• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1992년도 춘계학술대회
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• pp.141-143
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• 1992

• 한국의학물리학회지:의학물리
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• 제29권4호
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• pp.123-136
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• 2018

The complex dose distribution and dose transfer characteristics of intensity-modulated radiotherapy increase the importance of precise beam data measurement and review in the acceptance inspection and preparation stages. In this study, we propose a process map for the introduction and installation of high-precision radiotherapy devices and present items and guidelines for risk management at the acceptance test procedure (ATP) and commissioning stages. Based on the ATP of the Varian and Elekta linear accelerators, the ATP items were checked step by step and compared with the quality assurance (QA) test items of the AAPM TG-142 described for the medical accelerator QA. Based on the commissioning procedure, dose quality control protocol, and mechanical quality control protocol presented at international conferences, step-by-step check items and commissioning guidelines were derived. The risk management items at each stage were (1) 21 ionization chamber performance test items and 9 electrometer, cable, and connector inspection items related to the dosimetry system; (2) 34 mechanical and dose-checking items during ATP, 22 multileaf collimator (MLC) items, and 36 imaging system items; and (3) 28 items in the measurement preparation stage and 32 items in the measurement stage after commissioning. Because the items presented in these guidelines are limited in terms of special treatment, items and practitioners can be modified to reflect the clinical needs of the institution. During the system installation, it is recommended that at least two clinically qualified medical physicists (CQMP) perform a double check in compliance with the two-person rule. We expect that this result will be useful as a radiation safety management tool that can prevent radiation accidents at each stage during the introduction of radiotherapy and the system installation process.

• Korean Journal of Acupuncture
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• 제26권1호
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• pp.51-60
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• 2009

Objectives : It is considered not easy to diagnose the condition of acupoints or meridians. Oriental Medical instruments have rarely complied with Oriental Medical diagnostic/therapeutic theories. The aim of this study was to develop a system which measures meridian electric potential(MEP) in proportion to bio-electric charge for the purpose of Oriental Medical diagnosis. Method : To evaluate a meridian energy measurement system(MEMS), we carried out a performance test. For significance test, we conducted a clinical trial which measured the MEP of ST36(Chok-samni) on Stomach Meridian(ST). Results & Conclusions : We could evaluate the balance or the imbalance of the MEPs on the left/right ST36. Also, through the comparison of MEPs before and after meals, we could identify the correlation between the MEP and the condition of internal organs. Namely, MEP reflects the condition of acupoints/meridians and internal organs, therefore, we propose this new method for measuring and analyzing the condition of meridians and acupoints for Oriental Medical diagnosis.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2005년도 추계종합학술대회
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• pp.521-524
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• 2005

In order to measure ECG in daily life, a new ECG measurement method on bed was developed. The provided method does not require any direct conductive contact between the instrument and bare skin, so that it does not cause the uncomfortable feel of touch and the possible skin trouble which are typical shortcomings of the conventional conductive contact ECG measurement. The provided method utilized an array of high-input-impedance active electrodes fixed on the mattress and an indirect-skin-contact ground made of a large conductive textile sheet and laid on lower area of the mattress. A thin cotton bedcover covered the mattress, the electrodes, and the conductive textile and subjects lay on the mattress over the bedcover. ECG was obtained successfully. However its signal quality is lower and the motion artifact is larger than direct-contact measurement. Careful measurement setup was needed to reduce the motion artifact originated from variation in static electricity. From the ECG obtained by the provided method, R-peak could be discriminated easily and the information about the position and the posture of the subject could be obtained.

