• Title/Summary/Keyword: Medical measurement

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The Prognostic Role of B-type Natriuretic Peptide in Acute Pulmonary Thromboembolism (급성 폐혈전색전증 환자에서 예후 인자로서 혈중 BNP의 의의)

  • Lee, Su Jin;Lee, Jae Hyung;Park, Ji Young;Jo, Woo Sung;Kim, Ji Eun;Kim, Ki Uk;Park, Hye Kyung;Kim, Yun Seong;Lee, Min Ki;Park, Soon Kew
    • Tuberculosis and Respiratory Diseases
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    • v.60 no.5
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    • pp.540-547
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    • 2006
  • Background : Vital stability and right side heart failure are major prognostic factors of acute pulmonary thromboembolism. While it is important to recognize right side heart failure, it is often difficult in real practice. Recently, several studies have described early diagnostic tools for detecting right side heart failure including echocardiography and biochemical markers. This study, we evaluated the prognostic role of the B-type natriuretic peptide (BNP) in an acute pulmonary thromboembolism. Methods : Thirty-four patients with a diagnosis of acute pulmonary thromboembolism were enrolled in the study. The BNP levels were measured and echocardiography was performed at the Emergency Department. Data on the prognostic factors including ventilatory support, vital stability, pulmonary artery pressure, degree of tricuspid valve regurgitation, complications and death was collected from the patients' medical records. The patients with an acute pulmonary thromboembolism were divided into two groups based on the vital stability and the BNP level and the cutoff values and prognostic factors of the two groups were compared. Results : The predictors of the vital stability that influence the prognosis of patients with acute pulmonary thromboembolism were the BNP level, ventilatory support and death. The plasma BNP levels showed a strong correlation with the vital stability, ventilatory support, thrombolytic therapy and death. When the BNP cutoff level was set to 377.5 pg/dl in a ROC curve, the sensitivity and the specificity for differentiating between the groups with stable or unstable vital signs was 100% and 90%, respectively. Conclusion : This study indicates that a measurement of the plasma BNP levels may be a useful prognostic marker in patients with an acute pulmonary thrombo-embolism.

The Complementary Role of FEV6 in Bronchodilator Reversibility Test for the Old Age (노인환자의 기도가역성 검사에서 FEV6의 보완적 지표로서의 역할)

  • Kim, Sae Hee;Lee, Yang Deok;Lee, Jung Yun;Cho, Yong Seon;Na, Dong Jip;Han, Min Soo
    • Tuberculosis and Respiratory Diseases
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    • v.61 no.3
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    • pp.227-232
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    • 2006
  • Background: In the measurement of bronchodilator reversibility, the forced expiratory volume in one second($FEV_{1}$) and the forced vital capacity(FVC) are commonly used parameters and recommended criteria for the reversibility requiring an increase of more than 200ml and 12% above the baseline, respectively. However, aged patients do not often meet the criteria of an increase in volume(>200ml) even though the medical history of that patient is adequate for asthma. This study investigated the role of the forced expiratory volume in six seconds($FEV_{6}$) in the bronchodilator reversibility test in elderly patients. Methods: A total of 236 patients more than 65 years of age with a $FEV_{1}$/FVC ratio<80% were enrolled in this study. The bronchodilator revesibility tests were examined. With the setting $FEV_{1}$ as the baseline, the patients were divided into three groups; Group I : $$FEV_{1}{\geq_-}80%$$ of the predicted value, Group II : 60%<$FEV_{1}$<80% of the predicted value, Group III : $$FEV_{1}{\leq_-}60%$$ of the predicted value. Results: Positive reversibility in the $FEV_{1}$, $FEV_{6}$, and FVC was in 33(14.0%), 49(20.8%) and 55(23.3%). However, Group III presented with reversibility in the $FEV_{1}$, $FEV_{6}$, and FVC in 15(22.4%), 30(44.8%) and 32(47.8%) respectively. Conclusions: The $FEV_{6}$ might be used as a complementary parameter in bronchodilatror reversibility in elderly patients. However, more study will be needed to determine the usefulness of $FEV_{6}$ in bronchodilator reversibility test.

