• 디지털융복합연구
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• 제11권9호
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• pp.289-299
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• 2013

본 연구의 목적은 현재 질병관리본부에서 사용하고 있는 건강보험 청구자료 기반의 결핵환자 분류기준을 고도화하여 보다 효과적인 결핵환자감시체계의 토대를 제공하기 위해 수행되었다. 이를 위해 건강보험심사평가원의 2009년 1년간 결핵상병으로 청구된 81,199명 중 10%인 8,118명을 표본추출한 후 실제 결핵환자인지에 대해서 의무기록 조사를 실시하여 조사가 완료되고, 국민건강보험공단 건강보험청구 자료와 매칭이 완료된 7,132명을 최종 분석대상자로 하였다. 결핵환자분류를 위한 모형을 개발하여 평가한 결과 결핵과 관련된 임상전문가 의견과 통계적 분류 알고리즘이 종합적으로 고려된 의사결정나무모형이 가장 우수한 모형으로 평가되었다. 의사결정나무 모형에 따른 결핵분류모형의 주요 독립변수는 연령, 최초 청구시점의 결핵약제 종류수, 최초 청구시점의 이용 의료기관 유형, 최초 청구시점의 청구결핵검사 종류, 2008년 결핵약 투약일수, 최초 청구시점 결핵약제 투약일수, 최초 청구시점 결핵상병 종류로 나타났다. 이 모형의 향상도는 최고 11.8이였으며, 개발된 모형에서 분류된 1~5유형까지 적용하여 청구된 자료 중 결핵이 아님을 예측할 경우, 민감도는 90.6%, 양성예측도는 96.1%, 정분류율은 87.6%로 나타나, 현재 질병관리본부에서 사용하는 청구2회 이상, 약제 2제 이상 모형(민감도 82.6%, 양성예측도 95%, 정분류율 80%)보다 우수한 모형인 것으로 나타났다.

• 벤처창업연구
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• 제6권2호
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• pp.133-147
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• 2011

본 연구에서는 최근 꾸준한 성장세를 보이고 있는 의료산업의 국내벤처기업에 대한 신용 평가를 위해 먼저 기업의 재무 요인과 비재무 요인을 구분하여 평가지표를 개발한 다음 Saaty(1980)의 계층분석과정(Analytic Hierarchy Process; AHP)방법론을 적용하여 각 지표의 중요도(가중치)를 산출함으로써 의료벤처기업의 신용평가모형을 제시한다. 재무요인의 상위지표로는 수익성, 안전성, 활동성, 성장성, 생산성을 선택하였고, 각 상위지표에 대해서는 2개씩의 하위지표를 정하여 모두 10개의 지표를 설정하였다. 또 비재무적 요인의 상위지표로는 경영자 능력, 기술성, 시장성, 사업성, 신뢰성의 5개 영역을 정하고, 각 영역에 대해 2-5개의 하위지표를 정하여 모두 17개의 지표를 설정하였다. 신용평가지표에 대한 평가를 위해 원주의료기기클러스터 내 소재하고 있는 금융기관 및 보증기관의 심사역을 대상으로 설문조사를 한 후 이를 분석하여 평가지표에 대한 가중치를 산출하였다.

• 보건행정학회지
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• 제18권4호
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• pp.85-110
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• 2008

In this study, we explore the long-term demand forecasting of high-price medical equipments based on logistic and Bass diffusion model. We analyze the specific pattern of each equipment's diffusion curve by interpreting the parameter estimates of Bass diffusion model. Our findings are as follows. First, ultrasonic imaging system, CT are in the stage of maturity and so, the future demands of them are not too large. Second, medical image processing unit is between growth stage and maturity stage and so, the demand is expected to increase considerably for two or three years. Third, MRI is in the stage of take-off and Mammmography X-ray system is in the stage of maturity but, estimates of the potential number of adopters based on logistic model is considerably different to that based on Bass diffusion model. It means that additional data for these two equipments should be collected and analyzed to obtain the reliable estimates of their demands. Fourth, medical image processing unit have the largest q value. It means that the word-of-mouth effect is important in the diffusion of this equipment. Fifth, for MRI and Ultrasonic system, q/p values have the relatively large value. It means that collective power has an important role in adopting these two equipments.

