• Title/Summary/Keyword: Medical 3D printing

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Effects and Application Cases of Injection Molds by using DED type Additive Manufacturing Process (DED방식의 적층가공을 통한 금형으로의 응용사례 및 효과)

  • Kim, Woosung;Hong, Myungpyo;Kim, Yanggon;Suh, Chang Hee;Lee, Jongwon;Lee, Sunghee;Sung, Ji Hyun
    • Journal of Welding and Joining
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    • v.32 no.4
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    • pp.10-14
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    • 2014
  • Laser aided Direct Metal Tooling(DMT) process is a kind of Additive Manufacturing processes (or 3D-Printing processes), which is developed for using various commercial steel powders such as P20, P21, SUS420, H13, D2 and other non-ferrous metal powders, aluminum alloys, titanium alloys, copper alloys and so on. The DMT process is a versatile process which can be applied to various fields like the mold industry, the medical industry, and the defense industry. Among of them, the application of DMT process to the mold industry is one of the most attractive and practical applications since the conformal cooling channel core of injection molds can be fabricated at the slightly expensive cost by using the hybrid fabrication method of DMT technology compared to the part fabricated with the machining technology. The main objectives of this study are to provide various characteristics of the parts made by DMT process compared to the same parts machined from bulk materials and prove the performance of the injection mold equipped with the conformal cooling channel core which is fabricated by the hybrid method of DMT process.

Maxillary protraction using customized mini-plates for anchorage in an adolescent girl with skeletal Class III malocclusion

  • Liang, Shuran;Xie, Xianju;Wang, Fan;Chang, Qiao;Wang, Hongmei;Bai, Yuxing
    • The korean journal of orthodontics
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    • v.50 no.5
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    • pp.346-355
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    • 2020
  • The treatment of skeletal Class III malocclusion in adolescents is challenging. Maxillary protraction, particularly that using bone anchorage, has been proven to be an effective method for the stimulation of maxillary growth. However, the conventional procedure, which involves the surgical implantation of mini-plates, is traumatic and associated with a high risk. Three-dimensional (3D) digital technology offers the possibility of individualized treatment. Customized mini-plates can be designed according to the shape of the maxillary surface and the positions of the roots on cone-beam computed tomography scans; this reduces both the surgical risk and patient trauma. Here we report a case involving a 12-year-old adolescent girl with skeletal Class III malocclusion and midface deficiency that was treated in two phases. In phase 1, rapid maxillary expansion and protraction were performed using 3D-printed mini-plates for anchorage. The mini-plates exhibited better adaptation to the bone contour, and titanium screw implantation was safer because of the customized design. The orthopedic force applied to each mini-plate was approximately 400-500 g, and the plates remained stable during the maxillary protraction process, which exhibited efficacious orthopedic effects and significantly improved the facial profile and esthetics. In phase 2, fixed appliances were used for alignment and leveling of the maxillary and mandibular dentitions. The complete two-phase treatment lasted for 24 months. After 48 months of retention, the treatment outcomes remained stable.

Analysis of Chung-Buk Regional Industry Trends -Focused on Machinery Part Industry and Medial Instrument Industry (충북지역 특화산업 현황 분석 -기계부품(자동차), 의료기기산업을 중심으로)

  • Lee, Hyoung-wook;Seo, JunHyeok;Park, Sung-jun;Bae, Sungmin
    • Journal of Institute of Convergence Technology
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    • v.6 no.2
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    • pp.41-46
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    • 2016
  • Based on Regional Industry Development Plan in 2014, machinery part industry and medical instrument industry has been designated as core industries of Chung-buk area. Machinery part industry plays an important role in economic growth of chung-buk area and it has been faced with signigicant changes - such as SMART factory and IoT(Internet of things). Also, medical instrument industry with 3D printing technology grows rapidly in Chung-buk area. It is believed that medical instrument could be next cash-cow items for Chung-buk area. In this paper, we survey, analyze and summarize the current machinery part industry and medical instrument industry focused on Chunk-buk Area.

A Study on the Usefulness of Copper Filter in Single X-ray Whole Spine Lateral using 3D Printer (단일조사 whole spine Lateral 검사에서 3D 프린터로 제작한 구리 필터 유용성 연구)

  • Kwon, Kyung-Tae;Yoon, Dayeon;Shin, Rae-Un;Han, Bong-Ju;Yoon, Myeong-Seong
    • Journal of the Korean Society of Radiology
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    • v.14 no.7
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    • pp.899-906
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    • 2020
  • The WSS lateral examination is important for diagnosing spinal disorders. Recently, long-length detectors for large-area diagnose have been popularized to effectively reduce the exposure dose and examination time. It can be applied very efficiently to examinations of patients with high risk of falls, children, and adolescents. However, since the image is acquired through a single irradiation, the volume of cervical vertebra is relatively smaller than the lumbar due to the geometrical anatomy of the spine. Therefore, this study intends to fabricate an additional filter using 3D printing technology and copper filament to obtain uniform image quality in the WSS lateral examination and to analyze the results. 3D printing technology is able to easily print a desired shape, so it is widely used in the entire industrial field, and recently, a copper filament has been developed to confirm the possibility as an additional filter. In the WSS lateral examination, CNR and SNR were excellently measured when the additional filter was applied, confirming the possibility of using the additional filter.