Status of a national monitoring program for environmental radioactivity and investigation of artificial radionuclide concentrations (134Cs, 137Cs, 131I) in rivers and lakes (방사성물질 측정망 현황 및 하천·호소 내 인공방사성물질 (134Cs, 137Cs, 131I) 조사)

  • Kim, Jiyu;Jung, Hyun-ji;An, Mijeong;Hong, Jung-Ki;Kang, Taegu;Kang, Tae-Woo;Cho, Yoon-Hae;Han, Yeong-Un;Seol, Bitna;Kim, Wansuk;Kim, Kyunghyun
    • Analytical Science and Technology
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    • v.28 no.6
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    • pp.377-384
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    • 2015
  • A survey of the artificial radionuclides in rivers and lakes was conducted to investigate their levels in surface water. Water samples were collected at 60 points and analyzed by gamma-ray spectrometry with a measurement time of 10,000 seconds for 134Cs, 137Cs, and 131I. The obained values were lower than MDA for all points, except one point for 131I that was 0.533±0.058 Bq/L. 131I is known as a radioactive material that occurs frequently in sewage treatment plants. Because it is often used for medical treatments and subject to spreading into the environment due to the excretion from the patients. For the point where 131I was detected, we conducted additional investigation on the upstream river point and the effluent points of nearby sewage treatment plant to find the source of 131I. 131I was not detected at the upstream points of one of the upstream sewage treatment plants but found at the downstream points with the level being 0.257±0.034 to 0.799±0.051 Bq/L, proving the sewage treatment plant was the 131Isource.

Study on Ego states in the view of Transactional analysis, Coping style and Health states of Nursing Students (상호교류분석으로 본 간호학생의 자아상태와 스트레스 대처방법 및 건강상태에 관한 연구)

  • Won, Jeong-Sook;Kim, Jeong-Hwa
    • Journal of East-West Nursing Research
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    • v.7 no.1
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    • pp.68-81
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    • 2002
  • The purpose of this study is to analyze the type of ego states and stress coping style on female college students who are in the course of nursing study. This study is performed in the view of Transactional Analysis and designed to scrutinize descriptive correlations between the type of ego states and stress coping style. The subject is consists of 144 freshmen and sophomore, 138 junior and senior students group, who are students of K nursing college located in Seoul. The sampling investigation period is on Sept. 14, 2002 to Oct. 26, 2002. The measuring instrument used for Transactional Analysis ego state is 50 items Ego-gram research paper devised by Dusay(1997). For studying coping style, Folkman & Lazarus's measurement(1984) was adopted, which is translated and modified by Han, and Oh,(1990). Health states is adopted by standardized health inspecting instrumental table (Cornell Medical Index:CMI) which is designed for Korean people by Ko and Park(1980) Statistic average and standard deviation were generated by using SPSS PC+, t=test and Pearson correlation. The results were as follows: 1) In the type of ego states on both groups indicated the arithmetic apex NP(maximum value), then the point A was high and the data made a down slope to point AC. In the comparison to type of ego states between two groups, only at point CP, the data value of upper year students represented higher than that of lower year ones by c(t=2.28, p=.023). 2) Stress coping style of whole students were highly and affirmatively dedicated to research. Especially hopeful aspect(t=.67, p=.05), relaxation of tension(t=-2.16, p=.03) made significant difference each other in the view of arithmetic calculation. 3) In view of nursing students' physical health states, there is significant difference in past history(t=2.50, p=.013) and in case of mental health states, there are considerable discrepancies between lower group(73.52) and upper group(75.11)(p<.05). In view of all field, state of tension(t=2.13, p=.048) has difference. 4) While verifying coping style in terms of ego states level between lower and upper students group, In type CP, high level ego states group indicated significant difference on stress coping style area than low leveled group and made such sequences as the central point of problem, In type NP, sequences such as the central point of problem, In type A, the central point of problem, In type FC, hopeful aspect and In type AC, hopeful aspect and indifference were derived significantly different (p<.05). 5) While verifying health state differences in the level of lower and upper ego states, In type FC, low level group(150.29) marked higher point than upper group(145.19), there is remarkable discrepancy and so did whole health state(p=.014), In type AC both mental state(p=.000) and whole health state (p=.015) showed differences. 6) When analyzing correlations between whole students' ego states, copying style and health state, all type of ego state showed differences(p<.001). In correlations between ego state and health state, in type FC physical state had an apex and there are inverse correlations among the other types. Especially, type FC showed inverse correlations with great discrepancies(p<.05). In mental state, type NP(${\gamma}=.198$, p<.001) and type A(${\gamma}=.166$, p<.05) represented straight correlations with remarkable differences. Especially, In type AC showed inverse correlations(${\gamma}=.282$, p<.001). In case of correlations between copying style and health state, indifference(${\gamma}=-.157$) and relaxation of tension(${\gamma}=-.158$) presented great difference(p<.05). In mental state, central point of problem and search for social support showed straight correlations with great discrepancies(p<.05), hopeful aspect and indifference showed inverse correlations with considerable differences(p<.001).

