• 제목/요약/키워드: Medical Complications

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편친 이염색체성 엔젤만 증후군(Angelman syndrome) 환자의 치과치료 (DENTAL TREATMENT IN A PATIENT WITH ANGELMAN SYNDROME DUE TO UNIPARENTAL DISOMY)

  • 박성희;신터전;현홍근;김영재;김정욱;이상훈;김종철;장기택
    • 대한장애인치과학회지
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    • 제12권1호
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    • pp.11-15
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    • 2016
  • 저자는 엔젤만 증후군 중 그 발생 기전이 2% 이하인 편친 이염색체성 엔젤만 증후군 증례를 안전하고 효과적으로 치료하였기에 이를 보고하는 바이다. 환자는 근육간대경련발작(myoclonic seizure)의 병력으로, 조절을 위해 항경련제(Valproate)를 복용중이었고, 전반적인 발육 장애와 지적 장애, 언어 장애를 나타내고 있었다. 구내 소견으로는 치간 이개, 하악골 전돌, 거대설과 연하 장애가 관찰되었으며, 잦은 불수의적 운동 때문에 구강 위생 상태는 매우 불량 하였다. 치료 범위가 광범위하고, 환자의 협조도를 얻을 수 없었으며, GABA 수용체의 기능장애로 인해 진정 약물을 이용한 행동 조절은 효과적이지 않을 것으로 판단하여 전신마취 하에서 치과치료를 시행하였고, 성공적으로 치과치료가 가능했다. 엔젤만 증후군 환자들도 정기적인 치과 방문을 통한 구강 위생 교육, 전문가 치면 세마, 불소 도포가 이루어진다면 적절한 구강 건강을 유지할 수 있으며, 주기적인 치과 방문을 통해 환자가 치과 진료에 적응 한 뒤에는 간단한 치료도 가능하다.

CATCH22 syndrome 환아의 전신마취 하 치아우식 치료: 증례보고 (DENTAL TREATMENT OF A PATIENT WITH CATCH22 SYNDROME UNDER GENERAL ANESTHESIA: A CASE REPORT)

  • 김민진;송지수;신터전;김영재;김정욱;장기택;이상훈;현홍근
    • 대한장애인치과학회지
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    • 제14권1호
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    • pp.36-40
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    • 2018
  • CATCH 22 증후군(CATCH 22 Syndrome)은 선천성 심장기형, 비정상적인 안모, 흉선 형성부전, 구개열, 저칼슘혈증을 특징으로 하나 임상양상은 다양하게 나타난다. 본 증례는 치과 검진에 비협조적이고 다수의 치아 우식을 보이는 4세 5개월의 CATCH 22 증후군 환자를 전신마취 하에 효과적으로 치료하였기에 이를 보고하는 바이다. CATCH 22 증후군 환아는 선천적 심장기형을 동반하는 경우가 많아 의과적 자문 하에 치과 치료를 시행해야 한다. 간단한 치료의 경우 의과적 자문 하에 진정법 시행을 고려해 볼 수 있으나 불안정한 생징후를 보일 수 있어 보다 면밀한 모니터링을 요한다. CATCH22 환아의 전신상태에 대한 충분한 이해 및 술전 평가를 바탕으로 한 주의깊게 시행된 전신마취 술식은 다발성 치아우식의 치료에 있어서 보다 안전하고 효과적인 방법이 될 수 있을 것으로 사료된다.

Lennox-Gastaut syndrome 환아의 전신마취 하 치아우식 치료: 증례보고 (DENTAL TREATMENT OF A PATIENT WITH LENNOX-GASTAUT SYNDROME UNDER GENERAL ANESTHESIA: CASE REPORT)

  • 서희원;송지수;신터전;현홍근;김영재;김정욱;이상훈;장기택
    • 대한장애인치과학회지
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    • 제14권1호
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    • pp.22-25
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    • 2018
  • 레녹스-가스토 증후군은 다양한 종류의 발작이 복합적으로 나타나는 질환으로 치료가 어렵고, 예후가 좋지 않다. 복용 중인 약물에 의해 구강 내 치은 부종 등의 증상이 나타날 수 있고, 치태 축적에 의한 우식의 위험성이 높기 때문에 구강 위생 관리가 중요하다. 치과치료를 필요로 하는 경우, 발작의 정도, 복용 중인 약물 및 환아의 협조도를 고려해 치료계획을 세워야 한다. 발작의 정도가 심하고, 협조도가 좋지 않은 경우, 전신마취를 계획할 수 있으며, 이 때 의과적 자문을 반드시 고려해야 한다.