Comparative Study of Sterilization by Gamma-ray and Electron-Beam (감마선, 전자선에 의한 멸균 비교분석)

  • Jeong, Kyeonghwan;Park, Changhee
    • Journal of the Korean Society of Radiology
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    • v.14 no.5
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    • pp.537-543
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    • 2020
  • The elderly population in the modern society is growing rapidly due to advance medical technology and minimally invasive surgery. Therefore, as the tendency to use medical device is increasing, pathogenic infection is a concern. Therefore, the first aim of modern medicine is infection prevention in medical place. Recently, patient implants are increasing using 3D printing. Hydroxyapatite is used as a representative material. And, there haven't had currently absorbed dose standard for sterilization of hydroxyapatite discs. Escherichia coli and Streptococcus mutans contaminated on the surface of hydroxyapatite discs were irradiated at each absorbed dose of 0, 0.5, 1.0, 3.0, 5.0 kGy using Gamma-ray of cobalt and Electron-beam of linear accelerator. Then, the number of bacteria was measured in the sample by the decimal dilution method. After sterilization, a non-parametric testing method was performed to compare the survival of Escherichia coli and Streptococcus mutans. As a result, Escherichia coli was sterilized at 1 kGy or more and Streptococcus mutans at 3 kGy or more on absorbed dose. It is considered possible to perform sterilization at a lower value than the recommended absorbed dose of radiation sterilization.

Development of the Upper Wear Fixation Device for Chest AP X-ray Imaging on the Emergency Stretcher Bed (응급실 침대 위 흉부전후방향 엑스선 검사를 위한 상의고정장치 개발)

  • Lim, Woo-Taek;Hong, Dong-Hee
    • Journal of radiological science and technology
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    • v.45 no.3
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    • pp.205-211
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    • 2022
  • This study aimed to provide basic data for 3D printing in the medical health field by developing upper wear fixation device (UWFD), an auxiliary device for shortening chest AP examination time on emergency room beds and non-contact with patients. The standard of hooks was modeled according to the bed frame using the Autodesk Fusion 360. It was printed with Form2 (Formlabs, Somerville, MA, USA), as SLA (stereo lithography apparatus) method, and was washed and hardened using Form Wash and Form Cure. The completed UWFD conducted an online survey on 4 items of stability, convenience, availability, preference and general characteristics. The total stability average was 3.93±0.80, the total convenience average was 3.93±0.68, the total availability average was 4.01±0.89, and the total preference average was 3.80±1.08. This study was significant in suggesting improvements in the general X-ray examination process in the emergency room by designing and making aids to easily fixing the patient's top to the frame of the emergency bed while meeting promptness and non-contact with the patient.

Development and Evaluation of Hyaluronic Acid-Based Hybrid Bio-Ink for Tissue Regeneration

  • Lee, Jaeyeon;Lee, Se-Hwan;Kim, Byung Soo;Cho, Young-Sam;Park, Yongdoo
    • Tissue Engineering and Regenerative Medicine
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    • v.15 no.6
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    • pp.761-769
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    • 2018
  • BACKGROUND: Bioprinting has recently appeared as a powerful tool for building complex tissue and organ structures. However, the application of bioprinting to regenerative medicine has limitations, due to the restricted choices of bio-ink for cytocompatible cell encapsulation and the integrity of the fabricated structures. METHODS: In this study, we developed hybrid bio-inks based on acrylated hyaluronic acid (HA) for immobilizing bio-active peptides and tyramine-conjugated hyaluronic acids for fast gelation. RESULTS: Conventional acrylated HA-based hydrogels have a gelation time of more than 30 min, whereas hybrid bio-ink has been rapidly gelated within 200 s. Fibroblast cells cultured in this hybrid bio-ink up to 7 days showed >90% viability. As a guidance cue for stem cell differentiation, we immobilized four different bio-active peptides: BMP-7-derived peptides (BMP-7D) and osteopontin for osteogenesis, and substance-P (SP) and Ac-SDKP (SDKP) for angiogenesis. Mesenchymal stem cells cultured in these hybrid bio-inks showed the highest angiogenic and osteogenic activity cultured in bio-ink immobilized with a SP or BMP-7D peptide. This bio-ink was loaded in a three-dimensional (3D) bioprinting device showing reproducible printing features. CONCLUSION: We have developed bio-inks that combine biochemical and mechanical cues. Biochemical cues were able to regulate differentiation of cells, and mechanical cues enabled printing structuring. This multi-functional bio-ink can be used for complex tissue engineering and regenerative medicine.