• 핵의학기술
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• 제19권2호
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• pp.102-107
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• 2015

Purpose Serum Thyroglobulin measurement is a major tool for the follow-up of differentiated thyroid cancer (DTC) patients. Thyroglobulin is Normal thyroid tissue, or thyroid cancer tissue produced only. Thyroid hormone to a halt without Tg differentiation of thyroid cancer recurrence just by measuring how to decide whether there was increasing expectations if I can do it instead. Therefore, in excellent sensitivity Tg new inspection of the functional sensitivity by measuring the looked to evaluate the usefulness of reagents. Thyroidectomy is measuring the numbers Tg (total thyroidectomy) remaining thyroid ablation and radioactive iodine (radioactive iodine remnant ablation, RRA) DTC in patients being diagnosed with or help predict the remaining early detection of thyroid cancer recurrence. Materials and Methods Agent that I'm currently using Tg of the measurements of low clinical specimen for a second drainage of the three (0.08 0.17, 0.98, ng/mL) within the scope of the dilute magnification (2, 4, 8, 16, 32 times) by dilute Intraassy (n=10) and Interassay (n=10) out in no time. Concentration value according to the coefficient of variation and the mean and standard deviation of each measurement (Coefficient of variation, CV) the absolute value of the measured values that corresponds to 20 percent target a coefficient of variation of CV Find the value of the concentration of the functional sensitivity measurement did. Also, analytical sensitivity with recovery rates, Dilution test inspections, and interrelationship, compared. Results Sensitivity is an excellent analytical sensitivity within the prosecutor kit Tg 0.006 ng/mL, and core analytical sensitivity, conducted by the 0.006 ng/mL to same conclusion. Be rather high to 142 percent recovery rate was 60 to measurement and functional sensitivity, 0.01766 ng/mL(Intraassay n=10) was measured at. CBC is relatively good correlation as ($R^2=0.949$) the correlation. Conclusion Recently ultrasensitive thyroglobulin this clinically important indicators of the previous kit and demands are lower than sensitivity to the measurement results. Therefore, ultrasensitive thyroglobulin test is correlated that there would be useful in value in nuclear medicine the thyroid gland.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2008년도 Asian Magnetics Conference
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• pp.250.1-250.1
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• 2008

• 한국의학물리학회지:의학물리
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• 제26권1호
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• pp.1-5
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• 2015

의료용 및 산업용으로 활용하기 위한 C-밴드형 콤팩트 선형가속기의 개발이 동남권원자력의학원에서 진행되고 있다. 본 논문에서는 선형가속기 시작품에서 발생한 전자빔의 출력 측정 결과를 보고하고자 한다. 출력 측정은 물흡수선량에 대해 교정된 Exradin-A10 마커스형 평행평판형 전리함을 사용하여 물속 기준 깊이에서 IAEA TRS-398 프로토콜에 따라 흡수선량율을 결정하는 과정으로 진행되었다. 전자선 에너지가 낮은 점으로 인하여 선질지표($R_{50}$)은 필름 측정법을 써서 근사적으로 결정하였다. 결과로서 단위 펄스 진동수당의 선형가속기 전자빔의 출력은 $17.0cGy/(min{\cdot}Hz$로 나타났다. 본 연구의 결과는 개발 중인 전자가속기의 성능 평가 자료로 활용될 것이다.

• 핵의학기술
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• 제14권2호
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• pp.100-103
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• 2010

