• 대한한의학회지
• /
• 제43권2호
• /
• pp.61-74
• /
• 2022

Objectives: This study aimed to explore the short-term effects of bilateral masticatory training using an intraoral device on memory and concentration, which is an advanced form of Gochi, compared to the unilateral form with gum. Methods: Thirty young healthy participants (age, 16-30 years) were screened and randomly assigned to one of two sequences in a crossover design. The participants assigned to sequence A (n=15) performed bilateral mastication using an intraoral device with a total of 300 taps, followed by unilateral mastication using gum with the same number of repetitions and frequency, separated by a 7-day washout period. A reverse order was used for sequence B. The primary and secondary outcomes were the digit span test result and the symbol digit modality test and the word list recall results, respectively, which were conducted before and after each intervention. Results: Symbol digit modality test scores increased by 12.03±8.33 with bilateral mastication, which was significantly higher than that obtained with chewing gum (5.17 points;95% confidence interval: 0.99, 9.34; p<0.05). Changes in the digit span test and word list recall scores were not significantly different between the two groups. In the digit span test forward, symbol digit modality test, and word list recall test, bilateral mastication was not inferior to unilateral mastication in improving memory and concentration. Conclusions: Bilateral masticatory exercises using an intraoral device are not inferior to unilateral mastication with gum for improving memory in healthy young individuals. Further research is needed to determine the efficacy of bilateral masticatory training on cognitive function.

• 대한한방소아과학회지
• /
• 제23권3호
• /
• pp.241-262
• /
• 2009

Objectives This study is designed to investigate the effects of Jujadokseo-hwan on the brain ability and inducing oxidative stresses. Methods We measured the changes of regional cerebral blood flow and mean arterial blood pressure. Then we analyzed histological examination, immunohistochemistric response and anti-oxidant activity of Jujadokseo-hwan. Results 1. Treatment of Jujadokseo-hwan significantly increased regional cerebral blood flow but decreased mean arterial blood pressure. 2. Treatment of Jujadokseo-hwan-induced increase of regional cerebral blood flow was significantly inhibited by pretreatment with indomethacin (1 mg/kg, i.p.), an inhibitor of cyclooxygenase. 3. In histological examination through TTC stain, group I was no change, but group II showed that discolored in the most cortical part. Group III showed that decreased discolor in the cortical part. 4. In immunohistochemistric response of BDNF, group II showed that lower response effect. Group III showed that increase response effect. 5. Treatment of Jujadokseo-hwan increased proliferation rates of Glial cell effectively 6. Treatment of Jujadokseo-hwan accelerated proliferation rates of C6 cells in vitro. In addition, protective effects on cell death induced by paraquat, rotenone and hydrogen peroxide. In addition, activity of SOD were increased by treatment with Jujadokseo-hwan. Conclusions In conclusion, Jujadokseo-hwan can improve of the brain ability, learning ability, memory ability and induce ischemic brain injuries.

• 재활치료과학
• /
• 제9권3호
• /
• pp.77-89
• /
• 2020

목적 : 본 연구는 라파엘 스마트 페그보드를 사용한 시청각 바이오피드백 훈련이 뇌졸중 환자의 인지기능에 미치는 영향에 대해 알아보고자 한다. 연구방법 : 본 연구는 시청각 바이오피드백 훈련을 적용한 중재집단 10명, 자가 활동 프로그램을 적용한 대조집단 10명으로 구분하여 총 20명의 뇌졸중 환자를 대상으로 진행하였다. 중재 전·후의 인지기능 평가는 K-MoCA와 NCSE를 사용하였고, 중재집단의 중재 방법은 전통적 작업치료와 시청각 바이오피드백 훈련을 10주간, 주 3회, 30분씩, 총 30회기 제공하였으며, 대조집단에는 전통적 작업치료와 자가 활동 프로그램을 중재집단과 같은 기간 동안 제공하였다. 결과 : 첫째, 중재 전·후에 따른 집단 간 K-MoCA의 결과는 중재집단이 대조집단보다 시공간 및 집행기능, 주의력, 기억력, K-MoCA 전체 점수 항목에서 유의한 차이가 있는 것으로 나타났다(p<.05). 둘째, 중재 전·후에 따른 집단 간 NCSE의 결과는 중재집단이 대조집단보다 주의력, 기억력, NCSE 전체 점수 항목에서 유의한 차이가 있는 것으로 나타났다(p<.05). 결론 : 본 연구에서는 시청각 바이오피드백 훈련을 통해 뇌졸중 환자의 전반적인 인지기능에 긍정적인 효과가 있음을 확인하였고, 특히 시공간과 관련된 영역과 주의력 및 기억력 향상에 더욱 효과가 있음을 확인하여 해당 도구가 작업치료 임상 환경에서 뇌졸중 환자의 재활을 위한 도구로 유용하게 사용될 수 있을 것으로 생각한다. 따라서 추후 연구에서는 라파엘 스마트 페그보드를 사용한 시청각 바이오피드백 훈련의 다양한 임상적 연구가 진행되어야 할 것으로 생각한다.

