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Effects of Insulin-like Growth Factor in Peritoneal Fluid of Patients with Endometriosis on the Proliferation of Endometrial Stromal Cells (자궁내막증 환자의 복강액내 IGF가 자궁내막 기질세포 증식에 미치는 영향)

  • Kim, Jung-Gu;Suh, Chang-Seok;Kim, Seok-Hyun;Choi, Young-Min;Moon, Shin-Yong;Lee, Jin-Yong
    • Clinical and Experimental Reproductive Medicine
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    • v.26 no.3
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    • pp.331-338
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    • 1999
  • The purposes of this study were to evaluate the effects of insulin-like growth factor (IGF)s in peritoneal fluid (PF) from patients with and without endometriosis on the proliferation of endometrial stromal cells and to investigate the effects of type I IGF receptor antibody on the response of endometrial stromal cells to PF from patients with endometriosis. IGFs in PF from patients with endometriosis (n=14) and without endometriosis (n=10) were measured by immunoradiometric assay and PF samples were divided into low IGF-I PF group (less than 85 ng/ml) and high IGF-I PF group (more than 85 ng/ml). Endometrial stromal cells from patients without endometriosis were cultured in serum free media in the presence or absence of 1 % PF and thymidine incorporation test were used to evaluate the proliferation of endometrial stromal cells. Also cultures were incubated with type I IGF receptor monoclonal antibody (${\alpha}IR_3$) before adding PF. PF from patients with endometriosis and without endometriosis increased thymidine incorporation in endometrial stromal cells. In patients with endometriosis, high IGF-I PF group had high IGF-II levels and resulted in higher thymidine incorporation than low IGF-I PF group but no significant difference in increase in thymidine incorporation between high IGF-I and low IGF-I PF group was noted in patients without endometriosis. There was not a significant correlation between increase in thymidine incorporation and IGF-I levels in PF from patients without endometriosis but in PF from patients with endometriosis. Preincubation with ${\alpha}IR_3$ significantly inhibited the mitogenic response of endometrial stromal cells to PF. Our data indicate that IGF-I in PF may be involved in the growth of ectopic endometrium in patients with endometriosis.

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The Koreans Apology Map: An Analysis of Apologies by Types during the Past 10 Years (한국인의 사과 지형: 지난 10년간 사과문의 조직 및 유형 별 분석)

  • Kim, Yung-Wook;Yang, Jung-Eun
    • Korean journal of communication and information
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    • v.59
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    • pp.180-210
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    • 2012
  • The purpose of the study was to analyze the apologies made in Korea for the past 10 years, and to diagnose how Koreans used crisis communication strategies. For the analysis, typology of crisis communication strategy was adopted from previous study as well as the new typology distinctively found in Korea. Also preferred crisis communication strategies were analyzed by crisis subject, by crisis type and by stage of crisis. Results showed that among the crisis communication strategies, apology and corrective action were the most used strategies, followed by bolstering and appealing to sympathy. Preferred crisis communication also differed by crisis subject, by crisis type and by stage of crisis. When the crisis subject were government or public institutions, when the locus of crisis responsibility was internal, and when the crisis was a controllable human/social crisis, the justification strategy was preferred. The results seemed to be related to the unique cultural characteristics of Koreans, especially to sense of Cheong and Chemyon. Indirect corrective action and transcendence were Chemyon-saving strategies while bolstering and appealing to sympathy were strategies appealing to Cheong. Future study should address the new typology of crisis communication strategy reflecting the cultural characteristic.

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Effects of the Remanent Magnetization on Detecting Signals in Magnetic Flux Leakage System (자기누설탐상시스템에서 배관의 잔류자화가 결함신호에 미치는 영향)

  • Seo, Kang;Jeong, Hyun-Won;Park, Gwan-Soo;Rho, Yong-Woo;Yoo, Hui-Ryong;Cho, Sung-Ho;Kim, Dong-Kyu
    • Journal of the Korean Magnetics Society
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    • v.15 no.6
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    • pp.325-331
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    • 2005
  • The magnetic Hut leakage (MFL) type nondestructive testing (NDT) method is widely used to detect corrosion and defects, mechanical deformation of the underground gas pipelines. The object pipeline is magnetically saturated by the magnetic system with permanent magnet and yokes. Because of the strong magnetic field enough to saturate the pipe, there could be distortion of the sensing signals because of the magnetization of the pipeline itself, To detect the defects precisely, the sensing signals are need to be compensated to eliminate the distortions coming from the media hysteresis. In this paper, the magnetizations of the pipeline in MFL type NDT are analyzed by Preisach model and 3D FEM. The distortions of the sensing signals are analyzed.