$^{18}F$-FDG PET 검사는 포도당 대사를 이용하여 전신의 종양을 평가하는 검사로 전처치 과정에서 혈당 측정의 중요성이 매우 높다. 혈당 수치가 높은 상태에서 FDG를 투여하면 FDG와 혈중 포도당이 세포 내 흡수에 서로 경쟁하게 되고 종양으로의 FDG 섭취가 감소되어 정확한 검사가 되지 않을 가능성이 있다. 혈당 측정에 사용되는 혈당 측정 검사지는 경우에 따라 모세혈관혈 전용 측정 검사지와 모세혈관혈과 정맥혈을 모두 측정 가능한 범용 측정 검사지로 구분되어 있는데, 정확한 혈당 측정 검사지(스트립)의 사용에 따른 혈당 수치의 차이를 비교 분석 하였다. 연구 대상은 2010년 3월부터 4월까지 서울아산병원 핵의학과에서 $^{18}F$-FDG whole body PET 검사를 시행한 환자 중 46명(남자: 32명, 여자: 14명, 평균연령 $57.3{\pm}12.3$세) 을 연구의 대상으로 하였다. 실험기기는 Abbott사의 Optium Xceed혈당 측정기를 이용하였고, 모세혈관혈과 정맥혈을 모두 측정 가능한 범용 측정 검사지를 사용하여 동일 환자의 모세혈관혈과 정맥혈의 혈당 수치의 차이를 분석하였다. 또한, 모세혈관혈 전용 측정 검사지를 사용하여 동일 환자의 모세혈관혈과 정맥혈의 혈당 수치의 차이를 비교 분석하였다. 분석방법은 MINITAB 통계 프로그램을 이용하여 paired t-test 검정을 시행하였다. 모세혈관혈과 정맥혈을 모두 측정 가능한 범용 측정 검사지로 측정한 동일 환자의 모세혈관혈과 정맥혈의 혈당 수치는 각각$95.2{\pm}12.4$ mg/dL, $104.1{\pm}14.4$ mg/dL (t=8.0, p<0.001)로 통계적으로 유의한 차이가 있었다. 모세혈관혈 전용 측정 검사지로 측정한 동일 환자의 모세혈관혈과 정맥혈의 혈당 수치는 각각 $91.5{\pm}13.6$ mg/dL, $108.1{\pm}16.2$ mg/dL (t=9.2, p<0.001)로 통계적으로 유의한 차이가 있었다. 선행연구에 의하면 모세혈관혈과 정맥혈의 혈당 수치는 여러 가지 이유로 인해 차이가 있는 것으로 보고 되었고 본 연구의 결과도 유사한 차이를 확인하였다. $^{18}F$-FDG PET 검사 전에 혈당 수치를 측정할 때 모세혈관혈 전용 측정 검사지로 정맥혈의 혈당을 측정하는 것은 부정확한 혈당 수치를 측정할 수 있으므로 주의해야 할 것이다. 그러므로 적합한 측정 검사지와 규정된 측정절차를 이행하는 것이 측정 편차를 줄일 수 있어 PET 검사의 전처치를 보다 명확하게 확인할 수 있을 것이다. 또한, 혈당 측정 시에 혈액 채취 부위를 모세혈관 또는 정맥혈관 중에서 항상 동일한 부위에서 측정하는 등의 표준화 과정이 필요할 것이다.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.225-227
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• 2002

In order to improve the accuracy of charged-particle radiation therapy, the beam energy was measured precisely using a TOF-system, and the range using a counter telescope system. A Si detector and a Ge detector were used to estimate the range straggling as a $\Delta$E and an E detector, respectively, because they have good energy resolution and the output pulse heights don't depend on the atomic number of detected particles. The results were compared with the theoretical values by a calculation code.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2006년 제4회 한국유체공학학술대회 논문집
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• pp.145-146
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• 2006

Recently, the next-generation advanced flow visualization techniques such as holographic PIV, dynamic PIV, echo-PIV, micro/nano-PIV, and X-ray PIV have been introduced. These advanced measurement techniques have a big potential as the core technology for analyzing outmost thermo-fluid flows in future. These would be indispensable in solving complicated thermo-fluid flow problems not only in the industrial fields such as automotive, space, electronics, aero- and hydro-dynamics, steel, and information engineering, but also in the research fields of medical science, bio-medical engineering, environmental and energy engineering etc. Especially, NT (Nano Technology) and BT (Bio Technology) strongly demand these advanced measurement techniques, because it is impossible for conventional measurement methods to observe most complicated nano- and bio-fluidic phenomena. In this presentation, the basic principle of these high-tech flow visualization techniques and their practical applications which cannot be resolved by conventional methods, such as blood flows in a micro-tube, in vivo analysis of micro-circulation, and flow around a living body will be introduced as a blue ocean strategy.