• 보건행정학회지
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• 제24권1호
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• pp.47-55
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• 2014

Background: Korea is considered to have an integrative health system where both western medicine and Korean (traditional) medicine are officially recognized and provided. Although Korean medicine has been covered by National Health Insurance over 20 years, equity in the utilization of Korean medical care has rarely been examined. Methods: We examined medical care utilization and expenditure of outpatient Korean medicine using panel fixed effects model to remove selection bias. Then we compared it with pooled ordinary least square (OLS) model. This study used Korea Health Panel data, which provides accurate information on out-of-pocket health care payment, including non-covered medical services. Results: Principal findings indicate that the frequency of the utilization of Korean medicine is related with unobservable individual choices different from western medicine, so the panel fixed effect model is appropriate. But pooled OLS model is better fitted for the expenditure of Korean medicine, after controlling for western medical care expenditure. After adjusting for the selection bias, socioeconomic status (income, education) was significantly associated with the expenditure of Korean medicine, but not with the frequency of the utilization of Korean medicine. Conclusion: This study shows that expenditure of Korean medicine utilization is inequitable across socioeconomic groups, which implies that health insurance coverage of Korean medicine is not sufficient.

• The Journal of Advanced Prosthodontics
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• 제12권1호
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• pp.33-37
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• 2020

PURPOSE. The purpose of this study is to evaluate the effects of type of magnet attachment and implant angulation in two implant overdenture models. MATERIALS AND METHODS. Magnet attachments used in this study were flat and dome types (MGT5515, MGT5520D, Dentium Co., Seoul, Korea). Two implants with keepers were inserted in the resin blocks at a distance of 24 mm. For the first model, the implants were parallel to the vertical and perpendicular to the horizontal; for the second model, both were angulated 5 degrees to the mesial; for the third model, both were angulated 10 degrees toward the mesial. The retentive force was measured in both vertical and lateral directions. Statistical analyses were performed using SPSS software version 22.0 (α=.05). RESULTS. The flat type magnet attachment showed the highest lateral retentive force in the 20° divergent group (P<.05) and the dome type magnet attachment showed the highest lateral retentive force in the parallel group (P<.05). The vertical and lateral retentive force of the dome type magnet attachment was greater than that of the flat type magnet attachment in every direction (P<.05). CONCLUSION. Within the limitations of this study, the dome shape magnet attachment can resist vertical and lateral retentive force more superiorly than the flat type magnet attachment, regardless of angle, in the mandibular two implant model.

• 대한의용생체공학회:의공학회지
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• 제41권5호
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• pp.195-202
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• 2020

Needle detection in ultrasound images is sometimes difficult due to obstruction of fat tissues. Accurate needle detection using continuous ultrasound (CUS) images is a vital stage of treatment planning for tissue biopsy and brachytherapy. The main goal of the study is classified into two categories. First, new detection model, i.e. D-Attention Unet, is developed by combining the context information of 3D medical data and CUS images. Second, the D-Attention Unet model was compared with other models to verify its usefulness for needle detection in continuous ultrasound images. The continuous needle images taken with ultrasonic waves were converted into still images for dataset to evaluate the performance of the D-Attention Unet. The dataset was used for training and testing. Based on the results, the proposed D-Attention Unet model showed the better performance than other 3 models (Unet, D-Unet and Attention Unet), with Dice Similarity Coefficient (DSC), Recall and Precision at 71.9%, 70.6% and 73.7%, respectively. In conclusion, the D-Attention Unet model provides accurate needle detection for US-guided biopsy or brachytherapy, facilitating the clinical workflow. Especially, this kind of research is enthusiastically being performed on how to add image processing techniques to learning techniques. Thus, the proposed method is applied in this manner, it will be more effective technique than before.