Clinical analysis and review of literature on pilomatrixoma in pediatric patients

  • Hu, Ju Long;Yoo, Hyokyung;Kwon, Sung Tack;Kim, Sukwha;Chung, Jee Hyeok;Kim, Hyeonwoo;Kim, Jinhyun;Yu, Na Hee;Kim, Byung Jun
    • 대한두개안면성형외과학회지
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    • 제21권5호
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    • pp.288-293
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    • 2020
  • Background: Pilomatrixoma is a benign tumor that originates from the hair follicle matrix. It usually presents as a hard, slow growing, solitary mass that can be easily misdiagnosed as other skin masses. The aim of this study was to clinically analyze a case series of pilomatrixoma in pediatric patients from Korea. Methods: A total of 165 pediatric patients from 2011 to 2018 with a histological diagnosis of pilomatrixoma were included. A retrospective review was performed using the electronic medical records, including patient demographics, number and location of the mass, clinical and imaging presentation, and postoperative outcomes. Results: There were 61 male and 104 female patients with 152 solitary and 13 multiple pilomatrixomas. Among solitary pilomatrixomas, the lesion commonly occurred in the head and neck (84.2%), followed by upper limbs (11.2%), lower limbs (3.3%), and trunk (1.3%). The pilomatrixoma lesion presented as the following types based on our clinical classification: mass (56.02%), pigmentation (25.31%), mixed (12.65%), ulceration (4.82%), and keloid-like (1.2%). Ultrasonography showed a high positive predictive value (95.56%). There were no specific complications observed except for two cases of recurrence. Conclusion: Pilomatrixoma has various clinical feature presentations and commonly occurs in the head and neck. Ultrasonography is a helpful diagnostic tool. Surgical removal of the lesion is the main treatment method with a low recurrence rate.

유치도뇨관 삽입 가정간호대상자 가족의 유치도뇨관 관리에 관한 지식, 교육요구 및 교육경험 (A Study on Knowledge, Educational Needs and Educational Experience for Indwelling Catheter Management in the Families of Home Care Clients)

  • 김정순;이상주;강인순
    • 가정∙방문간호학회지
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    • 제12권1권
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    • pp.92-116
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    • 2005
  • Purpose: This study was a predicative survey to provide home care clients with indwelling urinary catheters for furnishing basic educational material to their families by analyzing the family members' knowledge, educational needs and educational experience about indwelling catheter management. Method : The subjects consisted of 108 family members who cared for home care clients with indwelling catheters. Data were collected by home care nurses in nine hospitals in Pusan, who directly interviewed with them through questionnaires from Sep. 6th to 30th in 2004. The questionnaires for data collection were developed through pre-survey and reference review. The collected data was analyzed by using frequency, percentile, mean, variation, t-test, ANOVA on SPSS 10.1 package. Results : There were characters of home care clients with indwelling catheters: women(67.6%) were more than men; the average age of them was $69.60{\pm}14.99$ years old; neurogenic and cerebrovascular diseases(80.0%) were the most common disease group; 81.5% of them were totally dependent on others in terms of level of activity. Home care clients' families had these characters: women(76.9%) were more than men; the average age was $54.5{\pm}13.70$ years old; 46.3% of them were parents or sons or daughters in terms of relation with patient; tl1e average care period was $39.8{pm}34.20$ months. Level of knowledge about indwelling catheter management of the family members were 69.8% and its mean were $20.24{\pm}4.53$. Educational needs were 90.9% and its mean were $14.55{\pm}3.56$. Educational experience were 53.3% and its mean were $8.53{\pm}4.30$. 'Complications in using an indwelling catheter', 'Symptoms to call for a home care nurse' and 'Method to attach an indwelling catheter' were high ranked in both educational needs and educational experience. 'Anatomy of urinary tract', 'Functions of urinary tract' and 'Catheter placement' were low ranked in both educational needs and educational experience Level of knowledge about indwelling catheter management of the families showed a significant difference according to their age(F=5.35, p=0.01). Educational needs showed a significant difference according to care period(F=3.06, p=0.04). Conclusion: the family members' level of knowledge and educational experience about indwelling catheter management and their educational were not sufficient while their educational needs were high. In other words although the family members were acknowledged education needs, but the care for the patients with indwelling catheter weren't performed well because of their lack of related knowledge. Therefore systematic educational programs about indwelling catheter management for home care clients and their families should be made on the base of this study.

