• Journal of Radiation Protection and Research
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• 제32권1호
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• pp.27-34
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• 2007

본 논문에서는 일반인과 상대적으로 방사선피폭이 많은 핵의학 종사자들의 생체신호를 측정하여 방사선 피폭에 따른 생체신호 변화 정도를 비교 평가하고자 하였다. 핵의학과 종사자와 타부서 종사자들의 생체신호를 비교평가 하기 위하여 핵의학 종사자는 충북대학교 병원 핵의학과 종사자를 타부서 종사자는 전남대학교 병원 CT설, 일반촬영실, 의무기록실, 접수실 그리고 일반 사무실 종사자들에게 실험을 실시하였다. 실험에 쓰인 계측 장비들은 방사선량 계측을 위하여 Arrow -Tech사(社)의 poket dosimeter를 사용하였고, 생체신호인 심박수, 혈압을 측정하기 위하여 GE Medical Systems사(社)의 TONOPORT V, Heat flux, Skin temperature, Energy expenditure을 측정하기 위하여 Body Media사(社)의 Armband 인 SenseWare 2000을 사용하였다. 실험 결과 다음과 같은 결론을 얻었다. 1) 일일 장소에 따른 개인별 피폭 선량은 핵의학과가 3.05 uSv를 기록하였고, CT실, 일반촬영실, 병원 의무기록실, 병원 접수실, 일반 사무실, 교원 등이 뒤를 이었다. 핵의학과가 다른 장소(핵의학과를 제외한 나머지)에 비해 약1.4배 선량이 많았다. 2) 방사선 누적선량이 Heat flux, Skin temperature, Energy expenditure와는 별다른 관계가 없는 것을 알 수 있었다. 3) Blood pressure 에서는 Systolic blood pressure와 Diastolic blood pressure 이 핵의학과 종사자, 일반사무직 종사자, 일반인이 고르게 나타났다. 방사선선량이 상대적으로 많은 곳에서 근무하는 핵의학 종사자와 다른 직종에 종사하는 사람의 혈압을 비교해 왔을 때 변화가 없었다. 이 같은 결과로 볼 때 방사선 피폭이 상대적으로 많은 핵의학종사자들의 방사선 피폭에 따른 유해는 없다는 것을 알 수 있었다.

• Journal of Radiation Protection and Research
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• 제30권4호
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• pp.185-196
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• 2005

의료 목적으로 X선 촬영이나 CT, PET과 같은 진단방사선 피폭은 불가피하지만 선진국에서 의료 방사선이 최대의 인공 피폭원을 구성하고 있고 또 빠르게 증가하는 경향에 있음을 고려하면 의료상 피폭의 특성이나 그 결과로 인한 환자 선량 크기를 이해하는 것은 매우 중요하다. 이에 2002년도를 기준으로 단위 진료행위별 선량과 국내 의료보험 통계자료를 결합하여 방사선 진료절차별 집단선량과 1인당 유효선량 평가하였다. 절차의 유효선량 값은 NRPB 보고서, ICRP 80, MIRDOSE3.1 및 우리가 독립적으로 산출한 자료들로부터 편집하였다. 평가 결과 연간 집단선량은 진단방사선 22880man-Sv, 핵의학 4560man-Sv로서 총 27440 man-Sv로 나타났으며 따라서 인구 4770만 명을 나눈 1인당 연평균 의료상 피폭선량은 0.58mSv였다. 이 집단선량은 2002년 16기의 원전을 가동한 우리나라의 직업상피폭 70man-Sv보다 크게 많다. 특히 CT 촬영만의 집단선량도 9960man-Sv에 이름은 주목할 일이다. 이 결과는 국가의 방사선방호 정책이 의료에서 환자선량 최적화에 보다 주목해야 함을 시사한다.

