• Therapeutic Science for Rehabilitation
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• v.10 no.3
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• pp.83-96
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• 2021

Objective : This study aimed to determine Korea-type family function factors that affect individual growth and social activities, and examine check the appropriate contents and domestic culture components based on the McMaster model, a family function evaluation tool, through the Delphi technique. Methods : The Delphi technique was applied to 12 expert panels in fields related to family function. The period lasted 9 weeks, from May to June 2020. The Delphi survey was conducted twice. In the first survey, the domestic culture and appropriate contents of the McMaster model were selected and localized, and expert' opinions about the components were collected using closed and open-ended questions. In the second survey, the fitness and importance of the components were investigated. Results : As a result of the first Delphi investigation, 18 items were deleted from the 53 items presented. After adding 11 items and excluding any overlapping items, a total of 40 items were selected. Subsequently, sentences that were difficult to understand were revised to familiar vocabulary. A second survey was constructed, with an example sentence. In the second Delphi investigation, 33 items were selected. The average content validity ratio for the final selected component was 0.76, and the stability was 0.28. Conclusion : Family function and the factors influencing domestic family function identified though this study can be used to conduct family function evaluations and interventions in clinical sites or relevant research studies.

• Journal of Energy Engineering
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• v.9 no.4
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• pp.358-365
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• 2000

본 연구에서는 수직 단일관에서의 재관수(reflux) 응축 현상에서 증기유량이 역류제한치보다 큰 경우에 발생하는 다양한 유동 패턴을 예측하고, 그 동적 특성을 해석하기 위한 모델을 개발하였다. 특히 L/D가 큰 재관수 응축기에서 발생하는 충전 방출 모드에서의 동적 특성을 예측하는 것이 목표이다. 응축기의 내부를 액체와 증기의 두 영역으로 나누어 질량, 에너지, 운동량 보존에 입각한 본 모델은, 형성된 물기둥의 진동시 갈래질 경계(bifurcation boundary)와 진동주기를 예측할 수 있다. 이 모델은 McMaster 대학에서 수행한 실험결과와 비교한 결과 양호한 예측을 했고, 튜브 직경변화 효과를 잘 묘사하였다. 이러한 단순 모델은 재관수 응축기의 설계시에 설계변수를 도출하는데 사용될 수 있고, 인위적으로 부여한 압력펄스를 이용하여 재관수 응축기의 운전영역을 개선하는데 기초로 활용될 수 있다.

• Geophysics and Geophysical Exploration
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• v.13 no.1
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• pp.40-50
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• 2010

The building process of any geological map involves linking sparse lithological outcrop information with equally sparse geometrical measurements, all in a single entity which is the preferred interpretation of the field geologist. The actual veracity of this interpretative map is partially dependent upon the frequency and distribution of geological outcrops compounded by the complexity of the local geology. Geophysics is commonly used as a tool to augment the distribution of data points, however it normally does not have sufficient geometrical constraints due to: a) all geophysical inversion models being inherently non-unique; and b) the lack of knowledge of the physical property contrasts associated with specific lithologies. This contribution proposes the combined use of geophysical edge detection routines and 'three point' solutions from topographic data as a possible approach to obtaining geological contact geometry information (strike and dip), which can be used in the construction of a preliminary geological model. This derived geological information should first be assessed for its compatibility with the scale of the problem, and any directly observed geological data. Once verified it can be used to help constrain the preferred geological map interpretation being developed by the field geologist. The method models the contacts as planar surfaces. Therefore, it must be ensured that this assumption fits the scale and geometry of the problem. Two examples are shown from folded sequences at the Bathurst Mining Camp, New Brunswick, Canada.

• Journal of Soil and Groundwater Environment
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• v.13 no.6
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• pp.40-49
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• 2008

Matrix diffusion from planar fractures was studied mathematically and through physical model experiments. Mathematical models were developed to simulate diffusion from 2D and 3D instantaneous disk sources and a 3D continuous disk source. The models were based on analytical solutions previously developed by Carslaw and Jaeger (1959). The mathematical simulations indicated that the 2D scenario produces significantly different results from the 3D scenario, the time for mass disappearance is significantly larger for continuous sources than for instantaneous sources, the normalized concentration generally decreased over time for instantaneous sources while it increased over time for continuous sources, diffusion rates decrease significantly over time and space, and the normalized mass loss from the source zone never reaches 1 for continuous sources due to the semi-infinite integral. The simulations also showed that disappearance times increase exponentially with increasing source radii and matrix porosity, and decrease with increasing aqueous-phase NAPL solubilities.

• Journal of Life Science
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• v.34 no.5
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• pp.339-355
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• 2024

The pulmonary system is a highly complex system that can only be understood by integrating its functional and structural aspects. Hence, in vivo animal models are generally used for pathological studies of pulmonary diseases and the evaluation of inhalation toxicity. However, to reduce the number of animals used in experimentation and with the consideration of animal welfare, alternative methods have been extensively developed. Notably, the Organization for Economic Co-operation and Development (OECD) and the United States Environmental Protection Agency (USEPA) have agreed to prohibit animal testing after 2030. Therefore, the latest advances in biotechnology are revolutionizing the approach to developing in vitro inhalation models. For example, lung organ-on-a-chip (OoC) and organoid models have been intensively studied alongside advancements in three-dimensional (3D) bioprinting and microfluidic systems. These modeling systems can more precisely imitate the complex biological environment compared to traditional in vivo animal experiments. This review paper addresses multiple aspects of the recent in vitro modeling systems of lung OoC and organoids. It includes discussions on the use of endothelial cells, epithelial cells, and fibroblasts composed of lung alveoli generated from pluripotent stem cells or cancer cells. Moreover, it covers lung air-liquid interface (ALI) systems, transwell membrane materials, and in silico models using artificial intelligence (AI) for the establishment and evaluation of in vitro pulmonary systems.