• 제목/요약/키워드: McDonald

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Effects of Genetic Variants of ${\kappa}$-casein and ${\beta}$-lactoglobulin and Heat Treatment of Milk on Cheese and Whey Compositions

  • Choi, J.W.;Ng-Kwai-Hang, K.F.
    • Asian-Australasian Journal of Animal Sciences
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    • 제15권5호
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    • pp.732-739
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    • 2002
  • Milk samples with different phenotype combination of $\{kappa}$-casein and ${\beta}$-lactoglobulin and different preheating temperatures of 30, 70, 75 and $80^{\circ}C$ were used for cheesemaking under laboratory conditions. For the 853 batches of cheese, mean composition was 59.64% total solids, 30.24% fat and 23.66% protein, and the whey contained 6.93% total solids, 0.30% fat and 0.87% protein. Least squares analysis of the data indicated that heating temperature of the milk and ${\kappa}$-CN/${\beta}$-LG phenotypes had significant effects on cheese and whey compositions. The total solids, fat and protein contents of cheese were negatively correlated with preheating temperatures of milk. Cheese from BB/BB phenotype milk had the highest and those from AA/AA phenotype milk had the lowest concentrations of total solids, fat and protein. Mean recoveries of milk components in the cheese were 53.71% of total solids, 87.15% of fat, and 80.32% of protein. For the 10 different types of milk, maximum recoveries of milk components in cheese occurred with preheating temperature of $70^{\circ}C$ or $75^{\circ}C$ and lowest recoveries occurred at $80^{\circ}C$. The whey averaged 6.94% total solids, 0.30% fat and 0.87% protein. Losses of milk components in the whey were lowest for milk preheated at $80^{\circ}C$ and for milk containing the BB/BB phenotype.

패스트푸드점 DID에 나타난 GUI 디자인 연구 - 롯데리아, 맥도날드, 버커킹, 맘스터치 중심으로 - (Study of GUI Design appearing in Fast Food Restaurant DID - Focused on Lotteria, McDonald's, Burger King and Mom's Touch -)

  • 이영화
    • 한국융합학회논문지
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    • 제10권11호
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    • pp.253-262
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    • 2019
  • 본 논문에서는 패스트푸드점 DID에 나타난 GUI 디자인을 알아보기 위하여 사용자를 대상으로 실태조사를 실시하였다. 이를 바탕으로 2017년 햄버거 업계 매출이 높은 롯데리아, 맥도날드, 버거킹, 맘스터치 네 곳을 선정하고, DID에 나타난 GUI 시각적 구성요소인 레이아웃, 문자, 색채, 그래픽, 동영상 등을 살펴보고 분석하였다. 그 결과 효율적인 GUI 디자인을 위해 패스트푸드점의 환경적 요인을 분석하여 복잡한 접근보다는 구분이 명확하고 정돈된 레이아웃, 주목성과 가독성이 높은 문자, 시인성이 높은 색채, 흥미를 유도하는 그래픽, 다양한 콘텐츠의 동영상을 사용자에 제공하는 디자인 방안을 제안할 수 있었다.

Psychometric Properties of the Fall Risk Perception Questionnaire-Short Version for Inpatients in Acute Care Hospitals

  • Choi, Jeeeun;Lee, Sujin;Park, Eunjin;Ku, Sangha;Kim, Sunhwa;Yu, Wonhye;Jeong, Eunmi;Park, Sukhee;Park, Yusun;Kim, Hye Young;Kim, Sung Reul
    • 대한간호학회지
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    • 제54권2호
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    • pp.151-161
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    • 2024
  • Purpose: Patients' perception of fall risk is a promising new indicator for fall prevention. Therefore, a fall risk perception questionnaire that can be used rapidly and repeatedly in acute care settings is required. This study aimed to develop a short version of the fall risk perception questionnaire (Short-FRPQ) for inpatients. Methods: For the psychometric measurements, 246 inpatients were recruited from an acute care hospital. The construct (using confirmatory factor analysis and discriminant validity of each item), convergent, and known-group validities were tested to determine the validity of the Short-FRPQ. McDonald's omega coefficient was used to examine the internal consistency of reliability. Results: In the confirmatory factor analysis, the fit indices of the Short-FRPQ, comprising 14 items and three factors, appeared to be satisfactory. The Short-FRPQ had a significantly positive correlation with the original scale, the Korean Falls Efficacy Scale-International, and the Morse Fall Scale. The risk of falls group, assessed using the Morse Fall Scale, had a higher score on the Short-FRPQ. McDonald's omega coefficient was .90. Conclusion: The Short-FRPQ presents good reliability and validity. As patient participation is essential in fall interventions, evaluating the fall risk perception of inpatients quickly and repeatedly using scales of acceptable validity and reliability is necessary.

