• Tuberculosis and Respiratory Diseases
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• 제70권3호
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• pp.257-260
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• 2011

A 65-year-old woman was admitted due to poor oral intake and a dry cough over the previous 3 months. The physical examination was remarkable for bibasilar crackles, and plain chest radiography showed reticulation in both lower lung fields. A pulmonary function test demonstrated a restrictive pattern with a reduced diffusing capacity of the lung for carbon monoxide. High resolution computed tomography showed reticulation and honey-combing in both peripheral lung zones, which was consistent with usual interstitial pneumonia pattern. Her skin showed livedo reticularis. The erythrocyte sedimentation rate and C-reactive protein level were elevated, and hematuria was noted on urinary analysis. A serologic test for auto-antibodies showed seropositivity for Myeloperoxidase-Anti-neutrophil cytoplasmic antibody (MPO-ANCA). A kidney biopsy was performed and showed focal segmental glomerulosclerosis. She was diagnosed as having pulmonary fibrosis with microscopic polyangiitis (MPA) and treated with high dose steroids. Here we report a case of pulmonary fibrosis coexistent with microscopic polyangiitis.

• Tuberculosis and Respiratory Diseases
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• 제67권6호
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• pp.560-564
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• 2009

Sarcoidosis is a granulomatous disease that can involve any organ, although it primarily involves the lungs, intrathoracic lymph nodes, skin, and eyes. We present a case of sarcoidosis with pancytopenia, resulting from bone marrow involvement. A 35-year-old man was admitted to hospital for chronic cough and blurred vision. On chest computed tomography, there were multiple pulmonary nodules and mediastinal lymph nodes enlargement. As the patient also showed pancytopenia, we performed a bone marrow biopsy, as well as a transbronchial lung biopsy. Both biopsies showed non-caseating granulomas. We diagnosed the patient with sarcoidosis with pulmonary, bone marrow, uvea, liver and spleen involvement. After oral steroid therapy, the patient's symptoms as well as his pancytopenia improved. We present this case to demonstrate the significance of bone marrow biopsy in cases of sarcoidosis with pancytopenia, as well the possibility of clinical improvement with steroid treatment.

• 한국의사학회지
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• 제31권2호
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• pp.63-72
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• 2018

As Korea's representative medical text, "Donguibogam" reveals Korean Medicine's unique perspective on the human body. The text also contains abundant resources related to skin, leading to diverse researches on the subject today. In this paper, authors tried to elicit values of "Donguibogam" in the general cosmetics field, through literature review. First, prescriptions related to main functions of modern cosmetics (anti-aging, whitening, and moisturizing) were classified. In relation to anti-aging, concepts such as 返老 (reversing aging), 還童 (to become young again), 皺 (wrinkle), and 皮急 (tense skin) were extracted and 69 examples of treatments were introduced. For whitening care, 41 treatments were mentioned on hyper-pigmentation and general complexion. Concepts related to moisturizing included expressions such as 潤肌膚 (hydration of skin) and 光澤 (glow), induced by 48 treatment prescriptions. Second, cosmetics related prescriptions were classified according to the application methods of modern cosmetics. 78 prescriptions of cleansing category included washing-off local area with herbal liquid, bathing, washing-off after steaming, and soaking the body in the herbal liquid. Total of 308 topical application prescriptions covered the conditions of various skin inflammations, scalp illnesses, and etc. In conclusion, this research examines the value of "Donguibogam" as a useful of skincare. Further studies are expected to extend our understanding of the field.

• KSBB Journal
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• 제25권2호
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• pp.116-122
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• 2010

Fermented materials have been used for long time around the world and have been researched according to the excellent effect in the part of medical and food industry. However, when such materials are applied on skin, because of the skin barrier, the most effective ingredients are poorly absorbed. The absorption of the skin is exceedingly limited and the method of increasing skin absorption needs special procedures. The micro-needle therapy is a method used to improve the absorption of drug (solution) in the skin which is called "natural skin rejuvenation therapy". This therapy uses micro-needle which is equipped with very thin, delicate needles smaller than a 0.07 mm thick hair. During this therapy, the micro-needle makes small holes and helps absorb the solution into the skin. This is a very excellent therapy in skin absorption. It can be used in wide regions of the skin without any side effects and no recovery time. In 2007, the micro-needle is permitted to personal care. However, the solutions have not yet been developed professionally, and such skill is needed.