• 동의생리병리학회지
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• 제20권1호
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• pp.196-201
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• 2006

Electroacupuncture(EA) is commonly used in various diseases. In the present study, the effect of EA in the allergic mouse model was examined. Allergy is generated via immunological mechanism and non-immunological mechanism. Mast cells activated dy those mechanisms get to release various substances such as histamine, leukotrienes, prostaglandin, TNF-$\alpha$, IL-4, IL-6, etc. which induce allergic reactions and the following inflammatory responses. To evaluate the anti-allergic effects of EA, mortality, ear swelling response, vascular permeability and cytokine secretion were investigated in EA group and non-EA group of which mice were compound 48/80-induced allergy model or PCA model. Compound 48/80 induces allergic reaction via non-immunological mechanism and PCA model is generated through the same mechanism with immediate-type(Type1) allergic reaction, one of immunological allergic reactions. EA inhibited compound 48/80-induced ear swelling response but did not inhibit the systemic anaphylaxis. EA also inhibited passive cutaneous anaphylaxis(PCA) activated dy anti-dinitrophenol IgE. In addition, EA inhibited IL-6 and TNF-$\alpha$ secretion from 48 h PCA in mice. These results indicate that EA may be used for the treatment of mast cell-mediated allergic diseases, especially immediate-type(Type 1) allergy and non-immunologically mediated allergy.

• Imaging Science in Dentistry
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• 제49권1호
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• pp.19-26
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• 2019

Purpose: It has been proposed that using new prediction methods, such as neural networks based on dental data, could improve age estimation. This study aimed to assess the possibility of exploiting neural networks for estimating age by means of the pulp-to-tooth ratio in canines as a non-destructive, non-expensive, and accurate method. In addition, the predictive performance of neural networks was compared with that of a linear regression model. Materials and Methods: Three hundred subjects whose age ranged from 14 to 60 years and were well distributed among various age groups were included in the study. Two statistical software programs, SPSS 21 (IBM Corp., Armonk, NY, USA) and R, were used for statistical analyses. Results: The results indicated that the neural network model generally performed better than the regression model for estimation of age with pulp-to-tooth ratio data. The prediction errors of the developed neural network model were acceptable, with a root mean square error (RMSE) of 4.40 years and a mean absolute error (MAE) of 4.12 years for the unseen dataset. The prediction errors of the regression model were higher than those of the neural network, with an RMSE of 10.26 years and a MAE of 8.17 years for the test dataset. Conclusion: The neural network method showed relatively acceptable performance, with an MAE of 4.12 years. The application of neural networks creates new opportunities to obtain more accurate estimations of age in forensic research.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제12권5호
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• pp.229-236
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• 2023

3D 출력된 의료용 임플란트(implant) 부품은 보통 표면에 결함이 발생되므로, 출력 후 표면을 검사하는 과정이 필요하다. 자동화된 표면 검사를 수행하기 위해서는 임플란트를 3D 스캔하여 점군(point cloud)과 같은 스캔 모델로 복원하는 방법이 효과적이다. 스캔 모델을 구성할 때, 임플란트는 일반적인 3D 출력 제조 부품과 다른 특성들을 가지므로, 임플란트의 형태와 재료의 특성에 대한 고려가 필요하다. 본 논문에서는 의료용 임플란트 부품의 한 종류인 금속 bone-plate의 3D 출력물에 대해 스캔 모델로 복원하는 방법을 제안한다. 다각도의 시점에서 3D 스캔을 수행하여 다수의 부분 스캔 데이터를 생성한 뒤, 이들에 대해 정렬(alignment)과 정합(merging)을 수행하여 스캔 모델로 복원한다. 또한, 실험을 통해 스캔 모델로 복원하는 과정을 보인다.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 2004년도 추계학술대회 및 총회
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• pp.414.2-414.2
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• 2004