Eine Structure of Digital Arteries in Rat (흰쥐 수지동맥의 미세구조에 관한 연구)

  • Kim, Baik-Yoon;Shin, Keun-Nam
    • Applied Microscopy
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    • v.29 no.1
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    • pp.83-94
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    • 1999
  • The ultrastructure of small arterioles and capillaries in the lumbrical muscles of rat digits were studied by electron microscopy and following results were obtained. 1. The diameter of small arterioles of rat digits were $12\sim20{\mu}m$, and it was relatively smaller than human $(30\sim35{\mu}m)$. 2. All the endothelial cells of small arterioles and capillaries in the lumbrical muscles of rat digits were continuous type, and they had typical morphological characteristics of continuous endothelial cells : numerous cytoplasmic pinocytic vesicles and many tight junctions between the endothelial cells. 3. In the small arterioles subendothelial layers were irregularly spaced beneath the basal lamina, and membrane to membrane contacts were found between the endothelial cells and smooth muscle cells. 4. Pericytes were often found nearby capillary endothelium, and their cytoplasmic processes surrounded part of endothelial cells. They were enclosed by basal lamina. 5. Smooth muscle cells in tunica media of small arterioles were only one layered, that is, they were terminal arterioles. Sarcoplasm of smooth muscle cell was divided to 2 areas; homogeneous or filamentous area and non-homogeneous perinuclear area. 6. The tunica adventitia contained fibroblasts with extremely attenuated cytoplasmic processes and collagen fibirls.

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D-$\Pi$-A designed dye chromophores and nanoparticles: optical properties, chemosensor effects and PE/Aramid fiber colorations

  • Son, Young-A;Kim, Su-Ho;Kim, Young-Sung
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2010.03a
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    • pp.40-40
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    • 2010
  • Studies on attractive color changing property of dye chromophore and fluorophore have been greatly enjoyed in the related industrial and research fields such as optoelectronics, chemosensor, biosensor and so on. The optical property based on D-$\Pi$-A intramolecular charge transfer (ICT) system of chromophore molecules can be utilized as suitable sensing probes for checking media polarity and determining colorimetric chemosensing effect, especially heavy metal detection. These finding are obtained by absorption and emission properties. In this work, donor-acceptor D-$\Pi$-A type fluorescent dyes were designed and synthesized with the corresponding donor and acceptor groups. The selected donor moieties might be provided prominent amorphous properties which are very useful in designing and synthesizing functional polymers and in fabricating devices. Another reasons to choose are commercial availabilities in high purity and low price. Donor-bridge-acceptor (D-A) type dyes can produce impressive optical-physical properties, yielding them potentially suitable for applications in the synthesis of small functional organic molecules. Small organic functional molecules have unique advantages, such as better solubility, amorphous character, and represent an area of research which needs to be explored and developed. Currently, their applications in metalorganic compounds is rapidly expanding and becoming widespread in self-assembly processes, photoluminescence applications, chiral organocatalysts, and ingrafts with nanomaterials. Colloidal nanoparticles have received great attentions in recent years. The photophysical properties of nanoparticles, particularly in terms of brightness, photostability, emission color purity and broad adsorption range, are very attractive functions in many applications. To our knowledge background, colloidal nanoparticles have been enjoyed their applications in bio-probe research fields. This research interest can be raised by the advantages of the materials such as high photoluminescence quantum yields, sharp emission band, long-term photostability and broad excitation spectra. In recent, the uses of nanoparticles being embedded in a polymer matrix and binded on polymer surface have been explored and their properties such as photo-activation and strong photoluminescence have been proposed. The prepared chromophores and nanoparticles were investigated with absorption and emission properties, solvatochromic behaviors, pH induced color switching effects, chemosensing effects and HOMO/LUMO energy potentials with computer simulation. In addition, synthesized fluorophore dyes and particles were applied onto PE/Aramid fiber fluorescing colorations. And the related details were then discussed.