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수면과 관련된 호흡장애 (Sleep-Related Respiratory Disturbances)

  • 문화식
    • 수면정신생리
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    • 제2권1호
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    • pp.55-64
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    • 1995
  • 수면중에는 여러 가지 호흡생리의 변화가 나타나는데, 호흡의 수의적 조절은 경미하고 대부분 대사성조절에 의해 호흡이 유지되며, 탄산가스와 산소변화에 의한 화학자극 및 호흡기계통의 기계적 자극에 대한 환기반응이 감소하고, 늑간근 및 상기도근육들과 같은 보조호홉근의 기능이 억제되며, 체위변동 즉 누운 자세에서는 여러 가지 호흡기능의 변화가 온다. 이러한 호흡생리의 변화로 정상인에서도 수면 중에는 경미한 환기장애(저환기)를 보일 수 있으며, 수면 무호흡이 있는 경우에는 환기장애가 더욱 현저하다. 환기장애 즉 만성 폐포저환기를 동반하는 질환은 심폐질환 이외에도 여러 가지가 있으며 수면 무호흡 증후군은 환기장애를 일으키는 중요한 원인중의 하나이다. 만성 폐포저환기를 보이는 환자는 원인질환에 관계없이 수면중에 환기장애가 더욱 심해지며 특히 수면 무호흡이 빈번하게 동반되는 경우에는 중증의 임상경과를 보인다. 폐쇄성 수면 무호흡증후군 환자는 수면중에 반복되는 저산소증과 각성반응으로 수면장애증상 이외에도 전신 고혈압과 심부정맥이 흔히 동반되며, 주간에도 저산소증을 보이는 심폐질환자에서 수변 무호흡증후군이 동반되는 경우 폐동맥고혈압과 폐성심이 올 수 있다. 이러한 심폐혈관계 합병증은 수면 무호흡증후군 환자의 장기사망율을 높이는 중요한 원인이 되며, 중증 환자의 경우 수면중에 급사할 수도 있다. 폐쇄성 수면 무호흡증후군 환자의 심폐혈관계 합병증과 장기사망율을 감소시키기 위해서는 적절한 치료법이 요구되며, 환기장애(만성 폐포저환기)의 다른 원인질환이 함께 있는 경우에는 수면 무호흡의 치료와 병행하여 이들 질환의 치료를 동시에 실시하여야 한다.

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Urokinase와 동의학적요법(東醫學的療法)으로 동시치료(同時治療)한 허혈성뇌졸중환자(虛血性腦卒中患者) 56례(例)에 대(對)한 임상적(臨床的) 연구(硏究) (Clinical Studies on 56 Cases of Having Treated patients suffering from Ischemic Stroke through both Urokinase and Therapeutics of Oriental Medicine)

