• 한방재활의학과학회지
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• 제26권3호
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• pp.17-30
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• 2016

Objectives The purpose of this study was to find out the effects of ChondroT on arthralgia of the Collagenase-induced osteoarthritis in rats. Methods Osteoarthritis was induced into rat by injecting Collagenase in its knee joint. Rats are divided into a total of 8 groups (n=6). Normal group was not induced for osteoarthritis whereas control groups were induced for osteoarthritis by Collagenase. Positive-A (Indomethacin) was injected with Collagenase and after 8 days, 2 mg/kg of Indomethacin was medicated. Positive-B (JOINS TAB) was injected with Collagenase and after 8 days, 20 mg/kg of JOINS TAB was medicated. Experimental groups (Chondro T) at three dose levels (50, 100 and 200 mg/kg) were injected with Collagenase and after 8days they were medicated with 10 ml/kg. Indomethacin, JOINS TAB and ChondroT were medicated each substances once a day for 10 days. Thereafter, the changes in plantar withdrawal response of osteoarthritis rats by dynamic plantar aesthesiometer were observed and then RT-PCR analysis was done to investigate the expression of related proteins. Results 1. ChondroT significantly decreased withdrawal response of mechanical allodynia compared with control group in all of the experimental groups (ChondroT-A, ChondroT-B, ChondroT-C). 2. ChondroT significantly reduced Bax/Bcl-2 ratio in all of the experimental groups (ChondroT-A, ChondroT-B, ChondroT-C). 3. ChondroT significantly reduced the expression of INF-${\gamma}$ compared with control group in group ChondroT-B, ChondroT-C. Conclusions This results suggest that ChondroT may be meaningful for suppressing the pain of osteoarthritis. Further study is needed to conduct a rigorous clinical research.

• 한국세라믹학회지
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• 제55권5호
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• pp.492-497
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• 2018

This paper reports the efficacy of tape casting using an Ag-10 wt% CuO filler for the successful joining of a sintered $Ce_{0.9}Gd_{0.1}O_{2-{\delta}}-La_{0.7}Sr_{0.3}MnO_{3{\pm}{\delta}}$ (GDC-LSM) ceramic with a SUS 460 FC metal alloy by reactive air brazing. The as-prepared green tape was highly flexible without drying cracks, and the handling was easy when used as a filler material for reactive air brazing. Heat treatment for the GDC-LSM/SUS 460 FC joint was performed at $1050^{\circ}C$ for 30 min in air. Microstructural observations indicated a reliable and compact joining. The room temperature mechanical shear strength of the as-brazed joints was $60{\pm}8MPa$ with a cohesive failure. The flexural strength of joints was measured from room temperature up to $850^{\circ}C$, where the strength retention revealed to be almost 100% at $500^{\circ}C$. However, the joints showed a degradation in strengths at 800 and $850^{\circ}C$, exhibiting strength retentions of 57% and 37%, respectively.

• 한국공간구조학회논문집
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• 제12권2호
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• pp.81-88
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• 2012

텐세그리티 구조시스템의 한 종류인 케이블 돔 시스템은 케이블과 마스트로 이루어져 있다. 이 케이블에 외부하중이 가해지지 않은 상태에서 안정된 구조물이 되기 위하여 일정의 프리텐션이 가해져야 하며 구조물은 가해진 프리텐션 하에서 자기평형응력상태에 있어야 한다. 본 연구에서는 부재의 내력 벡터의 합 원리를 기초하여 자기평형 응력모드를 구하는 새로운 방법을 제안하였으며, 자기평형응력을 유지하기 위해 필요한 응력모드를 시각화할 수 있다는 점이 기존의 논문과 비교하여 독특성을 갖는다. 본 연구에서 제안된 방법에서 사용된 기본 원리는 모든 절점에서 외부하중이 가해지지 않은 상태에서 내력벡터의 합은 0이 되어야 한다는 것이다. 제안된 방법은 CAD를 이용하여 간단히 자기 평형응력모드를 찾을 수 있으며, 예제 케이블 돔 구조물을 대상으로 각 절점에 연결된 부재들의 내력을 결정하였다. 결과 값은 역학적 계산 방법과 기존의 이론에 의해 검증하였으며 잘 일치하였다.

• 전기학회논문지
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• 제61권12호
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• pp.1911-1919
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• 2012

In this paper, we focus on a robotic sealing process in which three robots are used. Each robot can be considered as a 7 axis redundant robot of which the first joint is prismatic and the last 6 joints are revolute. In the factory floor, robot path planning is not a simple problem and is not automated. They need experienced operators who can operate robots by teaching and playing back fashion. However, the robotic sealing process is well organized so the relative positions and orientations of the objects in the floor and robot paths are all pre-determined. Therefore by adopting robotic theory, we can optimally plan robot pathes without using teaching. In this paper, we analyze the sealing robot by using redundant manipulator theory and propose three different methods for path planning. For sealing paths outside of a car body, we propose two methods. The first one is resolving redundancy by using pseudo-inverse of Jacobian and the second one is by using weighted pseudo-inverse of Jacobian. The former is optimal in the sense of energy and the latter is optimal in the sense of manipulability. For sealing paths inside of a car body, we must consider collision avoidance so we propose a performance index for that purpose and a method for optimizing that performance index. We show by simulation that the proposed method can avoid collision with faithfully following the given end effector path.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 심포지엄 논문집 정보 및 제어부문
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• pp.315-316
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• 2007