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Analysis of Age-related Distribution of the Tracheal Diameter and Cross-sectional Area Among Koreans -Compuerized Tomographic Measurement- (한국인의 연령별 기관 내경 및 단면적 분포에 대한 분석 -흉부전산화단층촬영을 이용한 측정-)

  • Lee, Gun;Kim, Dae-Sik;Moon, Seung-Chul;Koo, Won-Mo;Yang, Jin-Young;Lee, Hyeon-Jae;Lim, Chang-Young;Han, Hyeon;Kim, Kwang-Ho;Sun, Kyung
    • Journal of Chest Surgery
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    • v.32 no.5
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    • pp.442-447
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    • 1999
  • Introduction: Understanding the normal distribution of the tracheal diameter and crross- sectional area is one of the key elements in the management of various tracheal pathologies or tracheal reconstruction for the patients in growing age. However, data for Korean standard has been lacking. This study was designed to analyze retrospectively the distribution of tracheal diameter and cross-sectional area in young Koreans, which can afford fundamental data for the management of tracheal diseases. Material and Method: Of the patients who underwent computerized tomogram of the chest between May 1996 and August 1998, one hundred six young patients(age range: 0-20 years) were included. Patients with any conditions which might affect the tracheal cross-sectional area or diameter, such as tracheal disease, previous operation, mediastinal tumor, or obstructive lung disease were excluded from the study. Gender distribution was 69 males and 37 females. Tracheal diameters, anterior-posterior and transverse, were measured at the level of the thoracic inlet(level I) and the aortic arch(level II). Types of the trachea were divided into round, oval, or horseshoe shaped on cross-sectional view, and the dimension was calculated by using the equation of A=1/4$\pi$ab(A; area, $\pi$; 3.14, a; anterior-posterior diameter, b; transverse diameter). We analyzed the distribution of the diameter at each level and compared the cross-sectional area with respect to age and gender. A p-value lower than 0.05 wa considered significant. Result: The trachea of patients less than 5 years old were round in shape at both of level I and II, and no differences in cross-sectional area was observed between the levels(p=NS). As the age increased, the trachea become oval in shape at level I while it remained round in shape at level II(p=0.020). The tracheal diameter and cross-sectional area increased as the age increased with a linear correlation(r>0.9). In patients less than 5 years of age, female patients showed larger cross-sectional area than male patients (p=0.020), and it was reversed in patients older than 15 years of age(p=0.002). Conclusion: From the above results, we suggest chest computerized tomogram as a safe and reliable tool in measuring the tracheal diameter and cross-sectional area. We also provide the data as a standard for distribution of the tracheal diameter and cross-sectional area in young Korean population.