• 한국해양공학회지
• /
• 제15권4호
• /
• pp.115-119
• /
• 2001

The simulation of motion responses of a dolphin-moored ocean structure in shallow water when it cllides with a ship, has been carried out. The equation of motion in the time domain according to Cummin's theory is employed, and solved by making use of the Newmark-${\beta}$ method. The added mass and damping coefficients involved in the equations are abtained from a three-dimensional panel method in the frequency domain. The impact forces due to ship collision are calculated using both the elastic and non-elastic modelings. The mooring forces for dolphin systems of ocean structure are regarded as linear spring forces.

• 대한산업공학회지
• /
• 제25권1호
• /
• pp.111-124
• /
• 1999

This evapaper is toluate the forecasting performance of three neural network(NN) approaches against ARIMA model using the famous time series analysis competition data. The first NN approach is to analyze the second Makridakis (M2) Competition Data using Multilayer Perceptron (MLP) that has been the most popular NN model in time series analysis. Since it is recently known that MLP suffers from bias/variance dilemma, two approaches are suggested in this study. The second approach adopts Cascade Correlation Network (CCN) that was suggested by Fahlman & Lebiere as an alternative to MLP. In the third approach, a time series is separated into two series using Noise Filtering Network (NFN) that utilizes autoassociative memory function of neural network. The forecasts in the decomposition analysis are the sum of two prediction values obtained from modeling each decomposed series, respectively. Among the three NN approaches, Decomposition Analysis shows the best forecasting performance on the M2 Competition Data, and is expected to be a promising tool in analyzing socio-economic time series data because it reduces the effect of noise or outliers that is an impediment to modeling the time series generating process.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 1991년도 추계학술대회 논문집
• /
• pp.1-4
• /
• 1991

EEPROM technology has been used for storing analog weights as charge in a nitride layer between gate and channel of a field effect transistor. In the view of integrity and fabrication process, it is essentially required that SONOSFET is capable of performing synapse function as a basic element in an artificial neural networks. This work has introduced the VLSI implementation for synapses including current study and also investigated physical characteristics to implement synapse circuit using SONOSFET memories. Simulation results are shown in this work. It is proposed that multiplication of synapse element using SONOSFET memories will be developed more compact implementation under Present fabrication processes.

• 한국해양공학회:학술대회논문집
• /
• 한국해양공학회 2000년도 추계학술대회 논문집
• /
• pp.57-62
• /
• 2000

The very large flcating structure which am be used for as airport may be as large as several kilomet wide. The first order wave forces as well as wave drift forces are very important forces on such a very large floating In the present studv, the time simulation of motion responses with dolphin-moored VLFS in waves is presented The coeffcients and wave forces involved in the equations are obtained from a three-dimensionul panel method in the frequc The horizontal drift forces and mooring forces for dolphin systems are taken into account. As for numerical example, analyses are carried out for a VLFS in irregular wave condition

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 1996년도 추계학술대회 논문집
• /
• pp.1-4
• /
• 1996

EEPROM technology has been used for storing analog weights as charge in a nitride layer between gate and channel of a field effect transistor. In the view of integrity and fabrication process, it is essentially required that SONOSFET is capable of performing synapse function as a basic element in an artificial neural networks. This work has introduced the VLSI implementation for synapses including current study and also investigated physical characteristics to implement synapse circuit using SONOSFET memories. Simulation results are shown in this work. It is proposed that multiplication of synapse element using SONOSFET memories will be developed more compact implementation under Present fabrication processes.

• 한국해양공학회:학술대회논문집
• /
• 한국해양공학회 2001년도 춘계학술대회 논문집
• /
• pp.222-227
• /
• 2001

The time simulation of slow drift motions of moored FPSO in waves is presented. The equation of motion based on Cummin's theory of impulse responses are employed, and are consisted of horizonal plane -surge, sway and yaw. The added mass coefficients, wave damping coefficients, first order wave exciting forces and the second order wave drift forces involved in the equations are obtained from a three-dimensional panel method in the frequency domain. The mooring lines are modeled quasistatically as catenary for chains and touchdown. As for numerical example, time domain analyses are carried out for a box-type FPSO in long crest irregular wave condition.

• 한국해양공학회:학술대회논문집
• /
• 한국해양공학회 2001년도 춘계학술대회 논문집
• /
• pp.103-107
• /
• 2001

When ship claps against the ocean structure sited at shallow water, the time simulation of motion responses of dolphin-moored ocean structure is presented. The equatien of motion based on Cummin's theory of impulse responses are employed, and solved in time domain by using the Newmark $\beta$ method. The added mass and damping coefficients involved in the equations are obtained from a three-dimensional panel method in the frequency domain. The impact forces due to ship collision are modeled as two method, and those are elastic and non-elastic collisions. The mooring forces for dolphin systems of scean structure are considered as linear spring system.