrated that BR exert candidate extract against amnesia by restoring the cholinergic activity.

The Function of Memory CD8+ T Cells in Immunotherapy for Human Diseases

  • Hanbyeul Choi;Yeaji Kim;Yong Woo Jung
    • IMMUNE NETWORK
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    • v.23 no.1
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    • pp.10.1-10.16
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    • 2023
  • Memory T (Tm) cells protect against Ags that they have previously contacted with a fast and robust response. Therefore, developing long-lived Tm cells is a prime goal for many vaccines and therapies to treat human diseases. The remarkable characteristics of Tm cells have led scientists and clinicians to devise methods to make Tm cells more useful. Recently, Tm cells have been highlighted for their role in coronavirus disease 2019 vaccines during the ongoing global pandemic. The importance of Tm cells in cancer has been emerging. However, the precise characteristics and functions of Tm cells in these diseases are not completely understood. In this review, we summarize the known characteristics of Tm cells and their implications in the development of vaccines and immunotherapies for human diseases. In addition, we propose to exploit the beneficial characteristics of Tm cells to develop strategies for effective vaccines and overcome the obstacles of immunotherapy.

Prevalence and Characteristics of Chemotherapy-related Cognitive Impairment in Patients with Breast Cancer (유방암 환자에서 화학요법관련 인지기능저하의 발생률과 발생양상)

  • Park, Jin-Hee;Bae, Sun Hyoung;Jung, Yong-Sik;Jung, Young-Mi
    • Journal of Korean Academy of Nursing
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    • v.45 no.1
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    • pp.118-128
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    • 2015
  • Purpose: Evidence suggests that some patients with breast cancer experience cognitive difficulties following chemotherapy. This longitudinal study was done to examine the prevalence of cognitive impairment and trajectory of cognitive function over time in women with breast cancer, who received adjuvant chemotherapy. Methods: Participants were 137 patients with breast cancer. They completed neuropsychological tests and the Functional Assessment of Cancer Therapy-Cognitive Function before adjuvant therapy (pretest), toward the end of adjuvant therapy (posttest), and 6 months after the completion of adjuvant therapy (follow-up test). Of the patients, 91 were treated with adjuvant chemotherapy and 46 patients who did not receive chemotherapy made up the comparison group. A reliable-change index and repeated-measure ANOVA were used for statistical analyses. Results: At the posttest point, over 30% of patients showed complex cognitive impairment and reported greater difficulty in subjective cognitive function. At the follow-up test point, 22.0% of patients exhibited complex cognitive impairment and 30.8% of patients complained of subjective cognitive impairment. Repeated-measure ANOVA showed significant decreases after receiving chemotherapy followed by small improvements 6 months after the completion of chemotherapy in cognitive domains of change for attention and concentration, memory, executive function, and subjective cognitive function. Conclusion: These results suggest that chemotherapy in patients with breast cancer may be associated with objective and subjective cognitive impairments. Further studies are needed to explore the potential risk factors and predictor of chemotherapy-related cognitive changes. Also nursing interventions for prevention and intervention of cognitive impairments should be developed and tested.

The Effect of Multimodal Intervention through Virtual Reality-Based Immersion Program on Cognitive Function and Brain activity in Patients with Mild Cognitive Impairment (가상현실 기반 몰입형 복합중재프로그램이 경도인지장애 환자의 인지기능 및 두뇌 활성에 미치는 영향)

  • Ye-Rim Im;Sun-Min Lee
    • Journal of the Korean Society of Physical Medicine
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    • v.18 no.1
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    • pp.87-97
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    • 2023
  • PURPOSE: The purpose of this study was to investigate the effect of multimodal intervention through VR (virtual reality)-based immersion program on the cognitive function and brain activity of patients with mild cognitive impairment. METHODS: The subjects of the study were 10 people in the experimental group who applied a complex intervention that performed cognitive tasks using the movement of the upper extremities through the VR program, and 10 people in the control group who received traditional occupational therapy. After the study intervention was applied 5 times a week, 30 minutes a day for a total of 8 weeks, LOTCA-G(Lowenstein Occupational Therapy Cognitive Assessment for Geriatric Population) and NIRSIT LITE were used to compare. RESULTS: Significant differences in cognitive function and brain activity were noted between the pre- test and post-test in the experimental group. Brain activity showed statistically significant differences in four channels of the working memory domain and one channel of the metacognitive domain (p < . 05). Comparative analysis of the difference between the two groups revealed statistically significant differences in cognitive function and brain activity. The brain activity showed statistically significant differences in three channels of the working memory domain and one channel of the metacognitive domain (p < .05). CONCLUSION: Through the results of this study, it was found that the complex intervention of performing cognitive tasks using upper extremity movements through the VR program had a positive effect on the cognitive function of patients with mild cognitive.