  • 김인섭
    • 대한한의학회지
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    • 제15권2호
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    • pp.46-91
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    • 1994
  • l. Backgrounds of Studies Cerebrovascular accident. one of the three major causes of death among audults with cardiopathy and malignancy, has been on the increase in korea while it is on the decrease in European countries and Japan. Types of stroke undergo changes caused by prolongment of life expectancy. and social and economic variety. More patients of ischemic stroke show a tendency to increase now than those of hemorrhagic stroke in the past. Many clinical studies on medical cerebrovascular and oriental stroke of paralysis have been published. but few clinical studies on therapeutics of integrated oriental and western medicine are to be found. So I have made an attempt to study clinical observations and therapeutic responses of ischemic stroke under integrated oriental and western medicine. 2.Methods. Among the patients admitted into the clinic of Joong-Poong, Woo-Suk University Hospital from May 1. 1993 until April 30. 1994 those 56 patients who were diagnosed as ischemic stroke on Computed Tomography(CT) and showed no dubious symptom after examination of coagulation and bleeding time were classified into the following six steps and treated: l)diagnosis 2)emergency treatment 3)basic treatment 4)treatment of risk and provoking factors. and preceeding disease 5)complications and conservative therapy 6)rehabilitation. For a period of basic treatment both herb medication and urokinase therapy were applied at the same time. Intravenous injection has been given at a unit of 300.000 dosage a day as urokinase therapy during basic treatment. If they showed any dubious symptom in glucose tolerance test. fructose 500ml and urokinase 300.000 dosage were mixed and injected. In case of no symptom 5% DW 500ml was mixed with urokinase 300.000 unit. and injected at a speed of 15gtt per minute. 3. Results and Conclusions 1) The level of ambulation has been improved from 42.9% when admitted to 73.2% when discharged in the degree of recovery. The level of severe function disorder has been remarkably decreased from 55.4% when admitted to 19.6% when discharged. 2) The treatment effect on the basis of therapeutic response of clinical and subjective symptom shows as follows: 7.1% Excellent. 35.7% Good. 37.5% Effective. 10.7% Stationary. and 8.9% Aggravated. The total recovery above effective shows 80.3%. Judging from the above results I think it proper to develop the model of better preventing and treating ischemic stroke through effective therapeutic and clinical studies of integrated oriental and western medicine.

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Outcomes of Local Excision for Early Rectal Cancer: a 6-year Experience from the Largest University Hospital in Thailand

  • Lohsiriwat, Varut;Anubhonganant, Worabhong;Prapasrivorakul, Siriluck;Iramaneerat, Cherdsak;Riansuwan, Woramin;Boonnuch, Wiroon;Lohsiriwat, Darin
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권9호
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    • pp.5141-5144
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    • 2013
  • Background: This study aimed to determine clinical outcomes of local excision for early rectal cancer from a University Hospital in Thailand. Materials and Methods: We performed a retrospective review of 22 consecutive patients undergoing local excision for early rectal cancer (clinical and radiological T1/T2) from 2005-2010 at the Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok. Data were collected from patients' medical records, including demographic and clinical characteristics, pathological report and surgical outcomes. Results: This study included 10 males and 12 females, with average age of 68 years. Nineteen patients (86%) underwent transanal excision and the others had trans-sacral excision. Median operative time was 45 minutes. Postoperative complications occurred in 2 patients (9%); 1 fecal fistula and 1 wound infection following trans-sacral excision. There was no 30-day postoperative mortality. Median hospital stay was 5 days. Pathological reports revealed T1 lesion in 12 cases (55%), T2 lesion in 8 cases (36%) and T3 lesion in 2 cases (9%). Eight patients received additional treatment; one re-do transanal excision, two proctectomies, and five adjuvant chemoradiation. During the median follow-up period of 25 months, local recurrence was detected in 4 patients (18%); two cases of T2 lesions with close or positive margins, and two cases of T3 lesions. Three patients with local recurrence underwent salvage abdominoperineal resection. No local recurrence was found in T1/T2 lesions with free surgical margins. Conclusions: Local excision is a feasible and acceptable alternative to radical resection only in early rectal cancer with free resection margins and favorable histopathology.