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Snow Influence on the Chemical Characteristics of Winter Precipitation (강설이 겨울철 강수의 화학적 특성에 미치는 영향)

  • Kang, Gong-Unn;Kim, Nam-Song;Oh, Gyung-Jae;Shin, Dae-Yewn;Yu, Du-Cheol;Kim, Sang-Baek
    • Journal of Korean Society of Environmental Engineers
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    • v.29 no.1
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    • pp.113-125
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    • 2007
  • To know the differences in ionic compositions in rain and snow as well as snow influence on the chemical characteristics of winter precipitation, precipitation samples were collected by the wet-only automatic precipitation sample, in winter(November-February) in the Iksan located in the northwest of Chonbuk from 1995 to 2000. The samples were analyzed for concentrations of water-soluble ion species, in addition to pH and electrical conductivity. The mean pH of winter precipitation was 4.72. According to the type of winter precipitation, the mean pH of rain was 4.67 and lower than 5.05 in snow. The frequencies of pH below 5.0 in rain were about 73%, while those in snow were about 30%. Snow contained 3 times higher concentrations of sea salt ion components originated from seawater than did rain in winter, mainly $Cl^-,\;Na^+$, and $Mg^{2+}$. Neglecting sea salt ion components, $nss-SO_4^{2-}$ and $NO_3^-$ were important anions and $NH_4^+$ and $nss-Ca^{2+}$ were important cations in both of rain and snow. Concentrations of $nss-SO_4^{2-}$ was 1.3 times higher in rain than in snow, while those of $nss-Ca^{2+}$ and $NO_3^-$ were 1.5 and 1.3 times higher in snow, respectively. The mean equivalent concentration ratio of $nss-SO_4^{2-}/NO_3^-$ in winter precipitation were 2.4, which implied that the relative contribution of sulfuric and nitric acids to the precipitation acidity was 71% and 29%, respectively. The ratio in rain was 2.7 and higher than 1.5 in snow. These results suggest that the difference of $NO_3^-$ in rain and snow could be due to the more effective scavenging of $HNO_3$ vapor than particulate sulfate or nitrate by snow. The lower ratio in snow than rain is consistent with the measurement results of foreign other investigators and with scavenging theory of atmospheric aerosols. Although substantial $nss-SO_4^{2-}$ and $NO_3^-$ were observed in both of rain and snow, the corresponding presence of $NH_4^+,\;nss-Ca^{2+},\;nss-K^+$ suggested the significant neutralization of rain and snow. Differences in chemical composition of non-sea salt ions and neutralizing rapacity of $NH_4^+,\;nss-Ca^{2+}$, and $nss-K^+$ between rain and snow could explain the acidity difference of rain and snow. Snow affected that winter precipitation could be less acidic due to its higher neutralizing rapacity.

The Effect of Meta-Features of Multiclass Datasets on the Performance of Classification Algorithms (다중 클래스 데이터셋의 메타특징이 판별 알고리즘의 성능에 미치는 영향 연구)

