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http://dx.doi.org/10.7742/jksr.2020.14.5.537

Comparative Study of Sterilization by Gamma-ray and Electron-Beam  

Jeong, Kyeonghwan (Department of Radiologic Technology, Daegu Health College)
Park, Changhee (Department of Radiologic Technology, Daegu Health College)
Publication Information
Journal of the Korean Society of Radiology / v.14, no.5, 2020 , pp. 537-543 More about this Journal
Abstract
The elderly population in the modern society is growing rapidly due to advance medical technology and minimally invasive surgery. Therefore, as the tendency to use medical device is increasing, pathogenic infection is a concern. Therefore, the first aim of modern medicine is infection prevention in medical place. Recently, patient implants are increasing using 3D printing. Hydroxyapatite is used as a representative material. And, there haven't had currently absorbed dose standard for sterilization of hydroxyapatite discs. Escherichia coli and Streptococcus mutans contaminated on the surface of hydroxyapatite discs were irradiated at each absorbed dose of 0, 0.5, 1.0, 3.0, 5.0 kGy using Gamma-ray of cobalt and Electron-beam of linear accelerator. Then, the number of bacteria was measured in the sample by the decimal dilution method. After sterilization, a non-parametric testing method was performed to compare the survival of Escherichia coli and Streptococcus mutans. As a result, Escherichia coli was sterilized at 1 kGy or more and Streptococcus mutans at 3 kGy or more on absorbed dose. It is considered possible to perform sterilization at a lower value than the recommended absorbed dose of radiation sterilization.
Keywords
Sterilization; Gamma-ray; Electron-beam; E. coli; S. mutans;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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1 S. M. Yu, K. Y. Park, E. Y. Yun, "A Survival Analysis of Nasocomial Urinal Tract Infection", Kor. J. Data Anaysis Society, Vol. 12 No. 3, pp. 1351-1363, 2010.
2 FDA, "Ethylene Oxide, Ethlyene Chlorohydrin, and Ethylene Glycol: Proposed Maximum Residue Limits and Maximum Levels of Exposure", Food and Drug Administration; Washington, DC, USA: 1978. 43 FR 27474
3 ISO, "Part-2: Establishing the Sterilization Dose", 11137-2, 2013
4 J. H. Nam, J. H. Shin, J. Y. Lee, D. H. Lee, "Effects of ionizing and ultraviolet radiation on microbial mutation and DNA damage", Korean Journal of Microbiology, Vol. 53, No. 1, pp. 20-28, 2017.   DOI
5 KCDC, "Guideline for Disinfection and Sterilzation in Healthcare Facilties." Korea Center for Disease control & prevention, 2014.
6 S. H. Kim, E. T. Park, J. H. Kim, "Study of Police Response to Radiation Accidents and Terrorism", Journal of the Korean Society of Radiology, Vol. 11, No. 7, pp. 646-653, 2017.
7 Y. Jeong, J. H. Choi, E. K. Kim, S. M. et. al, "Actual Disinfection and Sterilization Control in Korean Healthcare Facilities", Journal Korean Academy of Fundamentals of Nursing, Vol. 21, No. 4, pp. 392-402, 2014.   DOI
8 MFDS, "A Study on safety management plan for 3D-Printed Medical Device", Korean Ministry of Food&Drug Safety, 2015
9 MFDS, "Evulation for sterilization and packing effectiveness of dental implant", Korean Medical device department, 2015.
10 C. Santos, P. S. Gomes, J. A. Duarte, R. P. Franke, M. M. Almeida, M. E. V. Costa and M. H. Fernandes, "Relevance of the sterilization-induced effects on the properties of different hydroxyapatite nanoparticles and assessment of the osteoblastic cell response", Journal of the Royal Society. Interface, Vol. 9, No. 77, pp. 3397-410, 2012.   DOI
11 T. Y. Kim, J. S. Lee, S. J. Hong, H. S. Kim, K. R. Kwon, "Full mouth rehabilitation of patient with severe dental caries with implant fixed prosthesis fabricated with milling and 3D printing method : a case report", The Journal of Korean Academy of Prosthodontics, Vol. 57, No. 3, pp. 288-295, 2019.   DOI
12 Tatiana Koutchma, Larry Keener, Heidi Kotilainen, "Discordant international regulations of food irradiation are a public health impediment and a barrier to global trade", Global Harmonization Initiative, 2018.
13 D. C. Kim, J. W. Kwon, J. H. Jung, S. M. Kim, "Safety and Performance Evaluation Method of Implantable Medical Device Based on Advanced Technology", Korean Soceity of FDC, Vol. 13, No. 2, pp. 125-131, 2018.
14 B. R. Kim, "A study on an introduction of a medical device clinical evaluation", The Graduate School. Yonsei University, 2020.
15 E. Tartari, V. Weterings, P. Gastmeier, J. Rodríguez Baño, A. Widmer, J. Kluytmans, A. Voss, "Patient engagement with surgical site infection prevention: an expert panel perspective", Korean Journal Society of Manufacturing Process Engineers, Vol. 14, No. 3, pp. 1-8, 2015.