• 제목/요약/키워드: Medical laboratory science

검색결과 1,802건 처리시간 0.035초

Transgene Expression of Biologically Active Human Follicle-Stimulating Hormone in Milk and Histological Analysis

  • Myoung-Ok Kim;Kil-Soo Kim;Eun-Ju Lee;Sung-Hyun Kim;Jun-Hong Park;Kyoungin-Cho;Boo-Kyung Jung;Hee-Chul Kim;Sol-ha Hwang
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2004년도 춘계학술발표대회
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    • pp.214-214
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    • 2004
  • Follicle stimulating hormone (FSH) is a pituitary glycoprotein composed of two post translationally modified subunits, which must properly assemble to be biologically active. We developed a transgenic (TG) mouse model that overexpresses the human Follicle-Stimulating hormone (FSH) -subunit under the bovine -casein promoter, displaying in females an excessive levels express in mammary gland. (omitted)

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Production of Human Keratinocyte 14 Promoter Driven EC-SOD Transgenic Mice

  • Kim, Sung-Hyun;Lee, Tae-Hoon;Kim, Kil-Soo;Lee, Eun-Ju;Kim, Myoung-Ok;Park, Jun-Hong;Cho, Kyoung-In;Jung, Boo-Kyung;Kim, Hee-Chul;Hwang, Sol-Ha;Lee, Hoon-Taek;Ryoo, Zae-Young
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2004년도 춘계학술발표대회
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    • pp.222-222
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    • 2004
  • Superoxide dismutases are key antioxidant enzymes in metabolism of reactive oxygen species. Three different isoforms of SOD exist in mammals. The extracellular SOD (EC-SOD) is the most recently discovered SOD family member. This isoform is a copper- and zinc-containing enzyme like Cu/Zn-SOD and a homotetrameric glycoprotein with a molecular weight of about 165 kDa in mouse. (omitted)

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Obtainment and Characterization of Brain Tumor Cell Using Vasopressin-SV40 T Ag Transgenic Mouse

  • Kim, Sung-Hyun;Lee, Eun-Ju;Kim, Myoung-Li;Park, Jun-Hong;Cho, Kyoungin;Jung, Boo-Kyung;Kim, Hee-Chul;Hwnag, Sol-Ha;Lee, Hoon-Taek;Ryoo, Zae-Young
    • 한국발생생물학회:학술대회논문집
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    • 한국발생생물학회 2003년도 제3회 국제심포지움 및 학술대회
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    • pp.105-105
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    • 2003
  • In previous reports, pVPSV.IGR2.1 transgenic mouse were described that brain tumor and lymphoma by reason of Vasopressin-SV40 T antigen. In this study, we produced pVPSV.IGR3.6 transgenic mouse that used pVPSV.IGR3.6 vector. Expression of transgene was vary different in transgenic mouse. We obtained 6 transgenic mouse line, moreover they had died at the age of 2-6 weeks without transmitting the transgene to their offspring, and had tumorigenesis on same location with pVPSV.IGR2.1 transgenic mouse. Only a founder mouse was investigated for expression of fusion gene. Here we extended this transgenic approach to the study of tumor progression. From the mouse, we confirmed brain tumor cell, after then cultured for investigate characterization. In this report, we demonstrate that reduction of survival rate in transgenic mouse fused vasopressin gene length, acquisition of brain tumor cell, composition with astrocyte cells and neuronal cells. Finally, cells had no change with increase of passage.

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임상병리검사학의 학문분류체계 개발을 위한 연구 (A Study on the Development of Academic Classification System for Biomedical Laboratory Science)

  • 구본경
    • 대한임상검사과학회지
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    • 제49권4호
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    • pp.477-488
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    • 2017
  • 이 연구는 임상병리검사학(또는 임상검사과학, 의학검사과학, 의생명검사과학)에 대한 체계적 인 접근을 하기 위해 임상병리검사학의 정체성과 학문분류체계를 가지고 논의하였다. 임상병리검사학은 한국 연구재단의 학술연구분야분류에 등재되어 있지 않다. 국내에서는 1963년 임상병리검사학과 최초로 신설된 이후 전국에 임상병리검사학과가 52개에 이르고 있다. 학문적 정체성에도 불구하고 제도적으로 임상병리검사학은 전문적 영역을 확보하지 못하고 있는 실정이다. 학술연구분야분류를 보면 물리치료학, 작업치료학, 치위생학은 체계적으로 분류되어 그 학문성을 인정받고 있다. 이 연구는 임상병리검사학의 새로운 학문분류체계이다. 내용 연구는 다음과 같이 요약된다. 임상병리사의 학문은 대분류 의약학, 중분류 임상병리학, 소분류 임상병리검사학에 위치한다. 세분류의 학문용어는 "혈액수혈학, 면역생화학, 미생물기생충학, 유전분자생물학, 조직세포학, 심폐신경생리학"으로 구성한다.

Produce a Novel Breast Cancer Disease Model with Test-off System

  • Park, Jun-Hong;Lee, Eun-Ju;Kim, Myoung-Ok;Kim, Sung-Hyun;Park, Jung-Ok;Cho, Kyong-In;Park, Hum-Dai;Ryoo, Zae-Young
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2002년도 춘계학술발표대회 발표논문초록집
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    • pp.93-93
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    • 2002
  • The utility of transgenic animal for studying the function of a particular gene in the breast system has been limited because transgenic typically occurs constitutively throughout development and in most tissue. So we use the inducible gene expression system. Several inducible gene expression system have been developed in vitro in recent years to overcome limitation with transgenic mice. (omitted)

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Evidance that Two Mouse Deafness Mutation, Cir and Sr, are Allelic

  • Cho, Kyung-In;Lee, Eun-Ju;Kim, Myoung-Ok;Kim, Sung-Hyun;Park, Jun-Hong;Park, Jung-Ok;Ryoo, Zae-Young
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2002년도 춘계학술발표대회 발표논문초록집
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    • pp.68-68
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    • 2002
  • Positional cloning of hereditary deafness genes is a direct approach to identify molecules and mechanisms underlying auditory function. Nowadays many deafness genes are newly identified by finding the locus for the causative genes. Mutations at many different loci in humans and mice are known to cause hearing impairment. Mouse mutants exhibiting deafness may be useful in identifying some of genes involved. (omitted)

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