• 한국응용과학기술학회지
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• 제36권1호
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• pp.113-124
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• 2019

The purpose of the study was to investigate the effects of sea cucumber extract on skin as a natural cosmetics functional material. Subjective evaluation of cosmetics before and after were conducted with questionnaires regarding moisture content, sebum content, melanin index, and erythema index. Experiments were conducted on improvement efficacy using skin clinical trials and questionnaires to evaluate changes in perception of skin condition and efficiency of products. With the aim of minimizing skin irritation, the efficiency of the solvent used for extraction was an important factor, and the sea cucumber extract was harvested with efficient extraction conditions at a ratio of 1:10 of 50% ethanol. The study aimed to identify the suitability of sea cucumber extract as a functional cosmetics material to improve the moisturizing ability of skin and its effect on the skin by adding marine natural animal sea cucumber extract. Clinical studies on cosmetics skin containing sea cucumber extract, excellent skin improvement effect from all items of clinical experiment in experimental and control groups. Sea cucumber extract was proved to be a stable, non-adverse physiologically active substance against abnormal symptoms or side effects of skin reactions and skin problems. In addition, the study found excellent results that can lead to its use as a cosmetics material. This is expected to contribute to the development of various cosmetics industries.

• Tuberculosis and Respiratory Diseases
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• 제59권4호
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• pp.406-412
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• 2005

연구배경 : 최근 말초혈액을 결핵균 특이 항원으로 자극후 분비되는 $IFN-{\gamma}$ 를 측정하는 $QuantiFERON^{(R)}-TB$ Gold (QFT) 와 T $SPOT-TB^{(R)}$(SPOT) 검사가 임상에서 잠복결핵의 진단에 상품화되어 사용되고 있다. 그러나 이전에 시행한 투베르쿨린 검사가 상기 체외 $IFN-{\gamma}$ 검사의 위양성을 유발할 수 있는 가능성에 대해서는 아직 발표된 자료가 없다. 방 법 : 과거 결핵치료력 또는 환자 접촉력이 없는 46명의 15세 남자 고등학생을 대상으로 하였다. 혈액을 채취하여 $IFN-{\gamma}$ 검사를 시행하고, 이단계 TST를 시행하였다. 첫 번째 검사에서 $IFN-{\gamma}$ 검사와 TST가 모두 음성인 학생을 대상으로 하여 2개월 째에 TST, 2개월, 4개월 째에 QFT, 그리고 2개월 째에 SPOT 검사가 반복 시행되었다. 결 과 : TST 경결 크기의 평균값은 $3.1{\pm}5.4mm$ (범위: 0-20)였고, 이단계 TST에서 최종 13/46명(28.3%)이 양성 결과를 나타내었다. SPOT검사는 9명(19.6%)에서 양성이었으며 QFT는 1명(2.2%)에서만 양성이었다. 첫 $IFN-{\gamma}$ 검사와 TST에서 모두 음성인 학생 24명에서 2개월에 시행한 TST 모두 음성이었다. 2개월(23명) 및 4개월(25명)에 시행한 QFT 검사는 모두 음성이었다. 2개월에 SPOT 검사를 시행한 23명 중 1명(4.3%)에서 약양성 결과를 보였다. 결 론 : 두 가지 체외 $IFN-{\gamma}$ 검사의 결과에 일부 차이가 있었으나 2개월 및 4개월 이전에 시행된 TST가 체외 $IFN-{\gamma}$ 검사결과에 영향을 미치지 않음을 알 수 있었다.

• 한방안이비인후피부과학회지
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• 제21권2호
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• pp.126-141
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• 2008

Objective : This clinical research was conducted to test patients with Atopic Dermatitis by external application with Yeongyuseungmatang in cosmetics. Methods : We gave scores to 33 patients who visited the Dept. of Oriental Medical Opthalmology & Otolaryngology & Dermatology of Semyung Jecheon Oriental Medical Hospital from April 17th, 2008 to June 12th. Seventeen patients were treated with Yeongyuseungmatang(Experimental group) and sixteen patients were treated with Atopico skin care cream(Control group) for 4weeks. We observed change of total IgE, eosinophil count, Skin Temperature, Transepidermal Water Loss(TEWL), Skin Hydration and Skin pH. Also Clinic Index of Atopic Dermatitis(SCORAD Index) and global assesment of efficacy were used to evaluate the effects of Yeongyuseungmatang. Statistical analysis was performed by using frequency analysis and descriptive analysis. Statistical significance was achieved if the probability was less than 5%(p<0.05). Results : 1. After 4 weeks of external application treatment, SCORAD Index in Yeongyuseungmatang was significant statistically decreased compared with control group. 2. After 4 weeks of external application treatment, eosinophil count in Yeongyuseungmatang was significant statistically decreased compared with control group but total IgE was very increased both Yeongyuseungmatang and control group. 3. Statistically, Yeongyuseungmatang and control group didn't showed significant effect on Skin Temperature was measured by Thermometer SM815. 4. Transepidermal Water Loss(TEWL) in Yeongyuseungmatang was significant statistically decreased compared with control group measured by Tewameter TM300. 5. Skin Hydration in Yeongyuseungmatang was significant statistically increased compared with control group measured by Corneometer CM825. 6. Statistically, Yeongyuseungmatang and control group didn't showed significant effect on Skin pH was measured by Skin-pH-Meter PH905. 7. After 4 weeks of external application treatment, Yeongyuseungmatang showed significant effect on global assesment of efficacy. Conclusion : Considering the above results, we can speculate that cosmetics with Yeongyuseungmatang has some therapeutical effects in mitigating the symptoms of atopic dermatitis.