Current Research Trends on Executive Function in Children (국내 아동 실행기능 연구의 최근 동향)

  • Lee, Jumi
    • Korean Journal of Child Studies
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    • v.38 no.2
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    • pp.17-35
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    • 2017
  • Objective: The purpose of this study was to explore research trends in childhood executive function in Korean academic journal articles. This study showed which population groups were studied, which factors of executive function were measured, and which domains were studied in the selected articels. Methods: A systematic review of empirical studies of childhood executive function published in Korean academic journals from 2006 to 2016 was conducted. Through searching the KERIS database, 60 empirical studies were selected for review. Results: The results of the analyses showed that the population group the most studied was normal young children and that factors of executive function most studied were inhibition, cognitive flexibility, and working memory. Conclusion: Based on this systematic review of empirical studies of childhood executive function, several suggestions for future research are addressed.

A Preliminary Study on Validity of Korean Behavior Rating Inventory of Executive Function-Preschool Version(BRIEF-P) (한국판 유아용 실행기능 척도(BRIEF-P)의 타당화를 위한 예비연구)

  • KOWN, Yeon-Hee
    • Journal of Fisheries and Marine Sciences Education
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    • v.29 no.2
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    • pp.436-446
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    • 2017
  • This study was performed to verify the validity and utility of the Korean Behavior Rating Inventory of Executive Function-Preschool Version(BRIEF-P). The BRIEF-P is one of the most used instruments to measure Executive Function(EF) and a teacher-rating assessment method designed to measure the executive function of preschoolers(age 2-5). A total of 200 preschoolers(104 boys, 96 girls; recruited aged 3 to 5years) participated. Confirmatory factor analysis was carried out to evaluate the model structure. Correlation analysis was done to verify the concurrent validity. In the results, the model fit indexes were good with the five BRIEF-P subscales (that is, inhibit, shift, emotional control, working memory, plan/organize). The internal consistency of the BRIEF-P five subscales were supported. As a results, the Korean Behavior Rating Inventory of Executive Function-Preschool Version(BRIEF-P) was confirmed to be a reliable and valid assessment tool to measure executive function in preschoolers.

창원시 대산면 강변여과수의 수질과 낙동강 수질의 관련성 연구

  • 장성;함세영;김형수;차용훈;정재열
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2004.04a
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    • pp.451-454
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    • 2004
  • The study aims to assess the quality of bank filtrate in relation to streamflow and physico-chemical properties of the stream. Turbidity, pH, temperature and dissolved oxygen (DO) of Nakdong River and riverbank filtrate were statistically analyzed. The physico-chemical properties of riverbank filtrate were measured from irregularly different seven pumping wells every day. Autocorrelation analyses were conducted to the qualities of stream water and bank filtrated water. Temperature, pH and DO of streamflow shows strong linearity and long memory effect, indicating the effect of seasonal air temperature and rainy season. Temperature of riverbank filtrate shows weak linearity and weak memory, indicating differently from the trend of stream temperature. Turbidity of steramflow shows strong linearity and long memory effect, while turbidity of riverbank filtrate indicates weak linearity and weak memory. Cross-correlation analysis shows low relation between turbidity, pH, temperature and DO of riverbank filtrate and those of streamflow. Turbidity of streamflow was largely affected by the streamflow rate, showing a similar trend with autocorrelation function of streamflow rate. The turbidity of riverbank filtrate has a lag time of 25 hours. This indicates that turbidity of streamflow in a dry season has very low effect on the turbidity of riverbank filtrate, and a high turbidity of the stream in a rainy season has a fairly low effect on the turbidity of riverbank filtrate.

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