  • Kim, Jeonghun;Kim, Min Yong;Kwon, Ohbyung
    • Journal of Intelligence and Information Systems
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    • v.26 no.1
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    • pp.23-45
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    • 2020
  • Big data is creating in a wide variety of fields such as medical care, manufacturing, logistics, sales site, SNS, and the dataset characteristics are also diverse. In order to secure the competitiveness of companies, it is necessary to improve decision-making capacity using a classification algorithm. However, most of them do not have sufficient knowledge on what kind of classification algorithm is appropriate for a specific problem area. In other words, determining which classification algorithm is appropriate depending on the characteristics of the dataset was has been a task that required expertise and effort. This is because the relationship between the characteristics of datasets (called meta-features) and the performance of classification algorithms has not been fully understood. Moreover, there has been little research on meta-features reflecting the characteristics of multi-class. Therefore, the purpose of this study is to empirically analyze whether meta-features of multi-class datasets have a significant effect on the performance of classification algorithms. In this study, meta-features of multi-class datasets were identified into two factors, (the data structure and the data complexity,) and seven representative meta-features were selected. Among those, we included the Herfindahl-Hirschman Index (HHI), originally a market concentration measurement index, in the meta-features to replace IR(Imbalanced Ratio). Also, we developed a new index called Reverse ReLU Silhouette Score into the meta-feature set. Among the UCI Machine Learning Repository data, six representative datasets (Balance Scale, PageBlocks, Car Evaluation, User Knowledge-Modeling, Wine Quality(red), Contraceptive Method Choice) were selected. The class of each dataset was classified by using the classification algorithms (KNN, Logistic Regression, Nave Bayes, Random Forest, and SVM) selected in the study. For each dataset, we applied 10-fold cross validation method. 10% to 100% oversampling method is applied for each fold and meta-features of the dataset is measured. The meta-features selected are HHI, Number of Classes, Number of Features, Entropy, Reverse ReLU Silhouette Score, Nonlinearity of Linear Classifier, Hub Score. F1-score was selected as the dependent variable. As a result, the results of this study showed that the six meta-features including Reverse ReLU Silhouette Score and HHI proposed in this study have a significant effect on the classification performance. (1) The meta-features HHI proposed in this study was significant in the classification performance. (2) The number of variables has a significant effect on the classification performance, unlike the number of classes, but it has a positive effect. (3) The number of classes has a negative effect on the performance of classification. (4) Entropy has a significant effect on the performance of classification. (5) The Reverse ReLU Silhouette Score also significantly affects the classification performance at a significant level of 0.01. (6) The nonlinearity of linear classifiers has a significant negative effect on classification performance. In addition, the results of the analysis by the classification algorithms were also consistent. In the regression analysis by classification algorithm, Naïve Bayes algorithm does not have a significant effect on the number of variables unlike other classification algorithms. This study has two theoretical contributions: (1) two new meta-features (HHI, Reverse ReLU Silhouette score) was proved to be significant. (2) The effects of data characteristics on the performance of classification were investigated using meta-features. The practical contribution points (1) can be utilized in the development of classification algorithm recommendation system according to the characteristics of datasets. (2) Many data scientists are often testing by adjusting the parameters of the algorithm to find the optimal algorithm for the situation because the characteristics of the data are different. In this process, excessive waste of resources occurs due to hardware, cost, time, and manpower. This study is expected to be useful for machine learning, data mining researchers, practitioners, and machine learning-based system developers. The composition of this study consists of introduction, related research, research model, experiment, conclusion and discussion.

An Experimental Study on Internal Decontamination Radiocobalt (Radiocobalt의 체내 오염(汚染)에 대(對)한 제염효과(除染效果))

  • Chung, In-Yong;Kim, Tae-Hwan;Chung, Hyun-Woo;Chin, Soo-Yil;Yun, Taik-Koo
    • Journal of Radiation Protection and Research
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    • v.13 no.1
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    • pp.31-41
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    • 1988
  • In case of the acute intake of radionuclide, an early medical treatment may be necessary, but the little is established the procedures to decontaminate the victims of internal contamination in Korea. The purpose of the present investigation is to study chemical agents to remove radiocobalt from the victims and to provide a more reliable procedure for the treatment. The removals of radiocobalt from the NIH-CGP)mice injected intraperitoneally with $1{\mu}Ci$ of $^{58}Co$ as $CoCl_2$ were investigated with doses of either $CaNa_3$ DTPA 8.4mg/0.2ml saline, $CoNa_3$ DTPA 8.4mg/0.2ml saline, or saline 5ml. The radioactivity was determined by MCA and Ge-detector on 4, 8, 12, 48 hours and 7 days for the whole body, organ distribution and urine excretion. Six mice per each group were sacrificed for the measurement of cobalt retention in the parenchymal tissue. The cobalt trisodium chelate had a pronounced effect on reducing the whole body retention and increasing the excretion rate. Regarding to the systemic protective effects, $CoNa_3$ DTPA, $CaNa_3$ DTPA and saline were effected significantly in order. In conclusion, the extrapolations from these results to human were suggested that the rapid administration of cobalt trisodium chelate and an amount of saline to the contaminated person after internal contamination of radiocobalt were markedly increasing the decontamination effects.