IGRINS Design and Performance Report

  • Park, Chan;Jaffe, Daniel T.;Yuk, In-Soo;Chun, Moo-Young;Pak, Soojong;Kim, Kang-Min;Pavel, Michael;Lee, Hanshin;Oh, Heeyoung;Jeong, Ueejeong;Sim, Chae Kyung;Lee, Hye-In;Le, Huynh Anh Nguyen;Strubhar, Joseph;Gully-Santiago, Michael;Oh, Jae Sok;Cha, Sang-Mok;Moon, Bongkon;Park, Kwijong;Brooks, Cynthia;Ko, Kyeongyeon;Han, Jeong-Yeol;Nah, Jakyuong;Hill, Peter C.;Lee, Sungho;Barnes, Stuart;Yu, Young Sam;Kaplan, Kyle;Mace, Gregory;Kim, Hwihyun;Lee, Jae-Joon;Hwang, Narae;Kang, Wonseok;Park, Byeong-Gon
    • 천문학회보
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    • 제39권2호
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    • pp.90-90
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    • 2014
  • The Immersion Grating Infrared Spectrometer (IGRINS) is the first astronomical spectrograph that uses a silicon immersion grating as its dispersive element. IGRINS fully covers the H and K band atmospheric transmission windows in a single exposure. It is a compact high-resolution cross-dispersion spectrometer whose resolving power R is 40,000. An individual volume phase holographic grating serves as a secondary dispersing element for each of the H and K spectrograph arms. On the 2.7m Harlan J. Smith telescope at the McDonald Observatory, the slit size is $1^{{\prime}{\prime}}{\times}15^{{\prime}{\prime}}$. IGRINS has a plate scale of 0.27" pixel-1 on a $2048{\times}2048$ pixel Teledyne Scientific & Imaging HAWAII-2RG detector with a SIDECAR ASIC cryogenic controller. The instrument includes four subsystems; a calibration unit, an input relay optics module, a slit-viewing camera, and nearly identical H and K spectrograph modules. The use of a silicon immersion grating and a compact white pupil design allows the spectrograph collimated beam size to be 25mm, which permits the entire cryogenic system to be contained in a moderately sized ($0.96m{\times}0.6m{\times}0.38m$) rectangular Dewar. The fabrication and assembly of the optical and mechanical components were completed in 2013. From January to July of this year, we completed the system optical alignment and carried out commissioning observations on three runs to improve the efficiency of the instrument software and hardware. We describe the major design characteristics of the instrument including the system requirements and the technical strategy to meet them. We also present the instrumental performance test results derived from the commissioning runs at the McDonald Observatory.

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The hepatocyte growth factor/c-Met signaling pathway as a therapeutic target to inhibit angiogenesis

  • You, Weon-Kyoo;McDonald, Donald M.
    • BMB Reports
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    • 제41권12호
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    • pp.833-839
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    • 2008
  • Angiogenesis in tumors is driven by multiple growth factors that activate receptor tyrosine kinases. An important driving force of angiogenesis in solid tumors is signaling through vascular endothelial growth factor (VEGF) and its receptors (VEGFRs). Angiogenesis inhibitors that target this signaling pathway are now in widespread use for the treatment of cancer. However, when used alone, inhibitors of VEGF/VEGFR signaling do not destroy all blood vessels in tumors and do not slow the growth of most human cancers. VEGF/VEGFR signaling inhibitors are, therefore, used in combination with chemotherapeutic agents or radiation therapy. Additional targets for inhibiting angiogenesis would be useful for more efficacious treatment of cancer. One promising target is the signaling pathway of hepatocyte growth factor (HGF) and its receptor (HGFR, also known as c-Met), which plays important roles in angiogenesis and tumor growth. Inhibitors of this signaling pathway have been shown to inhibit angiogenesis in multiple in vitro and in vivo models. The HGF/c-Met signaling pathway is now recognized as a promising target in cancer by inhibiting angiogenesis, tumor growth, invasion, and metastasis.

Effects of Pseudomonas aureofaciens 63-28 on Defense Responses in Soybean Plants Infected by Rhizoctonia solani