This paper presents a new methodology to improve movement database for a humanoid robot. The database is initially full of human motions so that the kinetics characteristics of human movement are immanent in it. then, the database is updated to the pseudo-optimal motions for the humanoid robot to perform more natural motions, which contain the kinetics characteristics of robot. for this, we use the evolutionary algorithm. the methodology consists of two processes : (1) the offline imitation learning of human movement and (2) the online generation of natural motion. The offline process improve the initial human motion database using the evolutionary algorithm and inverse dynamics-based optimization. The optimization procedure generate new motions using the movement primitive database, minimizing the joint torque. This learning process produces a new database that can endow the humanoid robot with natural motions, which requires minimal torques. In online process, using the linear combination of the motion primitive in this updated database, the humanoid robot can generate the natural motions in real time. The proposed framework gives a systematic methodology for a humanoid robot to learn natural motions from human motions considering dynamics of the robot. The experiment of catching a ball thrown by a man is performed to show the feasibility of the proposed framework.

• Advances in aircraft and spacecraft science
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• 제3권2호
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• pp.171-195
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• 2016

The present paper is a review of the main activities carried out within the context of the COMPTINN' program, a joint research project founded by a FUI program (Fonds $Unifi{\acute{e}}s$ $Interminist{\acute{e}}riels$) in which four research teams focused on the thermo-oxidation behaviour of HTS-TACTIX carbon-epoxy composite at 'high' temperatures ($120^{\circ}C-180^{\circ}C$). The scientific aim of the COMPTINN' program was to better identify, with a multi-scale approach, the link between the physico-chemical mechanisms involved in thermo-oxidation phenomena, and to provide theoretical and numerical tools for predicting the mechanical behaviour of aged composite materials including damage onset and development.

• 대한골관절종양학회지
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• 제8권2호
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• pp.48-53
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• 2002

상피암의 인접 골격근으로의 직접 전파는 많이 보고되었으나, 골격근으로의 원격전이는 드물고 특히 다발성 전이는 매우 드문 것으로 알려져 있다. 골격근내의 가변적인 혈류량, 근수축이나 난류성 혈류 등과 같은 물리적인 요인, 골격근내의 산성 환경, 젖산, 세포외 기질의 단백분해효소 억제인자 등이 골격근으로의 원격 전이를 억제하는 원인으로 제시되고 있다. 저자들은 최근 다발성 골격근 전이를 동반한 신장암(이행성 상피세포암) 1례를 경험하였기에 이를 보고하는 바이다.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제12권1호
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• pp.49-59
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• 2006

According to the increase of demand for human organs such as kidney, heart, pancreas, joint, and cornea for therapeutic transplantation, the production of alternative organs based on Gnotobiotic Pigs gains a lot of concerns all over the world. However, it is not common to design and build Gnotobiotic Pigs' facility, and there are only a few those facilities and planning principles for them. Considering the situation above, this paper tries to develop planning guidelines for space organization and circulation system of standardized Germ Free Pig's facility on the bases of case analysis. The results of this study are as follows. At first, four swine farms including a Gntobiotic Pig's facility has been analysed from the point of space organization and circulation system. Secondly, the space zoning of Gnotobiotic Pigs' facility has been proposed into 5 groups : pigs' area, adminstration area, operating room and laboratory, service area, and mechanical area. Space components of each group have been presented also. Finally, circulation system of Gnotobiotic Pigs' facility has been explored from a operational point of view. This, also, includes human circulation, pig's circulation, and goods' circulation. This study has some limitations because it does not consider the SOPs(standard operational policies) of that facility to the fullest measure and does not suggest space area of each part, either. Despite of some weaknesses, it is expected that this study can give some useful guidelines for the design and planning of Germ Free Pigs' facilities.

• 한국자동차공학회논문집
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• 제15권1호
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• pp.116-124
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• 2007

An optical method to measure the size and number density of soot aggregates in diesel exhaust has been proposed in this study. Two laser beams in co-axial alignment transmit a soot loaded exhaust gas flow, and the transmittance at each wavelength is detected by a photo diode simultaneously. The volume equivalent diameter and number density of soot aggregates in the optical path can be theoretically given by the transmittance values measured at two wavelengths. A test conducted by a single cylinder, 4 cycle, small and DI diesel engine shows that the temporal variations of the size and number density of soot aggregates in the diesel exhaust can be measured by the proposed method at a transient mode operation. It is found that the volume equivalent diameter varied temporally from 70 to 110 nm during the period that high soot concentration is observed. One can also conclude that the optical length longer than 1 m in the dynamic range regarding this method is preferable for measuring soot concentration at the level of $1\;mg/m^3$.

• 대한의용생체공학회:의공학회지
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• 제29권1호
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• pp.40-45
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• 2008

Therapeutic ultrasound which is developed for rehabilitation therapy have already been used for healing joint contracture, synechia, acute and chronic inflammatory diseases. Medical devices for pain-relief and healing using therapeutic ultrasound are actively being developed. This study measured the change of PTT with the transmitted ultrasound through the human body to find out the increase of compliance of blood vessels. Measurement method of PTT in this study is employed as useful ways to acquire physiological information of patients in the clinical case in order to measure the change of mechanical characteristics of blood vessels. This study confirmed the PTT change of rehabilitation patients through the thermal effects of ultrasound by using PTT and also found that it is possible to increase PTT by adjusting the warm water and ultrasound. The increase of PTT means the decrease of the pulse wave velocity from the cardiovascular system to the peripheral arteries. The physiological effects occurred using the warm water and ultrasound.