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Immunogenicity and Protective Effectiveness of Japanese Encephalitis Vaccine: A Prospective Multicenter Cohort Study (일본뇌염 예방접종 후 면역원성 및 중화항체 지속률에 관한 조사: 전향적 다기관 코호트 연구)

  • Kim, Dong Hyun;Hong, Young-Jin;Lee, Hoon-Jai;Choi, Bo-Yul;Kim, Chang Hwi;Park, Jae Ock;Kang, Jin Han;Choi, Byung Joon;Kim, Jong Hyun;Ahn, Young Min;Ju, Young Ran;Jeong, Young Eui;Han, Myung Guk
    • Pediatric Infection and Vaccine
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    • v.20 no.3
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    • pp.131-138
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    • 2013
  • Purpose: This study aimed to study the antibody response of Japanese encephalitis vaccination in children using different kinds of vaccines (inactivated vaccine, live attenuated vaccine or interchanged) and evaluate the effectiveness of the vaccines to provide the basis of efficient immunization schedule of Japanese encephalitis. Methods: Measurement of the neutralization antibody (NTAb) titers following Japanese encephalitis vaccination using different vaccines for 170 children, 2-6 year of age, who visited six university hospitals and are confirmed by immunization records. Results: Among 170 children who were given primary immunization on Japanese encephalitis, 103 children were given inactivated vaccine, 64 children were given live attenuated vaccine and 3 children were given interchangeably. NTAb titers were more than 1:10 in all children of three groups. The geographic mean antibody titer was 322 in inactivated vaccine group and 266 in live attenuated vaccine group. However, there was no significant difference between two groups. In both groups, the NTAb titer showed the peak at 1-4 months after the third immunization and declined. The NTAb titers of three children who were given two kinds of vaccines alternately were 1:135, 1:632, and 1:2511, respectively. Conclusion: According to the results of this study in children younger than 6 years old, there is no significant difference in effectiveness between inactivated and live attenuated vaccines. However, further studies for the changes of antibody titers for a longer period of time on larger population are required.

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Sick Building Syndrome in 130 Underground Workers (지하상가 근무자의 건강 장애에 관한 실태조사)

  • Joo, Ree;SaKong, Joon;Chung, Jong-Hak;Park, Sang-Whan;Kim, Dong-Hee;Kim, Dong-Min;Choi, Eun-Kyong;Cho, Hyun-Geon
    • Journal of Yeungnam Medical Science
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    • v.15 no.2
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    • pp.325-340
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    • 1998
  • A cross-sectional study was conducted to evaluate the relationship between sick building syndrome(SBS) and the environmental factors affecting SBS on 130 underground workers and 60 controls. The study consisted of 1) a review of environmental condition 2) measurement of temperature, $O_2$, $CO_2$, CO, and formaldehyde and 3) a questionnaire survey of symptom prevalence and perception of environmental conditions using indoor Air Quality questionnaire recommended by National Institute for Occupational Safety and Health. Bronchitis and dust allergy were more prevalent in underground workers significantly(p < 0.05). Among the 18 symptoms related to the indoor air pollution, the experience rate of dry, itching or irritated eyes, sore or dry throat, chest tightness, tired or strained eyes and dry or itchy skin symptom was significantly different between the underground workers and controls. The diagnostic criteria of SBS was defined as at least 1 symptom is experienced 1-3 times a week during the last 1 month among 18 indoor air pollution related symptoms which can be relieved by moving out of the underground. Applying the criteria, the mean symptom score was significant higher in underground workers than controls significantly (p < 0.05). These resalts indicated that underground workers are under inappropriate ergonomic and physical condition and inadequate ventilation. Their experience rate of symptoms related to indoor air pollution and prevalence of SBS was significantly higher than controls. To reduce the prevalence of SBS of underground workers, the surveillance system of indoor air quality, restriction of using fuel in underground and legislative regulations for the environment are needed to establish a better indoor air quality. Early detection, treatment and prevention of SBS through medical attention is also needed.

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