• 대한방사선기술학회지:방사선기술과학
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• 제39권1호
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• pp.13-17
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• 2016

모든 의료방사선 검사는 정당성과 최적화가 확보되어야 한다. 특히 질병의 예방과 조기 진단을 목적으로 하는 건강검진에서 방사선 피폭의 최적화를 위한 모니터링은 절대적으로 필요하다. 본 연구에서는 DICOM 규격을 이용하여 건강검진센터의 의료방사선 피폭 품질관리 사례에 대해 보고하고자 한다. 적용된 시스템을 이용하여 건강검진센터의 진단참고 값을 제정하고 이를 통한 품질관리를 시행하였다. CT에서는 전체 703명에 대한 진단참고 값으로 복부검사에서 $357.9mGy{\cdot}cm$, 두부검사에서 $572.38mGy{\cdot}cm$, 심장혈관 칼슘검사에서 $55.92mGy{\cdot}cm$, 저선량 폐 검사에서 $53.98mGy{\cdot}cm$, 경추 검사에서 $284.99mGy{\cdot}cm$, 요추 검사에서 $341.85mGy{\cdot}cm$를 도출 하였으며, 흉부 X선 검사 1955건에 대해 $274.0mGy{\cdot}cm$2과 유방 촬영에서는 6.09 mGy의 진단참고 값를 도출하였다. 본 연구에서 개발된 시스템은 건강검진센터에서 수검자에 조사되는 방사선의 피폭선량을 실시간으로 모니터링하고 이를 이용한 피폭선량의 최적화와 정당화를 위한 품질관리 도구로 활용될 것이다.

• Toxicological Research
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• 제25권4호
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• pp.209-216
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• 2009

We have recently reported that the continuous exposure of rats to a concrete building environment under cool temperatures had adverse effects on general health parameters and embryo-fetal development. This study examined to compare the potential effects of concrete and wood building environments on pregnant dams and embryo-fetal development in rats. Groups of 10 mated females were exposed to polycarbonate (control), concrete, or wood cages from gestational days (GD) 0 to 20 under cool temperatures $(11.9\sim12.3^{\circ}C)$. All the females underwent a caesarean section on GD 20, and their fetuses were examined for any morphological abnormalities. The temperatures in the cages were similar in all groups but the relative humidity in the concrete and wood groups were higher than in the control group. The concentration of volatile organic compounds in the wood group was higher than in the control group. In the concrete group, maternal effects manifested as an increase in the incidence of clinical signs, a lower body weight, and a decrease in the thymus and ovary weights. Developmental effects included increased post-implantation loss and decreased litter size. Infrared thermal analysis showed that the skin temperature of the rats in the concrete group was lower than that in the control group. In contrast, there were no exposure-related adverse effects on the maternal and developmental parameters in the wood group. Overall, the exposure of pregnant rats to a concrete building environment under cool temperatures has adverse effects on the clinical signs, body weight, skin temperature, organ weight, and embryo-fetal development. On the other hand, exposure to a wood building environment does not have any adverse effects in rats.

• Journal of Korean Biological Nursing Science
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• 제11권2호
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• pp.120-127
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• 2009

Purpose: The study aimed at monitoring the immune status of health care workers (HCWs) of a tertiary hospital after accidental exposure to Hepatitis B virus (HBV). Methods: Between January 2004 and December 2006, 353 cases of exposure to Hepatitis B virus were reported. The HBV-exposed HCWs were required to undergo follow-up serum tests to analyze their immune status one year after the exposure. The obtained data were then analyzed to determine the incidence of exposure and of sero-conversion. Results: In this hospital, an average of 9.8 cases of Hepatitis B exposure among HCWs was reported in a month. Follow-up tests conducted after exposure revealed that 90.4% of the HBV-exposed HCWs were positive for Hepatitis B antibody and 66.9% of the HBV-exposed HCWs were reported to have antibody levels exceeding 10 mIU/mL. Results of serum tests for the HBV antigen conducted one year after exposure were negative for all the exposed HCWs. Conclusion: Among the 79.6% of the HCWs who underwent serum tests one year after exposure the HBV sero-conversion rate was 0.0%. However, a further investigation in the form of long-term and multi-center studies is required to confirm this result. Furthermore, an active system should be established to ensure that all exposed HCWs undergo follow-up serum tests.