A Study on the Usefulness of an Ankle Joint Examination Assistive Device using a 3D Printing (3D 프린터를 이용한 발목관절 검사 보조기구의 유용성연구)

  • Dong-Hee Hong;Eun-hye Kim;Young-Cheol Joo
    • Journal of the Korean Society of Radiology
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    • v.17 no.7
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    • pp.1099-1108
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    • 2023
  • The mortise view radiography procedure is an ankle joint examination and observes the presence of trauma, sprain, or dislocation suspected in the ankle joint. The auxiliary equipment used during the mortise view radiography procedure can generate artifacts in the radiograph images and is not diverse enough to be custom-made for each patient; not cost-efficient. The purpose of this study is to create a custom assistive device to support mortise view radiography procedure. This study utilized 3D printing technology to create the mortise view radiography procedure assistive device (ShinHan Device; SHD). The lengths of the tibiotalar joint (TTJ), talar calcaneal joint (TCJ), and medial joint (MJ) were measured and evaluated by five researchers using both SHD and the prototype Hologic tool. The mean ranges were found to be 39.42-39.47 mm for TTJ, 31.41-31.57 mm for TCJ, and 21.21-21.23 mm for MJ while using SHD device. On the other hand, the measurements showed mean ranges of 39.73-39.79 mm for TTJ, 31.46-31.50 mm for TCJ, and 21.31-21.35 mm for MJ while using the Hologic tool. Based on this study results, the error ranges at all positions decreased by 24% for TTJ, 17% for TCJ, and 36% for MJ when using SHD device compared to the Hologic tool. Moreover, when SHD was used, it allowed for a highly reproducible examination posture (ICC = 0.99), and it enabled the acquisition of radiograph images without artifacts, which were present in the Hologic tool.

Cytotoxicity(MTT) evaluation of dental instruments made of polymers (치과용 폴리머 기구의 세포독성(MTT) 평가)

  • Choi, Eun-Mi
    • Journal of the Korea Convergence Society
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    • v.12 no.8
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    • pp.187-195
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    • 2021
  • In order to assess the cell toxicity of 10 instruments made of polymers, the MTT assay which utilizes the L-929 cell was selected. Specimens were eluted at a temperature of 37℃ for 24 hours at a rate of 4g per 20mL, RPMI 1640, and then was positively and negatively contrasted with a control test solution, in accordance with the Notification No. 2020-12 Protocols of Medical Apparatus Biological Safety from the Ministry of Drug and Food Safety. As a result of 24 hours of incubation in 37℃, 5% CO2 Incubator and assessment using an ELISA reader, the results of Intraoral camera indiciated a cellular viability of more than 70% at a 50% eluate. But, the Plastic impression tray, 3D printing tweezer, Impression disposable syringe, Dental floss holder, Hand implant scaler, Surgical retractor, Oral scanner tip, Dental mirror, and the Water pick tip all reported a cellular viability of more than 70% at a 100% eluate, which indicates that do not exhibit cytotoxicity, thus allowing it to be used in contact with the mucous membrane of the oral cavity.

The Role of MMA and EGDMA in Enhancing the Mechanical Properties of PMMA Composites (PMMA 복합재의 기계적 특성 향상을 위한 MMA 및 EGDMA의 역할 연구)

  • Aqila Che Ab Rahman;Shiyoung Yang;Sooman lim
    • Journal of Integrative Natural Science
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    • v.17 no.2
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    • pp.53-58
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    • 2024
  • This study explores the enhancement of mechanical properties in Polymethyl Methacrylate (PMMA) composites through the incorporation of Methyl Methacrylate (MMA) and Ethylene Glycol Dimethacrylate (EGDMA). Utilizing Digital Light Processing (DLP) technology, we conducted a series of experiments to analyze the impact of varying concentrations of MMA and EGDMA on PMMA. The results indicate that while MMA demonstrates non-linear and variable mechanical strength across different PMMA concentrations, EGDMA consistently improves mechanical strength as PMMA concentration increases. This consistent enhancement by EGDMA suggests a stable and predictable reinforcement effect, which is critical for applications requiring high mechanical strength. Our comparative analysis highlights that EGDMA is a more effective additive than MMA for optimizing the mechanical performance of PMMA composites. Specifically, EGDMA's ability to provide uniform reinforcement across various PMMA concentrations makes it ideal for high-strength applications. These findings are significant for material scientists and engineers focused on the design and development of advanced PMMA-based materials. In conclusion, this research underscores the importance of selecting appropriate additives to enhance the mechanical properties of PMMA composites. The superior performance of EGDMA in reinforcing PMMA suggests its potential for broader applications in fields such as automotive, construction, medical devices, and 3D printing. This study provides valuable insights that can guide future research and development in high-performance composite materials, paving the way for innovative applications and improved material efficiency.