• Korean Journal of Radiology
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• v.25 no.4
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• pp.363-373
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• 2024

Objective: To develop and evaluate a deep learning model for automated segmentation and detection of bone metastasis on spinal MRI. Materials and Methods: We included whole spine MRI scans of adult patients with bone metastasis: 662 MRI series from 302 patients (63.5 ± 11.5 years; male:female, 151:151) from three study centers obtained between January 2015 and August 2021 for training and internal testing (random split into 536 and 126 series, respectively) and 49 MRI series from 20 patients (65.9 ± 11.5 years; male:female, 11:9) from another center obtained between January 2018 and August 2020 for external testing. Three sagittal MRI sequences, including non-contrast T1-weighted image (T1), contrast-enhanced T1-weighted Dixon fat-only image (FO), and contrast-enhanced fat-suppressed T1-weighted image (CE), were used. Seven models trained using the 2D and 3D U-Nets were developed with different combinations (T1, FO, CE, T1 + FO, T1 + CE, FO + CE, and T1 + FO + CE). The segmentation performance was evaluated using Dice coefficient, pixel-wise recall, and pixel-wise precision. The detection performance was analyzed using per-lesion sensitivity and a free-response receiver operating characteristic curve. The performance of the model was compared with that of five radiologists using the external test set. Results: The 2D U-Net T1 + CE model exhibited superior segmentation performance in the external test compared to the other models, with a Dice coefficient of 0.699 and pixel-wise recall of 0.653. The T1 + CE model achieved per-lesion sensitivities of 0.828 (497/600) and 0.857 (150/175) for metastases in the internal and external tests, respectively. The radiologists demonstrated a mean per-lesion sensitivity of 0.746 and a mean per-lesion positive predictive value of 0.701 in the external test. Conclusion: The deep learning models proposed for automated segmentation and detection of bone metastases on spinal MRI demonstrated high diagnostic performance.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.335-336
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• 2006

In this paper, we propose an active shape image segmentation method for three-dimensional(3-D) medical images using a generation method of the 3-D shape model. The proposed method generates the shape model using a distance transform and a tetrahedron method for landmarking. After generating the 3-D model, we extend the training and segmentation processes of 2-D active shape model(ASM) and improve the searching process. The proposed method provides comparative results to 2-D ASM, region-based or contour-based methods. Experimental results demonstrate that this algorithm is effective for a semi-automatic segmentation method of 3-D medical images.

• International Journal of Computer Science & Network Security
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• v.24 no.9
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• pp.93-96
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• 2024

The segmentation, detection, and extraction of infected tumour area from magnetic resonance (MR) images are a primary concern but a tedious and time taking task performed by radiologists or clinical experts, and their accuracy depends on their experience only. So, the use of computer aided technology becomes very necessary to overcome these limitations. In this study, to improve the performance and reduce the complexity involves in the medical image segmentation process, we have investigated many algorithm methods are available in medical imaging amongst them the Threshold technique brain tumour segmentation process gives an accurate result than other methods for MR images. The proposed method compare with the K-means clustering methods, it gives a cluster of images. The experimental results of proposed technique have been evaluated and validated for performance and quality analysis on magnetic resonance brain images, based on accuracy, process time and similarity of the segmented part. The experimental results achieved more accuracy, less running time and high resolution.

• Proceedings of the IEEK Conference
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• 2001.06e
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• pp.73-76
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• 2001

A segmentation is a prior processing for medical image analysis and 3D reconstruction. This Paper provides the method to segment 3D Visible Human color images. Firstly, the reference images that have a initial curve are segmented using Balloon and the results are propagated to the adjacent images. In the propagation processing, the result of the adjacent slice is modified by Edge-limited SRG Finally, the 3D Balloon improves the segmentation results of each 2D slice. the proposed method's performance was verified through the experiments to segment thigh muscles of Visible Human color images.

• The Journal of the Korea Contents Association
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• v.12 no.12
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• pp.63-70
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• 2012

In medical image processing field, object recognition is usually processed based on region segmentation algorithm. Region segmentation in the computing field is carried out by computerized processing of various input information such as brightness, shape, and pattern analysis. If the information mentioned does not make sense, however, many limitations could occur with region segmentation during computer processing. Therefore, this paper suggests effective region segmentation method based on R2-map information within the magnetic resonance (MR) theory. In this study, the experiment had been conducted using images including the liver region and by setting up feature points of R2-map as seed points for 2D region growing and final boundary correction to enable region segmentation even when the border line was not clear. As a result, an average area difference of 7.5%, which was higher than the accuracy of conventional exist region segmentation algorithm, was obtained.