• Journal of Preventive Medicine and Public Health
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• 제9권1호
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• pp.147-151
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• 1976

A study was conducted during the period of August 13 to August 18, 1974 to obtain information on knowledge and attitude of the rural area housewife toward health care and antibiotics using. Interviewed 242 housewives dwelling in Soodong and Hwado Myun, Yangju Gun, Kyunggi Do, a typical rural area in Korea and the following results are obtained: 1. Of 242 housewives interviewed, 20.2% were illiteracy, 68.2% was graduated from primary school, 9.1% from middle school and 2.5% from high school. 2. Of those interviewed, 8.7% were Christian, 5.0% Bueldist, 2.9% Confucianism, and 83.4% of those were no religious preference. 3. Utility rate according with the kind of mass media in home was 85.1% of respondants possessed radio, 16.1% of magazine, 12.8% of newspaper, and 4.1% of television. 4. In the case of patients occure in a family, 13.0% out of 242 respondants had chosen physician's clinics for inicial medical care place, 58.4% drug stores, 0.9% herb medicine and 27.7% of those had chosen folk medicine at home. 5. Antibiotics effective complaints listed by the respondants were skin diseases with 43.8%, suppurated wound 30.0%, URI like symptoms 18.2%, diarrhea 14.5%, low back pain 12.9%, fever 6.2%, loss of appetite 3.3%, all kind of diseases 2.5%, urethral discharge 2.1% and tuberculosis 0.8% respectively. 6. Only 14.7% of respondants had obtained antibiotics for medical care from physician's clinics and 85.3% of the respondants had obtained antibioties from drug store (70.7%), village shop (10.4%), and salesmen in street market without any physician's prescription. 7. Eighty-nine percent of the respondants were understanding on patient care activity as the local health subcenter but only 11.0% of those on M.C.H., 29.0% of those on family planning, 21% on vaccination, and only 6.6% on tuberculosis control activity. 8. Utility rate of the local health subcenter was 71.9% out of the patients indicated medical care of medical facilities.

• Tuberculosis and Respiratory Diseases
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• 제71권6호
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• pp.459-463
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• 2011

Pulmonary complications occur in 40~60% of patients who receive hematopoietic stem cell transplantation (HSCT) and are a source of substantial morbidity and mortality. Acute eosinophilic pneumonia (AEP) is an uncommon, non-infectious pulmonary complication occurring in HSCT recipients. We now report the case of a 52-year-old man with AEP who was treated with allogenic HSCT due to acute myeloid leukemia. He complained of fever, cough and dyspnea 390 days after allogenic HSCT. He also had skin and hepatic graft versus host disease (GVHD). Hypoxemia, diffuse pulmonary infiltrates on a chest x-ray and eosinophilia in bronchoalveolar lavage fluid were also noted in several tests. His symptoms, pulmonary infiltrates, hepatic dysfunction and skin lesions rapidly improved after treatment with corticosteroid therapy. Our case supports the idea that AEP is a late phase non-infectious pulmonary complication and one of the manifestations of chronic GVHD.

• Archives of Plastic Surgery
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• 제45권4호
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• pp.325-332
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• 2018

Background Zygomaticomaxillary complex (ZMC) fractures mostly occur in the form of tripod fractures. The surgical field is accessed using a combination of three classic approaches. However, the subciliary incision may have unfavorable aesthetic results. Herein, the authors report the advantages of the extended transconjunctival approach (ETA) combined with T-bar screw reduction in minimizing scarring and complications for the treatment of ZMC fractures. Methods A total of 26 patients underwent ZMC reduction through the ETA and intraoral approach. A skin incision measuring roughly 5 to 8 mm in length was placed following the lateral canthal skin crease. After releasing the inferior crus of the lateral canthal tendon for canthotomy, the medial periosteum of the lateral orbital rim was preserved for canthal reattachment. A limited subperiosteal dissection and partial relaxing incision of the orbicularis oculi were performed to expose the fracture line of the inferior orbital rim and zygomaticofrontal suture. Reduction was performed using a T-bar screw through the transconjunctival incision and an elevator through the intraoral incision. Results The aesthetic and functional results were excellent. Successful reduction was achieved and the skin incision was less than 8 mm in 20 cases (76.9%). Only six patients had an additional skin incision (less than 5 mm) to achieve reduction. No cases of ectropion, entropion, or excessive scarring were noted. Conclusions The ETA using a T-bar screw is a useful method for maximizing aesthetic results in ZMC fractures, with the advantages of minimal scarring, faster recovery, and maintenance of pretarsal fullness.