• 한국학교ㆍ지역보건교육학회지
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• 제8권1호
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• pp.69-77
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• 2007

Background & Objectives: International radiation protection committee recognized the importance of radiation protection from medical practices because the exposure to the radiation in medical practice is higher than any other exposure. The factors on knowledge, attitude and practice of radiation safety of the medical workers engaged in radiation were analyzed in order to improve radiation safety technology. Method: Questionnaires were used for 1200 radiation workers in medical institution from July 23 through September 4 and collected for analysis. Results: Different level of safety measures were practiced by age, marital status, career, and medical facility. The difference was statistically significant. Higher levels of safety measures were practiced in the age group of 50s and married persons. The workers who have more than 20 years experience have higher level of safety measures. The workers of health centers have higher level of safety measures to compare with other workers. The factors which give more concerns on safety practice were self efficacy, practice and knowledge in order. Conclusion: Safety conscious operators should get additional education program to maintain higher level of safety. The operators who do not have much safety concern should be intensive training program for self efficacy and safety.

• Asian Pacific Journal of Cancer Prevention
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• 제15권19호
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• pp.8171-8175
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• 2014

Background: To study the radioprotective effects of flavonoids from Rosa roxburghii Tratt (FRT). Materials and Methods: The radioprotective effects of FRT were investigated by examining cell viability, 30-day survival of mice and the number of colony-forming units in spleen (CFU-S) after total-body 60Co irradiation. Results: The survival rates of irradiated cells gradually increased with increasing concentrations of FRT. The survival rate was the highest at 87% with a concentration of $30{\mu}g/mL$. Pretreatment with FRT was needed to realize its radioprotective activity in mice at the dose of 60 mg/kg. With the increasing doses of 30 mg/kg, 60 mg/kg and 120 mg/kg, the numbers of CFU-S increased, and were significantly different compared with the control group. Conclusions: Pretreatment with FRT prior to irradiation resulted in significantly higher cell survival at 24 h after 5 Gy radiation, increased 30-day survival in mice after exposure to a potentially lethal dose of 8 Gy, and resulted in a higher number of CFU-S in mice after exposure to a dose of 6 Gy. These results collectively indicate that FRT is an effective radioprotective agent.

• 미생물학회지
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• 제12권2호
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• pp.67-76
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• 1974

This experiment was carried out to identify and to compare the radiosensitivities of bacteriz isolated from the sources of different radiation exposure histories. Among 10 strains isolated in this investigation, 4 strains of bacteria, Bacillus firmus, Bacillus brevis, Baciilus subtilis and Bacillus sphaericus were isolated from high and low radioactive sites simulaneously. Bacterial strains isolated from radioactive sources such as reactor and isotope production rooms were more resistant to irradiation than the microganisms from medical products and laboratories, however, there was no significance in radiosensitivity in the same species of bacteriz, even if they were isolated from different radiation exposure histories.

• 핵의학기술
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• 제21권2호
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• pp.86-93
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• 2017

Purpose In this study, radiation workers who work in nuclear medicine department were analyzed to find the cause of differences of radiation exposure from General Characteristic, Knowledge, Recognition and Conduct, especially females working on nuclear medicine radiation, in order to pave the way for positive defense against radiation exposure. Materials and Methods The subjects were 106 radiation workers who were divided into two groups of sixty-four males and forty-two females answered questions about their General Characteristic, Knowledge, Recognition, Conduct, and radiation exposure dose which was measured by TLD (Thermo Luminescence Dosimeter). Results The results of the analysis revealed that as the higher score of knowledge and conduct was shown, the radiation exposure decreased in female groups, and as the higher score of conduct was shown, the radiation exposure decreased in male groups. In the correlation analysis of female groups, the non-experienced in pregnancy showed decreasing amount of radiation exposure as the score of knowledge and conduct was higher and the experienced in pregnancy showed decreasing amount of radiation exposure as the score of recognition and conduct was higher. In the regression analysis on related factors of radiation exposure dose of nuclear medicine radiation workers, the gender caused the meaningful result and the amount of radiation exposure of female groups compared to male groups. In the regression analysis on related factors of radiation exposure dose of female groups, the factor of conduct showed a meaningful result and the amount of radiation exposure of the experienced in pregnancy was lower compared to the non-experienced. Conclusion The conclusion of this study revealed that radiation exposure of female groups was lower than that of male groups. Therefore, male groups need to more actively defend themselves against radiation exposure. Among the female groups, the experienced in pregnancy who have an active defense tendency showed a lower radiation exposure. Thus, those who have never been pregnant need to have a more active defensive conduct for the future possibility of pregnancy.

• 대한생식의학회:학술대회논문집
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• 대한불임학회 1995년도 추계 학술대회 및 정기총회
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• pp.65-65
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• 1995