Proceedings of the KSAR Conference (한국동물번식학회:학술대회논문집)
- 2004.06a
- /
- Pages.214-214
- /
- 2004
Transgene Expression of Biologically Active Human Follicle-Stimulating Hormone in Milk and Histological Analysis
- Myoung-Ok Kim (Laboratory Animal Center, Catholic Research Institutes of Medical Science, Catholic Medical College, Department of Biology, Dongguk University) ;
- Kil-Soo Kim (Department of Veterinary Medicine, College of Veterinary Medicine, Kyungpook National University) ;
- Eun-Ju Lee (Laboratory Animal Center, Catholic Research Institutes of Medical Science, Catholic Medical Colleg) ;
- Sung-Hyun Kim (Laboratory Animal Center, Catholic Research Institutes of Medical Science, Catholic Medical Colleg) ;
- Jun-Hong Park (Laboratory Animal Center, Catholic Research Institutes of Medical Science, Catholic Medical Colleg) ;
- Kyoungin-Cho (Laboratory Animal Center, Catholic Research Institutes of Medical Science, Catholic Medical Colleg) ;
- Boo-Kyung Jung (Laboratory Animal Center, Catholic Research Institutes of Medical Science, Catholic Medical Colleg) ;
- Hee-Chul Kim (Laboratory Animal Center, Catholic Research Institutes of Medical Science, Catholic Medical Colleg) ;
- Sol-ha Hwang (Laboratory Animal Center, Catholic Research Institutes of Medical Science, Catholic Medical College)
- Published : 2004.06.01
Abstract
Follicle stimulating hormone (FSH) is a pituitary glycoprotein composed of two post translationally modified subunits, which must properly assemble to be biologically active. We developed a transgenic (TG) mouse model that overexpresses the human Follicle-Stimulating hormone (FSH) -subunit under the bovine -casein promoter, displaying in females an excessive levels express in mammary gland. (omitted)