• Journal of Biomedical Engineering Research
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• v.24 no.4
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• pp.247-257
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• 2003

This paper proposes a three-dimensional (3D) segmentation algorithm for extracting a diagnostic object from ultrasound images by using a LoG operator In the proposed algorithm, 2D cutting planes are first obtained by the equiangular revolution of a cross sectional Plane on a reference axis for a 3D volume data. In each 2D ultrasound image. a region of interest (ROI) box that is included tightly in a diagnostic object of interest is set. Inside the ROI box, a LoG operator, where the value of $\sigma$ is adaptively selected by the distance between reference points and the variance of the 2D image, extracts edges in the 2D image. In Post processing. regions of the edge image are found out by region filling, small regions in the region filled image are removed. and the contour image of the object is obtained by morphological opening finally. a 3D volume of the diagnostic object is rendered from the set of contour images obtained by post-processing. Experimental results for a tumor and gall bladder volume data show that the proposed method yields on average two times reduction in error rate over Krivanek's method when the results obtained manually are used as a reference data.

• Journal of Korea Multimedia Society
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• v.17 no.10
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• pp.1171-1181
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• 2014

In this paper, we propose improved methods which are image conversion and extraction method of watershed seed using morphological characteristic of teeth on complement image. Conventional tooth segmentation methods are occurred low detection ratio at molar region and over, overlap segmentation owing to specular reflection and morphological feature of molars. Therefore, in order to solve the problems of the conventional methods, we propose the image conversion method and improved extraction method of watershed seed. First, the image conversion method is performed using RGB, HSI space of tooth image for to extract boundary and seed of watershed efficiently. Second, watershed seed is reconstructed using morphological characteristic of teeth. Last, individual tooth segmentation is performed using proposed seed of watershed by watershed algorithm. Therefore, as a result of comparison with marker controlled watershed algorithm and the proposed method, we confirmed higher detection ratio and accuracy than marker controlled watershed algorithm.

• The KIPS Transactions:PartB
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• v.13B no.4 s.107
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• pp.401-408
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• 2006

In this paper, we propose a new class of segmentation technique for feature extraction based on the statistical and regional classification at each vertical or horizontal line of digital image data. Data is processed and clustered at each line, different from the point or space process. They are designed to segment gray-scale sectional images using a horizontal and vertical line process due to their statistical and property differences, and to extract the feature. The techniques presented here show efficient results in case of the gray level overlap and not having threshold image. Such images are also not easy to be segmented by the global or local threshold methods. Line pixels inform us the sectionable data, and can be set according to cluster quality due to the differences of histogram and statistical data. The total segmentation on line clusters can be obtained by adaptive extension onto the horizontal axis. Each processed region has its own pixel value, resulting in feature extraction. The advantage and effectiveness of the line-cluster approach are both shown theoretically and demonstrated through the region-segmental carotid artery medical image processing.

• Journal of Korea Multimedia Society
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• v.15 no.9
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• pp.1075-1085
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• 2012

In clinical research using medical images, the image segmentation is one of the most important processes. Especially, the hippocampal atrophy is helpful for the clinical Alzheimer diagnosis as a specific marker of the progress of Alzheimer. In order to measure hippocampus volume exactly, segmentation of the hippocampus is essential. However, the hippocampus has some features like relatively low contrast, low signal-to-noise ratio, discreted boundary in MRI images, and these features make it difficult to segment hippocampus. To solve this problem, firstly, We selected region of interest from an experiment image, subtracted a original image from the negative image of the original image, enhanced contrast, and applied anisotropic diffusion filtering and gaussian filtering as preprocessing. Finally, We performed an image segmentation using two level set methods. Through a variety of approaches for the validation of proposed hippocampus segmentation method, We confirmed that our proposed method improved the rate and accuracy of the segmentation. Consequently, the proposed method is suitable for segmentation of the area which has similar features with the hippocampus. We believe that our method has great potential if successfully combined with other research findings.

• The KIPS Transactions:PartA
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• v.13A no.5 s.102
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• pp.465-472
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• 2006

Recently, many suggestions have been made in image segmentation methods for extracting human organs or disease affected area from huge amounts of medical image datasets. However, images from some areas, such as brain, which have multiple structures with ambiruous structural borders, have limitations in their structural segmentation. To address this problem, clustering technique which classifies voxels into finite number of clusters is often employed. This, however, has its drawback, the influence from noise, which is caused from voxel by voxel operations. Therefore, applying image enhancing method to minimize the influence from noise and to make clearer image borders would allow more robust structural segmentation. This research proposes an efficient structural segmentation method by filtering based clustering to extract detail structures such as white matter, gray matter and cerebrospinal fluid from brain MR. First, coherence enhancing diffusion filtering is adopted to make clearer borders between structures and to reduce the noises in them. To the enhanced images from this process, fuzzy c-means clustering method was applied, conducting structural segmentation by assigning corresponding cluster index to the structure containing each voxel. The suggested structural segmentation method, in comparison with existing ones with clustering using Gaussian or general anisotropic diffusion filtering, showed enhanced accuracy which was determined by how much it agreed with the manual segmentation results. Moreover, by suggesting fine segmentation method on the border area with reproducible results and minimized manual task, it provides efficient diagnostic support for morphological abnormalities in brain.