Evidance that Two Mouse Deafness Mutation, Cir and Sr, are Allelic

  • Cho, Kyung-In (Laboratory of Animal Science, Kangnam St. Marys Hospital, Catholic Medical College) ;
  • Lee, Eun-Ju (Laboratory of Animal Science, Kangnam St. Marys Hospital, Catholic Medical Colleg) ;
  • Kim, Myoung-Ok (Laboratory of Animal Science, Kangnam St. Marys Hospital, Catholic Medical Colleg) ;
  • Kim, Sung-Hyun (Laboratory of Animal Science, Kangnam St. Marys Hospital, Catholic Medical Colleg) ;
  • Park, Jun-Hong (Laboratory of Animal Science, Kangnam St. Marys Hospital, Catholic Medical Colleg) ;
  • Park, Jung-Ok (Laboratory of Animal Science, Kangnam St. Marys Hospital, Catholic Medical Colleg) ;
  • Ryoo, Zae-Young (Laboratory of Animal Science, Kangnam St. Marys Hospital, Catholic Medical College)
  • Published : 2002.06.01

Abstract

Positional cloning of hereditary deafness genes is a direct approach to identify molecules and mechanisms underlying auditory function. Nowadays many deafness genes are newly identified by finding the locus for the causative genes. Mutations at many different loci in humans and mice are known to cause hearing impairment. Mouse mutants exhibiting deafness may be useful in identifying some of genes involved. (omitted)

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