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Lightweight video coding using spatial correlation and symbol-level error-correction channel code (공간적 유사성과 심볼단위 오류정정 채널 코드를 이용한 경량화 비디오 부호화 방법)

  • Ko, Bong-Hyuck;Shim, Hiuk-Jae;Jeon, Byeung-Woo
    • Journal of Broadcast Engineering
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    • v.13 no.2
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    • pp.188-199
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    • 2008
  • In conventional video coding, encoder complexity is much higher than that of decoder. However, investigations for lightweight encoder to eliminate motion prediction/compensation claiming most complexity in encoder have recently become an important issue. The Wyner-Ziv coding is one of the representative schemes for the problem and, in this scheme, since encoder generates only parity bits of a current frame without performing any type of processes extracting correlation information between frames, it has an extremely simple structure compared to conventional coding techniques. However, in Wyner-Ziv coding, channel decoding errors occur when noisy side information is used in channel decoding process. These channel decoding errors appear more frequently, especially, when there is not enough correlation between frames to generate accurate side information and, as a result, those errors look like Salt & Pepper type noise in the reconstructed frame. Since this noise severely deteriorates subjective video quality even though such noise rarely occurs, previously we proposed a computationally extremely light encoding method based on selective median filter that corrects such noise using spatial correlation of a frame. However, in the previous method, there is a problem that loss of texture from filtering may exceed gain from error correction by the filter for video sequences having complex torture. Therefore, in this paper, we propose an improved lightweight encoding method that minimizes loss of texture detail from filtering by allowing information of texture and that of noise in side information to be utilized by the selective median filter. Our experiments have verified average PSNR gain of up to 0.84dB compared to the previous method.

Increased Production of an Alkaline Protease from Bacillus clausii I-52 by Chromosomal Integration (Bacillus clausii I-52의 Chromosomal Integration에 의한 Alkaline Protease의 생산성 향상)

  • Joo, Han-Seung;Park, Dong-Chul;Choi, Jang-Won
    • Journal of agriculture & life science
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    • v.46 no.1
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    • pp.163-176
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    • 2012
  • TTo increase productivity of a strong extracellular alkaline protease (BCAP), stable strains of Bacillus clausii I-52 carrying another copy of BCAP gene in the chromosome were developed. Integrative vector, pHPS9-fuBCAP carrying BCAP promoter, ribosome binding site, signal sequence and active protease gene was constructed and transferred into B. clausii I-52, and integration of the constructed plasmid into chromosome was identified by PCR. An investigation was carried out on BCAP production by B. clausii I-52 and transformant C5 showing the highest relative activity of alkaline protease using submerged fermentation. Maximum enzyme activity was produced when cells were grown under the submerged fermentation conditions at $37^{\circ}C$ for 48 h with an aeration rate of 1 vvm and agitation rate of 650 rpm in a optimized medium (soybean meal 2%, wheat flour 1%, sodium citrate 0.5%, $K_2HPO_4$ 0.4%, $Na_2HPO_4$ 0.1%, NaCl 0.4%, $MgSO_47H_2O$ 0.01%, $FeSO_47H_2O$ 0.05%, liquid maltose 2.5%, $Na_2CO_3$ 0.6%). A protease yield of approximately 134,670U/ml was achieved using an optimized media, which show an increase of approximately 1.6-fold compared to that of non-transformant (83,960 U/ml). When the stability of transformant C5 was examined, the integrated plasmid pHPS9-fuBCAP was detected in the transformant after cultivation for 8 days, suggesting that it maintained stably in the chromosomal DNA of transformant C5.

