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Clinical analysis and review of literature on pilomatrixoma in pediatric patients

  • Hu, Ju Long (Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Yoo, Hyokyung (Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Kwon, Sung Tack (Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Kim, Sukwha (Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Chung, Jee Hyeok (Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Kim, Hyeonwoo (Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Kim, Jinhyun (Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Yu, Na Hee (Biomedical Research Institute, Department of Plastic and Reconstructive Surgery, Seoul National University Hospital) ;
  • Kim, Byung Jun (Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine)
  • Received : 2020.09.15
  • Accepted : 2020.10.20
  • Published : 2020.10.20

Abstract

Background: Pilomatrixoma is a benign tumor that originates from the hair follicle matrix. It usually presents as a hard, slow growing, solitary mass that can be easily misdiagnosed as other skin masses. The aim of this study was to clinically analyze a case series of pilomatrixoma in pediatric patients from Korea. Methods: A total of 165 pediatric patients from 2011 to 2018 with a histological diagnosis of pilomatrixoma were included. A retrospective review was performed using the electronic medical records, including patient demographics, number and location of the mass, clinical and imaging presentation, and postoperative outcomes. Results: There were 61 male and 104 female patients with 152 solitary and 13 multiple pilomatrixomas. Among solitary pilomatrixomas, the lesion commonly occurred in the head and neck (84.2%), followed by upper limbs (11.2%), lower limbs (3.3%), and trunk (1.3%). The pilomatrixoma lesion presented as the following types based on our clinical classification: mass (56.02%), pigmentation (25.31%), mixed (12.65%), ulceration (4.82%), and keloid-like (1.2%). Ultrasonography showed a high positive predictive value (95.56%). There were no specific complications observed except for two cases of recurrence. Conclusion: Pilomatrixoma has various clinical feature presentations and commonly occurs in the head and neck. Ultrasonography is a helpful diagnostic tool. Surgical removal of the lesion is the main treatment method with a low recurrence rate.

Keywords

References

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