심도자술후 발생한 대퇴동맥 혈전증 환아에서 동맥내 Urokinase 국소 주입요법의 효과 (Intraarterial Catheter-directed Urokinase Infusion for Femoral Artery Thrombosis after Cardiac Catheterization in Infants and Children)

  • 이형두
    • Clinical and Experimental Pediatrics
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    • 제45권11호
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    • pp.1397-1402
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    • 2002
  • 목 적 : 대퇴동맥 혈전증은 하지 절단같은 극단적인 재앙뿐만 아니라 하지의 성장 장애를 초래할 수 있는 심도자술의 심각한 합병증이지만, 소아에서 이에 대한 표준적 치료법은 아직 정립되지 못한 상태이다. 저자는 심도자술후 발생한 대퇴동맥 혈전증에서 urokinase의 동맥내 국소 주입요법의 유용성을 검토하고자 본 연구를 시행하였다. 방 법 : 1994년 1월부터 2002년 8월까지 심도자술 후 발생한 대퇴동맥 혈전증으로 동아대학교병원 소아과에서 동맥내 urokinase 국소 주입법을 이용해 혈전용해술을 받은 9명, 12례를 대상으로 하여, 병력지와 혈관조영 소견을 후향적으로 분석하였다. 결 과 : 1) 대퇴동맥을 이용한 심도자술이 행해진 391례 중 전신적 헤파린 또는 urokinase에 반응을 보이지 않았던 대퇴동맥 혈전증의 발생빈도는 2.8퍼센트였다. 2) 대상 환아들의 연령은 기하평균 5.8개월(1-71개월)이었고 체중은 $8.5{\pm}4.6kg$(3.5-20.5 kg)였다. 3) Urokinase는 1,000-4,400 unit/kg/hr로 $50.6{\pm}29.2$시간(18-110시간)에 걸쳐 주입하였는데, 치료중 2례에서 환측의 천자부위로 출혈이 있었으며, 한명은 수혈이 필요했다. 심도자술후 4일 이내에 치료를 시작했던 환아들은 모두 혈전의 완전 소실을 보였다. 혈전 형성후 각각 12일과 19일째 치료를 시작했던 2례는 호전되지 않아 풍선 혈관성형술을 실시하였는데 부분적으로 도움이 되었다. 결 론: 심도자술후 발생한 대퇴동맥 혈전증에서, 전신적 혈전용해제 투여로 회복되지 않으면, 반대측 대퇴동맥을 통한 국소적 동맥내 혈전용해제 투여를 조기에 시행하는 것이 효과적이다.

난치성 당뇨 족부 궤양에 대한 임상적 고찰: 치료에 영향을 미치는 인자 분석 (Clinical Analysis of Intractable Diabetic Foot Ulcers: Accessing Risk Factors)

  • 박세진;이승희;박헌용;김장환;신헌규;김유진;최재열
    • 대한족부족관절학회지
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    • 제15권4호
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    • pp.232-239
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    • 2011
  • Purpose: Diabetic foot ulcer is one of the most important diabetic complications because it increases the risk of amputations. Moreover, it lowers the quality of patients' life and increases the social medical expenses. Authors analyzed risk factors of intractable diabetic foot ulcer using retrospective study. Materials and Methods: From January 2007 to December 2010, 40 patients who could not achieve complete healing despite more than 12 weeks of proper management among who had been diagnosed and treated as diabetic foot ulcer at our hospital were included and evaluated retrospectively. We compared the risk factors between two groups who were finally treated by amputation and non-amputation. Results: The sample was composed of 31 male patients (77.5%) and 9 female patients (22.5%). Comorbidity including hypertension and hyperlipidemia were 77.5% and 80% each. By Wagner classification, 30 patients (80%) had ulcerative lesion over the grade 3. From bacteriology results, 29 patients (72.5%) had polybacteria infection. 35 patients (87.5%) had neuropathy and 26 patients (65%) had vascular stenosis at least one level. The mean initial ankle-brachial index and toe-brachial index were 0.982 and 0.439. In comparison between amputation group and non-amputation group, ulcer severity, number of stenotic vessel and initial ankle-brachial index/toe-brachial index had statistical significance. Conclusion: The most commonly risk factor of intractable diabetic foot ulcer was peripheral neuropathy reaching 87.5% of cases. In comparison with non-amputation group, ulcer severity according to Wagner classification, number of stenotic vessel and initial ankle-brachial index/toe-brachial index were demonstrated as a risk factor of amputation in intractable diabetic foot ulcer.