  • Jung, Woo-Jin;Park, Ro-Dong;Mabood, Fazli;Souleimanov, Alfred;Smith, Donald L.
    • Journal of Microbiology and Biotechnology
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    • 제21권4호
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    • pp.379-386
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    • 2011
  • The objective of this work was to investigate the ability of the plant growth-promoting rhizobacterium Pseudomonas aureofaciens 63-28 to induce plant defense systems, including defense-related enzyme levels and expression of defense-related isoenzymes, and isoflavone production, leading to improved resistance to the phytopathogen Rhizoctonia solani AG-4 in soybean seedlings. Seven-day-old soybean seedlings were inoculated with P. aureofaciens 63-28, R. solani AG-4, or P. aureofaciens 63-28 plus R. solani AG-4 (P+R), or not inoculated (control). After 7 days of incubation, roots treated with R. solani AG-4 had obvious damping-off symptoms, but P+R-treated soybean plants had less disease development, indicating suppression of R. solani AG-4 in soybean seedlings. Superoxide dismutase (SOD) and catalase (CAT) activities of R. solani AG-4-treated roots increased by 24.6% and 54.0%, respectively, compared with control roots. Ascorbate peroxidase (APX) and phenylalanine ammonia lyase (PAL) activities of R. solani AG-4-treated roots were increased by 75.1% and 23.6%, respectively. Polyphenol oxidase (PPO) activity in soybean roots challenged with P. aureofaciens 63-28 and P+R increased by 25.0% and 11.6%, respectively. Mn-SOD (S1 band on gel) and Fe-SOD (S2) were strongly induced in P+R-treated roots, whereas one CAT (C1) and one APX (A3) were strongly induced in R. solani AG-4- treated roots. The total isoflavone concentration in P+Rtreated shoots was 27.2% greater than the control treatment. The isoflavone yield of R. solani AG-4-treated shoots was 60.9% less than the control.

IGRINS and the Revolution in High Resolution Infrared Spectroscopy

  • Jaffe, Daniel T.
    • 천문학회보
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    • 제40권1호
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    • pp.41.4-42
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    • 2015
  • The Immersion Grating Infrared Spectrograph (IGRINS) is the first of a new generation of infrared instruments with high sensitivity, high spectral resolution, and broad spectral grasp. IGRINS, a joint project of the University of Texas and the Korea Astronomy and Space Science Institute, designed and constructed by a team at UT, KASI, and Kyung Hee University, has been available to the Korean and Texas communities on the McDonald Observatory 2.7m telescope since 2014 September. On this modest-sized telescope, the instrument has 30 times the spectral grasp of CRIRES at the 8m VLT and is only slightly less sensitive. Already, Korean and UT astronomers have produced a raft of new results in star formation studies, investigations of the interstellar medium, and the nature of cool stars. Several programs are under way to detect and study the atmospheres of exoplanets. We will present highlights from the first 6 months of IGRINS operations and look at the future of IR spectroscopy both with IGRINS and with GMTNIRS, a UT/KASI/KHU instrument for the Giant Magellan Telescope.

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IGRINS : 1st Year Operation & Future Plan

  • 이재준;김휘현;황나래;박찬;박병곤
    • 천문학회보
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    • 제40권2호
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    • pp.43.1-43.1
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    • 2015
  • After successful commissioning observations in 2014, Immersion Grating Infrared Spectrograph (IGRINS) has been conducting its normal scientific operations on the 2.7m Harlan J. Smith telescope at the McDonald Observatory and has been producing high spectral resolution near-infrared spectroscopic data in excellent quality. We will present the current status of the instrument and its software packages, and highlight initial scientific results. In particular, we will discuss possibilities of having IGRINS on larger telescopes.

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랜덤화 블록 모형에서 정렬 방법을 이용한 비모수 다중비교법 (Nonparametric Multiple Comparison Procedure Using Alignment Method Under Randomized Block Design)

  • 한지웅;김동재
    • 응용통계연구
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    • 제19권3호
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    • pp.555-564
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    • 2006
  • 랜덤화 블록 모형하에서의 비모수 다중비교방법으로는 Friedman 순위합 다중비교 방법(McDonald와 Thompson, 1967)이 있다. 이 방법은 블록내 순위를 이용하여 블록간 정보를 이용하지 못하였다. 이런 단점을 보완하기 위하여 본 논문에서는 Hodges와 Lehmann(1962)이 제안한 정렬방법을 이용한 새로운 비모수 다중비교방법을 제안한다. 또한 모의실험을 통하여 여러 다중비교방법의 검정력을 비교하였다.

Alignment estimation performance of Multiple Design Configuration Optimization for three optical systems

  • Oh, Eun-Song;Kim, Seong-Hui;Kim, Yun-Jong;Lee, Han-Shin;Kim, Sug-Whan
    • 한국우주과학회:학술대회논문집(한국우주과학회보)
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    • 한국우주과학회 2011년도 한국우주과학회보 제20권1호
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    • pp.31.1-31.1
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    • 2011
  • In this study, we investigated alignment state estimation performances of the three methods i.e. merit function regression (MFR), differential wavefront sampling (DWS) and Multiple Design Configuration Optimization (MDCO). The three target optical systems are 1) a two-mirror Cassegrain system for deep space Earth observation, 2) intermediate size three-mirror anastigmat for Earth ocean monitoring, and 3) extremely large segmented optical system for astronomical observation. We ran alignment state estimation simulation for several alignment perturbation cases including 1mm to 10mm in decenter and from 0.1 to 1 degree in tilt perturbation error for the two-mirror Cassegrain system. In general, we note that MDCO shows more competitive estimation performance than MFR and DWS. The computational concept, case definition and the simulation results are discussed with implications to future works.

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