A study on the effect of online learning according to the difference between personal and social motivation after COVID-19 (COVID-19 이후 개인적 동기와 사회적 동기차이에 따른 온라인 학습효과 연구)

  • Chin, HongKun
    • Journal of the Korea Convergence Society
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    • v.12 no.9
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    • pp.113-120
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    • 2021
  • As a result, the interaction between personal motivation and class type is not significant. On the other hand, the interaction between social motivation and class type is significant and overall online class increases engagement with educational issues. In particular, the group with low social motivation showed greater change than the group with high social motivation, so online education seems to be more effective in the group with low social motivation. It means that by stimulating students' social motivation rather than personal motivation, the effectiveness of online education can be enhanced, and it can lead to education outcomes - behavioral changes and attitudes of learners. In order to revitalize social motivation in the intensely personal space of online, it is necessary to activate social communication methods such as SNS, and development of interpersonal issues and learning materials would be more efficient. In order to derive more specific results, it is necessary to measure the level of prior knowledge and involvement of the participants in class, and to comprehensively investigate and analyze the state of learners before and after class through more variables. Finally, in order to increase the reliability of the research results, it is necessary to clearly prove it through the establishment of a structural model.

Persuasive Effects of Message Framing and Source on the Attitudes and Behavior Intention for Drunk Driving Prevention: Focusing on Vietnamese Motorbike Driver (메시지 프레이밍과 정보원 유형이 음주운전 예방캠페인의 설득효과에 미치는 영향: 베트남 오토바이 운전자를 중심으로)

  • Nguyen, Thanh-Mai;Ha, Ji-Young;Jo, Sam-Sup
    • The Journal of the Korea Contents Association
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    • v.19 no.8
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    • pp.137-150
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    • 2019
  • In this study, we investigated the joint effects of message framing (profit vs. loss) and source type (celeb vs. general) on the persuasive effectiveness of mass media campaign to prevent drunk driving. As a result of conducting an experimental study on 218 motorcycle drivers in Vietnam, the main effects of message framing were not significant, but the interaction effect with the type of information source consistently influenced the attitude toward the advertisement, the drunk driving prevention, and the behavior intention Specifically, it is more persuasive to send a message by a general model rather than an celebrity when the loss framing method is used while it is more persuasive to send a message by a celebrity model than a general model when the gain framing is used. This study therefore provided valuable information and practical implication to the National Traffic Safety Committee of Vietnam for establishing a campaign to prevent drunk driving. In addition, this research also has valuable theoretical implication because it examines the effect of drunk driving prevention campaign on the attitude toward not only advertisement and the drunk driving prevention but also the behavior intention.

The Effect of Task-Oriented Multi-Sensory Movement Program on Self-efficacy and Writing Ability of Children with ADHD Tendency Accompanied by Learning Delays (과제 중심 다감각운동 프로그램이 학습지연을 동반한 ADHD성향 아동의 자아효능감과 쓰기능력에 미치는 변화)

  • Roh, Heo-Lyun;Kwag, Sung-Won
    • The Journal of Korean society of community based occupational therapy
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    • v.8 no.2
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    • pp.1-14
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    • 2018
  • Objective : The purpose of this study was to investigate the change in self-efficacy and writing ability after applying a Task-Oriented Multi-Sensory Movement Program to children with ADHD tendency accompanied by learning delays. Methods : A Task-Oriented Multi-Sensory Movement Program was implemented to children with ADHD tendency accompanied by learning delays attending S elementary school. The research proceeded in the order of a pre-test, Task-Oriented Multi-Sensory Movement intervention, and a post-test. The first session involved a pre-test, in which the children's self-efficacy and writing ability were examined using self-efficacy test and type 'A' KNISE-BAAT writing test. The multisensory group activity program intervention was conducted for a total of 8 sessions. In the last session, a post-test was conducted using self-efficacy test and type 'B' KNISE-BAAT writing test. Data collected from the tests were analyzed using SPSS Statistics 18. Results : According to the tests taken before and after implementing the Task-Oriented Multi-Sensory Movement Program, there was a significant improvement in self-efficacy (school, society), writing ability(command of vocabulary and sentence). Conclusion : Task-Oriented Multi-Sensory Movement Program may be used as a beneficial measure to improve the self-efficacy and writing abilities of children with ADHD tendency accompanied by learning delays. It is necessary to design various intervention models by combining educational media based on a multisensory approach.